{"id":"https://openalex.org/W4362559639","doi":"https://doi.org/10.1158/2159-8290.22540474.v1","title":"Supplementary Figures from Macropinocytosis in Cancer-Associated Fibroblasts Is Dependent on CaMKK2/ARHGEF2 Signaling and Functions to Support Tumor and Stromal Cell Fitness","display_name":"Supplementary Figures from Macropinocytosis in Cancer-Associated Fibroblasts Is Dependent on CaMKK2/ARHGEF2 Signaling and Functions to Support Tumor and Stromal Cell Fitness","publication_year":2023,"publication_date":"2023-04-03","ids":{"openalex":"https://openalex.org/W4362559639","doi":"https://doi.org/10.1158/2159-8290.22540474.v1"},"language":"en","primary_location":{"id":"doi:10.1158/2159-8290.22540474.v1","doi":"https://doi.org/10.1158/2159-8290.22540474.v1","is_oa":true,"landing_page_url":"https://doi.org/10.1158/2159-8290.22540474.v1","pdf_url":"https://aacr.figshare.com/ndownloader/files/40003825","source":null,"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"acceptedVersion","is_accepted":true,"is_published":false,"raw_source_name":"American Association for Cancer Research","raw_type":"posted-content"},"volume":null,"type":"supplementary-materials","indexed_in":["crossref"],"open_access":{"is_oa":true,"oa_status":"gold","oa_url":"https://aacr.figshare.com/ndownloader/files/40003825","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5019159624","display_name":"Yijuan Zhang","orcid":"https://orcid.org/0000-0002-1392-1816","observed_orcids":["https://orcid.org/0000-0002-1392-1816"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Yijuan Zhang","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5017746225","display_name":"Maria Victoria Recouvreux","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"M. Victoria Recouvreux","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":null,"display_name":"Michael Jung","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Michael Jung","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5078733977","display_name":"Koen M.O. Galenkamp","orcid":"https://orcid.org/0000-0001-7220-6516","observed_orcids":["https://orcid.org/0000-0001-7220-6516"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Koen M.O. Galenkamp","raw_affiliation_strings":[],"raw_orcid":"https://orcid.org/0000-0001-7220-6516","affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5100755282","display_name":"Yunbo Li","orcid":"https://orcid.org/0000-0003-3222-858X","observed_orcids":["https://orcid.org/0000-0003-3222-858X"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Yunbo Li","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5019530454","display_name":"Olga P. Zagnitko","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Olga Zagnitko","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5008199007","display_name":"David A. Scott","orcid":"https://orcid.org/0000-0002-8668-2449","observed_orcids":["https://orcid.org/0000-0002-8668-2449"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"David A. Scott","raw_affiliation_strings":[],"raw_orcid":"https://orcid.org/0000-0002-8668-2449","affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5089839809","display_name":"Andrew M. Lowy","orcid":"https://orcid.org/0000-0002-7106-0735","observed_orcids":["https://orcid.org/0000-0002-7106-0735"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Andrew M. Lowy","raw_affiliation_strings":[],"raw_orcid":"https://orcid.org/0000-0002-7106-0735","affiliations":[]},{"author_position":"last","author":{"id":"https://openalex.org/A5080326390","display_name":"Cosimo Commisso","orcid":"https://orcid.org/0000-0002-7884-9210","observed_orcids":["https://orcid.org/0000-0002-7884-9210"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Cosimo Commisso","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]}],"institutions":[],"countries_distinct_count":0,"institutions_distinct_count":0,"corresponding_author_ids":[],"corresponding_institution_ids":[],"apc_list":null,"apc_paid":null,"fwci":null,"has_fulltext":true,"cited_by_count":0,"citation_normalized_percentile":null,"cited_by_percentile_year":null,"biblio":{"volume":null,"issue":null,"first_page":null,"last_page":null},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10617","display_name":"Cellular transport and secretion","score":0.2087000012397766,"subfield":{"id":"https://openalex.org/subfields/1307","display_name":"Cell Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T10617","display_name":"Cellular transport and secretion","score":0.2087000012397766,"subfield":{"id":"https://openalex.org/subfields/1307","display_name":"Cell Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10336","display_name":"Cancer Cells and Metastasis","score":0.08749999850988388,"subfield":{"id":"https://openalex.org/subfields/2730","display_name":"Oncology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T11501","display_name":"TGF-\u03b2 signaling in diseases","score":0.06809999793767929,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/macropinocytosis","display_name":"macropinocytosis","score":1.0},{"id":"https://openalex.org/keywords/cancer-associated-fibroblasts","display_name":"cancer-associated fibroblasts","score":1.0},{"id":"https://openalex.org/keywords/camkk2","display_name":"CAMKK2","score":0.9860000014305115},{"id":"https://openalex.org/keywords/arhgef2","display_name":"ARHGEF2","score":0.996999979019165},{"id":"https://openalex.org/keywords/tumor-microenvironment","display_name":"tumor microenvironment","score":0.7879999876022339},{"id":"https://openalex.org/keywords/signaling-pathways","display_name":"signaling pathways","score":0.3330000042915344}],"concepts":[{"id":"https://openalex.org/C16930146","wikidata":"https://www.wikidata.org/wiki/Q4381253","display_name":"Stromal cell","level":2,"score":0.6923729181289673},{"id":"https://openalex.org/C40017333","wikidata":"https://www.wikidata.org/wiki/Q321362","display_name":"Pinocytosis","level":4,"score":0.6509974002838135},{"id":"https://openalex.org/C2909706936","wikidata":"https://www.wikidata.org/wiki/Q42417562","display_name":"Cancer-Associated Fibroblasts","level":4,"score":0.6414850950241089},{"id":"https://openalex.org/C95444343","wikidata":"https://www.wikidata.org/wiki/Q7141","display_name":"Cell biology","level":1,"score":0.5183914303779602},{"id":"https://openalex.org/C502942594","wikidata":"https://www.wikidata.org/wiki/Q3421914","display_name":"Cancer research","level":1,"score":0.5072733759880066},{"id":"https://openalex.org/C1491633281","wikidata":"https://www.wikidata.org/wiki/Q7868","display_name":"Cell","level":2,"score":0.46089404821395874},{"id":"https://openalex.org/C3020616263","wikidata":"https://www.wikidata.org/wiki/Q1216998","display_name":"Tumor cells","level":2,"score":0.4287572503089905},{"id":"https://openalex.org/C185592680","wikidata":"https://www.wikidata.org/wiki/Q2329","display_name":"Chemistry","level":0,"score":0.4049155116081238},{"id":"https://openalex.org/C2776107976","wikidata":"https://www.wikidata.org/wiki/Q1786433","display_name":"Tumor microenvironment","level":3,"score":0.36411863565444946},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.3345023989677429},{"id":"https://openalex.org/C55493867","wikidata":"https://www.wikidata.org/wiki/Q7094","display_name":"Biochemistry","level":1,"score":0.1849040389060974},{"id":"https://openalex.org/C28005876","wikidata":"https://www.wikidata.org/wiki/Q189814","display_name":"Endocytosis","level":3,"score":0.09404340386390686}],"mesh":[],"locations_count":2,"locations":[{"id":"doi:10.1158/2159-8290.22540474.v1","doi":"https://doi.org/10.1158/2159-8290.22540474.v1","is_oa":true,"landing_page_url":"https://doi.org/10.1158/2159-8290.22540474.v1","pdf_url":"https://aacr.figshare.com/ndownloader/files/40003825","source":null,"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"acceptedVersion","is_accepted":true,"is_published":false,"raw_source_name":"American Association for Cancer Research","raw_type":"posted-content"},{"id":"pmh:oai:figshare.com:article/22540474","doi":null,"is_oa":true,"landing_page_url":"https://figshare.com/articles/journal_contribution/Supplementary_Figures_from_Macropinocytosis_in_Cancer-Associated_Fibroblasts_Is_Dependent_on_CaMKK2_ARHGEF2_Signaling_and_Functions_to_Support_Tumor_and_Stromal_Cell_Fitness/22540474","pdf_url":null,"source":{"id":"https://openalex.org/S4377196282","display_name":"Figshare","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I4210132348","host_organization_name":"Figshare (United Kingdom)","host_organization_lineage":["https://openalex.org/I4210132348"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"","raw_type":"Text"}],"best_oa_location":{"id":"doi:10.1158/2159-8290.22540474.v1","doi":"https://doi.org/10.1158/2159-8290.22540474.v1","is_oa":true,"landing_page_url":"https://doi.org/10.1158/2159-8290.22540474.v1","pdf_url":"https://aacr.figshare.com/ndownloader/files/40003825","source":null,"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"acceptedVersion","is_accepted":true,"is_published":false,"raw_source_name":"American Association for Cancer Research","raw_type":"posted-content"},"sustainable_development_goals":[{"score":0.8048999905586243,"id":"https://metadata.un.org/sdg/3","display_name":"Good health and well-being"}],"study_designs":[],"awards":[],"funders":[],"has_content":{"pdf":true,"grobid_xml":true},"content_urls":{"pdf":"https://content.openalex.org/works/W4362559639.pdf","grobid_xml":"https://content.openalex.org/works/W4362559639.grobid-xml"},"referenced_works_count":0,"referenced_works":[],"related_works":["https://openalex.org/W2945772231","https://openalex.org/W7164843627","https://openalex.org/W7095068791"],"abstract_inverted_index":null,"counts_by_year":[],"updated_date":"2026-10-31T12:09:11.096373","created_date":"2023-04-06T00:00:00"}