{"id":"https://openalex.org/W4362482672","doi":"https://doi.org/10.1158/2159-8290.22530177","title":"Supplementary Figure S3 from Mutant KRAS\u2013Induced Expression of ICAM-1 in Pancreatic Acinar Cells Causes Attraction of Macrophages to Expedite the Formation of Precancerous Lesions","display_name":"Supplementary Figure S3 from Mutant KRAS\u2013Induced Expression of ICAM-1 in Pancreatic Acinar Cells Causes Attraction of Macrophages to Expedite the Formation of Precancerous Lesions","publication_year":2023,"publication_date":"2023-04-03","ids":{"openalex":"https://openalex.org/W4362482672","doi":"https://doi.org/10.1158/2159-8290.22530177"},"language":"en","primary_location":{"id":"doi:10.1158/2159-8290.22530177","doi":"https://doi.org/10.1158/2159-8290.22530177","is_oa":true,"landing_page_url":"https://doi.org/10.1158/2159-8290.22530177","pdf_url":null,"source":null,"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"acceptedVersion","is_accepted":true,"is_published":false,"raw_source_name":"American Association for Cancer Research","raw_type":"posted-content"},"volume":null,"type":"supplementary-materials","indexed_in":["crossref"],"open_access":{"is_oa":true,"oa_status":"gold","oa_url":"https://doi.org/10.1158/2159-8290.22530177","any_repository_has_fulltext":null},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5019543378","display_name":"Geou\u2010Yarh Liou","orcid":"https://orcid.org/0000-0003-2728-3752","observed_orcids":["https://orcid.org/0000-0003-2728-3752"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Geou-Yarh Liou","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5062388236","display_name":"Heike R. D\u00f6ppler","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Heike D\u00f6ppler","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5038191637","display_name":"Brian M. Necela","orcid":"https://orcid.org/0000-0002-4409-1245","observed_orcids":["https://orcid.org/0000-0002-4409-1245"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Brian Necela","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5063883874","display_name":"Brandy H. Edenfield","orcid":"https://orcid.org/0009-0005-5571-9500","observed_orcids":["https://orcid.org/0009-0005-5571-9500"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Brandy Edenfield","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5100663891","display_name":"Lizhi Zhang","orcid":"https://orcid.org/0000-0001-5829-9234","observed_orcids":["https://orcid.org/0000-0001-5829-9234"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Lizhi Zhang","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5042354527","display_name":"David W. Dawson","orcid":"https://orcid.org/0000-0002-0215-5861","observed_orcids":["https://orcid.org/0000-0002-0215-5861"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"David W. Dawson","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"last","author":{"id":"https://openalex.org/A5064581175","display_name":"Peter St\u00f6rz","orcid":"https://orcid.org/0000-0002-0132-5128","observed_orcids":["https://orcid.org/0000-0002-0132-5128"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Peter Storz","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]}],"institutions":[],"countries_distinct_count":0,"institutions_distinct_count":0,"corresponding_author_ids":[],"corresponding_institution_ids":[],"apc_list":null,"apc_paid":null,"fwci":null,"has_fulltext":false,"cited_by_count":0,"citation_normalized_percentile":null,"cited_by_percentile_year":null,"biblio":{"volume":null,"issue":null,"first_page":null,"last_page":null},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10231","display_name":"Pancreatic and Hepatic Oncology Research","score":0.9932000041007996,"subfield":{"id":"https://openalex.org/subfields/2730","display_name":"Oncology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T10231","display_name":"Pancreatic and Hepatic Oncology Research","score":0.9932000041007996,"subfield":{"id":"https://openalex.org/subfields/2730","display_name":"Oncology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10760","display_name":"Pancreatitis Pathology and Treatment","score":0.00139999995008111,"subfield":{"id":"https://openalex.org/subfields/2746","display_name":"Surgery"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10839","display_name":"Pancreatic function and diabetes","score":0.0007999999797903001,"subfield":{"id":"https://openalex.org/subfields/2746","display_name":"Surgery"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/kras-mutation","display_name":"KRAS mutation","score":0.921999990940094},{"id":"https://openalex.org/keywords/icam-1","display_name":"ICAM-1","score":0.9769999980926514},{"id":"https://openalex.org/keywords/pancreatic-acinar-cells","display_name":"pancreatic acinar cells","score":0.9850000143051147},{"id":"https://openalex.org/keywords/pancreatic-intraepithelial-neoplasia","display_name":"pancreatic intraepithelial neoplasia","score":0.8799999952316284},{"id":"https://openalex.org/keywords/precancerous-lesions","display_name":"precancerous lesions","score":0.8629999756813049},{"id":"https://openalex.org/keywords/microvascularization","display_name":"microvascularization","score":0.9089999794960022},{"id":"https://openalex.org/keywords/alcian-blue-staining","display_name":"Alcian blue staining","score":0.9340000152587891}],"concepts":[{"id":"https://openalex.org/C143065580","wikidata":"https://www.wikidata.org/wiki/Q3285695","display_name":"Mutant","level":3,"score":0.6790286302566528},{"id":"https://openalex.org/C2781187634","wikidata":"https://www.wikidata.org/wiki/Q20969980","display_name":"KRAS","level":4,"score":0.6646010875701904},{"id":"https://openalex.org/C153911025","wikidata":"https://www.wikidata.org/wiki/Q7202","display_name":"Molecular biology","level":1,"score":0.5814613699913025},{"id":"https://openalex.org/C74864618","wikidata":"https://www.wikidata.org/wiki/Q2332446","display_name":"Staining","level":2,"score":0.4950813353061676},{"id":"https://openalex.org/C185946421","wikidata":"https://www.wikidata.org/wiki/Q3146527","display_name":"ICAM-1","level":3,"score":0.43557676672935486},{"id":"https://openalex.org/C185592680","wikidata":"https://www.wikidata.org/wiki/Q2329","display_name":"Chemistry","level":0,"score":0.3939322531223297},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.3691955804824829},{"id":"https://openalex.org/C95444343","wikidata":"https://www.wikidata.org/wiki/Q7141","display_name":"Cell biology","level":1,"score":0.30658766627311707},{"id":"https://openalex.org/C501734568","wikidata":"https://www.wikidata.org/wiki/Q42918","display_name":"Mutation","level":3,"score":0.2361680269241333},{"id":"https://openalex.org/C104317684","wikidata":"https://www.wikidata.org/wiki/Q7187","display_name":"Gene","level":2,"score":0.18917971849441528},{"id":"https://openalex.org/C54355233","wikidata":"https://www.wikidata.org/wiki/Q7162","display_name":"Genetics","level":1,"score":0.17408618330955505},{"id":"https://openalex.org/C55493867","wikidata":"https://www.wikidata.org/wiki/Q7094","display_name":"Biochemistry","level":1,"score":0.16644197702407837},{"id":"https://openalex.org/C79879829","wikidata":"https://www.wikidata.org/wiki/Q5571762","display_name":"Intracellular","level":2,"score":0.0}],"mesh":[],"locations_count":1,"locations":[{"id":"doi:10.1158/2159-8290.22530177","doi":"https://doi.org/10.1158/2159-8290.22530177","is_oa":true,"landing_page_url":"https://doi.org/10.1158/2159-8290.22530177","pdf_url":null,"source":null,"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"acceptedVersion","is_accepted":true,"is_published":false,"raw_source_name":"American Association for Cancer Research","raw_type":"posted-content"}],"best_oa_location":{"id":"doi:10.1158/2159-8290.22530177","doi":"https://doi.org/10.1158/2159-8290.22530177","is_oa":true,"landing_page_url":"https://doi.org/10.1158/2159-8290.22530177","pdf_url":null,"source":null,"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"acceptedVersion","is_accepted":true,"is_published":false,"raw_source_name":"American Association for Cancer Research","raw_type":"posted-content"},"sustainable_development_goals":[{"score":0.8371999859809875,"display_name":"Good health and well-being","id":"https://metadata.un.org/sdg/3"}],"study_designs":[],"awards":[],"funders":[],"has_content":{"grobid_xml":false,"pdf":false},"content_urls":null,"referenced_works_count":0,"referenced_works":[],"related_works":["https://openalex.org/W4362482562","https://openalex.org/W2107748627","https://openalex.org/W1677380074","https://openalex.org/W2185586482","https://openalex.org/W2105387520","https://openalex.org/W2563975489","https://openalex.org/W2022389076","https://openalex.org/W2221082133","https://openalex.org/W4255239467","https://openalex.org/W4393054192"],"abstract_inverted_index":{"Supplementary":[0],"Figure":[1],"S3":[2],"shows":[3],"analysis":[4],"for":[5],"microvascularization":[6],"(A),":[7],"alcian":[8],"blue":[9],"staining":[10],"of":[11],"tissue":[12],"sections":[13],"(B),":[14],"and":[15],"ICAM-1":[16],"expression":[17],"in":[18],"human":[19],"samples":[20],"(C).":[21]},"counts_by_year":[],"updated_date":"2026-09-22T06:50:58.402377","created_date":"2023-04-05T00:00:00"}