{"id":"https://openalex.org/W4362525890","doi":"https://doi.org/10.1158/1535-7163.22496727","title":"Supplementary Figure 3 from A Molecular Screening Approach to Identify and Characterize Inhibitors of Glioblastoma Stem Cells","display_name":"Supplementary Figure 3 from A Molecular Screening Approach to Identify and Characterize Inhibitors of Glioblastoma Stem Cells","publication_year":2023,"publication_date":"2023-04-03","ids":{"openalex":"https://openalex.org/W4362525890","doi":"https://doi.org/10.1158/1535-7163.22496727"},"language":"en","primary_location":{"id":"doi:10.1158/1535-7163.22496727","doi":"https://doi.org/10.1158/1535-7163.22496727","is_oa":true,"landing_page_url":"http://dx.doi.org/10.1158/1535-7163.22496727","pdf_url":null,"source":null,"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"acceptedVersion","is_accepted":true,"is_published":false,"raw_source_name":"American Association for Cancer Research","raw_type":"posted-content"},"volume":null,"type":"supplementary-materials","is_traditional":false,"indexed_in":["crossref"],"open_access":{"is_oa":true,"oa_status":"gold","oa_url":"http://dx.doi.org/10.1158/1535-7163.22496727","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5023378099","display_name":"Koppany Visnyei","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Koppany Visnyei","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5110967773","display_name":"Hideyuki Onodera","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Hideyuki Onodera","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5045676945","display_name":"Robert D. Damoiseaux","orcid":"https://orcid.org/0000-0002-7611-7534","observed_orcids":["https://orcid.org/0000-0002-7611-7534"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Robert Damoiseaux","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5041677467","display_name":"Kuniyasu Saigusa","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Kuniyasu Saigusa","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5084034333","display_name":"Syuzanna Petrosyan","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Syuzanna Petrosyan","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5112905627","display_name":"David DE VRIES","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"David De Vries","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5071812459","display_name":"Denise Ferrari","orcid":"https://orcid.org/0000-0001-6473-6293","observed_orcids":["https://orcid.org/0000-0001-6473-6293"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Denise Ferrari","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":null,"display_name":"Jonathan Saxe","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Jonathan Saxe","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5044220421","display_name":"Eduard H. Panosyan","orcid":"https://orcid.org/0000-0003-1701-1251","observed_orcids":["https://orcid.org/0000-0003-1701-1251"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Eduard H. Panosyan","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5048608426","display_name":"Michael D. Masterman-Smith","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Michael Masterman-Smith","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5037036753","display_name":"Jack Mottahedeh","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Jack Mottahedeh","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5056283289","display_name":"Kenneth A. Bradley","orcid":"https://orcid.org/0000-0002-4757-5122","observed_orcids":["https://orcid.org/0000-0002-4757-5122"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Kenneth A. Bradley","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5100757495","display_name":"Jing Huang","orcid":"https://orcid.org/0000-0002-9607-7250","observed_orcids":["https://orcid.org/0000-0002-9607-7250"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Jing Huang","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5037586820","display_name":"Chiara Sabatti","orcid":"https://orcid.org/0000-0001-5829-9058","observed_orcids":["https://orcid.org/0000-0001-5829-9058"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Chiara Sabatti","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5037386621","display_name":"Ichiro Nakano","orcid":"https://orcid.org/0000-0002-0916-3207","observed_orcids":["https://orcid.org/0000-0002-0916-3207"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Ichiro Nakano","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"last","author":{"id":"https://openalex.org/A5062310885","display_name":"Harley I. Kornblum","orcid":"https://orcid.org/0000-0002-3779-4540","observed_orcids":["https://orcid.org/0000-0002-3779-4540"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Harley I. Kornblum","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]}],"institutions":[],"countries_distinct_count":0,"institutions_distinct_count":0,"corresponding_author_ids":[],"corresponding_institution_ids":[],"apc_list":null,"apc_paid":null,"fwci":null,"has_fulltext":false,"cited_by_count":0,"citation_normalized_percentile":null,"cited_by_percentile_year":null,"biblio":{"volume":null,"issue":null,"first_page":null,"last_page":null},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10129","display_name":"Glioma Diagnosis and Treatment","score":0.8862000107765198,"subfield":{"id":"https://openalex.org/subfields/2730","display_name":"Oncology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T10129","display_name":"Glioma Diagnosis and Treatment","score":0.8862000107765198,"subfield":{"id":"https://openalex.org/subfields/2730","display_name":"Oncology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10336","display_name":"Cancer Cells and Metastasis","score":0.07980000227689743,"subfield":{"id":"https://openalex.org/subfields/2730","display_name":"Oncology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10414","display_name":"Cannabis and Cannabinoid Research","score":0.020999999716877937,"subfield":{"id":"https://openalex.org/subfields/2736","display_name":"Pharmacology (medical)"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/glioblastoma-stem-cells","display_name":"glioblastoma stem cells","score":0.9929999709129333},{"id":"https://openalex.org/keywords/nada","display_name":"Nada","score":0.9879999756813049},{"id":"https://openalex.org/keywords/drug-sensitivity","display_name":"drug sensitivity","score":0.6330000162124634},{"id":"https://openalex.org/keywords/molecular-screening","display_name":"molecular screening","score":0.49300000071525574},{"id":"https://openalex.org/keywords/chemotherapeutics","display_name":"chemotherapeutics","score":0.5619999766349792}],"concepts":[{"id":"https://openalex.org/C28328180","wikidata":"https://www.wikidata.org/wiki/Q48196","display_name":"Stem cell","level":2,"score":0.5245047807693481},{"id":"https://openalex.org/C3020081911","wikidata":"https://www.wikidata.org/wiki/Q3918988","display_name":"Serum concentration","level":2,"score":0.471280038356781},{"id":"https://openalex.org/C2776194525","wikidata":"https://www.wikidata.org/wiki/Q282142","display_name":"Glioblastoma","level":2,"score":0.4672265946865082},{"id":"https://openalex.org/C185592680","wikidata":"https://www.wikidata.org/wiki/Q2329","display_name":"Chemistry","level":0,"score":0.4411665201187134},{"id":"https://openalex.org/C153911025","wikidata":"https://www.wikidata.org/wiki/Q7202","display_name":"Molecular biology","level":1,"score":0.41221702098846436},{"id":"https://openalex.org/C81885089","wikidata":"https://www.wikidata.org/wiki/Q189082","display_name":"Cell culture","level":2,"score":0.41120344400405884},{"id":"https://openalex.org/C502942594","wikidata":"https://www.wikidata.org/wiki/Q3421914","display_name":"Cancer research","level":1,"score":0.37045490741729736},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.30793267488479614},{"id":"https://openalex.org/C95444343","wikidata":"https://www.wikidata.org/wiki/Q7141","display_name":"Cell biology","level":1,"score":0.2877146601676941},{"id":"https://openalex.org/C134018914","wikidata":"https://www.wikidata.org/wiki/Q162606","display_name":"Endocrinology","level":1,"score":0.23571071028709412},{"id":"https://openalex.org/C54355233","wikidata":"https://www.wikidata.org/wiki/Q7162","display_name":"Genetics","level":1,"score":0.13579586148262024}],"mesh":[],"locations_count":3,"locations":[{"id":"doi:10.1158/1535-7163.22496727","doi":"https://doi.org/10.1158/1535-7163.22496727","is_oa":true,"landing_page_url":"http://dx.doi.org/10.1158/1535-7163.22496727","pdf_url":null,"source":null,"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"acceptedVersion","is_accepted":true,"is_published":false,"raw_source_name":"American Association for Cancer Research","raw_type":"posted-content"},{"id":"doi:10.1158/1535-7163.22496727.v1","doi":"https://doi.org/10.1158/1535-7163.22496727.v1","is_oa":true,"landing_page_url":"http://dx.doi.org/10.1158/1535-7163.22496727.v1","pdf_url":"https://aacr.figshare.com/articles/journal_contribution/Supplementary_Figure_3_from_A_Molecular_Screening_Approach_to_Identify_and_Characterize_Inhibitors_of_Glioblastoma_Stem_Cells/22496727/1/files/39954753.pdf","source":null,"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"acceptedVersion","is_accepted":true,"is_published":false,"raw_source_name":"American Association for Cancer Research","raw_type":"posted-content"},{"id":"pmh:oai:figshare.com:article/22496727","doi":null,"is_oa":true,"landing_page_url":"https://figshare.com/articles/journal_contribution/Supplementary_Figure_3_from_A_Molecular_Screening_Approach_to_Identify_and_Characterize_Inhibitors_of_Glioblastoma_Stem_Cells/22496727","pdf_url":null,"source":{"id":"https://openalex.org/S4377196282","display_name":"Figshare","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I4210132348","host_organization_name":"Figshare (United Kingdom)","host_organization_lineage":["https://openalex.org/I4210132348"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"","raw_type":"Text"}],"best_oa_location":{"id":"doi:10.1158/1535-7163.22496727","doi":"https://doi.org/10.1158/1535-7163.22496727","is_oa":true,"landing_page_url":"http://dx.doi.org/10.1158/1535-7163.22496727","pdf_url":null,"source":null,"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"acceptedVersion","is_accepted":true,"is_published":false,"raw_source_name":"American Association for Cancer Research","raw_type":"posted-content"},"sustainable_development_goals":[{"id":"https://metadata.un.org/sdg/3","score":0.8371999859809875,"display_name":"Good health and well-being"}],"study_designs":[],"awards":[],"funders":[],"has_content":{"grobid_xml":true,"pdf":true},"content_urls":{"pdf":"https://content.openalex.org/works/W4362525890.pdf","grobid_xml":"https://content.openalex.org/works/W4362525890.grobid-xml"},"referenced_works_count":0,"referenced_works":[],"related_works":["https://openalex.org/W7100709277","https://openalex.org/W4392687497","https://openalex.org/W2165921443","https://openalex.org/W2588842086","https://openalex.org/W4394817188","https://openalex.org/W2792537129","https://openalex.org/W4416140905","https://openalex.org/W2955426696","https://openalex.org/W2051239671","https://openalex.org/W4246922026"],"abstract_inverted_index":{"PDF":[0],"File":[1],"-":[2,4],"(55K)":[3],"Sensitivity":[5],"of":[6,18,41,68],"GBM":[7],"cells":[8,23,31,73,107,115,125,134],"to":[9,34,49,64],"OLDA,":[10],"PALDA":[11],"and":[12,43,76],"NADA":[13],"changes":[14],"as":[15],"a":[16,59,94],"function":[17],"time,":[19],"for":[20,38,47,140],"which":[21],"the":[22,65,144],"were":[24,32,44,135],"cultured":[25,136],"in":[26,55,70,111,117,121,127,137],"GSC":[27,35,80],"-enriching":[28,36],"media":[29,37,57,89,139],"GBM107":[30],"exposed":[33],"increasing":[39],"amounts":[40],"time":[42,84],"then":[45],"screened":[46,116,126],"sensitivity":[48],"dopaminergic":[50],"cannabinoid":[51],"compounds.":[52],"While":[53],"screening":[54],"serum-containing":[56],"requires":[58],"higher":[60],"compound":[61],"concentration":[62],"due":[63],"protective":[66],"effect":[67],"serum":[69,113,118,123,132],"general,":[71],"serum-derived":[72],"become":[74],"more":[75,77],"sensitive":[78],"towards":[79],"-specific":[81],"compounds":[82],"over":[83],"after":[85],"transfer":[86],"into":[87],"sphere":[88,128,138],"(A,":[90],"B,":[91],"C).":[92],"Such":[93],"difference":[95],"is":[96],"not":[97],"present":[98],"using":[99],"non-GSC":[100],"selective":[101],"chemotherapeutics":[102],"(D)":[103],"or":[104],"non-GBM":[105],"control":[106],"(E,":[108],"F).":[109],"('ser":[110],"ser':":[112],"derived":[114,124,133],"media;":[119,129],"'ser":[120],"sph':":[122,131],"'1d":[130],"one":[141],"day":[142],"before":[143],"screen,":[145],"etc.)":[146]},"counts_by_year":[],"updated_date":"2026-11-04T10:54:05.112534","created_date":"2023-04-06T00:00:00"}