{"id":"https://openalex.org/W4362614869","doi":"https://doi.org/10.1158/1535-7163.22523653","title":"Supplementary Figure from Luxeptinib (CG-806) Targets FLT3 and Clusters of Kinases Operative in Acute Myeloid Leukemia","display_name":"Supplementary Figure from Luxeptinib (CG-806) Targets FLT3 and Clusters of Kinases Operative in Acute Myeloid Leukemia","publication_year":2023,"publication_date":"2023-04-03","ids":{"openalex":"https://openalex.org/W4362614869","doi":"https://doi.org/10.1158/1535-7163.22523653"},"language":"en","primary_location":{"id":"doi:10.1158/1535-7163.22523653","doi":"https://doi.org/10.1158/1535-7163.22523653","is_oa":true,"landing_page_url":"https://doi.org/10.1158/1535-7163.22523653","pdf_url":null,"source":null,"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"acceptedVersion","is_accepted":true,"is_published":false,"raw_source_name":"American Association for Cancer Research","raw_type":"posted-content"},"volume":null,"type":"supplementary-materials","indexed_in":["crossref"],"open_access":{"is_oa":true,"oa_status":"gold","oa_url":"https://doi.org/10.1158/1535-7163.22523653","any_repository_has_fulltext":null},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5024503165","display_name":"William G. Rice","orcid":"https://orcid.org/0000-0001-5705-9474","observed_orcids":["https://orcid.org/0000-0001-5705-9474"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"William G. Rice","raw_affiliation_strings":[],"raw_orcid":"https://orcid.org/0000-0001-5705-9474","affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5024148760","display_name":"Stephen B. Howell","orcid":"https://orcid.org/0000-0002-0877-8226","observed_orcids":["https://orcid.org/0000-0002-0877-8226"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Stephen B. Howell","raw_affiliation_strings":[],"raw_orcid":"https://orcid.org/0000-0002-0877-8226","affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5048303911","display_name":"Hongying Zhang","orcid":"https://orcid.org/0000-0003-4517-8825","observed_orcids":["https://orcid.org/0000-0003-4517-8825"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Hongying Zhang","raw_affiliation_strings":[],"raw_orcid":"https://orcid.org/0000-0003-4517-8825","affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5083309139","display_name":"Nasrin Rastgoo","orcid":"https://orcid.org/0000-0002-9320-8841","observed_orcids":["https://orcid.org/0000-0002-9320-8841"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Nasrin Rastgoo","raw_affiliation_strings":[],"raw_orcid":"https://orcid.org/0000-0002-9320-8841","affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5014765656","display_name":"Andrea Local","orcid":"https://orcid.org/0000-0003-2963-0607","observed_orcids":["https://orcid.org/0000-0003-2963-0607"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Andrea Local","raw_affiliation_strings":[],"raw_orcid":"https://orcid.org/0000-0003-2963-0607","affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5075070858","display_name":"Stephen E. Kurtz","orcid":"https://orcid.org/0000-0003-4762-389X","observed_orcids":["https://orcid.org/0000-0003-4762-389X"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Stephen E. Kurtz","raw_affiliation_strings":[],"raw_orcid":"https://orcid.org/0000-0003-4762-389X","affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5075328633","display_name":"Pierrette Lo","orcid":"https://orcid.org/0000-0001-9221-4222","observed_orcids":["https://orcid.org/0000-0001-9221-4222"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Pierrette Lo","raw_affiliation_strings":[],"raw_orcid":"https://orcid.org/0000-0001-9221-4222","affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5061516412","display_name":"Daniel Bottomly","orcid":"https://orcid.org/0000-0001-7191-0990","observed_orcids":["https://orcid.org/0000-0001-7191-0990"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Daniel Bottomly","raw_affiliation_strings":[],"raw_orcid":"https://orcid.org/0000-0001-7191-0990","affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5010834454","display_name":"Beth Wilmot","orcid":"https://orcid.org/0000-0003-3579-3592","observed_orcids":["https://orcid.org/0000-0003-3579-3592"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Beth Wilmot","raw_affiliation_strings":[],"raw_orcid":"https://orcid.org/0000-0003-3579-3592","affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5066373576","display_name":"Shannon K. McWeeney","orcid":"https://orcid.org/0000-0001-8333-6607","observed_orcids":["https://orcid.org/0000-0001-8333-6607"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Shannon K. McWeeney","raw_affiliation_strings":[],"raw_orcid":"https://orcid.org/0000-0001-8333-6607","affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5125591963","display_name":"Brian J. Druker","orcid":"https://orcid.org/0000-0001-8331-8206","observed_orcids":["https://orcid.org/0000-0001-8331-8206"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Brian J. Druker","raw_affiliation_strings":[],"raw_orcid":"https://orcid.org/0000-0001-8331-8206","affiliations":[]},{"author_position":"last","author":{"id":"https://openalex.org/A5134831711","display_name":"Jeffrey W Tyner","orcid":"https://orcid.org/0000-0002-2133-0960","observed_orcids":["https://orcid.org/0000-0002-2133-0960"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Jeffrey W. Tyner","raw_affiliation_strings":[],"raw_orcid":"https://orcid.org/0000-0002-2133-0960","affiliations":[]}],"institutions":[],"countries_distinct_count":0,"institutions_distinct_count":0,"corresponding_author_ids":[],"corresponding_institution_ids":[],"apc_list":null,"apc_paid":null,"fwci":null,"has_fulltext":false,"cited_by_count":0,"citation_normalized_percentile":null,"cited_by_percentile_year":null,"biblio":{"volume":null,"issue":null,"first_page":null,"last_page":null},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10309","display_name":"Acute Myeloid Leukemia Research","score":0.9994999766349792,"subfield":{"id":"https://openalex.org/subfields/2720","display_name":"Hematology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T10309","display_name":"Acute Myeloid Leukemia Research","score":0.9994999766349792,"subfield":{"id":"https://openalex.org/subfields/2720","display_name":"Hematology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T11559","display_name":"Retinoids in leukemia and cellular processes","score":9.999999747378752e-05,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T12104","display_name":"Protein Tyrosine Phosphatases","score":9.999999747378752e-05,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/flt3","display_name":"FLT3","score":0.843999981880188},{"id":"https://openalex.org/keywords/acute-myeloid-leukemia","display_name":"acute myeloid leukemia","score":0.9700000286102295},{"id":"https://openalex.org/keywords/kinase-inhibitors","display_name":"kinase inhibitors","score":0.5139999985694885},{"id":"https://openalex.org/keywords/targeted-therapy","display_name":"targeted therapy","score":0.7160000205039978}],"concepts":[{"id":"https://openalex.org/C2778729363","wikidata":"https://www.wikidata.org/wiki/Q11688946","display_name":"Myeloid leukemia","level":2,"score":0.8522312641143799},{"id":"https://openalex.org/C184235292","wikidata":"https://www.wikidata.org/wiki/Q421851","display_name":"Kinase","level":2,"score":0.6238561272621155},{"id":"https://openalex.org/C502942594","wikidata":"https://www.wikidata.org/wiki/Q3421914","display_name":"Cancer research","level":1,"score":0.4844817817211151},{"id":"https://openalex.org/C2779282312","wikidata":"https://www.wikidata.org/wiki/Q1956561","display_name":"Myeloid","level":2,"score":0.45210736989974976},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.41824179887771606},{"id":"https://openalex.org/C2778461978","wikidata":"https://www.wikidata.org/wiki/Q29496","display_name":"Leukemia","level":2,"score":0.41611596941947937},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.23082628846168518},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.21597781777381897},{"id":"https://openalex.org/C95444343","wikidata":"https://www.wikidata.org/wiki/Q7141","display_name":"Cell biology","level":1,"score":0.18059512972831726}],"mesh":[],"locations_count":1,"locations":[{"id":"doi:10.1158/1535-7163.22523653","doi":"https://doi.org/10.1158/1535-7163.22523653","is_oa":true,"landing_page_url":"https://doi.org/10.1158/1535-7163.22523653","pdf_url":null,"source":null,"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"acceptedVersion","is_accepted":true,"is_published":false,"raw_source_name":"American Association for Cancer Research","raw_type":"posted-content"}],"best_oa_location":{"id":"doi:10.1158/1535-7163.22523653","doi":"https://doi.org/10.1158/1535-7163.22523653","is_oa":true,"landing_page_url":"https://doi.org/10.1158/1535-7163.22523653","pdf_url":null,"source":null,"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"acceptedVersion","is_accepted":true,"is_published":false,"raw_source_name":"American Association for Cancer Research","raw_type":"posted-content"},"sustainable_development_goals":[{"display_name":"Good health and well-being","id":"https://metadata.un.org/sdg/3","score":0.6240000128746033}],"study_designs":[],"awards":[],"funders":[],"has_content":{"grobid_xml":false,"pdf":false},"content_urls":null,"referenced_works_count":0,"referenced_works":[],"related_works":["https://openalex.org/W4392700954","https://openalex.org/W4225282245","https://openalex.org/W3212366572","https://openalex.org/W4310159094","https://openalex.org/W4399693780","https://openalex.org/W4304845384","https://openalex.org/W2938682201","https://openalex.org/W2200839210","https://openalex.org/W2785196458","https://openalex.org/W3171021181"],"abstract_inverted_index":{"Supplementary":[0],"Figure":[1],"from":[2],"Luxeptinib":[3],"(CG-806)":[4],"Targets":[5],"FLT3":[6],"and":[7],"Clusters":[8],"of":[9],"Kinases":[10],"Operative":[11],"in":[12],"Acute":[13],"Myeloid":[14],"Leukemia":[15]},"counts_by_year":[],"updated_date":"2026-10-16T09:59:22.235173","created_date":"2023-04-07T00:00:00"}