{"id":"https://openalex.org/W4362630320","doi":"https://doi.org/10.1158/2767-9764.22545153.v1","title":"Supplementary Figure S12 from Tumor Cell\u2013Autonomous SHP2 Contributes to Immune Suppression in Metastatic Breast Cancer","display_name":"Supplementary Figure S12 from Tumor Cell\u2013Autonomous SHP2 Contributes to Immune Suppression in Metastatic Breast Cancer","publication_year":2023,"publication_date":"2023-04-04","ids":{"openalex":"https://openalex.org/W4362630320","doi":"https://doi.org/10.1158/2767-9764.22545153.v1"},"language":"en","primary_location":{"id":"doi:10.1158/2767-9764.22545153.v1","doi":"https://doi.org/10.1158/2767-9764.22545153.v1","is_oa":true,"landing_page_url":"https://doi.org/10.1158/2767-9764.22545153.v1","pdf_url":null,"source":null,"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"acceptedVersion","is_accepted":true,"is_published":false,"raw_source_name":"American Association for Cancer Research","raw_type":"posted-content"},"volume":null,"type":"supplementary-materials","indexed_in":["crossref"],"open_access":{"is_oa":true,"oa_status":"gold","oa_url":"https://doi.org/10.1158/2767-9764.22545153.v1","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5100719807","display_name":"Hao Chen","orcid":"https://orcid.org/0000-0002-2070-5062","observed_orcids":["https://orcid.org/0000-0002-2070-5062"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Hao Chen","raw_affiliation_strings":[],"raw_orcid":"https://orcid.org/0000-0002-2070-5062","affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5090084983","display_name":"Gregory M. Cresswell","orcid":"https://orcid.org/0000-0003-0616-0366","observed_orcids":["https://orcid.org/0000-0003-0616-0366"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Gregory M. Cresswell","raw_affiliation_strings":[],"raw_orcid":"https://orcid.org/0000-0003-0616-0366","affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5049067553","display_name":"Sarah Libring","orcid":"https://orcid.org/0000-0001-8336-5862","observed_orcids":["https://orcid.org/0000-0001-8336-5862"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Sarah Libring","raw_affiliation_strings":[],"raw_orcid":"https://orcid.org/0000-0001-8336-5862","affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5020198701","display_name":"Mitchell G. Ayers","orcid":"https://orcid.org/0000-0003-4049-9013","observed_orcids":["https://orcid.org/0000-0003-4049-9013"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Mitchell G. Ayers","raw_affiliation_strings":[],"raw_orcid":"https://orcid.org/0000-0003-4049-9013","affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5038545670","display_name":"Jinmin Miao","orcid":"https://orcid.org/0000-0001-7471-0847","observed_orcids":["https://orcid.org/0000-0001-7471-0847"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Jinmin Miao","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5101802542","display_name":"Zhong\u2010Yin Zhang","orcid":"https://orcid.org/0000-0001-5527-7910","observed_orcids":["https://orcid.org/0000-0001-5527-7910"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Zhong-Yin Zhang","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5054791772","display_name":"Luis Solorio","orcid":"https://orcid.org/0000-0003-0135-8728","observed_orcids":["https://orcid.org/0000-0003-0135-8728"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Luis Solorio","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5081030515","display_name":"Timothy L. Ratliff","orcid":"https://orcid.org/0000-0003-4221-5416","observed_orcids":["https://orcid.org/0000-0003-4221-5416"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Timothy L. Ratliff","raw_affiliation_strings":[],"raw_orcid":"https://orcid.org/0000-0003-4221-5416","affiliations":[]},{"author_position":"last","author":{"id":"https://openalex.org/A5090843213","display_name":"Michael K. Wendt","orcid":"https://orcid.org/0000-0002-3665-7413","observed_orcids":["https://orcid.org/0000-0002-3665-7413"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Michael K. Wendt","raw_affiliation_strings":[],"raw_orcid":"https://orcid.org/0000-0002-3665-7413","affiliations":[]}],"institutions":[],"countries_distinct_count":0,"institutions_distinct_count":0,"corresponding_author_ids":[],"corresponding_institution_ids":[],"apc_list":null,"apc_paid":null,"fwci":null,"has_fulltext":false,"cited_by_count":0,"citation_normalized_percentile":null,"cited_by_percentile_year":null,"biblio":{"volume":null,"issue":null,"first_page":null,"last_page":null},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T12104","display_name":"Protein Tyrosine Phosphatases","score":0.9779999852180481,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T12104","display_name":"Protein Tyrosine Phosphatases","score":0.9779999852180481,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10158","display_name":"Cancer Immunotherapy and Biomarkers","score":0.010900000110268593,"subfield":{"id":"https://openalex.org/subfields/2730","display_name":"Oncology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T11313","display_name":"Immune cells in cancer","score":0.0052999998442828655,"subfield":{"id":"https://openalex.org/subfields/2403","display_name":"Immunology"},"field":{"id":"https://openalex.org/fields/24","display_name":"Immunology and Microbiology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/shp2","display_name":"SHP2","score":0.8880000114440918},{"id":"https://openalex.org/keywords/tumor-immunosuppression","display_name":"tumor immunosuppression","score":0.6759999990463257},{"id":"https://openalex.org/keywords/metastatic-breast-cancer","display_name":"metastatic breast cancer","score":0.8600000143051147},{"id":"https://openalex.org/keywords/regulatory-t-cells","display_name":"regulatory T cells","score":0.9480000138282776},{"id":"https://openalex.org/keywords/tumor-associated-macrophages","display_name":"tumor-associated macrophages","score":0.9750000238418579},{"id":"https://openalex.org/keywords/tumor-microenvironment","display_name":"tumor microenvironment","score":0.6499999761581421}],"concepts":[{"id":"https://openalex.org/C2775930923","wikidata":"https://www.wikidata.org/wiki/Q12859063","display_name":"Metastatic breast cancer","level":4,"score":0.6267796158790588},{"id":"https://openalex.org/C8891405","wikidata":"https://www.wikidata.org/wiki/Q1059","display_name":"Immune system","level":2,"score":0.6112208366394043},{"id":"https://openalex.org/C530470458","wikidata":"https://www.wikidata.org/wiki/Q128581","display_name":"Breast cancer","level":3,"score":0.574834406375885},{"id":"https://openalex.org/C121608353","wikidata":"https://www.wikidata.org/wiki/Q12078","display_name":"Cancer","level":2,"score":0.5576980113983154},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.40399664640426636},{"id":"https://openalex.org/C143998085","wikidata":"https://www.wikidata.org/wiki/Q162555","display_name":"Oncology","level":1,"score":0.3912033438682556},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.2888849973678589},{"id":"https://openalex.org/C203014093","wikidata":"https://www.wikidata.org/wiki/Q101929","display_name":"Immunology","level":1,"score":0.16064181923866272}],"mesh":[],"locations_count":2,"locations":[{"id":"doi:10.1158/2767-9764.22545153.v1","doi":"https://doi.org/10.1158/2767-9764.22545153.v1","is_oa":true,"landing_page_url":"https://doi.org/10.1158/2767-9764.22545153.v1","pdf_url":null,"source":null,"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"acceptedVersion","is_accepted":true,"is_published":false,"raw_source_name":"American Association for Cancer Research","raw_type":"posted-content"},{"id":"pmh:oai:figshare.com:article/22545153","doi":null,"is_oa":true,"landing_page_url":"https://figshare.com/articles/journal_contribution/Supplementary_Figure_S12_from_Tumor_Cell_Autonomous_SHP2_Contributes_to_Immune_Suppression_in_Metastatic_Breast_Cancer/22545153","pdf_url":null,"source":{"id":"https://openalex.org/S4377196282","display_name":"Figshare","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I4210132348","host_organization_name":"Figshare (United Kingdom)","host_organization_lineage":["https://openalex.org/I4210132348"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"","raw_type":"Text"}],"best_oa_location":{"id":"doi:10.1158/2767-9764.22545153.v1","doi":"https://doi.org/10.1158/2767-9764.22545153.v1","is_oa":true,"landing_page_url":"https://doi.org/10.1158/2767-9764.22545153.v1","pdf_url":null,"source":null,"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"acceptedVersion","is_accepted":true,"is_published":false,"raw_source_name":"American Association for Cancer Research","raw_type":"posted-content"},"sustainable_development_goals":[{"id":"https://metadata.un.org/sdg/3","display_name":"Good health and well-being","score":0.9537000060081482}],"study_designs":[],"awards":[],"funders":[],"has_content":{"grobid_xml":false,"pdf":false},"content_urls":null,"referenced_works_count":0,"referenced_works":[],"related_works":["https://openalex.org/W4362525329","https://openalex.org/W4294011762","https://openalex.org/W6889160373","https://openalex.org/W1514955680","https://openalex.org/W4361842325","https://openalex.org/W3021048814","https://openalex.org/W4394824570","https://openalex.org/W2044267375","https://openalex.org/W2803801423","https://openalex.org/W3013404290"],"abstract_inverted_index":{"Analyses":[0],"of":[1],"Tregs":[2],"and":[3],"macrophage":[4],"scores":[5],"in":[6],"clinical":[7],"datasets":[8],"with":[9],"respect":[10],"to":[11],"SHP2":[12],"phosphorylation.":[13]},"counts_by_year":[],"updated_date":"2026-10-16T09:59:22.235173","created_date":"2023-04-07T00:00:00"}