{"id":"https://openalex.org/W4362484538","doi":"https://doi.org/10.1158/1940-6207.22526865","title":"Supplementary Figure 1 from Effects of Pubertal Exposure to Dietary Soy on Estrogen Receptor Activity in the Breast of Cynomolgus Macaques","display_name":"Supplementary Figure 1 from Effects of Pubertal Exposure to Dietary Soy on Estrogen Receptor Activity in the Breast of Cynomolgus Macaques","publication_year":2023,"publication_date":"2023-04-03","ids":{"openalex":"https://openalex.org/W4362484538","doi":"https://doi.org/10.1158/1940-6207.22526865"},"language":"en","primary_location":{"id":"doi:10.1158/1940-6207.22526865","doi":"https://doi.org/10.1158/1940-6207.22526865","is_oa":true,"landing_page_url":"http://dx.doi.org/10.1158/1940-6207.22526865","pdf_url":null,"source":null,"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"acceptedVersion","is_accepted":true,"is_published":false,"raw_source_name":"American Association for Cancer Research","raw_type":"posted-content"},"volume":null,"type":"supplementary-materials","indexed_in":["crossref"],"open_access":{"is_oa":true,"oa_status":"gold","oa_url":"http://dx.doi.org/10.1158/1940-6207.22526865","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5003264909","display_name":"Fitriya N. Dewi","orcid":"https://orcid.org/0000-0002-7908-7879","observed_orcids":["https://orcid.org/0000-0002-7908-7879"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Fitriya N. Dewi","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":null,"display_name":"Charles E. Wood","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Charles E. Wood","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5028732744","display_name":"Cynthia J. Willson","orcid":"https://orcid.org/0000-0003-0942-3723","observed_orcids":["https://orcid.org/0000-0003-0942-3723"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Cynthia J. Willson","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5071573042","display_name":"Thomas C. Register","orcid":"https://orcid.org/0000-0002-4078-0166","observed_orcids":["https://orcid.org/0000-0002-4078-0166"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Thomas C. Register","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5111792831","display_name":"Cynthia J. Lees","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Cynthia J. Lees","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5028659405","display_name":"Timothy D. Howard","orcid":"https://orcid.org/0000-0003-2518-4902","observed_orcids":["https://orcid.org/0000-0003-2518-4902"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Timothy D. Howard","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5014633542","display_name":"Zhiqing Huang","orcid":"https://orcid.org/0000-0001-5092-9297","observed_orcids":["https://orcid.org/0000-0001-5092-9297"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Zhiqing Huang","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5090233781","display_name":"Susan K. Murphy","orcid":"https://orcid.org/0000-0001-8298-7272","observed_orcids":["https://orcid.org/0000-0001-8298-7272"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Susan K. Murphy","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5006007842","display_name":"Janet Austin Tooze","orcid":"https://orcid.org/0000-0002-5160-0407","observed_orcids":["https://orcid.org/0000-0002-5160-0407"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Janet A. Tooze","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5113170997","display_name":"Jeff W. Chou","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Jeff W. Chou","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5024804165","display_name":"Lance David Miller","orcid":"https://orcid.org/0000-0003-3799-2528","observed_orcids":["https://orcid.org/0000-0003-3799-2528"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Lance D. Miller","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"last","author":{"id":"https://openalex.org/A5068860618","display_name":"J. Mark Cline","orcid":"https://orcid.org/0000-0003-4844-1238","observed_orcids":["https://orcid.org/0000-0003-4844-1238"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"J. Mark Cline","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]}],"institutions":[],"countries_distinct_count":0,"institutions_distinct_count":0,"corresponding_author_ids":[],"corresponding_institution_ids":[],"apc_list":null,"apc_paid":null,"fwci":null,"has_fulltext":false,"cited_by_count":0,"citation_normalized_percentile":null,"cited_by_percentile_year":null,"biblio":{"volume":null,"issue":null,"first_page":null,"last_page":null},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T11318","display_name":"Phytoestrogen effects and research","score":0.9994999766349792,"subfield":{"id":"https://openalex.org/subfields/2734","display_name":"Pathology and Forensic Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T11318","display_name":"Phytoestrogen effects and research","score":0.9994999766349792,"subfield":{"id":"https://openalex.org/subfields/2734","display_name":"Pathology and Forensic Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10756","display_name":"Estrogen and related hormone effects","score":0.00019999999494757503,"subfield":{"id":"https://openalex.org/subfields/1311","display_name":"Genetics"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10686","display_name":"Effects and risks of endocrine disrupting chemicals","score":9.999999747378752e-05,"subfield":{"id":"https://openalex.org/subfields/2307","display_name":"Health, Toxicology and Mutagenesis"},"field":{"id":"https://openalex.org/fields/23","display_name":"Environmental Science"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/dietary-soy","display_name":"dietary soy","score":0.9259999990463257},{"id":"https://openalex.org/keywords/pubertal-exposure","display_name":"pubertal exposure","score":0.8180000185966492},{"id":"https://openalex.org/keywords/estrogen-receptor-activity","display_name":"estrogen receptor activity","score":0.8870000243186951},{"id":"https://openalex.org/keywords/breast","display_name":"breast","score":0.6320000290870667},{"id":"https://openalex.org/keywords/isoflavonoids","display_name":"isoflavonoids","score":0.9100000262260437},{"id":"https://openalex.org/keywords/genistein","display_name":"genistein","score":0.9850000143051147},{"id":"https://openalex.org/keywords/daidzein","display_name":"daidzein","score":1.0},{"id":"https://openalex.org/keywords/equol","display_name":"equol","score":1.0},{"id":"https://openalex.org/keywords/endocrine-disruptors","display_name":"endocrine disruptors","score":0.5830000042915344}],"concepts":[{"id":"https://openalex.org/C2778379183","wikidata":"https://www.wikidata.org/wiki/Q3234924","display_name":"Isoflavonoid","level":4,"score":0.9682708978652954},{"id":"https://openalex.org/C2780955279","wikidata":"https://www.wikidata.org/wiki/Q408732","display_name":"Daidzein","level":3,"score":0.9394087195396423},{"id":"https://openalex.org/C2781262405","wikidata":"https://www.wikidata.org/wiki/Q5384747","display_name":"Equol","level":4,"score":0.8745324611663818},{"id":"https://openalex.org/C2778298627","wikidata":"https://www.wikidata.org/wiki/Q415957","display_name":"Genistein","level":2,"score":0.8664823770523071},{"id":"https://openalex.org/C2910376424","wikidata":"https://www.wikidata.org/wiki/Q11006","display_name":"SOY ISOFLAVONES","level":3,"score":0.6990501880645752},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.6216467618942261},{"id":"https://openalex.org/C84606932","wikidata":"https://www.wikidata.org/wiki/Q416496","display_name":"Estrogen receptor","level":4,"score":0.5675553679466248},{"id":"https://openalex.org/C2778270713","wikidata":"https://www.wikidata.org/wiki/Q414496","display_name":"Phytoestrogens","level":3,"score":0.5593199133872986},{"id":"https://openalex.org/C134018914","wikidata":"https://www.wikidata.org/wiki/Q162606","display_name":"Endocrinology","level":1,"score":0.5546377301216125},{"id":"https://openalex.org/C2777164284","wikidata":"https://www.wikidata.org/wiki/Q277954","display_name":"Estrogen","level":2,"score":0.5130470991134644},{"id":"https://openalex.org/C185592680","wikidata":"https://www.wikidata.org/wiki/Q2329","display_name":"Chemistry","level":0,"score":0.5078480839729309},{"id":"https://openalex.org/C31903555","wikidata":"https://www.wikidata.org/wiki/Q1637030","display_name":"Food science","level":1,"score":0.3370729088783264},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.2627025246620178},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.25583064556121826},{"id":"https://openalex.org/C2779054382","wikidata":"https://www.wikidata.org/wiki/Q72185287","display_name":"Flavonoid","level":3,"score":0.1915062665939331},{"id":"https://openalex.org/C55493867","wikidata":"https://www.wikidata.org/wiki/Q7094","display_name":"Biochemistry","level":1,"score":0.1612221896648407},{"id":"https://openalex.org/C530470458","wikidata":"https://www.wikidata.org/wiki/Q128581","display_name":"Breast cancer","level":3,"score":0.13676896691322327},{"id":"https://openalex.org/C121608353","wikidata":"https://www.wikidata.org/wiki/Q12078","display_name":"Cancer","level":2,"score":0.07098683714866638},{"id":"https://openalex.org/C2778004101","wikidata":"https://www.wikidata.org/wiki/Q133948","display_name":"Antioxidant","level":2,"score":0.0}],"mesh":[],"locations_count":3,"locations":[{"id":"doi:10.1158/1940-6207.22526865","doi":"https://doi.org/10.1158/1940-6207.22526865","is_oa":true,"landing_page_url":"http://dx.doi.org/10.1158/1940-6207.22526865","pdf_url":null,"source":null,"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"acceptedVersion","is_accepted":true,"is_published":false,"raw_source_name":"American Association for Cancer Research","raw_type":"posted-content"},{"id":"doi:10.1158/1940-6207.22526865.v1","doi":"https://doi.org/10.1158/1940-6207.22526865.v1","is_oa":true,"landing_page_url":"https://doi.org/10.1158/1940-6207.22526865.v1","pdf_url":"https://aacr.figshare.com/articles/journal_contribution/Supplementary_Figure_1_from_Effects_of_Pubertal_Exposure_to_Dietary_Soy_on_Estrogen_Receptor_Activity_in_the_Breast_of_Cynomolgus_Macaques/22526865/1/files/39989730.pdf","source":null,"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"acceptedVersion","is_accepted":true,"is_published":false,"raw_source_name":"American Association for Cancer Research","raw_type":"posted-content"},{"id":"pmh:oai:figshare.com:article/22526865","doi":null,"is_oa":true,"landing_page_url":"https://figshare.com/articles/journal_contribution/Supplementary_Figure_1_from_Effects_of_Pubertal_Exposure_to_Dietary_Soy_on_Estrogen_Receptor_Activity_in_the_Breast_of_Cynomolgus_Macaques/22526865","pdf_url":null,"source":{"id":"https://openalex.org/S4377196282","display_name":"Figshare","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I4210132348","host_organization_name":"Figshare (United Kingdom)","host_organization_lineage":["https://openalex.org/I4210132348"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"","raw_type":"Text"}],"best_oa_location":{"id":"doi:10.1158/1940-6207.22526865","doi":"https://doi.org/10.1158/1940-6207.22526865","is_oa":true,"landing_page_url":"http://dx.doi.org/10.1158/1940-6207.22526865","pdf_url":null,"source":null,"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"acceptedVersion","is_accepted":true,"is_published":false,"raw_source_name":"American Association for Cancer Research","raw_type":"posted-content"},"sustainable_development_goals":[{"id":"https://metadata.un.org/sdg/2","display_name":"Zero hunger","score":0.8409000039100647},{"id":"https://metadata.un.org/sdg/3","display_name":"Good health and well-being","score":0.5683000087738037}],"study_designs":[],"awards":[],"funders":[],"has_content":{"pdf":true,"grobid_xml":false},"content_urls":{"pdf":"https://content.openalex.org/works/W4362484538.pdf"},"referenced_works_count":0,"referenced_works":[],"related_works":["https://openalex.org/W2110115324","https://openalex.org/W4362568005","https://openalex.org/W2083905479","https://openalex.org/W2310580923","https://openalex.org/W2466002082","https://openalex.org/W2001444614","https://openalex.org/W4392701421","https://openalex.org/W2121554827","https://openalex.org/W2146029421","https://openalex.org/W2341181413"],"abstract_inverted_index":{"Serum":[0],"isoflavonoid":[1],"concentrations":[2],"across":[3],"the":[4,40],"pubertal":[5],"transition.":[6],"Levels":[7],"of":[8],"circulating":[9],"total":[10],"isoflavonoids":[11],"(genistein":[12],"+":[13,15],"daidzein":[14],"equol)":[16],"were":[17],"significantly":[18],"higher":[19],"in":[20,39],"soy-fed":[21],"monkeys.":[22],"Values":[23],"represent":[24],"LSMs":[25],"for":[26],"n=11-17":[27],"monkeys/group":[28],"(bars":[29],"=":[30],"SEM).":[31],"Significant":[32],"main":[33],"effects":[34],"and":[35],"interactions":[36],"are":[37],"indicated":[38],"panel.":[41]},"counts_by_year":[],"updated_date":"2026-11-04T10:54:05.112534","created_date":"2023-04-05T00:00:00"}