{"id":"https://openalex.org/W4362494737","doi":"https://doi.org/10.1158/1535-7163.22504146","title":"Figure S5 from Nanoconjugation of PSMA-Targeting Ligands Enhances Perinuclear Localization and Improves Efficacy of Delivered Alpha-Particle Emitters against Tumor Endothelial Analogues","display_name":"Figure S5 from Nanoconjugation of PSMA-Targeting Ligands Enhances Perinuclear Localization and Improves Efficacy of Delivered Alpha-Particle Emitters against Tumor Endothelial Analogues","publication_year":2023,"publication_date":"2023-04-03","ids":{"openalex":"https://openalex.org/W4362494737","doi":"https://doi.org/10.1158/1535-7163.22504146"},"language":"en","primary_location":{"id":"doi:10.1158/1535-7163.22504146","doi":"https://doi.org/10.1158/1535-7163.22504146","is_oa":true,"landing_page_url":"https://doi.org/10.1158/1535-7163.22504146","pdf_url":null,"source":null,"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"acceptedVersion","is_accepted":true,"is_published":false,"raw_source_name":"American Association for Cancer Research","raw_type":"posted-content"},"volume":null,"type":"other","indexed_in":["crossref"],"open_access":{"is_oa":true,"oa_status":"gold","oa_url":"https://doi.org/10.1158/1535-7163.22504146","any_repository_has_fulltext":null},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5020232649","display_name":"Charles Zhu","orcid":"https://orcid.org/0000-0003-1431-1806","observed_orcids":["https://orcid.org/0000-0003-1431-1806"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Charles Zhu","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5025541334","display_name":"Amey Bandekar","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Amey Bandekar","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5049694284","display_name":"Michelle Sempkowski","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Michelle Sempkowski","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5029810995","display_name":"Sangeeta Ray Banerjee","orcid":"https://orcid.org/0000-0003-3785-7385","observed_orcids":["https://orcid.org/0000-0003-3785-7385"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Sangeeta Ray Banerjee","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5049568817","display_name":"Martin G. Pomper","orcid":"https://orcid.org/0000-0001-6753-3010","observed_orcids":["https://orcid.org/0000-0001-6753-3010"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Martin G. Pomper","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5050744570","display_name":"Frank Bruchertseifer","orcid":"https://orcid.org/0000-0003-2125-4483","observed_orcids":["https://orcid.org/0000-0003-2125-4483"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Frank Bruchertseifer","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":null,"display_name":"Alfred Morgenstern","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Alfred Morgenstern","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"last","author":{"id":"https://openalex.org/A5000419225","display_name":"Stavroula Sofou","orcid":"https://orcid.org/0000-0003-1735-326X","observed_orcids":["https://orcid.org/0000-0003-1735-326X"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Stavroula Sofou","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]}],"institutions":[],"countries_distinct_count":0,"institutions_distinct_count":0,"corresponding_author_ids":[],"corresponding_institution_ids":[],"apc_list":null,"apc_paid":null,"fwci":null,"has_fulltext":false,"cited_by_count":0,"citation_normalized_percentile":null,"cited_by_percentile_year":null,"biblio":{"volume":null,"issue":null,"first_page":null,"last_page":null},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T11395","display_name":"Radiopharmaceutical Chemistry and Applications","score":0.9984999895095825,"subfield":{"id":"https://openalex.org/subfields/2741","display_name":"Radiology, Nuclear Medicine and Imaging"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T11395","display_name":"Radiopharmaceutical Chemistry and Applications","score":0.9984999895095825,"subfield":{"id":"https://openalex.org/subfields/2741","display_name":"Radiology, Nuclear Medicine and Imaging"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10063","display_name":"Nanoparticle-Based Drug Delivery","score":0.00039999998989515007,"subfield":{"id":"https://openalex.org/subfields/2502","display_name":"Biomaterials"},"field":{"id":"https://openalex.org/fields/25","display_name":"Materials Science"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},{"id":"https://openalex.org/T10725","display_name":"RNA Interference and Gene Delivery","score":9.999999747378752e-05,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/prostate-specific-membrane-antigen","display_name":"prostate-specific membrane antigen","score":0.777999997138977},{"id":"https://openalex.org/keywords/alpha-emitters","display_name":"alpha-emitting radionuclides","score":0.8529999852180481},{"id":"https://openalex.org/keywords/targeted-radionuclide-therapy","display_name":"targeted radionuclide therapy","score":0.8059999942779541},{"id":"https://openalex.org/keywords/human-umbilical-vein-endothelial-cells","display_name":"human umbilical vein endothelial cells","score":0.6819999814033508},{"id":"https://openalex.org/keywords/cell-viability","display_name":"cell viability","score":0.7269999980926514},{"id":"https://openalex.org/keywords/perinuclear-localization","display_name":"perinuclear localization","score":0.8759999871253967},{"id":"https://openalex.org/keywords/radiolabeled-ligands","display_name":"radiolabeled ligands","score":0.6620000004768372}],"concepts":[{"id":"https://openalex.org/C48900799","wikidata":"https://www.wikidata.org/wiki/Q1424376","display_name":"Doubling time","level":3,"score":0.5640140771865845},{"id":"https://openalex.org/C502942594","wikidata":"https://www.wikidata.org/wiki/Q3421914","display_name":"Cancer research","level":1,"score":0.5335695147514343},{"id":"https://openalex.org/C64943373","wikidata":"https://www.wikidata.org/wiki/Q2651003","display_name":"Alpha (finance)","level":4,"score":0.4786442518234253},{"id":"https://openalex.org/C185592680","wikidata":"https://www.wikidata.org/wiki/Q2329","display_name":"Chemistry","level":0,"score":0.46298423409461975},{"id":"https://openalex.org/C7070889","wikidata":"https://www.wikidata.org/wiki/Q902488","display_name":"Monolayer","level":2,"score":0.41637617349624634},{"id":"https://openalex.org/C12554922","wikidata":"https://www.wikidata.org/wiki/Q7100","display_name":"Biophysics","level":1,"score":0.33442237973213196},{"id":"https://openalex.org/C153911025","wikidata":"https://www.wikidata.org/wiki/Q7202","display_name":"Molecular biology","level":1,"score":0.3308866024017334},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.28351014852523804},{"id":"https://openalex.org/C55493867","wikidata":"https://www.wikidata.org/wiki/Q7094","display_name":"Biochemistry","level":1,"score":0.2243218719959259},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.21104565262794495},{"id":"https://openalex.org/C1491633281","wikidata":"https://www.wikidata.org/wiki/Q7868","display_name":"Cell","level":2,"score":0.14983144402503967},{"id":"https://openalex.org/C141071460","wikidata":"https://www.wikidata.org/wiki/Q40821","display_name":"Surgery","level":1,"score":0.061245083808898926},{"id":"https://openalex.org/C49453240","wikidata":"https://www.wikidata.org/wiki/Q1592163","display_name":"Construct validity","level":3,"score":0.0},{"id":"https://openalex.org/C2775944032","wikidata":"https://www.wikidata.org/wiki/Q22907659","display_name":"Patient satisfaction","level":2,"score":0.0}],"mesh":[],"locations_count":1,"locations":[{"id":"doi:10.1158/1535-7163.22504146","doi":"https://doi.org/10.1158/1535-7163.22504146","is_oa":true,"landing_page_url":"https://doi.org/10.1158/1535-7163.22504146","pdf_url":null,"source":null,"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"acceptedVersion","is_accepted":true,"is_published":false,"raw_source_name":"American Association for Cancer Research","raw_type":"posted-content"}],"best_oa_location":{"id":"doi:10.1158/1535-7163.22504146","doi":"https://doi.org/10.1158/1535-7163.22504146","is_oa":true,"landing_page_url":"https://doi.org/10.1158/1535-7163.22504146","pdf_url":null,"source":null,"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"acceptedVersion","is_accepted":true,"is_published":false,"raw_source_name":"American Association for Cancer Research","raw_type":"posted-content"},"sustainable_development_goals":[{"score":0.9391000270843506,"id":"https://metadata.un.org/sdg/3","display_name":"Good health and well-being"}],"study_designs":[],"awards":[],"funders":[],"has_content":{"pdf":false,"grobid_xml":false},"content_urls":null,"referenced_works_count":0,"referenced_works":[],"related_works":["https://openalex.org/W4362494703","https://openalex.org/W4362494552","https://openalex.org/W4362495149","https://openalex.org/W4362495020","https://openalex.org/W4362495033","https://openalex.org/W4362495023","https://openalex.org/W4362494953","https://openalex.org/W2202000729","https://openalex.org/W4281254259","https://openalex.org/W4389380524"],"abstract_inverted_index":{"Viability":[0],"(evaluated":[1],"after":[2,11],"one":[3],"doubling":[4],"time)":[5],"of":[6],"PSMA-positive":[7],"HUVEC":[8],"in":[9],"monolayers":[10],"treatment":[12],"by":[13],"targeted":[14],"radiolabeled":[15],"constructs.":[16]},"counts_by_year":[],"updated_date":"2026-10-11T09:32:39.932853","created_date":"2023-04-05T00:00:00"}