{"id":"https://openalex.org/W4362611542","doi":"https://doi.org/10.1158/1535-7163.22500873","title":"Supplementary Figure 2 from An Autocrine Loop between TGF-\u03b21 and the Transcription Factor Brachyury Controls the Transition of Human Carcinoma Cells into a Mesenchymal Phenotype","display_name":"Supplementary Figure 2 from An Autocrine Loop between TGF-\u03b21 and the Transcription Factor Brachyury Controls the Transition of Human Carcinoma Cells into a Mesenchymal Phenotype","publication_year":2023,"publication_date":"2023-04-03","ids":{"openalex":"https://openalex.org/W4362611542","doi":"https://doi.org/10.1158/1535-7163.22500873"},"language":"en","primary_location":{"id":"doi:10.1158/1535-7163.22500873","doi":"https://doi.org/10.1158/1535-7163.22500873","is_oa":true,"landing_page_url":"https://doi.org/10.1158/1535-7163.22500873","pdf_url":"https://aacr.figshare.com/articles/journal_contribution/Supplementary_Figure_2_from_An_Autocrine_Loop_between_TGF-_1_and_the_Transcription_Factor_Brachyury_Controls_the_Transition_of_Human_Carcinoma_Cells_into_a_Mesenchymal_Phenotype/22500873/1/files/39960150.pdf","source":null,"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"acceptedVersion","is_accepted":true,"is_published":false,"raw_source_name":"American Association for Cancer Research","raw_type":"posted-content"},"volume":null,"type":"supplementary-materials","is_traditional":false,"indexed_in":["crossref"],"open_access":{"is_oa":true,"oa_status":"gold","oa_url":"https://aacr.figshare.com/articles/journal_contribution/Supplementary_Figure_2_from_An_Autocrine_Loop_between_TGF-_1_and_the_Transcription_Factor_Brachyury_Controls_the_Transition_of_Human_Carcinoma_Cells_into_a_Mesenchymal_Phenotype/22500873/1/files/39960150.pdf","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5062766083","display_name":"Cecilia A. Larocca","orcid":"https://orcid.org/0000-0002-6756-261X","observed_orcids":["https://orcid.org/0000-0002-6756-261X"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Cecilia Larocca","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":null,"display_name":"Joseph R. Cohen","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Joseph R. Cohen","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5103538909","display_name":"Romaine Ingrid Fernando","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Romaine I. Fernando","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":null,"display_name":"Bruce Huang","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Bruce Huang","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5070191245","display_name":"Duane H. Hamilton","orcid":"https://orcid.org/0000-0002-9730-8209","observed_orcids":["https://orcid.org/0000-0002-9730-8209"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Duane H. Hamilton","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"last","author":{"id":"https://openalex.org/A5081826448","display_name":"Claudia Palena","orcid":"https://orcid.org/0000-0002-0445-4486","observed_orcids":["https://orcid.org/0000-0002-0445-4486"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Claudia Palena","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]}],"institutions":[],"countries_distinct_count":0,"institutions_distinct_count":0,"corresponding_author_ids":[],"corresponding_institution_ids":[],"apc_list":null,"apc_paid":null,"fwci":null,"has_fulltext":true,"cited_by_count":0,"citation_normalized_percentile":null,"cited_by_percentile_year":null,"biblio":{"volume":null,"issue":null,"first_page":null,"last_page":null},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T11501","display_name":"TGF-\u03b2 signaling in diseases","score":0.7886000275611877,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T11501","display_name":"TGF-\u03b2 signaling in diseases","score":0.7886000275611877,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10336","display_name":"Cancer Cells and Metastasis","score":0.19900000095367432,"subfield":{"id":"https://openalex.org/subfields/2730","display_name":"Oncology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T13437","display_name":"Mechanisms of cancer metastasis","score":0.0024999999441206455,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/tgf-beta1","display_name":"TGF-\u03b21","score":0.949999988079071},{"id":"https://openalex.org/keywords/brachyury","display_name":"Brachyury","score":0.9570000171661377},{"id":"https://openalex.org/keywords/autocrine-loop","display_name":"autocrine loop","score":0.7850000262260437},{"id":"https://openalex.org/keywords/mesenchymal-phenotype","display_name":"mesenchymal phenotype","score":0.8840000033378601},{"id":"https://openalex.org/keywords/colon-cancer","display_name":"colon cancer","score":0.6830000281333923},{"id":"https://openalex.org/keywords/sd-208","display_name":"SD-208","score":0.9850000143051147},{"id":"https://openalex.org/keywords/transcription-factors","display_name":"transcription factors","score":0.6869999766349792},{"id":"https://openalex.org/keywords/epithelial-mesenchymal-transition","display_name":"epithelial-mesenchymal transition","score":0.8650000095367432}],"concepts":[{"id":"https://openalex.org/C46122727","wikidata":"https://www.wikidata.org/wiki/Q14885879","display_name":"Brachyury","level":5,"score":0.9110653400421143},{"id":"https://openalex.org/C128240485","wikidata":"https://www.wikidata.org/wiki/Q786998","display_name":"Autocrine signalling","level":3,"score":0.6268244385719299},{"id":"https://openalex.org/C127716648","wikidata":"https://www.wikidata.org/wiki/Q104053","display_name":"Phenotype","level":3,"score":0.5906777381896973},{"id":"https://openalex.org/C118131993","wikidata":"https://www.wikidata.org/wiki/Q423671","display_name":"Transforming growth factor","level":2,"score":0.48348766565322876},{"id":"https://openalex.org/C86339819","wikidata":"https://www.wikidata.org/wiki/Q407384","display_name":"Transcription factor","level":3,"score":0.4822876751422882},{"id":"https://openalex.org/C2909082478","wikidata":"https://www.wikidata.org/wiki/Q33525","display_name":"Carcinoma Cell","level":3,"score":0.4379042387008667},{"id":"https://openalex.org/C198826908","wikidata":"https://www.wikidata.org/wiki/Q1922379","display_name":"Mesenchymal stem cell","level":2,"score":0.4215376377105713},{"id":"https://openalex.org/C95444343","wikidata":"https://www.wikidata.org/wiki/Q7141","display_name":"Cell biology","level":1,"score":0.3740513324737549},{"id":"https://openalex.org/C502942594","wikidata":"https://www.wikidata.org/wiki/Q3421914","display_name":"Cancer research","level":1,"score":0.35711658000946045},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.3498925566673279},{"id":"https://openalex.org/C54355233","wikidata":"https://www.wikidata.org/wiki/Q7162","display_name":"Genetics","level":1,"score":0.16937944293022156},{"id":"https://openalex.org/C81885089","wikidata":"https://www.wikidata.org/wiki/Q189082","display_name":"Cell culture","level":2,"score":0.15240219235420227},{"id":"https://openalex.org/C3020616263","wikidata":"https://www.wikidata.org/wiki/Q1216998","display_name":"Tumor cells","level":2,"score":0.14892196655273438},{"id":"https://openalex.org/C104317684","wikidata":"https://www.wikidata.org/wiki/Q7187","display_name":"Gene","level":2,"score":0.1130918562412262},{"id":"https://openalex.org/C2780915607","wikidata":"https://www.wikidata.org/wiki/Q323438","display_name":"Mesoderm","level":4,"score":0.06625509262084961},{"id":"https://openalex.org/C145103041","wikidata":"https://www.wikidata.org/wiki/Q1151519","display_name":"Embryonic stem cell","level":3,"score":0.0}],"mesh":[],"locations_count":3,"locations":[{"id":"doi:10.1158/1535-7163.22500873","doi":"https://doi.org/10.1158/1535-7163.22500873","is_oa":true,"landing_page_url":"https://doi.org/10.1158/1535-7163.22500873","pdf_url":"https://aacr.figshare.com/articles/journal_contribution/Supplementary_Figure_2_from_An_Autocrine_Loop_between_TGF-_1_and_the_Transcription_Factor_Brachyury_Controls_the_Transition_of_Human_Carcinoma_Cells_into_a_Mesenchymal_Phenotype/22500873/1/files/39960150.pdf","source":null,"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"acceptedVersion","is_accepted":true,"is_published":false,"raw_source_name":"American Association for Cancer Research","raw_type":"posted-content"},{"id":"doi:10.1158/1535-7163.22500873.v1","doi":"https://doi.org/10.1158/1535-7163.22500873.v1","is_oa":true,"landing_page_url":"https://doi.org/10.1158/1535-7163.22500873.v1","pdf_url":null,"source":null,"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"acceptedVersion","is_accepted":true,"is_published":false,"raw_source_name":"American Association for Cancer Research","raw_type":"posted-content"},{"id":"pmh:oai:figshare.com:article/22500873","doi":null,"is_oa":true,"landing_page_url":"https://figshare.com/articles/journal_contribution/Supplementary_Figure_2_from_An_Autocrine_Loop_between_TGF-_1_and_the_Transcription_Factor_Brachyury_Controls_the_Transition_of_Human_Carcinoma_Cells_into_a_Mesenchymal_Phenotype/22500873","pdf_url":null,"source":{"id":"https://openalex.org/S4377196282","display_name":"Figshare","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I4210132348","host_organization_name":"Figshare (United Kingdom)","host_organization_lineage":["https://openalex.org/I4210132348"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"","raw_type":"Text"}],"best_oa_location":{"id":"doi:10.1158/1535-7163.22500873","doi":"https://doi.org/10.1158/1535-7163.22500873","is_oa":true,"landing_page_url":"https://doi.org/10.1158/1535-7163.22500873","pdf_url":"https://aacr.figshare.com/articles/journal_contribution/Supplementary_Figure_2_from_An_Autocrine_Loop_between_TGF-_1_and_the_Transcription_Factor_Brachyury_Controls_the_Transition_of_Human_Carcinoma_Cells_into_a_Mesenchymal_Phenotype/22500873/1/files/39960150.pdf","source":null,"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"acceptedVersion","is_accepted":true,"is_published":false,"raw_source_name":"American Association for Cancer Research","raw_type":"posted-content"},"sustainable_development_goals":[{"id":"https://metadata.un.org/sdg/3","display_name":"Good health and well-being","score":0.766700029373169}],"study_designs":[],"awards":[],"funders":[],"has_content":{"grobid_xml":true,"pdf":true},"content_urls":{"pdf":"https://content.openalex.org/works/W4362611542.pdf","grobid_xml":"https://content.openalex.org/works/W4362611542.grobid-xml"},"referenced_works_count":0,"referenced_works":[],"related_works":["https://openalex.org/W4362495355","https://openalex.org/W2102124205","https://openalex.org/W3089693716","https://openalex.org/W2133580699","https://openalex.org/W2901221147","https://openalex.org/W6921021480","https://openalex.org/W1985947761","https://openalex.org/W4392679002","https://openalex.org/W3038243339","https://openalex.org/W6902315205"],"abstract_inverted_index":{"PDF":[0],"file":[1],"-":[2],"326K,":[3],"Treatment":[4],"with":[5],"SD-208":[6],"reverts":[7],"the":[8],"mesenchymal":[9],"phenotype":[10],"of":[11],"colon":[12],"carcinoma":[13],"cell":[14],"lines.":[15]},"counts_by_year":[],"updated_date":"2026-11-04T10:54:05.112534","created_date":"2023-04-06T00:00:00"}