{"id":"https://openalex.org/W4362619935","doi":"https://doi.org/10.1158/2767-9764.22545162","title":"Supplementary Figure S1 from Tumor Cell\u2013Autonomous SHP2 Contributes to Immune Suppression in Metastatic Breast Cancer","display_name":"Supplementary Figure S1 from Tumor Cell\u2013Autonomous SHP2 Contributes to Immune Suppression in Metastatic Breast Cancer","publication_year":2023,"publication_date":"2023-04-04","ids":{"openalex":"https://openalex.org/W4362619935","doi":"https://doi.org/10.1158/2767-9764.22545162"},"language":"en","primary_location":{"id":"doi:10.1158/2767-9764.22545162","doi":"https://doi.org/10.1158/2767-9764.22545162","is_oa":true,"landing_page_url":"https://doi.org/10.1158/2767-9764.22545162","pdf_url":"https://aacr.figshare.com/articles/journal_contribution/Supplementary_Figure_S1_from_Tumor_Cell_Autonomous_SHP2_Contributes_to_Immune_Suppression_in_Metastatic_Breast_Cancer/22545162/1/files/40008591.pdf","source":null,"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"acceptedVersion","is_accepted":true,"is_published":false,"raw_source_name":"American Association for Cancer Research","raw_type":"posted-content"},"volume":null,"type":"supplementary-materials","indexed_in":["crossref"],"open_access":{"is_oa":true,"oa_status":"gold","oa_url":"https://aacr.figshare.com/articles/journal_contribution/Supplementary_Figure_S1_from_Tumor_Cell_Autonomous_SHP2_Contributes_to_Immune_Suppression_in_Metastatic_Breast_Cancer/22545162/1/files/40008591.pdf","any_repository_has_fulltext":null},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5100719807","display_name":"Hao Chen","orcid":"https://orcid.org/0000-0002-2070-5062","observed_orcids":["https://orcid.org/0000-0002-2070-5062"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Hao Chen","raw_affiliation_strings":[],"raw_orcid":"https://orcid.org/0000-0002-2070-5062","affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5090084983","display_name":"Gregory M. Cresswell","orcid":"https://orcid.org/0000-0003-0616-0366","observed_orcids":["https://orcid.org/0000-0003-0616-0366"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Gregory M. Cresswell","raw_affiliation_strings":[],"raw_orcid":"https://orcid.org/0000-0003-0616-0366","affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5049067553","display_name":"Sarah Libring","orcid":"https://orcid.org/0000-0001-8336-5862","observed_orcids":["https://orcid.org/0000-0001-8336-5862"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Sarah Libring","raw_affiliation_strings":[],"raw_orcid":"https://orcid.org/0000-0001-8336-5862","affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5020198701","display_name":"Mitchell G. Ayers","orcid":"https://orcid.org/0000-0003-4049-9013","observed_orcids":["https://orcid.org/0000-0003-4049-9013"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Mitchell G. Ayers","raw_affiliation_strings":[],"raw_orcid":"https://orcid.org/0000-0003-4049-9013","affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5038545670","display_name":"Jinmin Miao","orcid":"https://orcid.org/0000-0001-7471-0847","observed_orcids":["https://orcid.org/0000-0001-7471-0847"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Jinmin Miao","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5101802542","display_name":"Zhong\u2010Yin Zhang","orcid":"https://orcid.org/0000-0001-5527-7910","observed_orcids":["https://orcid.org/0000-0001-5527-7910"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Zhong-Yin Zhang","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5054791772","display_name":"Luis Solorio","orcid":"https://orcid.org/0000-0003-0135-8728","observed_orcids":["https://orcid.org/0000-0003-0135-8728"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Luis Solorio","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5081030515","display_name":"Timothy L. Ratliff","orcid":"https://orcid.org/0000-0003-4221-5416","observed_orcids":["https://orcid.org/0000-0003-4221-5416"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Timothy L. Ratliff","raw_affiliation_strings":[],"raw_orcid":"https://orcid.org/0000-0003-4221-5416","affiliations":[]},{"author_position":"last","author":{"id":"https://openalex.org/A5090843213","display_name":"Michael K. Wendt","orcid":"https://orcid.org/0000-0002-3665-7413","observed_orcids":["https://orcid.org/0000-0002-3665-7413"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Michael K. Wendt","raw_affiliation_strings":[],"raw_orcid":"https://orcid.org/0000-0002-3665-7413","affiliations":[]}],"institutions":[],"countries_distinct_count":0,"institutions_distinct_count":0,"corresponding_author_ids":[],"corresponding_institution_ids":[],"apc_list":null,"apc_paid":null,"fwci":null,"has_fulltext":false,"cited_by_count":0,"citation_normalized_percentile":null,"cited_by_percentile_year":null,"biblio":{"volume":null,"issue":null,"first_page":null,"last_page":null},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T12104","display_name":"Protein Tyrosine Phosphatases","score":0.975600004196167,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T12104","display_name":"Protein Tyrosine Phosphatases","score":0.975600004196167,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10158","display_name":"Cancer Immunotherapy and Biomarkers","score":0.020999999716877937,"subfield":{"id":"https://openalex.org/subfields/2730","display_name":"Oncology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T11313","display_name":"Immune cells in cancer","score":0.0006000000284984708,"subfield":{"id":"https://openalex.org/subfields/2403","display_name":"Immunology"},"field":{"id":"https://openalex.org/fields/24","display_name":"Immunology and Microbiology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/shp2","display_name":"SHP2","score":0.9649999737739563},{"id":"https://openalex.org/keywords/shp099","display_name":"SHP099","score":0.9079999923706055},{"id":"https://openalex.org/keywords/pd-l1","display_name":"PD-L1","score":0.7009999752044678},{"id":"https://openalex.org/keywords/immune-checkpoint-blockade","display_name":"immune checkpoint blockade","score":0.6579999923706055},{"id":"https://openalex.org/keywords/tumor-immunosuppression","display_name":"tumor immunosuppression","score":0.8349999785423279},{"id":"https://openalex.org/keywords/metastatic-breast-cancer","display_name":"metastatic breast cancer","score":0.9860000014305115},{"id":"https://openalex.org/keywords/lung-metastasis","display_name":"lung metastasis","score":0.8949999809265137},{"id":"https://openalex.org/keywords/combination-therapy","display_name":"combination therapy","score":0.5550000071525574}],"concepts":[{"id":"https://openalex.org/C8891405","wikidata":"https://www.wikidata.org/wiki/Q1059","display_name":"Immune system","level":2,"score":0.650344729423523},{"id":"https://openalex.org/C530470458","wikidata":"https://www.wikidata.org/wiki/Q128581","display_name":"Breast cancer","level":3,"score":0.6379764676094055},{"id":"https://openalex.org/C502942594","wikidata":"https://www.wikidata.org/wiki/Q3421914","display_name":"Cancer research","level":1,"score":0.5917725563049316},{"id":"https://openalex.org/C2775930923","wikidata":"https://www.wikidata.org/wiki/Q12859063","display_name":"Metastatic breast cancer","level":4,"score":0.5855305194854736},{"id":"https://openalex.org/C207001950","wikidata":"https://www.wikidata.org/wiki/Q141124","display_name":"In vivo","level":2,"score":0.5060257315635681},{"id":"https://openalex.org/C121608353","wikidata":"https://www.wikidata.org/wiki/Q12078","display_name":"Cancer","level":2,"score":0.4422970116138458},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.4341731071472168},{"id":"https://openalex.org/C143998085","wikidata":"https://www.wikidata.org/wiki/Q162555","display_name":"Oncology","level":1,"score":0.40432941913604736},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.4026075005531311},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.27673864364624023},{"id":"https://openalex.org/C203014093","wikidata":"https://www.wikidata.org/wiki/Q101929","display_name":"Immunology","level":1,"score":0.22251001000404358},{"id":"https://openalex.org/C54355233","wikidata":"https://www.wikidata.org/wiki/Q7162","display_name":"Genetics","level":1,"score":0.05275118350982666}],"mesh":[],"locations_count":1,"locations":[{"id":"doi:10.1158/2767-9764.22545162","doi":"https://doi.org/10.1158/2767-9764.22545162","is_oa":true,"landing_page_url":"https://doi.org/10.1158/2767-9764.22545162","pdf_url":"https://aacr.figshare.com/articles/journal_contribution/Supplementary_Figure_S1_from_Tumor_Cell_Autonomous_SHP2_Contributes_to_Immune_Suppression_in_Metastatic_Breast_Cancer/22545162/1/files/40008591.pdf","source":null,"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"acceptedVersion","is_accepted":true,"is_published":false,"raw_source_name":"American Association for Cancer Research","raw_type":"posted-content"}],"best_oa_location":{"id":"doi:10.1158/2767-9764.22545162","doi":"https://doi.org/10.1158/2767-9764.22545162","is_oa":true,"landing_page_url":"https://doi.org/10.1158/2767-9764.22545162","pdf_url":"https://aacr.figshare.com/articles/journal_contribution/Supplementary_Figure_S1_from_Tumor_Cell_Autonomous_SHP2_Contributes_to_Immune_Suppression_in_Metastatic_Breast_Cancer/22545162/1/files/40008591.pdf","source":null,"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"acceptedVersion","is_accepted":true,"is_published":false,"raw_source_name":"American Association for Cancer Research","raw_type":"posted-content"},"sustainable_development_goals":[{"score":0.9476000070571899,"id":"https://metadata.un.org/sdg/3","display_name":"Good health and well-being"}],"study_designs":[],"awards":[],"funders":[],"has_content":{"pdf":true,"grobid_xml":true},"content_urls":{"pdf":"https://content.openalex.org/works/W4362619935.pdf","grobid_xml":"https://content.openalex.org/works/W4362619935.grobid-xml"},"referenced_works_count":0,"referenced_works":[],"related_works":["https://openalex.org/W4362525329","https://openalex.org/W4294011762","https://openalex.org/W2891517856","https://openalex.org/W2755899253","https://openalex.org/W3207356559","https://openalex.org/W4282914015","https://openalex.org/W2236485872","https://openalex.org/W6889160373","https://openalex.org/W4236314118","https://openalex.org/W4392853945"],"abstract_inverted_index":{"Combination":[0],"of":[1],"SHP099":[2],"and":[3],"\u03b1-PD-L1":[4],"delays":[5],"D2.A1":[6],"pulmonary":[7],"growth":[8],"in":[9],"vivo":[10]},"counts_by_year":[],"updated_date":"2026-10-16T09:59:22.235173","created_date":"2023-04-07T00:00:00"}