{"id":"https://openalex.org/W4362529959","doi":"https://doi.org/10.1158/1940-6207.22523179","title":"Perspective on this Article from Cruciferous Vegetable Feeding Alters UGT1A1 Activity: Diet- and Genotype-Dependent Changes in Serum Bilirubin in a Controlled Feeding Trial","display_name":"Perspective on this Article from Cruciferous Vegetable Feeding Alters UGT1A1 Activity: Diet- and Genotype-Dependent Changes in Serum Bilirubin in a Controlled Feeding Trial","publication_year":2023,"publication_date":"2023-04-03","ids":{"openalex":"https://openalex.org/W4362529959","doi":"https://doi.org/10.1158/1940-6207.22523179"},"language":"en","primary_location":{"id":"doi:10.1158/1940-6207.22523179","doi":"https://doi.org/10.1158/1940-6207.22523179","is_oa":true,"landing_page_url":"https://doi.org/10.1158/1940-6207.22523179","pdf_url":null,"source":null,"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"acceptedVersion","is_accepted":true,"is_published":false,"raw_source_name":"American Association for Cancer Research","raw_type":"posted-content"},"volume":null,"type":"other","indexed_in":["crossref"],"open_access":{"is_oa":true,"oa_status":"gold","oa_url":"https://doi.org/10.1158/1940-6207.22523179","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5089050124","display_name":"Sandi L. Navarro","orcid":"https://orcid.org/0000-0002-4260-2486","observed_orcids":["https://orcid.org/0000-0002-4260-2486"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Sandi L. Navarro","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5109349205","display_name":"Sabrina Peterson","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Sabrina Peterson","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5100741518","display_name":"Chu Chen","orcid":"https://orcid.org/0000-0003-2267-8050","observed_orcids":["https://orcid.org/0000-0003-2267-8050","https://orcid.org/0000-0002-8952-573X"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Chu Chen","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5014477842","display_name":"Karen W. Makar","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Karen W. Makar","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5113664322","display_name":"Yvonne Schwarz","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Yvonne Schwarz","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5060789011","display_name":"Irena B. King","orcid":"https://orcid.org/0000-0002-8658-0020","observed_orcids":["https://orcid.org/0000-0002-8658-0020"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Irena B. King","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5059593998","display_name":"Shuying S. Li","orcid":"https://orcid.org/0000-0001-9045-699X","observed_orcids":["https://orcid.org/0000-0001-9045-699X"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Shuying S. Li","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5100412931","display_name":"Lin Li","orcid":"https://orcid.org/0000-0003-1578-9182","observed_orcids":["https://orcid.org/0000-0003-1578-9182"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Lin Li","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5075666233","display_name":"Mark Kestin","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Mark Kestin","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"last","author":{"id":"https://openalex.org/A5019716896","display_name":"Johanna W. Lampe","orcid":"https://orcid.org/0000-0003-2717-3780","observed_orcids":["https://orcid.org/0000-0003-2717-3780"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Johanna W. Lampe","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]}],"institutions":[],"countries_distinct_count":0,"institutions_distinct_count":0,"corresponding_author_ids":[],"corresponding_institution_ids":[],"apc_list":null,"apc_paid":null,"fwci":null,"has_fulltext":false,"cited_by_count":0,"citation_normalized_percentile":null,"cited_by_percentile_year":null,"biblio":{"volume":null,"issue":null,"first_page":null,"last_page":null},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10375","display_name":"Pharmacogenetics and Drug Metabolism","score":0.388700008392334,"subfield":{"id":"https://openalex.org/subfields/3004","display_name":"Pharmacology"},"field":{"id":"https://openalex.org/fields/30","display_name":"Pharmacology, Toxicology and Pharmaceutics"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T10375","display_name":"Pharmacogenetics and Drug Metabolism","score":0.388700008392334,"subfield":{"id":"https://openalex.org/subfields/3004","display_name":"Pharmacology"},"field":{"id":"https://openalex.org/fields/30","display_name":"Pharmacology, Toxicology and Pharmaceutics"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T13984","display_name":"Nutrition, Genetics, and Disease","score":0.3474000096321106,"subfield":{"id":"https://openalex.org/subfields/1311","display_name":"Genetics"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T12068","display_name":"Neonatal Health and Biochemistry","score":0.1695999950170517,"subfield":{"id":"https://openalex.org/subfields/2735","display_name":"Pediatrics, Perinatology and Child Health"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/cruciferous-vegetables","display_name":"cruciferous vegetables","score":0.9950000047683716},{"id":"https://openalex.org/keywords/ugt1a1","display_name":"UGT1A1","score":0.9679999947547913},{"id":"https://openalex.org/keywords/serum-bilirubin","display_name":"serum bilirubin","score":0.8759999871253967},{"id":"https://openalex.org/keywords/bilirubin-conjugation","display_name":"bilirubin conjugation","score":0.7419999837875366},{"id":"https://openalex.org/keywords/genotype-dependent-variation","display_name":"genotype-dependent variation","score":0.6420000195503235}],"concepts":[{"id":"https://openalex.org/C2779487296","wikidata":"https://www.wikidata.org/wiki/Q5189799","display_name":"Cruciferous vegetables","level":3,"score":0.8588579297065735},{"id":"https://openalex.org/C135763542","wikidata":"https://www.wikidata.org/wiki/Q106016","display_name":"Genotype","level":3,"score":0.6351439952850342},{"id":"https://openalex.org/C2777513400","wikidata":"https://www.wikidata.org/wiki/Q104219","display_name":"Bilirubin","level":2,"score":0.5422391295433044},{"id":"https://openalex.org/C12713177","wikidata":"https://www.wikidata.org/wiki/Q1900281","display_name":"Perspective (graphical)","level":2,"score":0.4975264370441437},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.47297728061676025},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.4540948271751404},{"id":"https://openalex.org/C134018914","wikidata":"https://www.wikidata.org/wiki/Q162606","display_name":"Endocrinology","level":1,"score":0.36866939067840576},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.3124714195728302},{"id":"https://openalex.org/C55493867","wikidata":"https://www.wikidata.org/wiki/Q7094","display_name":"Biochemistry","level":1,"score":0.15113422274589539},{"id":"https://openalex.org/C104317684","wikidata":"https://www.wikidata.org/wiki/Q7187","display_name":"Gene","level":2,"score":0.06526696681976318},{"id":"https://openalex.org/C41008148","wikidata":"https://www.wikidata.org/wiki/Q21198","display_name":"Computer science","level":0,"score":0.0},{"id":"https://openalex.org/C121608353","wikidata":"https://www.wikidata.org/wiki/Q12078","display_name":"Cancer","level":2,"score":0.0},{"id":"https://openalex.org/C154945302","wikidata":"https://www.wikidata.org/wiki/Q11660","display_name":"Artificial intelligence","level":1,"score":0.0}],"mesh":[],"locations_count":3,"locations":[{"id":"doi:10.1158/1940-6207.22523179","doi":"https://doi.org/10.1158/1940-6207.22523179","is_oa":true,"landing_page_url":"https://doi.org/10.1158/1940-6207.22523179","pdf_url":null,"source":null,"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"acceptedVersion","is_accepted":true,"is_published":false,"raw_source_name":"American Association for Cancer Research","raw_type":"posted-content"},{"id":"doi:10.1158/1940-6207.22523179.v1","doi":"https://doi.org/10.1158/1940-6207.22523179.v1","is_oa":true,"landing_page_url":"https://doi.org/10.1158/1940-6207.22523179.v1","pdf_url":null,"source":null,"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"acceptedVersion","is_accepted":true,"is_published":false,"raw_source_name":"American Association for Cancer Research","raw_type":"posted-content"},{"id":"pmh:oai:figshare.com:article/22523179","doi":null,"is_oa":true,"landing_page_url":"https://figshare.com/articles/dataset/Perspective_on_this_Article_from_Cruciferous_Vegetable_Feeding_Alters_UGT1A1_Activity_Diet-_and_Genotype-Dependent_Changes_in_Serum_Bilirubin_in_a_Controlled_Feeding_Trial/22523179","pdf_url":null,"source":{"id":"https://openalex.org/S4377196282","display_name":"Figshare","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I4210132348","host_organization_name":"Figshare (United Kingdom)","host_organization_lineage":["https://openalex.org/I4210132348"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"","raw_type":"Dataset"}],"best_oa_location":{"id":"doi:10.1158/1940-6207.22523179","doi":"https://doi.org/10.1158/1940-6207.22523179","is_oa":true,"landing_page_url":"https://doi.org/10.1158/1940-6207.22523179","pdf_url":null,"source":null,"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"acceptedVersion","is_accepted":true,"is_published":false,"raw_source_name":"American Association for Cancer Research","raw_type":"posted-content"},"sustainable_development_goals":[{"id":"https://metadata.un.org/sdg/2","score":0.991100013256073,"display_name":"Zero hunger"}],"study_designs":[],"awards":[],"funders":[],"has_content":{"pdf":false,"grobid_xml":false},"content_urls":null,"referenced_works_count":0,"referenced_works":[],"related_works":["https://openalex.org/W2119080223","https://openalex.org/W4392700759","https://openalex.org/W2115208364","https://openalex.org/W2149776759","https://openalex.org/W2146925755","https://openalex.org/W2579161113","https://openalex.org/W2461330380","https://openalex.org/W3157686223","https://openalex.org/W2093106803","https://openalex.org/W7162558106"],"abstract_inverted_index":{"Perspective":[0],"on":[1],"this":[2],"Article":[3],"from":[4],"Cruciferous":[5],"Vegetable":[6],"Feeding":[7,21],"Alters":[8],"UGT1A1":[9],"Activity:":[10],"Diet-":[11],"and":[12],"Genotype-Dependent":[13],"Changes":[14],"in":[15,18],"Serum":[16],"Bilirubin":[17],"a":[19],"Controlled":[20],"Trial":[22]},"counts_by_year":[],"updated_date":"2026-11-04T10:54:05.112534","created_date":"2023-04-06T00:00:00"}