{"id":"https://openalex.org/W4362609214","doi":"https://doi.org/10.1158/1535-7163.22498360","title":"Supplementary Figure 2 from Genome and Transcriptome Sequencing in Prospective Metastatic Triple-Negative Breast Cancer Uncovers Therapeutic Vulnerabilities","display_name":"Supplementary Figure 2 from Genome and Transcriptome Sequencing in Prospective Metastatic Triple-Negative Breast Cancer Uncovers Therapeutic Vulnerabilities","publication_year":2023,"publication_date":"2023-04-03","ids":{"openalex":"https://openalex.org/W4362609214","doi":"https://doi.org/10.1158/1535-7163.22498360"},"language":"en","primary_location":{"id":"doi:10.1158/1535-7163.22498360","doi":"https://doi.org/10.1158/1535-7163.22498360","is_oa":true,"landing_page_url":"http://dx.doi.org/10.1158/1535-7163.22498360","pdf_url":null,"source":null,"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"acceptedVersion","is_accepted":true,"is_published":false,"raw_source_name":"American Association for Cancer Research","raw_type":"posted-content"},"volume":null,"type":"supplementary-materials","indexed_in":["crossref"],"open_access":{"is_oa":true,"oa_status":"gold","oa_url":"http://dx.doi.org/10.1158/1535-7163.22498360","any_repository_has_fulltext":null},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5074460206","display_name":"David Wesley Craig","orcid":"https://orcid.org/0000-0003-2040-1955","observed_orcids":["https://orcid.org/0000-0003-2040-1955","https://orcid.org/0000-0003-0239-9441"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"David W. Craig","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5071432873","display_name":"Joyce O\u2019Shaughnessy","orcid":"https://orcid.org/0000-0001-6764-2807","observed_orcids":["https://orcid.org/0000-0001-6764-2807"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Joyce A. O'Shaughnessy","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5064611417","display_name":"Jeffrey Kiefer","orcid":"https://orcid.org/0000-0002-1238-3120","observed_orcids":["https://orcid.org/0000-0002-1238-3120"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Jeffrey A. Kiefer","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5090712632","display_name":"Jessica Aldrich","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Jessica Aldrich","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5041568284","display_name":"Shripad A. Sinari","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Shripad Sinari","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5071572579","display_name":"Tracy M. Moses","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Tracy M. Moses","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5102749207","display_name":"Shukmei Wong","orcid":"https://orcid.org/0000-0002-8551-2835","observed_orcids":["https://orcid.org/0000-0002-8551-2835"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Shukmei Wong","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":null,"display_name":"Jennifer Dinh","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Jennifer Dinh","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5020717809","display_name":"Alexis Christoforides","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Alexis Christoforides","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5042123072","display_name":"Joanne Lorraine Blum","orcid":"https://orcid.org/0000-0002-7951-6645","observed_orcids":["https://orcid.org/0000-0002-7951-6645"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Joanne L. Blum","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5074200635","display_name":"Cristi L. Aitelli","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Cristi L. Aitelli","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5079509906","display_name":"Cynthia R. C. Osborne","orcid":"https://orcid.org/0000-0001-8040-4985","observed_orcids":["https://orcid.org/0000-0001-8040-4985"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Cynthia R. Osborne","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5010009719","display_name":"Tyler Izatt","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Tyler Izatt","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5071852161","display_name":"Ahmet A. Kurdoglu","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Ahmet Kurdoglu","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5112906139","display_name":"Angela Baker","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Angela Baker","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5074032728","display_name":"Julie M. Koeman","orcid":"https://orcid.org/0000-0002-8888-4191","observed_orcids":["https://orcid.org/0000-0002-8888-4191"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Julie Koeman","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5001633495","display_name":"C\u00e1t\u00e1lin B\u00e1rb\u00e1cioru","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Catalin Barbacioru","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5002211631","display_name":"Onur Sakarya","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Onur Sakarya","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5039524746","display_name":"Francisco M. De La Vega","orcid":"https://orcid.org/0000-0002-9228-2097","observed_orcids":["https://orcid.org/0000-0002-9228-2097"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Francisco M. De La Vega","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5000721597","display_name":"Asim S. Siddiqui","orcid":"https://orcid.org/0000-0002-0359-2334","observed_orcids":["https://orcid.org/0000-0002-0359-2334"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Asim Siddiqui","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5109602575","display_name":"Linh Hoang","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Linh Hoang","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5085613881","display_name":"Paul R. Billings","orcid":"https://orcid.org/0000-0003-1198-0537","observed_orcids":["https://orcid.org/0000-0003-1198-0537"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Paul R. Billings","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5076385474","display_name":"Bodour Salhia","orcid":"https://orcid.org/0000-0003-3843-3621","observed_orcids":["https://orcid.org/0000-0003-3843-3621"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Bodour Salhia","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5060992997","display_name":"Anthony W. Tolcher","orcid":"https://orcid.org/0000-0002-6322-9721","observed_orcids":["https://orcid.org/0000-0002-6322-9721"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Anthony W. Tolcher","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5032713796","display_name":"Jeffrey M. Trent","orcid":"https://orcid.org/0000-0003-0183-4202","observed_orcids":["https://orcid.org/0000-0003-0183-4202"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Jeffrey M. Trent","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5054693021","display_name":"Spyro Mousses","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Spyro Mousses","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5080900202","display_name":"Daniel D. Von Hoff","orcid":"https://orcid.org/0000-0003-4723-7681","observed_orcids":["https://orcid.org/0000-0003-4723-7681"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Daniel Von Hoff","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"last","author":{"id":"https://openalex.org/A5080927178","display_name":"John David Carpten","orcid":"https://orcid.org/0000-0002-6862-2821","observed_orcids":["https://orcid.org/0000-0002-6862-2821"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"John D. Carpten","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]}],"institutions":[],"countries_distinct_count":0,"institutions_distinct_count":0,"corresponding_author_ids":[],"corresponding_institution_ids":[],"apc_list":null,"apc_paid":null,"fwci":null,"has_fulltext":false,"cited_by_count":0,"citation_normalized_percentile":null,"cited_by_percentile_year":null,"biblio":{"volume":null,"issue":null,"first_page":null,"last_page":null},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10183","display_name":"Breast Cancer Treatment Studies","score":0.5317000150680542,"subfield":{"id":"https://openalex.org/subfields/1306","display_name":"Cancer Research"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T10183","display_name":"Breast Cancer Treatment Studies","score":0.5317000150680542,"subfield":{"id":"https://openalex.org/subfields/1306","display_name":"Cancer Research"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T11287","display_name":"Cancer Genomics and Diagnostics","score":0.3230000138282776,"subfield":{"id":"https://openalex.org/subfields/1306","display_name":"Cancer Research"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10769","display_name":"BRCA gene mutations in cancer","score":0.06920000165700912,"subfield":{"id":"https://openalex.org/subfields/1311","display_name":"Genetics"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/metastatic-triple-negative-breast-cancer","display_name":"metastatic triple-negative breast cancer","score":0.9879999756813049},{"id":"https://openalex.org/keywords/rb1","display_name":"RB1","score":0.7739999890327454},{"id":"https://openalex.org/keywords/homozygous-deletion","display_name":"homozygous deletion","score":0.9890000224113464},{"id":"https://openalex.org/keywords/therapeutic-vulnerabilities","display_name":"therapeutic vulnerabilities","score":0.6489999890327454},{"id":"https://openalex.org/keywords/genome-sequencing","display_name":"genome sequencing","score":0.6349999904632568},{"id":"https://openalex.org/keywords/transcriptome-sequencing","display_name":"transcriptome sequencing","score":0.9020000100135803}],"concepts":[{"id":"https://openalex.org/C2780110267","wikidata":"https://www.wikidata.org/wiki/Q7843332","display_name":"Triple-negative breast cancer","level":4,"score":0.8014482259750366},{"id":"https://openalex.org/C530470458","wikidata":"https://www.wikidata.org/wiki/Q128581","display_name":"Breast cancer","level":3,"score":0.6052459478378296},{"id":"https://openalex.org/C162317418","wikidata":"https://www.wikidata.org/wiki/Q252857","display_name":"Transcriptome","level":4,"score":0.554921567440033},{"id":"https://openalex.org/C143998085","wikidata":"https://www.wikidata.org/wiki/Q162555","display_name":"Oncology","level":1,"score":0.4690585136413574},{"id":"https://openalex.org/C141231307","wikidata":"https://www.wikidata.org/wiki/Q7020","display_name":"Genome","level":3,"score":0.456708163022995},{"id":"https://openalex.org/C502942594","wikidata":"https://www.wikidata.org/wiki/Q3421914","display_name":"Cancer research","level":1,"score":0.4244583547115326},{"id":"https://openalex.org/C2775930923","wikidata":"https://www.wikidata.org/wiki/Q12859063","display_name":"Metastatic breast cancer","level":4,"score":0.422667533159256},{"id":"https://openalex.org/C70721500","wikidata":"https://www.wikidata.org/wiki/Q177005","display_name":"Computational biology","level":1,"score":0.3788573741912842},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.36020439863204956},{"id":"https://openalex.org/C121608353","wikidata":"https://www.wikidata.org/wiki/Q12078","display_name":"Cancer","level":2,"score":0.3600393533706665},{"id":"https://openalex.org/C54355233","wikidata":"https://www.wikidata.org/wiki/Q7162","display_name":"Genetics","level":1,"score":0.3564571738243103},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.35242268443107605},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.30990901589393616},{"id":"https://openalex.org/C104317684","wikidata":"https://www.wikidata.org/wiki/Q7187","display_name":"Gene","level":2,"score":0.2992837727069855},{"id":"https://openalex.org/C150194340","wikidata":"https://www.wikidata.org/wiki/Q26972","display_name":"Gene expression","level":3,"score":0.10951671004295349}],"mesh":[],"locations_count":1,"locations":[{"id":"doi:10.1158/1535-7163.22498360","doi":"https://doi.org/10.1158/1535-7163.22498360","is_oa":true,"landing_page_url":"http://dx.doi.org/10.1158/1535-7163.22498360","pdf_url":null,"source":null,"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"acceptedVersion","is_accepted":true,"is_published":false,"raw_source_name":"American Association for Cancer Research","raw_type":"posted-content"}],"best_oa_location":{"id":"doi:10.1158/1535-7163.22498360","doi":"https://doi.org/10.1158/1535-7163.22498360","is_oa":true,"landing_page_url":"http://dx.doi.org/10.1158/1535-7163.22498360","pdf_url":null,"source":null,"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"acceptedVersion","is_accepted":true,"is_published":false,"raw_source_name":"American Association for Cancer Research","raw_type":"posted-content"},"sustainable_development_goals":[{"display_name":"Good health and well-being","score":0.8371999859809875,"id":"https://metadata.un.org/sdg/3"}],"sustainable_development_goals_aurora":[],"study_designs":[],"awards":[],"funders":[],"has_content":{"pdf":false,"grobid_xml":false},"content_urls":null,"referenced_works_count":0,"referenced_works":[],"related_works":["https://openalex.org/W2399513595","https://openalex.org/W3030228103","https://openalex.org/W4388386498","https://openalex.org/W2903919886","https://openalex.org/W2064898491","https://openalex.org/W2028462563","https://openalex.org/W4388541371","https://openalex.org/W2312355201","https://openalex.org/W2942994004","https://openalex.org/W2982720988"],"abstract_inverted_index":{"PDF":[0],"file":[1],"-":[2],"135K,":[3],"Validation":[4],"of":[5],"RB1":[6],"39bp":[7],"homozygous":[8],"deletion":[9],"in":[10],"mTNBC1":[11]},"counts_by_year":[],"updated_date":"2026-10-14T16:39:01.820549","created_date":"2025-10-10T00:00:00"}