{"id":"https://openalex.org/W4362593025","doi":"https://doi.org/10.1158/1538-7445.am2023-6029","title":"Abstract 6029: Multi-omic landscape of squamous cell lung cancer","display_name":"Abstract 6029: Multi-omic landscape of squamous cell lung cancer","publication_year":2023,"publication_date":"2023-04-04","ids":{"openalex":"https://openalex.org/W4362593025","doi":"https://doi.org/10.1158/1538-7445.am2023-6029"},"language":"en","primary_location":{"id":"doi:10.1158/1538-7445.am2023-6029","doi":"https://doi.org/10.1158/1538-7445.am2023-6029","is_oa":false,"landing_page_url":"http://dx.doi.org/10.1158/1538-7445.am2023-6029","pdf_url":null,"source":{"id":"https://openalex.org/S168522863","display_name":"Cancer Research","issn_l":"0008-5472","issn":["0008-5472","1538-7445"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-a","doyens","jufo-3","ki-jl-3","medline","norway-2","poland-200","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320273","host_organization_name":"American Association for Cancer Research","host_organization_lineage":["https://openalex.org/P4310320273"],"host_organization_lineage_names":["American Association for Cancer Research"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Cancer Research","raw_type":"journal-article"},"volume":null,"type":"conference-abstract","indexed_in":["crossref"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5087467089","display_name":"Paul A. Stewart","orcid":"https://orcid.org/0000-0003-0882-308X","observed_orcids":["https://orcid.org/0000-0003-0882-308X"]},"institutions":[{"id":"https://openalex.org/I3019308854","display_name":"Moffitt Cancer Center","ror":"https://ror.org/01xf75524","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I3019308854"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Paul Stewart","raw_affiliation_strings":["1Moffitt Cancer Center, Tampa, FL;"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"1Moffitt Cancer Center, Tampa, FL;","institution_ids":["https://openalex.org/I3019308854"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5010429184","display_name":"Ashley Lui","orcid":"https://orcid.org/0000-0003-4090-4680","observed_orcids":["https://orcid.org/0000-0003-4090-4680"]},"institutions":[{"id":"https://openalex.org/I3019308854","display_name":"Moffitt Cancer Center","ror":"https://ror.org/01xf75524","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I3019308854"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Ashley Lui","raw_affiliation_strings":["1Moffitt Cancer Center, Tampa, FL;"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"1Moffitt Cancer Center, Tampa, FL;","institution_ids":["https://openalex.org/I3019308854"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5003366587","display_name":"Eric A. Welsh","orcid":"https://orcid.org/0000-0002-9302-3855","observed_orcids":["https://orcid.org/0000-0002-9302-3855"]},"institutions":[{"id":"https://openalex.org/I3019308854","display_name":"Moffitt Cancer Center","ror":"https://ror.org/01xf75524","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I3019308854"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Eric Welsh","raw_affiliation_strings":["1Moffitt Cancer Center, Tampa, FL;"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"1Moffitt Cancer Center, Tampa, FL;","institution_ids":["https://openalex.org/I3019308854"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5003183589","display_name":"Dalia Ercan","orcid":"https://orcid.org/0000-0002-2425-0691","observed_orcids":["https://orcid.org/0000-0002-2425-0691"]},"institutions":[{"id":"https://openalex.org/I3019308854","display_name":"Moffitt Cancer Center","ror":"https://ror.org/01xf75524","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I3019308854"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Dalia Ercan","raw_affiliation_strings":["1Moffitt Cancer Center, Tampa, FL;"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"1Moffitt Cancer Center, Tampa, FL;","institution_ids":["https://openalex.org/I3019308854"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5031775788","display_name":"Vanessa Y. Rubio","orcid":"https://orcid.org/0000-0003-1214-4397","observed_orcids":["https://orcid.org/0000-0003-1214-4397"]},"institutions":[{"id":"https://openalex.org/I3019308854","display_name":"Moffitt Cancer Center","ror":"https://ror.org/01xf75524","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I3019308854"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Vanessa Rubio","raw_affiliation_strings":["1Moffitt Cancer Center, Tampa, FL;"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"1Moffitt Cancer Center, Tampa, FL;","institution_ids":["https://openalex.org/I3019308854"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5001890985","display_name":"Hayley D. Ackerman","orcid":"https://orcid.org/0000-0002-1094-7949","observed_orcids":["https://orcid.org/0000-0002-1094-7949"]},"institutions":[{"id":"https://openalex.org/I3019308854","display_name":"Moffitt Cancer Center","ror":"https://ror.org/01xf75524","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I3019308854"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Hayley Ackerman","raw_affiliation_strings":["1Moffitt Cancer Center, Tampa, FL;"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"1Moffitt Cancer Center, Tampa, FL;","institution_ids":["https://openalex.org/I3019308854"]}]},{"author_position":"middle","author":{"id":null,"display_name":"Guohui Li","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I4401726964","display_name":"Zymergen (United States)","ror":"https://ror.org/006c9jk14","country_code":"US","type":"company","lineage":["https://openalex.org/I4401726964"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Guohui Li","raw_affiliation_strings":["2Zymergen, Emeryville, CA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"2Zymergen, Emeryville, CA","institution_ids":["https://openalex.org/I4401726964"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5076672524","display_name":"Bin Fang","orcid":"https://orcid.org/0000-0002-7636-1318","observed_orcids":["https://orcid.org/0000-0002-7636-1318","https://orcid.org/0000-0003-0506-2932"]},"institutions":[{"id":"https://openalex.org/I3019308854","display_name":"Moffitt Cancer Center","ror":"https://ror.org/01xf75524","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I3019308854"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Bin Fang","raw_affiliation_strings":["1Moffitt Cancer Center, Tampa, FL;"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"1Moffitt Cancer Center, Tampa, FL;","institution_ids":["https://openalex.org/I3019308854"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5086603901","display_name":"Steven A. Eschrich","orcid":"https://orcid.org/0000-0002-9833-2788","observed_orcids":["https://orcid.org/0000-0002-9833-2788"]},"institutions":[{"id":"https://openalex.org/I3019308854","display_name":"Moffitt Cancer Center","ror":"https://ror.org/01xf75524","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I3019308854"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Steven Eschrich","raw_affiliation_strings":["1Moffitt Cancer Center, Tampa, FL;"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"1Moffitt Cancer Center, Tampa, FL;","institution_ids":["https://openalex.org/I3019308854"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5002876951","display_name":"John M. Koomen","orcid":"https://orcid.org/0000-0002-3818-1762","observed_orcids":["https://orcid.org/0000-0002-3818-1762"]},"institutions":[{"id":"https://openalex.org/I3019308854","display_name":"Moffitt Cancer Center","ror":"https://ror.org/01xf75524","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I3019308854"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"John Koomen","raw_affiliation_strings":["1Moffitt Cancer Center, Tampa, FL;"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"1Moffitt Cancer Center, Tampa, FL;","institution_ids":["https://openalex.org/I3019308854"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5005857392","display_name":"Elsa Renee Flores","orcid":"https://orcid.org/0000-0002-6173-2403","observed_orcids":["https://orcid.org/0000-0002-6173-2403"]},"institutions":[{"id":"https://openalex.org/I3019308854","display_name":"Moffitt Cancer Center","ror":"https://ror.org/01xf75524","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I3019308854"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Elsa Flores","raw_affiliation_strings":["1Moffitt Cancer Center, Tampa, FL;"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"1Moffitt Cancer Center, Tampa, FL;","institution_ids":["https://openalex.org/I3019308854"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5064494204","display_name":"Eric B. Haura","orcid":"https://orcid.org/0000-0003-3114-1909","observed_orcids":["https://orcid.org/0000-0003-3114-1909"]},"institutions":[{"id":"https://openalex.org/I3019308854","display_name":"Moffitt Cancer Center","ror":"https://ror.org/01xf75524","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I3019308854"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Eric Haura","raw_affiliation_strings":["1Moffitt Cancer Center, Tampa, FL;"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"1Moffitt Cancer Center, Tampa, FL;","institution_ids":["https://openalex.org/I3019308854"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5076253640","display_name":"Gina M. DeNicola","orcid":"https://orcid.org/0000-0001-6611-6696","observed_orcids":["https://orcid.org/0000-0001-6611-6696"]},"institutions":[{"id":"https://openalex.org/I3019308854","display_name":"Moffitt Cancer Center","ror":"https://ror.org/01xf75524","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I3019308854"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Gina DeNicola","raw_affiliation_strings":["1Moffitt Cancer Center, Tampa, FL;"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"1Moffitt Cancer Center, Tampa, FL;","institution_ids":["https://openalex.org/I3019308854"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":2,"corresponding_author_ids":[],"corresponding_institution_ids":[],"apc_list":null,"apc_paid":null,"fwci":null,"has_fulltext":false,"cited_by_count":0,"citation_normalized_percentile":null,"cited_by_percentile_year":null,"biblio":{"volume":"83","issue":"7_Supplement","first_page":"6029","last_page":"6029"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T12334","display_name":"Lung Cancer Research Studies","score":0.365200012922287,"subfield":{"id":"https://openalex.org/subfields/2730","display_name":"Oncology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T12334","display_name":"Lung Cancer Research Studies","score":0.365200012922287,"subfield":{"id":"https://openalex.org/subfields/2730","display_name":"Oncology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10417","display_name":"Lung Cancer Treatments and Mutations","score":0.2013999968767166,"subfield":{"id":"https://openalex.org/subfields/2740","display_name":"Pulmonary and Respiratory Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10836","display_name":"Metabolomics and Mass Spectrometry Studies","score":0.20100000500679016,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/lung-squamous-cell-carcinoma","display_name":"lung squamous cell carcinoma","score":0.996999979019165},{"id":"https://openalex.org/keywords/multi-omics-integration","display_name":"multi-omics integration","score":0.7289999723434448},{"id":"https://openalex.org/keywords/proteomic-subtypes","display_name":"proteomic subtypes","score":0.9739999771118164},{"id":"https://openalex.org/keywords/glutathione","display_name":"glutathione","score":0.7419999837875366},{"id":"https://openalex.org/keywords/tertiary-lymphoid-structures","display_name":"tertiary lymphoid structures","score":0.890999972820282},{"id":"https://openalex.org/keywords/tumor-immune-infiltration","display_name":"tumor immune infiltration","score":0.8600000143051147},{"id":"https://openalex.org/keywords/tumor-metabolism","display_name":"cancer metabolism","score":0.6259999871253967},{"id":"https://openalex.org/keywords/ascorbate-and-aldarate-metabolism","display_name":"ascorbate and aldarate metabolism","score":0.7979999780654907},{"id":"https://openalex.org/keywords/tumor-suppressor-genes","display_name":"tumor suppressor","score":0.35199999809265137},{"id":"https://openalex.org/keywords/tumor-suppressor-loss","display_name":"tumor suppressor loss","score":0.30399999022483826},{"id":"https://openalex.org/keywords/tumor-immune-microenvironment","display_name":"tumor immune microenvironment","score":0.3179999887943268},{"id":"https://openalex.org/keywords/untargeted-metabolomics","display_name":"untargeted metabolomics","score":0.5839999914169312}],"concepts":[{"id":"https://openalex.org/C21565614","wikidata":"https://www.wikidata.org/wiki/Q12149006","display_name":"Metabolomics","level":2,"score":0.7238185405731201},{"id":"https://openalex.org/C46111723","wikidata":"https://www.wikidata.org/wiki/Q471857","display_name":"Proteomics","level":3,"score":0.5979506969451904},{"id":"https://openalex.org/C162317418","wikidata":"https://www.wikidata.org/wiki/Q252857","display_name":"Transcriptome","level":4,"score":0.5727754831314087},{"id":"https://openalex.org/C104397665","wikidata":"https://www.wikidata.org/wiki/Q860947","display_name":"Proteome","level":2,"score":0.49471160769462585},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.48800864815711975},{"id":"https://openalex.org/C121608353","wikidata":"https://www.wikidata.org/wiki/Q12078","display_name":"Cancer","level":2,"score":0.4724828600883484},{"id":"https://openalex.org/C502942594","wikidata":"https://www.wikidata.org/wiki/Q3421914","display_name":"Cancer research","level":1,"score":0.4521234333515167},{"id":"https://openalex.org/C8891405","wikidata":"https://www.wikidata.org/wiki/Q1059","display_name":"Immune system","level":2,"score":0.4160860776901245},{"id":"https://openalex.org/C70721500","wikidata":"https://www.wikidata.org/wiki/Q177005","display_name":"Computational biology","level":1,"score":0.3899405300617218},{"id":"https://openalex.org/C60644358","wikidata":"https://www.wikidata.org/wiki/Q128570","display_name":"Bioinformatics","level":1,"score":0.33632999658584595},{"id":"https://openalex.org/C55493867","wikidata":"https://www.wikidata.org/wiki/Q7094","display_name":"Biochemistry","level":1,"score":0.23816931247711182},{"id":"https://openalex.org/C203014093","wikidata":"https://www.wikidata.org/wiki/Q101929","display_name":"Immunology","level":1,"score":0.23812639713287354},{"id":"https://openalex.org/C104317684","wikidata":"https://www.wikidata.org/wiki/Q7187","display_name":"Gene","level":2,"score":0.22356754541397095},{"id":"https://openalex.org/C54355233","wikidata":"https://www.wikidata.org/wiki/Q7162","display_name":"Genetics","level":1,"score":0.21620476245880127},{"id":"https://openalex.org/C150194340","wikidata":"https://www.wikidata.org/wiki/Q26972","display_name":"Gene expression","level":3,"score":0.14622491598129272}],"mesh":[],"locations_count":1,"locations":[{"id":"doi:10.1158/1538-7445.am2023-6029","doi":"https://doi.org/10.1158/1538-7445.am2023-6029","is_oa":false,"landing_page_url":"http://dx.doi.org/10.1158/1538-7445.am2023-6029","pdf_url":null,"source":{"id":"https://openalex.org/S168522863","display_name":"Cancer Research","issn_l":"0008-5472","issn":["0008-5472","1538-7445"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-a","doyens","jufo-3","ki-jl-3","medline","norway-2","poland-200","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320273","host_organization_name":"American Association for Cancer Research","host_organization_lineage":["https://openalex.org/P4310320273"],"host_organization_lineage_names":["American Association for Cancer Research"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Cancer Research","raw_type":"journal-article"}],"best_oa_location":null,"sustainable_development_goals":[{"score":0.98580002784729,"id":"https://metadata.un.org/sdg/3","display_name":"Good health and well-being"}],"study_designs":[],"awards":[],"funders":[],"has_content":{"pdf":false,"grobid_xml":false},"content_urls":null,"referenced_works_count":0,"referenced_works":[],"related_works":["https://openalex.org/W4393097118","https://openalex.org/W2967730427","https://openalex.org/W4413997912","https://openalex.org/W4388221674","https://openalex.org/W2741652656","https://openalex.org/W3188077199","https://openalex.org/W7222916084","https://openalex.org/W2079067121","https://openalex.org/W4295745244","https://openalex.org/W4200122155"],"abstract_inverted_index":{"Abstract":[0],"Patients":[1],"with":[2,178,192,261],"squamous":[3,374],"cell":[4,298,375],"lung":[5,299,376],"cancer":[6,377],"(SCC)":[7],"have":[8,28],"high":[9],"unmet":[10],"medical":[11],"need.":[12],"Knowledge":[13],"of":[14,22,40,63,72,77,84,221,225,289,373,381],"these":[15,118,316,320,334],"tumors":[16,135],"is":[17,293],"limited,":[18],"and":[19,57,98,107,167,196,263,312,332,394],"a":[20,34,61,144,151,172,286],"lack":[21],"targetable":[23],"genomic":[24,41],"drivers":[25],"means":[26],"patients":[27],"few":[29],"treatment":[30],"options.":[31],"To":[32],"provide":[33],"detailed":[35],"analysis":[36,149,158],"on":[37,133,143,150],"the":[38,81,86,99,137,193,201,226,267,324,382],"influence":[39,315],"alterations":[42,109],"to":[43,124,163,216,233,295,323,337],"proteome-level":[44],"changes":[45],"in":[46,60,200,328,341],"SCC,":[47],"we":[48,129,230],"previously":[49],"integrated":[50],"DNA":[51],"copy":[52],"number,":[53],"somatic":[54],"mutations,":[55],"RNA-sequencing,":[56],"expression":[58],"proteomics":[59],"cohort":[62,139],"108":[64],"SCC":[65,330],"patients.":[66],"A":[67],"major":[68],"finding":[69],"was":[70,89,102,176,198,213],"identification":[71],"three":[73],"proteomic":[74,119,203,234],"subtypes,":[75,318],"two":[76],"which":[78],"made":[79],"up":[80],"majority":[82],"(87%)":[83],"tumors:":[85],"\u201cInflamed\u201d":[87],"subtype":[88,101,204,235,247,278],"enriched":[90,103,269],"for":[91,104,385],"B-cell":[92],"rich":[93],"tertiary":[94],"lymphoid":[95],"structures":[96],"(TLS),":[97],"\u201cRedox\u201d":[100],"redox":[105,174],"pathways":[106],"NFE2L2/KEAP1":[108,237],"but":[110],"had":[111,248,279],"significantly":[112,280],"less":[113],"immune":[114,179,326],"infiltration.":[115],"We":[116],"hypothesized":[117],"subtypes":[120,220,229],"would":[121],"give":[122],"rise":[123],"distinct":[125],"metabolic":[126,339],"signatures.":[127],"Therefore,":[128],"performed":[130],"untargeted":[131],"metabolomics":[132],"87":[134],"from":[136,188],"same":[138],"using":[140],"chromatographic":[141],"separation":[142],"HILIC":[145],"column,":[146],"followed":[147],"by":[148],"Q":[152],"Exactive":[153],"HF":[154],"mass":[155],"spectrometer.":[156],"This":[157],"yielded":[159],"7,344":[160],"features":[161],"corresponding":[162],"7,072":[164],"unannotated":[165],"metabolites":[166,250],"272":[168],"identified":[169,231],"metabolites.":[170],"Glutathione,":[171],"key":[173],"metabolite,":[175],"anticorrelated":[177],"score":[180],"(R":[181],"=":[182,185,209,272,284],"-0.44,":[183],"padj":[184,208,258],"0.004)":[186],"calculated":[187],"our":[189],"transcriptomic":[190],"data":[191],"ESTIMATE":[194],"algorithm,":[195],"glutathione":[197],"elevated":[199],"Redox":[202],"(0.58":[205],"log2":[206],"ratio,":[207],"9.87E-04).":[210],"Consensus":[211],"clustering":[212],"next":[214],"used":[215],"identify":[217],"novel":[218,338],"metabolomic":[219,228,277,317],"SCC.":[222,342],"Surprisingly,":[223],"none":[224],"five":[227],"corresponded":[232],"or":[236],"alteration":[238],"(Fisher\u2019s":[239],"Exact":[240],"test":[241],"p-values":[242],">":[243],"0.05).":[244],"The":[245],"fifth":[246,276],"332":[249],"(26":[251],"identified)":[252],"differentially":[253],"expressed":[254],"(>":[255],"1.5":[256],"fold-change,":[257],"<":[259],"0.05)":[260],"ascorbate":[262],"aldarate":[264],"metabolism":[265],"as":[266],"top":[268],"pathway":[270],"(padj":[271],"3.36E-04).":[273],"Interestingly,":[274],"this":[275],"higher":[281],"DNp63-alpha":[282],"(p":[283],"2.40E-05),":[285],"primary":[287],"transcript":[288],"delta-N":[290],"p63":[291],"that":[292],"known":[294],"promote":[296],"non-small":[297],"cancer.":[300],"Ongoing":[301],"integrative":[302],"analyses":[303],"across":[304],"omic":[305],"types":[306],"will":[307],"determine":[308],"how":[309,319],"p53,":[310],"p63,":[311],"p73":[313],"transcripts":[314,321,335],"relate":[322,336],"poor":[325],"infiltration":[327],"some":[329],"tumors,":[331],"if":[333],"vulnerabilities":[340],"Citation":[343],"Format:":[344],"Paul":[345],"Stewart,":[346],"Ashley":[347],"Lui,":[348],"Eric":[349,367],"Welsh,":[350],"Dalia":[351],"Ercan,":[352],"Vanessa":[353],"Rubio,":[354],"Hayley":[355],"Ackerman,":[356],"Guohui":[357],"Li,":[358],"Bin":[359],"Fang,":[360],"Steven":[361],"Eschrich,":[362],"John":[363],"Koomen,":[364],"Elsa":[365],"Flores,":[366],"Haura,":[368],"Gina":[369],"DeNicola.":[370],"Multi-omic":[371],"landscape":[372],"[abstract].":[378],"In:":[379],"Proceedings":[380],"American":[383],"Association":[384],"Cancer":[386,405],"Research":[387],"Annual":[388],"Meeting":[389],"2023;":[390],"Part":[391],"1":[392],"(Regular":[393],"Invited":[395],"Abstracts);":[396],"2023":[397],"Apr":[398],"14-19;":[399],"Orlando,":[400],"FL.":[401],"Philadelphia":[402],"(PA):":[403],"AACR;":[404],"Res":[406],"2023;83(7_Suppl):Abstract":[407],"nr":[408],"6029.":[409]},"counts_by_year":[],"updated_date":"2026-10-27T15:51:10.671819","created_date":"2023-04-06T00:00:00"}