{"id":"https://openalex.org/W4362492472","doi":"https://doi.org/10.1158/1541-7786.22517662","title":"Supplementary Figure 2 from Interplay between Cytoplasmic and Nuclear Androgen Receptor Splice Variants Mediates Castration Resistance","display_name":"Supplementary Figure 2 from Interplay between Cytoplasmic and Nuclear Androgen Receptor Splice Variants Mediates Castration Resistance","publication_year":2023,"publication_date":"2023-04-03","ids":{"openalex":"https://openalex.org/W4362492472","doi":"https://doi.org/10.1158/1541-7786.22517662"},"language":"en","primary_location":{"id":"doi:10.1158/1541-7786.22517662","doi":"https://doi.org/10.1158/1541-7786.22517662","is_oa":true,"landing_page_url":"https://doi.org/10.1158/1541-7786.22517662","pdf_url":null,"source":null,"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"acceptedVersion","is_accepted":true,"is_published":false,"raw_source_name":"American Association for Cancer Research","raw_type":"posted-content"},"volume":null,"type":"supplementary-materials","indexed_in":["crossref"],"open_access":{"is_oa":true,"oa_status":"gold","oa_url":"https://doi.org/10.1158/1541-7786.22517662","any_repository_has_fulltext":null},"authorships":[{"author_position":"first","author":{"id":null,"display_name":"Yang Zhan","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Yang Zhan","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5103045488","display_name":"Guanyi Zhang","orcid":"https://orcid.org/0000-0002-7241-2325","observed_orcids":["https://orcid.org/0000-0002-7241-2325"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Guanyi Zhang","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5100351309","display_name":"Xiaojie Wang","orcid":"https://orcid.org/0000-0003-4817-5830","observed_orcids":["https://orcid.org/0000-0003-4817-5830"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Xiaojie Wang","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5100905164","display_name":"Yanfeng Qi","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Yanfeng Qi","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5110967604","display_name":"Shanshan Bai","orcid":"https://orcid.org/0000-0003-2439-6444","observed_orcids":["https://orcid.org/0000-0003-2439-6444"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Shanshan Bai","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5101614201","display_name":"Dongying Li","orcid":"https://orcid.org/0000-0003-0721-2500","observed_orcids":["https://orcid.org/0000-0003-0721-2500"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Dongying Li","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5054190396","display_name":"Tianfang Ma","orcid":"https://orcid.org/0000-0003-4161-882X","observed_orcids":["https://orcid.org/0000-0003-4161-882X"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Tianfang Ma","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5073246821","display_name":"Oliver A. Sartor","orcid":"https://orcid.org/0000-0002-8777-7343","observed_orcids":["https://orcid.org/0000-0002-8777-7343"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Oliver Sartor","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5002551784","display_name":"Erik K. Flemington","orcid":"https://orcid.org/0000-0003-0513-5281","observed_orcids":["https://orcid.org/0000-0003-0513-5281"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Erik K. Flemington","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5100454575","display_name":"Haitao Zhang","orcid":"https://orcid.org/0000-0002-1639-4089","observed_orcids":["https://orcid.org/0000-0002-1639-4089","https://orcid.org/0000-0002-1803-3148","https://orcid.org/0000-0001-5949-6483","https://orcid.org/0000-0002-1677-6132","https://orcid.org/0000-0002-4084-5150","https://orcid.org/0000-0003-4123-3102","https://orcid.org/0000-0001-5467-3428","https://orcid.org/0000-0001-7845-3331","https://orcid.org/0000-0002-2487-6694","https://orcid.org/0000-0002-5896-6487","https://orcid.org/0000-0003-4056-1999","https://orcid.org/0000-0003-4943-1859","https://orcid.org/0009-0001-1303-3384","https://orcid.org/0009-0004-6174-6364","https://orcid.org/0009-0005-3132-1338","https://orcid.org/0009-0006-5991-4976","https://orcid.org/0009-0007-9146-1265","https://orcid.org/0000-0001-7520-4209","https://orcid.org/0000-0001-7531-2525","https://orcid.org/0000-0001-7563-0283","https://orcid.org/0000-0001-7878-5707","https://orcid.org/0000-0001-7951-0502","https://orcid.org/0000-0001-8279-7903","https://orcid.org/0000-0001-8746-5588","https://orcid.org/0000-0001-9491-1953","https://orcid.org/0000-0001-9938-4179","https://orcid.org/0000-0002-0030-3234","https://orcid.org/0000-0002-1101-2766","https://orcid.org/0000-0002-1141-1150","https://orcid.org/0000-0002-1158-2806","https://orcid.org/0000-0002-1208-8199","https://orcid.org/0000-0002-1405-2843","https://orcid.org/0000-0002-1609-0501","https://orcid.org/0000-0002-2049-3485","https://orcid.org/0000-0002-2058-7123","https://orcid.org/0000-0002-2115-6317","https://orcid.org/0000-0002-2335-7884","https://orcid.org/0000-0002-2430-3845","https://orcid.org/0000-0002-2600-112X","https://orcid.org/0000-0002-3963-1331","https://orcid.org/0000-0002-4081-5752","https://orcid.org/0000-0002-4786-2113","https://orcid.org/0000-0002-5546-2347","https://orcid.org/0000-0002-5867-1478","https://orcid.org/0000-0002-6166-2089","https://orcid.org/0000-0002-6208-1622","https://orcid.org/0000-0002-6979-9020","https://orcid.org/0000-0002-7913-5228","https://orcid.org/0000-0002-7929-9003","https://orcid.org/0000-0002-8226-0695","https://orcid.org/0000-0002-8581-6898","https://orcid.org/0000-0002-8796-2178","https://orcid.org/0000-0002-9103-4796","https://orcid.org/0000-0002-9128-4357","https://orcid.org/0000-0002-9394-9383","https://orcid.org/0000-0002-9546-8524","https://orcid.org/0000-0003-0520-0821","https://orcid.org/0000-0003-0710-9351","https://orcid.org/0000-0003-1734-6051","https://orcid.org/0000-0003-2186-5508","https://orcid.org/0000-0003-2442-0045","https://orcid.org/0000-0003-2573-8848","https://orcid.org/0000-0003-3501-8385","https://orcid.org/0000-0003-4359-6839","https://orcid.org/0009-0000-0054-0689","https://orcid.org/0009-0000-5253-3624","https://orcid.org/0009-0000-6493-7917","https://orcid.org/0009-0000-7699-6703","https://orcid.org/0009-0000-9715-4484","https://orcid.org/0009-0001-0529-4592","https://orcid.org/0009-0001-4054-0875","https://orcid.org/0009-0001-7354-0265","https://orcid.org/0009-0001-8767-7174","https://orcid.org/0009-0001-9152-0225","https://orcid.org/0009-0001-9703-5060","https://orcid.org/0009-0001-9906-8296","https://orcid.org/0009-0002-0144-970X","https://orcid.org/0009-0002-2454-905X","https://orcid.org/0009-0002-5326-9612","https://orcid.org/0009-0002-6736-3159","https://orcid.org/0009-0002-8915-2360","https://orcid.org/0009-0003-0262-110X","https://orcid.org/0009-0003-0438-4961","https://orcid.org/0009-0003-4206-8441","https://orcid.org/0009-0003-4763-633X","https://orcid.org/0009-0003-5509-7858","https://orcid.org/0009-0003-7826-9579","https://orcid.org/0009-0004-1770-7536","https://orcid.org/0009-0004-9044-6942","https://orcid.org/0009-0005-0261-4211","https://orcid.org/0009-0005-4328-2102","https://orcid.org/0009-0005-5374-5836","https://orcid.org/0009-0005-8257-6760","https://orcid.org/0009-0006-0046-5459","https://orcid.org/0009-0006-0322-1521","https://orcid.org/0009-0006-0563-467X","https://orcid.org/0009-0006-1547-9335","https://orcid.org/0009-0006-1705-1703","https://orcid.org/0009-0006-2771-4494","https://orcid.org/0009-0006-3092-0539","https://orcid.org/0009-0006-8139-5092","https://orcid.org/0009-0006-8866-171X","https://orcid.org/0009-0007-0184-4773","https://orcid.org/0009-0007-3384-9739","https://orcid.org/0009-0007-4669-334X","https://orcid.org/0009-0007-6631-8010","https://orcid.org/0009-0007-6842-4618","https://orcid.org/0009-0007-9145-3919","https://orcid.org/0009-0008-0546-7327","https://orcid.org/0009-0008-2420-8515","https://orcid.org/0009-0008-6468-556X","https://orcid.org/0009-0008-7443-027X","https://orcid.org/0009-0008-9930-1968","https://orcid.org/0009-0009-1235-6462","https://orcid.org/0009-0009-1251-8281","https://orcid.org/0009-0009-2824-0042","https://orcid.org/0009-0009-4077-0468","https://orcid.org/0009-0009-8277-0546","https://orcid.org/0009-0002-5922-137X","https://orcid.org/0009-0009-9151-1546"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Haitao Zhang","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5009486201","display_name":"Peng Lee","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Peng Lee","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"last","author":{"id":"https://openalex.org/A5100650282","display_name":"Yan Dong","orcid":"https://orcid.org/0000-0002-4018-3839","observed_orcids":["https://orcid.org/0000-0002-4018-3839"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Yan Dong","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]}],"institutions":[],"countries_distinct_count":0,"institutions_distinct_count":0,"corresponding_author_ids":[],"corresponding_institution_ids":[],"apc_list":null,"apc_paid":null,"fwci":null,"has_fulltext":false,"cited_by_count":0,"citation_normalized_percentile":null,"cited_by_percentile_year":null,"biblio":{"volume":null,"issue":null,"first_page":null,"last_page":null},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10543","display_name":"Prostate Cancer Treatment and Research","score":0.9990000128746033,"subfield":{"id":"https://openalex.org/subfields/2740","display_name":"Pulmonary and Respiratory Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T10543","display_name":"Prostate Cancer Treatment and Research","score":0.9990000128746033,"subfield":{"id":"https://openalex.org/subfields/2740","display_name":"Pulmonary and Respiratory Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T12820","display_name":"Chromatin Remodeling and Cancer","score":9.999999747378752e-05,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10756","display_name":"Estrogen and related hormone effects","score":9.999999747378752e-05,"subfield":{"id":"https://openalex.org/subfields/1311","display_name":"Genetics"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/ar-splice-variants","display_name":"androgen receptor splice variants","score":0.9240000247955322},{"id":"https://openalex.org/keywords/castration-resistance","display_name":"castration resistance","score":0.8349999785423279},{"id":"https://openalex.org/keywords/nuclear-translocation","display_name":"nuclear translocation","score":0.9440000057220459},{"id":"https://openalex.org/keywords/androgen-receptor-transactivation","display_name":"androgen receptor transactivation","score":0.8259999752044678},{"id":"https://openalex.org/keywords/c4-2-cells","display_name":"C4-2 cells","score":0.9380000233650208},{"id":"https://openalex.org/keywords/prostate-cancer","display_name":"prostate cancer","score":0.8330000042915344}],"concepts":[{"id":"https://openalex.org/C61367390","wikidata":"https://www.wikidata.org/wiki/Q416601","display_name":"Androgen receptor","level":4,"score":0.8276624083518982},{"id":"https://openalex.org/C2780989783","wikidata":"https://www.wikidata.org/wiki/Q7578557","display_name":"splice","level":3,"score":0.7582974433898926},{"id":"https://openalex.org/C190062978","wikidata":"https://www.wikidata.org/wiki/Q79899","display_name":"Cytoplasm","level":2,"score":0.6247776746749878},{"id":"https://openalex.org/C2779256933","wikidata":"https://www.wikidata.org/wiki/Q58929","display_name":"Castration","level":3,"score":0.5228174924850464},{"id":"https://openalex.org/C2777911890","wikidata":"https://www.wikidata.org/wiki/Q62614","display_name":"Androgen","level":3,"score":0.5063086748123169},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.41737306118011475},{"id":"https://openalex.org/C57473165","wikidata":"https://www.wikidata.org/wiki/Q7315604","display_name":"Resistance (ecology)","level":2,"score":0.41335320472717285},{"id":"https://openalex.org/C95444343","wikidata":"https://www.wikidata.org/wiki/Q7141","display_name":"Cell biology","level":1,"score":0.3652108311653137},{"id":"https://openalex.org/C54355233","wikidata":"https://www.wikidata.org/wiki/Q7162","display_name":"Genetics","level":1,"score":0.29549312591552734},{"id":"https://openalex.org/C134018914","wikidata":"https://www.wikidata.org/wiki/Q162606","display_name":"Endocrinology","level":1,"score":0.20086997747421265},{"id":"https://openalex.org/C2780192828","wikidata":"https://www.wikidata.org/wiki/Q181257","display_name":"Prostate cancer","level":3,"score":0.18828144669532776},{"id":"https://openalex.org/C104317684","wikidata":"https://www.wikidata.org/wiki/Q7187","display_name":"Gene","level":2,"score":0.1579488217830658},{"id":"https://openalex.org/C71315377","wikidata":"https://www.wikidata.org/wiki/Q11364","display_name":"Hormone","level":2,"score":0.061049193143844604},{"id":"https://openalex.org/C18903297","wikidata":"https://www.wikidata.org/wiki/Q7150","display_name":"Ecology","level":1,"score":0.0},{"id":"https://openalex.org/C121608353","wikidata":"https://www.wikidata.org/wiki/Q12078","display_name":"Cancer","level":2,"score":0.0}],"mesh":[],"locations_count":1,"locations":[{"id":"doi:10.1158/1541-7786.22517662","doi":"https://doi.org/10.1158/1541-7786.22517662","is_oa":true,"landing_page_url":"https://doi.org/10.1158/1541-7786.22517662","pdf_url":null,"source":null,"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"acceptedVersion","is_accepted":true,"is_published":false,"raw_source_name":"American Association for Cancer Research","raw_type":"posted-content"}],"best_oa_location":{"id":"doi:10.1158/1541-7786.22517662","doi":"https://doi.org/10.1158/1541-7786.22517662","is_oa":true,"landing_page_url":"https://doi.org/10.1158/1541-7786.22517662","pdf_url":null,"source":null,"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"acceptedVersion","is_accepted":true,"is_published":false,"raw_source_name":"American Association for Cancer Research","raw_type":"posted-content"},"sustainable_development_goals":[{"id":"https://metadata.un.org/sdg/3","score":0.6240000128746033,"display_name":"Good health and well-being"}],"sustainable_development_goals_aurora":[{"id":"https://metadata.un.org/sdg/2","score":0.5,"display_name":"Zero hunger"}],"study_designs":[],"awards":[],"funders":[],"has_content":{"pdf":false,"grobid_xml":false},"content_urls":null,"referenced_works_count":0,"referenced_works":[],"related_works":["https://openalex.org/W2169608764","https://openalex.org/W2033566079","https://openalex.org/W2327862400","https://openalex.org/W2017700331","https://openalex.org/W3009569511","https://openalex.org/W2365928272","https://openalex.org/W2095348706","https://openalex.org/W2051020921","https://openalex.org/W1967664125","https://openalex.org/W2012986564"],"abstract_inverted_index":{"S2.":[0],"AR-V4/V6":[1],"nuclear":[2],"translocation":[3],"leads":[4],"to":[5],"induced":[6],"AR":[7],"transactivation":[8],"in":[9],"C4-2":[10],"cells.":[11]},"counts_by_year":[],"updated_date":"2026-10-26T11:51:55.731654","created_date":"2023-04-05T00:00:00"}