{"id":"https://openalex.org/W4362493791","doi":"https://doi.org/10.1158/1541-7786.22512766","title":"Supplementary Data, Supplementary Figures S1-S9 from The Pioneering Role of GATA2 in Androgen Receptor Variant Regulation Is Controlled by Bromodomain and Extraterminal Proteins in Castrate-Resistant Prostate Cancer","display_name":"Supplementary Data, Supplementary Figures S1-S9 from The Pioneering Role of GATA2 in Androgen Receptor Variant Regulation Is Controlled by Bromodomain and Extraterminal Proteins in Castrate-Resistant Prostate Cancer","publication_year":2023,"publication_date":"2023-04-03","ids":{"openalex":"https://openalex.org/W4362493791","doi":"https://doi.org/10.1158/1541-7786.22512766"},"language":"en","primary_location":{"id":"doi:10.1158/1541-7786.22512766","doi":"https://doi.org/10.1158/1541-7786.22512766","is_oa":true,"landing_page_url":"http://dx.doi.org/10.1158/1541-7786.22512766","pdf_url":"https://aacr.figshare.com/ndownloader/files/39974785","source":null,"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"American Association for Cancer Research","raw_type":"posted-content"},"volume":null,"type":"supplementary-materials","is_traditional":false,"indexed_in":["crossref"],"open_access":{"is_oa":true,"oa_status":"gold","oa_url":"https://aacr.figshare.com/ndownloader/files/39974785","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5073978983","display_name":"Lewis Chaytor","orcid":"https://orcid.org/0009-0000-4231-0726","observed_orcids":["https://orcid.org/0009-0000-4231-0726"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Lewis Chaytor","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5021533016","display_name":"Matthew Simcock","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Matthew Simcock","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5080394398","display_name":"Sirintra Nakjang","orcid":"https://orcid.org/0000-0003-2960-6842","observed_orcids":["https://orcid.org/0000-0003-2960-6842"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Sirintra Nakjang","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5006487701","display_name":"Richard J. Heath","orcid":"https://orcid.org/0000-0002-1795-1254","observed_orcids":["https://orcid.org/0000-0002-1795-1254"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Richard Heath","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":null,"display_name":"Laura Walker","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Laura Walker","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5062478414","display_name":"Craig N. Robson","orcid":"https://orcid.org/0000-0002-9628-6669","observed_orcids":["https://orcid.org/0000-0002-9628-6669"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Craig Robson","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5100569836","display_name":"Dominic Jones","orcid":"https://orcid.org/0009-0005-0848-2387","observed_orcids":["https://orcid.org/0009-0005-0848-2387"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Dominic Jones","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"last","author":{"id":"https://openalex.org/A5062744941","display_name":"Luke Gaughan","orcid":"https://orcid.org/0000-0002-9330-7874","observed_orcids":["https://orcid.org/0000-0002-9330-7874"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Luke Gaughan","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]}],"institutions":[],"countries_distinct_count":0,"institutions_distinct_count":0,"corresponding_author_ids":[],"corresponding_institution_ids":[],"apc_list":null,"apc_paid":null,"fwci":null,"has_fulltext":true,"cited_by_count":0,"citation_normalized_percentile":null,"cited_by_percentile_year":null,"biblio":{"volume":null,"issue":null,"first_page":null,"last_page":null},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10543","display_name":"Prostate Cancer Treatment and Research","score":0.9965999722480774,"subfield":{"id":"https://openalex.org/subfields/1306","display_name":"Cancer Research"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T10543","display_name":"Prostate Cancer Treatment and Research","score":0.9965999722480774,"subfield":{"id":"https://openalex.org/subfields/1306","display_name":"Cancer Research"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T12820","display_name":"Chromatin Remodeling and Cancer","score":0.0013000000035390258,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T12534","display_name":"Protein Degradation and Inhibitors","score":0.000699999975040555,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/gata2","display_name":"GATA2","score":1.0},{"id":"https://openalex.org/keywords/ar-splice-variants","display_name":"androgen receptor splice variants","score":0.8939999938011169},{"id":"https://openalex.org/keywords/castration-resistant-prostate-cancer","display_name":"castration-resistant prostate cancer","score":0.906000018119812},{"id":"https://openalex.org/keywords/bet-proteins","display_name":"BET proteins","score":0.9909999966621399},{"id":"https://openalex.org/keywords/chromatin-occupancy","display_name":"chromatin occupancy","score":0.7279999852180481},{"id":"https://openalex.org/keywords/cistrome","display_name":"cistrome","score":0.5649999976158142},{"id":"https://openalex.org/keywords/splicing-regulation","display_name":"splicing regulation","score":0.7710000276565552},{"id":"https://openalex.org/keywords/gene-ontology","display_name":"Gene Ontology","score":0.4090000092983246}],"concepts":[{"id":"https://openalex.org/C74401373","wikidata":"https://www.wikidata.org/wiki/Q1829843","display_name":"Bromodomain","level":4,"score":0.8082988858222961},{"id":"https://openalex.org/C43821964","wikidata":"https://www.wikidata.org/wiki/Q18025461","display_name":"GATA2","level":4,"score":0.7952462434768677},{"id":"https://openalex.org/C2780192828","wikidata":"https://www.wikidata.org/wiki/Q181257","display_name":"Prostate cancer","level":3,"score":0.6021257638931274},{"id":"https://openalex.org/C162317418","wikidata":"https://www.wikidata.org/wiki/Q252857","display_name":"Transcriptome","level":4,"score":0.5046564340591431},{"id":"https://openalex.org/C502942594","wikidata":"https://www.wikidata.org/wiki/Q3421914","display_name":"Cancer research","level":1,"score":0.5003979206085205},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.4778708815574646},{"id":"https://openalex.org/C61367390","wikidata":"https://www.wikidata.org/wiki/Q416601","display_name":"Androgen receptor","level":4,"score":0.44482243061065674},{"id":"https://openalex.org/C154456304","wikidata":"https://www.wikidata.org/wiki/Q18027046","display_name":"FOXA1","level":4,"score":0.4299355745315552},{"id":"https://openalex.org/C83640560","wikidata":"https://www.wikidata.org/wiki/Q180951","display_name":"Chromatin","level":3,"score":0.4140147566795349},{"id":"https://openalex.org/C121608353","wikidata":"https://www.wikidata.org/wiki/Q12078","display_name":"Cancer","level":2,"score":0.37362873554229736},{"id":"https://openalex.org/C64927066","wikidata":"https://www.wikidata.org/wiki/Q36293","display_name":"Histone","level":3,"score":0.3647320568561554},{"id":"https://openalex.org/C54355233","wikidata":"https://www.wikidata.org/wiki/Q7162","display_name":"Genetics","level":1,"score":0.35643836855888367},{"id":"https://openalex.org/C104317684","wikidata":"https://www.wikidata.org/wiki/Q7187","display_name":"Gene","level":2,"score":0.3321990966796875},{"id":"https://openalex.org/C86339819","wikidata":"https://www.wikidata.org/wiki/Q407384","display_name":"Transcription factor","level":3,"score":0.2295677661895752},{"id":"https://openalex.org/C150194340","wikidata":"https://www.wikidata.org/wiki/Q26972","display_name":"Gene expression","level":3,"score":0.1792140007019043}],"mesh":[],"locations_count":3,"locations":[{"id":"doi:10.1158/1541-7786.22512766","doi":"https://doi.org/10.1158/1541-7786.22512766","is_oa":true,"landing_page_url":"http://dx.doi.org/10.1158/1541-7786.22512766","pdf_url":"https://aacr.figshare.com/ndownloader/files/39974785","source":null,"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"American Association for Cancer Research","raw_type":"posted-content"},{"id":"doi:10.1158/1541-7786.22512766.v1","doi":"https://doi.org/10.1158/1541-7786.22512766.v1","is_oa":true,"landing_page_url":"http://dx.doi.org/10.1158/1541-7786.22512766.v1","pdf_url":null,"source":null,"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"American Association for Cancer Research","raw_type":"posted-content"},{"id":"pmh:oai:figshare.com:article/22512766","doi":null,"is_oa":true,"landing_page_url":"https://figshare.com/articles/journal_contribution/Supplementary_Data_Supplementary_Figures_S1-S9_from_The_Pioneering_Role_of_GATA2_in_Androgen_Receptor_Variant_Regulation_Is_Controlled_by_Bromodomain_and_Extraterminal_Proteins_in_Castrate-Resistant_Prostate_Cancer/22512766","pdf_url":null,"source":{"id":"https://openalex.org/S4377196282","display_name":"Figshare","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I4210132348","host_organization_name":"Figshare (United Kingdom)","host_organization_lineage":["https://openalex.org/I4210132348"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"","raw_type":"Text"}],"best_oa_location":{"id":"doi:10.1158/1541-7786.22512766","doi":"https://doi.org/10.1158/1541-7786.22512766","is_oa":true,"landing_page_url":"http://dx.doi.org/10.1158/1541-7786.22512766","pdf_url":"https://aacr.figshare.com/ndownloader/files/39974785","source":null,"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"American Association for Cancer Research","raw_type":"posted-content"},"sustainable_development_goals":[{"display_name":"Good health and well-being","id":"https://metadata.un.org/sdg/3","score":0.5683000087738037}],"study_designs":[],"awards":[],"funders":[],"has_content":{"pdf":true,"grobid_xml":true},"content_urls":{"pdf":"https://content.openalex.org/works/W4362493791.pdf","grobid_xml":"https://content.openalex.org/works/W4362493791.grobid-xml"},"referenced_works_count":0,"referenced_works":[],"related_works":["https://openalex.org/W2919699700","https://openalex.org/W4362493428","https://openalex.org/W2059586182","https://openalex.org/W2062357159","https://openalex.org/W2741137833","https://openalex.org/W4306641994","https://openalex.org/W2103201026","https://openalex.org/W7066858205","https://openalex.org/W2601270378","https://openalex.org/W2470667884"],"abstract_inverted_index":{"S1:":[0],"GATA2":[1,16,20,28,34,49,54,63,69],"depletion":[2,17],"down-regulates":[3],"AR-V":[4,22,30],"target":[5],"genes":[6],"S2:":[7],"Chromatin":[8],"occupancy":[9],"of":[10,27,48,53,62],"AR-Vs":[11],"is":[12],"not":[13],"perturbed":[14],"by":[15],"S3:":[18],"Overlapping":[19,51],"and":[21,29,35,55,64],"transcriptomes":[23,31,67],"S4:":[24],"Gene":[25],"ontology":[26],"S5:":[32],"Assessing":[33,60],"BET":[36,56,65],"protein":[37],"interplay":[38],"in":[39,73],"prostate":[40,74],"cancer":[41,75],"cell":[42],"lines":[43],"S6:":[44],"Global":[45],"cistromic":[46],"analysis":[47],"S7:":[50],"cistromes":[52],"family":[57],"members":[58],"S8:":[59],"overlap":[61],"protein-regulated":[66],"S9:":[68],"regulates":[70],"splicing":[71],"activity":[72],"cells":[76]},"counts_by_year":[],"updated_date":"2026-11-09T13:22:03.289127","created_date":"2023-04-05T00:00:00"}