{"id":"https://openalex.org/W4362525808","doi":"https://doi.org/10.1158/1535-7163.22497769","title":"Supplementary Figure 1 from A Human Single-Domain Antibody Elicits Potent Antitumor Activity by Targeting an Epitope in Mesothelin Close to the Cancer Cell Surface","display_name":"Supplementary Figure 1 from A Human Single-Domain Antibody Elicits Potent Antitumor Activity by Targeting an Epitope in Mesothelin Close to the Cancer Cell Surface","publication_year":2023,"publication_date":"2023-04-03","ids":{"openalex":"https://openalex.org/W4362525808","doi":"https://doi.org/10.1158/1535-7163.22497769"},"language":"en","primary_location":{"id":"doi:10.1158/1535-7163.22497769","doi":"https://doi.org/10.1158/1535-7163.22497769","is_oa":true,"landing_page_url":"http://dx.doi.org/10.1158/1535-7163.22497769","pdf_url":null,"source":null,"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"acceptedVersion","is_accepted":true,"is_published":false,"raw_source_name":"American Association for Cancer Research","raw_type":"posted-content"},"volume":null,"type":"supplementary-materials","indexed_in":["crossref"],"open_access":{"is_oa":true,"oa_status":"gold","oa_url":"http://dx.doi.org/10.1158/1535-7163.22497769","any_repository_has_fulltext":null},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5078028224","display_name":"Zhewei Tang","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Zhewei Tang","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5031701013","display_name":"Mingqian Feng","orcid":"https://orcid.org/0000-0002-0654-8224","observed_orcids":["https://orcid.org/0000-0002-0654-8224"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Mingqian Feng","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":null,"display_name":"Wei Gao","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Wei Gao","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5043923536","display_name":"Yen Phung","orcid":"https://orcid.org/0000-0002-9094-742X","observed_orcids":["https://orcid.org/0000-0002-9094-742X"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Yen Phung","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5067025401","display_name":"Weizao Chen","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Weizao Chen","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5079271824","display_name":"Amit Chaudhary","orcid":"https://orcid.org/0000-0002-3079-7239","observed_orcids":["https://orcid.org/0000-0002-3079-7239"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Amit Chaudhary","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5055104705","display_name":"Brad St. Croix","orcid":"https://orcid.org/0000-0002-6246-0374","observed_orcids":["https://orcid.org/0000-0002-6246-0374"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Brad St. Croix","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5108478362","display_name":"Min Qian","orcid":"https://orcid.org/0009-0007-5660-964X","observed_orcids":["https://orcid.org/0009-0007-5660-964X"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Min Qian","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5089862290","display_name":"Dimiter Stanchev Dimitrov","orcid":"https://orcid.org/0000-0002-2258-1024","observed_orcids":["https://orcid.org/0000-0002-2258-1024"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Dimiter S. Dimitrov","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"last","author":{"id":"https://openalex.org/A5036066519","display_name":"Mitchell Ho","orcid":"https://orcid.org/0000-0002-9152-5405","observed_orcids":["https://orcid.org/0000-0002-9152-5405"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Mitchell Ho","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]}],"institutions":[],"countries_distinct_count":0,"institutions_distinct_count":0,"corresponding_author_ids":[],"corresponding_institution_ids":[],"apc_list":null,"apc_paid":null,"fwci":null,"has_fulltext":false,"cited_by_count":0,"citation_normalized_percentile":null,"cited_by_percentile_year":null,"biblio":{"volume":null,"issue":null,"first_page":null,"last_page":null},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T12477","display_name":"Toxin Mechanisms and Immunotoxins","score":0.7192000150680542,"subfield":{"id":"https://openalex.org/subfields/2403","display_name":"Immunology"},"field":{"id":"https://openalex.org/fields/24","display_name":"Immunology and Microbiology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T12477","display_name":"Toxin Mechanisms and Immunotoxins","score":0.7192000150680542,"subfield":{"id":"https://openalex.org/subfields/2403","display_name":"Immunology"},"field":{"id":"https://openalex.org/fields/24","display_name":"Immunology and Microbiology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T11016","display_name":"Monoclonal and Polyclonal Antibodies Research","score":0.2687999904155731,"subfield":{"id":"https://openalex.org/subfields/2741","display_name":"Radiology, Nuclear Medicine and Imaging"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10580","display_name":"Immunotherapy and Immune Responses","score":0.004600000102072954,"subfield":{"id":"https://openalex.org/subfields/2403","display_name":"Immunology"},"field":{"id":"https://openalex.org/fields/24","display_name":"Immunology and Microbiology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/nanobodies","display_name":"nanobodies","score":0.9010000228881836},{"id":"https://openalex.org/keywords/mesothelin","display_name":"mesothelin","score":0.9039999842643738},{"id":"https://openalex.org/keywords/recombinant-immunotoxin","display_name":"recombinant immunotoxin","score":0.8899999856948853},{"id":"https://openalex.org/keywords/sd1","display_name":"SD1","score":0.7250000238418579},{"id":"https://openalex.org/keywords/anticancer-activity","display_name":"anticancer activity","score":0.8539999723434448},{"id":"https://openalex.org/keywords/antibody-engineering","display_name":"antibody engineering","score":0.40299999713897705}],"concepts":[{"id":"https://openalex.org/C115085202","wikidata":"https://www.wikidata.org/wiki/Q425665","display_name":"Immunotoxin","level":4,"score":0.8812354803085327},{"id":"https://openalex.org/C2777045440","wikidata":"https://www.wikidata.org/wiki/Q14914057","display_name":"Mesothelin","level":3,"score":0.852196455001831},{"id":"https://openalex.org/C195616568","wikidata":"https://www.wikidata.org/wiki/Q128711","display_name":"Epitope","level":3,"score":0.723316490650177},{"id":"https://openalex.org/C40767141","wikidata":"https://www.wikidata.org/wiki/Q285697","display_name":"Recombinant DNA","level":3,"score":0.706855058670044},{"id":"https://openalex.org/C502942594","wikidata":"https://www.wikidata.org/wiki/Q3421914","display_name":"Cancer research","level":1,"score":0.520271360874176},{"id":"https://openalex.org/C159654299","wikidata":"https://www.wikidata.org/wiki/Q79460","display_name":"Antibody","level":2,"score":0.4939442276954651},{"id":"https://openalex.org/C153911025","wikidata":"https://www.wikidata.org/wiki/Q7202","display_name":"Molecular biology","level":1,"score":0.4818245470523834},{"id":"https://openalex.org/C2781241564","wikidata":"https://www.wikidata.org/wiki/Q1347450","display_name":"Epitope mapping","level":4,"score":0.44981980323791504},{"id":"https://openalex.org/C185592680","wikidata":"https://www.wikidata.org/wiki/Q2329","display_name":"Chemistry","level":0,"score":0.43395617604255676},{"id":"https://openalex.org/C542903549","wikidata":"https://www.wikidata.org/wiki/Q422248","display_name":"Monoclonal antibody","level":3,"score":0.35463452339172363},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.2973071336746216},{"id":"https://openalex.org/C104317684","wikidata":"https://www.wikidata.org/wiki/Q7187","display_name":"Gene","level":2,"score":0.24221017956733704},{"id":"https://openalex.org/C203014093","wikidata":"https://www.wikidata.org/wiki/Q101929","display_name":"Immunology","level":1,"score":0.14091962575912476},{"id":"https://openalex.org/C55493867","wikidata":"https://www.wikidata.org/wiki/Q7094","display_name":"Biochemistry","level":1,"score":0.10984310507774353}],"mesh":[],"locations_count":1,"locations":[{"id":"doi:10.1158/1535-7163.22497769","doi":"https://doi.org/10.1158/1535-7163.22497769","is_oa":true,"landing_page_url":"http://dx.doi.org/10.1158/1535-7163.22497769","pdf_url":null,"source":null,"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"acceptedVersion","is_accepted":true,"is_published":false,"raw_source_name":"American Association for Cancer Research","raw_type":"posted-content"}],"best_oa_location":{"id":"doi:10.1158/1535-7163.22497769","doi":"https://doi.org/10.1158/1535-7163.22497769","is_oa":true,"landing_page_url":"http://dx.doi.org/10.1158/1535-7163.22497769","pdf_url":null,"source":null,"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"acceptedVersion","is_accepted":true,"is_published":false,"raw_source_name":"American Association for Cancer Research","raw_type":"posted-content"},"sustainable_development_goals":[{"score":0.8048999905586243,"id":"https://metadata.un.org/sdg/3","display_name":"Good health and well-being"}],"sustainable_development_goals_aurora":[{"score":0.49000000953674316,"id":"https://metadata.un.org/sdg/3","display_name":"Good health and well-being"}],"study_designs":[],"awards":[],"funders":[],"has_content":{"grobid_xml":false,"pdf":false},"content_urls":null,"referenced_works_count":0,"referenced_works":[],"related_works":["https://openalex.org/W4392687400","https://openalex.org/W2140199061","https://openalex.org/W4362492615","https://openalex.org/W2132214488","https://openalex.org/W1977122810","https://openalex.org/W4392681772","https://openalex.org/W1969194497","https://openalex.org/W2257197146","https://openalex.org/W4362638121","https://openalex.org/W3037889758"],"abstract_inverted_index":{"PDF":[0],"file":[1],"-":[2],"1308K,":[3],"Production":[4],"and":[5],"analysis":[6],"of":[7],"the":[8],"SD1-based":[9],"recombinant":[10],"immunotoxin.":[11]},"counts_by_year":[],"updated_date":"2026-09-27T08:07:27.782135","created_date":"2023-04-06T00:00:00"}