{"id":"https://openalex.org/W4362633286","doi":"https://doi.org/10.1158/1940-6207.22533122.v1","title":"Supplementary tables and figure from Aspirin-Induced Chemoprevention and Response Kinetics Are Enhanced by PIK3CA Mutations in Colorectal Cancer Cells","display_name":"Supplementary tables and figure from Aspirin-Induced Chemoprevention and Response Kinetics Are Enhanced by PIK3CA Mutations in Colorectal Cancer Cells","publication_year":2023,"publication_date":"2023-04-03","ids":{"openalex":"https://openalex.org/W4362633286","doi":"https://doi.org/10.1158/1940-6207.22533122.v1"},"language":"en","primary_location":{"id":"doi:10.1158/1940-6207.22533122.v1","doi":"https://doi.org/10.1158/1940-6207.22533122.v1","is_oa":true,"landing_page_url":"https://doi.org/10.1158/1940-6207.22533122.v1","pdf_url":null,"source":null,"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"acceptedVersion","is_accepted":true,"is_published":false,"raw_source_name":"American Association for Cancer Research","raw_type":"posted-content"},"volume":null,"type":"supplementary-materials","is_traditional":false,"indexed_in":["crossref"],"open_access":{"is_oa":true,"oa_status":"gold","oa_url":"https://doi.org/10.1158/1940-6207.22533122.v1","any_repository_has_fulltext":null},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5039329425","display_name":"Timothy J. Zumwalt","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Timothy J. Zumwalt","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5089070170","display_name":"Dominik Wodarz","orcid":"https://orcid.org/0000-0002-8017-3707","observed_orcids":["https://orcid.org/0000-0002-8017-3707"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Dominik Wodarz","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5053552440","display_name":"Natalia L. Komarova","orcid":"https://orcid.org/0000-0003-4876-0343","observed_orcids":["https://orcid.org/0000-0003-4876-0343"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Natalia L. Komarova","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5080837446","display_name":"Shusuke Toden","orcid":"https://orcid.org/0000-0002-3270-3611","observed_orcids":["https://orcid.org/0000-0002-3270-3611"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Shusuke Toden","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5101760713","display_name":"Jacob Turner","orcid":"https://orcid.org/0000-0003-3275-6913","observed_orcids":["https://orcid.org/0000-0003-3275-6913"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Jacob Turner","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5071604865","display_name":"Jacob Cardenas","orcid":"https://orcid.org/0000-0003-3290-6053","observed_orcids":["https://orcid.org/0000-0003-3290-6053"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Jacob Cardenas","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5029949140","display_name":"John Burn","orcid":"https://orcid.org/0000-0002-9823-2322","observed_orcids":["https://orcid.org/0000-0002-9823-2322"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"John Burn","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5068835941","display_name":"Andrew Tan Chan","orcid":"https://orcid.org/0000-0001-7284-6767","observed_orcids":["https://orcid.org/0000-0001-7284-6767","https://orcid.org/0000-0002-3662-5964","https://orcid.org/0000-0002-5436-4219"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Andrew T. Chan","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5084691563","display_name":"Clement Richard Boland","orcid":"https://orcid.org/0000-0002-8120-5088","observed_orcids":["https://orcid.org/0000-0002-8120-5088"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"C. Richard Boland","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"last","author":{"id":"https://openalex.org/A5101530683","display_name":"Ajay Goel","orcid":"https://orcid.org/0000-0003-1396-6341","observed_orcids":["https://orcid.org/0000-0003-1396-6341"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Ajay Goel","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]}],"institutions":[],"countries_distinct_count":0,"institutions_distinct_count":0,"corresponding_author_ids":[],"corresponding_institution_ids":[],"apc_list":null,"apc_paid":null,"fwci":null,"has_fulltext":false,"cited_by_count":0,"citation_normalized_percentile":null,"cited_by_percentile_year":null,"biblio":{"volume":null,"issue":null,"first_page":null,"last_page":null},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T11067","display_name":"Colorectal Cancer Treatments and Studies","score":0.4684999883174896,"subfield":{"id":"https://openalex.org/subfields/2730","display_name":"Oncology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T11067","display_name":"Colorectal Cancer Treatments and Studies","score":0.4684999883174896,"subfield":{"id":"https://openalex.org/subfields/2730","display_name":"Oncology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10678","display_name":"Inflammatory mediators and NSAID effects","score":0.27469998598098755,"subfield":{"id":"https://openalex.org/subfields/2736","display_name":"Pharmacology (medical)"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10952","display_name":"PI3K/AKT/mTOR signaling in cancer","score":0.12150000035762787,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/aspirin","display_name":"aspirin","score":0.9909999966621399},{"id":"https://openalex.org/keywords/chemoprevention","display_name":"chemoprevention","score":0.9909999966621399},{"id":"https://openalex.org/keywords/pik3ca-mutation","display_name":"PIK3CA mutation","score":0.9710000157356262},{"id":"https://openalex.org/keywords/colorectal-cancer","display_name":"colorectal cancer","score":0.8849999904632568},{"id":"https://openalex.org/keywords/response-kinetics","display_name":"response kinetics","score":0.7139999866485596},{"id":"https://openalex.org/keywords/colorectal-cancer-cells","display_name":"colorectal cancer cells","score":0.7319999933242798},{"id":"https://openalex.org/keywords/rt-qpcr-primers","display_name":"qRT-PCR primers","score":0.8149999976158142}],"concepts":[{"id":"https://openalex.org/C2777628954","wikidata":"https://www.wikidata.org/wiki/Q18216","display_name":"Aspirin","level":2,"score":0.6936541795730591},{"id":"https://openalex.org/C526805850","wikidata":"https://www.wikidata.org/wiki/Q188874","display_name":"Colorectal cancer","level":3,"score":0.6846402883529663},{"id":"https://openalex.org/C148898269","wikidata":"https://www.wikidata.org/wiki/Q1108792","display_name":"Kinetics","level":2,"score":0.5356324315071106},{"id":"https://openalex.org/C502942594","wikidata":"https://www.wikidata.org/wiki/Q3421914","display_name":"Cancer research","level":1,"score":0.514674961566925},{"id":"https://openalex.org/C501734568","wikidata":"https://www.wikidata.org/wiki/Q42918","display_name":"Mutation","level":3,"score":0.4133340120315552},{"id":"https://openalex.org/C121608353","wikidata":"https://www.wikidata.org/wiki/Q12078","display_name":"Cancer","level":2,"score":0.37200087308883667},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.3672523498535156},{"id":"https://openalex.org/C185592680","wikidata":"https://www.wikidata.org/wiki/Q2329","display_name":"Chemistry","level":0,"score":0.33710402250289917},{"id":"https://openalex.org/C143998085","wikidata":"https://www.wikidata.org/wiki/Q162555","display_name":"Oncology","level":1,"score":0.33208149671554565},{"id":"https://openalex.org/C153911025","wikidata":"https://www.wikidata.org/wiki/Q7202","display_name":"Molecular biology","level":1,"score":0.32045695185661316},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.31132811307907104},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.28949135541915894},{"id":"https://openalex.org/C54355233","wikidata":"https://www.wikidata.org/wiki/Q7162","display_name":"Genetics","level":1,"score":0.2707017660140991},{"id":"https://openalex.org/C104317684","wikidata":"https://www.wikidata.org/wiki/Q7187","display_name":"Gene","level":2,"score":0.15949615836143494},{"id":"https://openalex.org/C121332964","wikidata":"https://www.wikidata.org/wiki/Q413","display_name":"Physics","level":0,"score":0.07570546865463257},{"id":"https://openalex.org/C62520636","wikidata":"https://www.wikidata.org/wiki/Q944","display_name":"Quantum mechanics","level":1,"score":0.0}],"mesh":[],"locations_count":1,"locations":[{"id":"doi:10.1158/1940-6207.22533122.v1","doi":"https://doi.org/10.1158/1940-6207.22533122.v1","is_oa":true,"landing_page_url":"https://doi.org/10.1158/1940-6207.22533122.v1","pdf_url":null,"source":null,"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"acceptedVersion","is_accepted":true,"is_published":false,"raw_source_name":"American Association for Cancer Research","raw_type":"posted-content"}],"best_oa_location":{"id":"doi:10.1158/1940-6207.22533122.v1","doi":"https://doi.org/10.1158/1940-6207.22533122.v1","is_oa":true,"landing_page_url":"https://doi.org/10.1158/1940-6207.22533122.v1","pdf_url":null,"source":null,"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"acceptedVersion","is_accepted":true,"is_published":false,"raw_source_name":"American Association for Cancer Research","raw_type":"posted-content"},"sustainable_development_goals":[{"score":0.9537000060081482,"id":"https://metadata.un.org/sdg/3","display_name":"Good health and well-being"}],"study_designs":[],"awards":[],"funders":[],"has_content":{"grobid_xml":false,"pdf":false},"content_urls":null,"referenced_works_count":0,"referenced_works":[],"related_works":["https://openalex.org/W4392722293","https://openalex.org/W2585220181","https://openalex.org/W4246921988","https://openalex.org/W3024699567","https://openalex.org/W2066304597","https://openalex.org/W7144811595","https://openalex.org/W3003762618","https://openalex.org/W2068444638","https://openalex.org/W2940373975","https://openalex.org/W2944346097"],"abstract_inverted_index":{"SYBR":[0],"green":[1],"qRT-PCR":[2],"Primers":[3],".":[4]},"counts_by_year":[],"updated_date":"2026-11-05T12:25:35.769452","created_date":"2023-04-07T00:00:00"}