{"id":"https://openalex.org/W4362494491","doi":"https://doi.org/10.1158/1535-7163.22504426.v1","title":"Supplementary Figure S3. from Therapeutic Potential of Leelamine, a Novel Inhibitor of Androgen Receptor and Castration-Resistant Prostate Cancer","display_name":"Supplementary Figure S3. from Therapeutic Potential of Leelamine, a Novel Inhibitor of Androgen Receptor and Castration-Resistant Prostate Cancer","publication_year":2023,"publication_date":"2023-04-03","ids":{"openalex":"https://openalex.org/W4362494491","doi":"https://doi.org/10.1158/1535-7163.22504426.v1"},"language":"en","primary_location":{"id":"doi:10.1158/1535-7163.22504426.v1","doi":"https://doi.org/10.1158/1535-7163.22504426.v1","is_oa":true,"landing_page_url":"http://dx.doi.org/10.1158/1535-7163.22504426.v1","pdf_url":null,"source":null,"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"acceptedVersion","is_accepted":true,"is_published":false,"raw_source_name":"American Association for Cancer Research","raw_type":"posted-content"},"volume":null,"type":"supplementary-materials","indexed_in":["crossref"],"open_access":{"is_oa":true,"oa_status":"gold","oa_url":"http://dx.doi.org/10.1158/1535-7163.22504426.v1","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5081980683","display_name":"Krishna Beer Singh","orcid":"https://orcid.org/0000-0002-4052-4373","observed_orcids":["https://orcid.org/0000-0002-4052-4373"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Krishna B. Singh","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5069231811","display_name":"Xinhua Ji","orcid":"https://orcid.org/0000-0001-6942-1514","observed_orcids":["https://orcid.org/0000-0001-6942-1514"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Xinhua Ji","raw_affiliation_strings":[],"raw_orcid":"https://orcid.org/0000-0001-6942-1514","affiliations":[]},{"author_position":"last","author":{"id":"https://openalex.org/A5022304953","display_name":"Shivendra Vikram Singh","orcid":"https://orcid.org/0000-0002-3733-144X","observed_orcids":["https://orcid.org/0000-0002-3733-144X"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Shivendra V. Singh","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]}],"institutions":[],"countries_distinct_count":0,"institutions_distinct_count":0,"corresponding_author_ids":[],"corresponding_institution_ids":[],"apc_list":null,"apc_paid":null,"fwci":null,"has_fulltext":false,"cited_by_count":0,"citation_normalized_percentile":null,"cited_by_percentile_year":null,"biblio":{"volume":null,"issue":null,"first_page":null,"last_page":null},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10543","display_name":"Prostate Cancer Treatment and Research","score":0.9994999766349792,"subfield":{"id":"https://openalex.org/subfields/2740","display_name":"Pulmonary and Respiratory Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T10543","display_name":"Prostate Cancer Treatment and Research","score":0.9994999766349792,"subfield":{"id":"https://openalex.org/subfields/2740","display_name":"Pulmonary and Respiratory Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10570","display_name":"Drug Transport and Resistance Mechanisms","score":0.0,"subfield":{"id":"https://openalex.org/subfields/2730","display_name":"Oncology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T11146","display_name":"Hormonal and reproductive studies","score":0.0,"subfield":{"id":"https://openalex.org/subfields/2712","display_name":"Endocrinology, Diabetes and Metabolism"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/leelamine","display_name":"leelamine","score":0.9890000224113464},{"id":"https://openalex.org/keywords/androgen-receptor","display_name":"androgen receptor","score":0.9929999709129333},{"id":"https://openalex.org/keywords/ar-splice-variants","display_name":"androgen receptor splice variants","score":0.8579999804496765},{"id":"https://openalex.org/keywords/ar-v7","display_name":"AR-V7","score":0.9929999709129333},{"id":"https://openalex.org/keywords/castration-resistant-prostate-cancer","display_name":"castration-resistant prostate cancer","score":0.9070000052452087},{"id":"https://openalex.org/keywords/22rv1","display_name":"22Rv1 cells","score":0.9369999766349792},{"id":"https://openalex.org/keywords/lncap-cells","display_name":"LNCaP cells","score":0.9990000128746033},{"id":"https://openalex.org/keywords/c4-2b-cells","display_name":"C4-2B cells","score":0.9629999995231628},{"id":"https://openalex.org/keywords/androgen-receptor-inhibition","display_name":"androgen receptor inhibition","score":0.5659999847412109}],"concepts":[{"id":"https://openalex.org/C2780192828","wikidata":"https://www.wikidata.org/wiki/Q181257","display_name":"Prostate cancer","level":3,"score":0.810839056968689},{"id":"https://openalex.org/C2779256933","wikidata":"https://www.wikidata.org/wiki/Q58929","display_name":"Castration","level":3,"score":0.7495687007904053},{"id":"https://openalex.org/C61367390","wikidata":"https://www.wikidata.org/wiki/Q416601","display_name":"Androgen receptor","level":4,"score":0.6701436042785645},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.5325172543525696},{"id":"https://openalex.org/C2776235491","wikidata":"https://www.wikidata.org/wiki/Q9625","display_name":"Prostate","level":3,"score":0.46600064635276794},{"id":"https://openalex.org/C121608353","wikidata":"https://www.wikidata.org/wiki/Q12078","display_name":"Cancer","level":2,"score":0.4565233588218689},{"id":"https://openalex.org/C143998085","wikidata":"https://www.wikidata.org/wiki/Q162555","display_name":"Oncology","level":1,"score":0.40516600012779236},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.3962467908859253},{"id":"https://openalex.org/C71315377","wikidata":"https://www.wikidata.org/wiki/Q11364","display_name":"Hormone","level":2,"score":0.12637102603912354}],"mesh":[],"locations_count":2,"locations":[{"id":"doi:10.1158/1535-7163.22504426.v1","doi":"https://doi.org/10.1158/1535-7163.22504426.v1","is_oa":true,"landing_page_url":"http://dx.doi.org/10.1158/1535-7163.22504426.v1","pdf_url":null,"source":null,"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"acceptedVersion","is_accepted":true,"is_published":false,"raw_source_name":"American Association for Cancer Research","raw_type":"posted-content"},{"id":"pmh:oai:figshare.com:article/22504426","doi":null,"is_oa":true,"landing_page_url":"https://figshare.com/articles/journal_contribution/Supplementary_Figure_S3_from_Therapeutic_Potential_of_Leelamine_a_Novel_Inhibitor_of_Androgen_Receptor_and_Castration-Resistant_Prostate_Cancer/22504426","pdf_url":null,"source":{"id":"https://openalex.org/S4377196282","display_name":"Figshare","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I4210132348","host_organization_name":"Figshare (United Kingdom)","host_organization_lineage":["https://openalex.org/I4210132348"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"","raw_type":"Text"}],"best_oa_location":{"id":"doi:10.1158/1535-7163.22504426.v1","doi":"https://doi.org/10.1158/1535-7163.22504426.v1","is_oa":true,"landing_page_url":"http://dx.doi.org/10.1158/1535-7163.22504426.v1","pdf_url":null,"source":null,"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"acceptedVersion","is_accepted":true,"is_published":false,"raw_source_name":"American Association for Cancer Research","raw_type":"posted-content"},"sustainable_development_goals":[{"id":"https://metadata.un.org/sdg/3","score":0.8371999859809875,"display_name":"Good health and well-being"}],"study_designs":[],"awards":[],"funders":[],"has_content":{"grobid_xml":false,"pdf":false},"content_urls":null,"referenced_works_count":0,"referenced_works":[],"related_works":["https://openalex.org/W2883445005","https://openalex.org/W4362494568","https://openalex.org/W4361929394","https://openalex.org/W2475497292","https://openalex.org/W326158205","https://openalex.org/W2036584295","https://openalex.org/W2083926838","https://openalex.org/W2887668760","https://openalex.org/W2975892120","https://openalex.org/W1999343166"],"abstract_inverted_index":{"Densitometric":[0],"quantitation":[1],"of":[2,25],"immunoblots":[3],"for":[4],"AR,":[5],"AR":[6],"splice":[7],"variants,":[8],"AR-V7,":[9],"and":[10,16],"phospho-AR":[11],"(Ser213/210)":[12],"in":[13,22],"22Rv1,":[14],"LNCaP,":[15],"C4-2B":[17],"cells":[18],"(for":[19],"data":[20],"shown":[21],"Fig.":[23],"2A":[24],"the":[26],"main":[27],"text).":[28]},"counts_by_year":[],"updated_date":"2026-09-22T06:50:58.402377","created_date":"2023-04-05T00:00:00"}