{"id":"https://openalex.org/W4362494697","doi":"https://doi.org/10.1158/1535-7163.22504107","title":"Supplemental Figure 1 from Preclinical Mammalian Safety Studies of EPHARNA (DOPC Nanoliposomal EphA2-Targeted siRNA)","display_name":"Supplemental Figure 1 from Preclinical Mammalian Safety Studies of EPHARNA (DOPC Nanoliposomal EphA2-Targeted siRNA)","publication_year":2023,"publication_date":"2023-04-03","ids":{"openalex":"https://openalex.org/W4362494697","doi":"https://doi.org/10.1158/1535-7163.22504107"},"language":"en","primary_location":{"id":"doi:10.1158/1535-7163.22504107","doi":"https://doi.org/10.1158/1535-7163.22504107","is_oa":true,"landing_page_url":"https://doi.org/10.1158/1535-7163.22504107","pdf_url":null,"source":null,"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"acceptedVersion","is_accepted":true,"is_published":false,"raw_source_name":"American Association for Cancer Research","raw_type":"posted-content"},"volume":null,"type":"supplementary-materials","indexed_in":["crossref"],"open_access":{"is_oa":true,"oa_status":"gold","oa_url":"https://doi.org/10.1158/1535-7163.22504107","any_repository_has_fulltext":null},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5015483526","display_name":"Michael J. Wagner","orcid":"https://orcid.org/0000-0002-0753-9282","observed_orcids":["https://orcid.org/0000-0002-0753-9282"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Michael J. Wagner","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":null,"display_name":"Rahul Mitra","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Rahul Mitra","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5108666496","display_name":"Mark J. McArthur","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Mark J. McArthur","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5109842994","display_name":"Wallace B. Baze","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Wallace Baze","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5112905356","display_name":"Kirstin F. Barnhart","orcid":"https://orcid.org/0009-0009-6762-7282","observed_orcids":["https://orcid.org/0009-0009-6762-7282"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Kirstin Barnhart","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5027588399","display_name":"Sherry Y. Wu","orcid":"https://orcid.org/0000-0002-6051-4252","observed_orcids":["https://orcid.org/0000-0002-6051-4252"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Sherry Y. Wu","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5010129570","display_name":"Cristian Rodriguez\u2010Aguayo","orcid":"https://orcid.org/0000-0002-7880-7723","observed_orcids":["https://orcid.org/0000-0002-7880-7723"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Cristian Rodriguez-Aguayo","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5072661022","display_name":"Xinna Zhang","orcid":"https://orcid.org/0000-0003-4118-2245","observed_orcids":["https://orcid.org/0000-0003-4118-2245"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Xinna Zhang","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5009234043","display_name":"Robert Louis Coleman","orcid":"https://orcid.org/0000-0001-9343-8754","observed_orcids":["https://orcid.org/0000-0001-9343-8754"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Robert L. Coleman","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5023542865","display_name":"Gabriel Lopez\u2010Berestein","orcid":"https://orcid.org/0000-0002-0366-0720","observed_orcids":["https://orcid.org/0000-0002-0366-0720"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Gabriel Lopez-Berestein","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"last","author":{"id":"https://openalex.org/A5100640276","display_name":"Anil K. Sood","orcid":"https://orcid.org/0000-0002-5415-9901","observed_orcids":["https://orcid.org/0000-0002-5415-9901"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Anil K. Sood","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]}],"institutions":[],"countries_distinct_count":0,"institutions_distinct_count":0,"corresponding_author_ids":[],"corresponding_institution_ids":[],"apc_list":null,"apc_paid":null,"fwci":null,"has_fulltext":false,"cited_by_count":0,"citation_normalized_percentile":null,"cited_by_percentile_year":null,"biblio":{"volume":null,"issue":null,"first_page":null,"last_page":null},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10725","display_name":"RNA Interference and Gene Delivery","score":0.9932000041007996,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T10725","display_name":"RNA Interference and Gene Delivery","score":0.9932000041007996,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T14072","display_name":"Immunotoxicology and immune responses","score":0.002199999988079071,"subfield":{"id":"https://openalex.org/subfields/2403","display_name":"Immunology"},"field":{"id":"https://openalex.org/fields/24","display_name":"Immunology and Microbiology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10063","display_name":"Nanoparticle-Based Drug Delivery","score":0.0017000000225380063,"subfield":{"id":"https://openalex.org/subfields/2502","display_name":"Biomaterials"},"field":{"id":"https://openalex.org/fields/25","display_name":"Materials Science"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/ephrin-a2","display_name":"ephrin-A2","score":0.5849999785423279},{"id":"https://openalex.org/keywords/sirna","display_name":"siRNA","score":0.8370000123977661},{"id":"https://openalex.org/keywords/nanoliposomes","display_name":"nanoliposomes","score":0.8769999742507935},{"id":"https://openalex.org/keywords/dopc","display_name":"DOPC","score":0.7229999899864197},{"id":"https://openalex.org/keywords/sirna-delivery","display_name":"siRNA delivery","score":0.4950000047683716},{"id":"https://openalex.org/keywords/preclinical-safety-evaluation","display_name":"preclinical safety","score":0.7429999709129333}],"concepts":[{"id":"https://openalex.org/C150582083","wikidata":"https://www.wikidata.org/wiki/Q18250395","display_name":"EPH receptor A2","level":4,"score":0.8236029148101807},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.48237958550453186},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.2538774609565735},{"id":"https://openalex.org/C170493617","wikidata":"https://www.wikidata.org/wiki/Q208467","display_name":"Receptor","level":2,"score":0.10276332497596741},{"id":"https://openalex.org/C101544691","wikidata":"https://www.wikidata.org/wiki/Q420511","display_name":"Receptor tyrosine kinase","level":3,"score":0.0}],"mesh":[],"locations_count":2,"locations":[{"id":"doi:10.1158/1535-7163.22504107","doi":"https://doi.org/10.1158/1535-7163.22504107","is_oa":true,"landing_page_url":"https://doi.org/10.1158/1535-7163.22504107","pdf_url":null,"source":null,"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"acceptedVersion","is_accepted":true,"is_published":false,"raw_source_name":"American Association for Cancer Research","raw_type":"posted-content"},{"id":"doi:10.1158/1535-7163.22504107.v1","doi":"https://doi.org/10.1158/1535-7163.22504107.v1","is_oa":true,"landing_page_url":"https://doi.org/10.1158/1535-7163.22504107.v1","pdf_url":null,"source":null,"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"acceptedVersion","is_accepted":true,"is_published":false,"raw_source_name":"American Association for Cancer Research","raw_type":"posted-content"}],"best_oa_location":{"id":"doi:10.1158/1535-7163.22504107","doi":"https://doi.org/10.1158/1535-7163.22504107","is_oa":true,"landing_page_url":"https://doi.org/10.1158/1535-7163.22504107","pdf_url":null,"source":null,"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"acceptedVersion","is_accepted":true,"is_published":false,"raw_source_name":"American Association for Cancer Research","raw_type":"posted-content"},"sustainable_development_goals":[{"id":"https://metadata.un.org/sdg/3","score":0.98580002784729,"display_name":"Good health and well-being"}],"study_designs":[],"awards":[],"funders":[],"has_content":{"pdf":false,"grobid_xml":false},"content_urls":null,"referenced_works_count":0,"referenced_works":[],"related_works":["https://openalex.org/W4362494975","https://openalex.org/W2591778805","https://openalex.org/W2500551752","https://openalex.org/W4256169941","https://openalex.org/W4213134573","https://openalex.org/W1567965511","https://openalex.org/W6991057783","https://openalex.org/W4239121927","https://openalex.org/W2140093304","https://openalex.org/W2292478863"],"abstract_inverted_index":{"Primate":[0],"Hematology":[1]},"counts_by_year":[],"updated_date":"2026-11-04T10:54:05.112534","created_date":"2023-04-05T00:00:00"}