{"id":"https://openalex.org/W4362425592","doi":"https://doi.org/10.1158/1078-0432.22439788.v1","title":"Supplementary Figure S1 from BMS-536924 Reverses IGF-IR-Induced Transformation of Mammary Epithelial Cells and Causes Growth Inhibition and Polarization of MCF7 Cells","display_name":"Supplementary Figure S1 from BMS-536924 Reverses IGF-IR-Induced Transformation of Mammary Epithelial Cells and Causes Growth Inhibition and Polarization of MCF7 Cells","publication_year":2023,"publication_date":"2023-03-31","ids":{"openalex":"https://openalex.org/W4362425592","doi":"https://doi.org/10.1158/1078-0432.22439788.v1"},"language":"en","primary_location":{"id":"doi:10.1158/1078-0432.22439788.v1","doi":"https://doi.org/10.1158/1078-0432.22439788.v1","is_oa":true,"landing_page_url":"http://dx.doi.org/10.1158/1078-0432.22439788.v1","pdf_url":null,"source":null,"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"acceptedVersion","is_accepted":true,"is_published":false,"raw_source_name":"American Association for Cancer Research","raw_type":"posted-content"},"volume":null,"type":"supplementary-materials","indexed_in":["crossref"],"open_access":{"is_oa":true,"oa_status":"gold","oa_url":"http://dx.doi.org/10.1158/1078-0432.22439788.v1","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5077225386","display_name":"Beate C. Litzenburger","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Beate C. Litzenburger","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5100436425","display_name":"Hyun Jung Kim","orcid":"https://orcid.org/0009-0002-3589-5847","observed_orcids":["https://orcid.org/0009-0002-3589-5847"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Hyun-Jung Kim","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5022210435","display_name":"Isere Kuiatse","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Isere Kuiatse","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5088565265","display_name":"Joan M. Carboni","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Joan M. Carboni","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5055963089","display_name":"Ricardo M. Attar","orcid":"https://orcid.org/0000-0002-6942-8019","observed_orcids":["https://orcid.org/0000-0002-6942-8019"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Ricardo M. Attar","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5040094376","display_name":"Marco M. Gottardis","orcid":"https://orcid.org/0000-0003-2280-8708","observed_orcids":["https://orcid.org/0000-0003-2280-8708"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Marco M. Gottardis","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5111793100","display_name":"Craig R. Fairchild","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Craig R. Fairchild","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"last","author":{"id":"https://openalex.org/A5041977512","display_name":"Adrian V. Lee","orcid":"https://orcid.org/0000-0001-9917-514X","observed_orcids":["https://orcid.org/0000-0001-9917-514X"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Adrian V. Lee","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]}],"institutions":[],"countries_distinct_count":0,"institutions_distinct_count":0,"corresponding_author_ids":[],"corresponding_institution_ids":[],"apc_list":null,"apc_paid":null,"fwci":null,"has_fulltext":true,"cited_by_count":0,"citation_normalized_percentile":null,"cited_by_percentile_year":null,"biblio":{"volume":null,"issue":null,"first_page":null,"last_page":null},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10748","display_name":"Growth Hormone and Insulin-like Growth Factors","score":0.9955999851226807,"subfield":{"id":"https://openalex.org/subfields/2712","display_name":"Endocrinology, Diabetes and Metabolism"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T10748","display_name":"Growth Hormone and Insulin-like Growth Factors","score":0.9955999851226807,"subfield":{"id":"https://openalex.org/subfields/2712","display_name":"Endocrinology, Diabetes and Metabolism"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10952","display_name":"PI3K/AKT/mTOR signaling in cancer","score":0.0005000000237487257,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10756","display_name":"Estrogen and related hormone effects","score":0.0005000000237487257,"subfield":{"id":"https://openalex.org/subfields/1311","display_name":"Genetics"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/bms-536924","display_name":"BMS-536924","score":1.0},{"id":"https://openalex.org/keywords/igf-1-receptor","display_name":"IGF-1 receptor","score":0.9300000071525574},{"id":"https://openalex.org/keywords/mammary-epithelial-cells","display_name":"mammary epithelial cells","score":0.9879999756813049},{"id":"https://openalex.org/keywords/cell-transformation","display_name":"cell transformation","score":0.7269999980926514},{"id":"https://openalex.org/keywords/growth-inhibition","display_name":"growth inhibition","score":0.6970000267028809},{"id":"https://openalex.org/keywords/mcf-7-cells","display_name":"MCF-7 cells","score":0.8460000157356262},{"id":"https://openalex.org/keywords/cell-polarization","display_name":"cell polarization","score":0.609000027179718},{"id":"https://openalex.org/keywords/breast-cancer","display_name":"breast cancer","score":0.7020000219345093}],"concepts":[{"id":"https://openalex.org/C2779707156","wikidata":"https://www.wikidata.org/wiki/Q5611758","display_name":"Growth inhibition","level":3,"score":0.5373182892799377},{"id":"https://openalex.org/C502942594","wikidata":"https://www.wikidata.org/wiki/Q3421914","display_name":"Cancer research","level":1,"score":0.5300680994987488},{"id":"https://openalex.org/C204241405","wikidata":"https://www.wikidata.org/wiki/Q461499","display_name":"Transformation (genetics)","level":3,"score":0.5025155544281006},{"id":"https://openalex.org/C185592680","wikidata":"https://www.wikidata.org/wiki/Q2329","display_name":"Chemistry","level":0,"score":0.4750647246837616},{"id":"https://openalex.org/C205049153","wikidata":"https://www.wikidata.org/wiki/Q2698605","display_name":"Polarization (electrochemistry)","level":2,"score":0.45815834403038025},{"id":"https://openalex.org/C95444343","wikidata":"https://www.wikidata.org/wiki/Q7141","display_name":"Cell biology","level":1,"score":0.41001763939857483},{"id":"https://openalex.org/C62112901","wikidata":"https://www.wikidata.org/wiki/Q189159","display_name":"Cell growth","level":2,"score":0.3932134509086609},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.33209842443466187},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.2635318636894226},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.2565663158893585},{"id":"https://openalex.org/C104317684","wikidata":"https://www.wikidata.org/wiki/Q7187","display_name":"Gene","level":2,"score":0.07683193683624268},{"id":"https://openalex.org/C55493867","wikidata":"https://www.wikidata.org/wiki/Q7094","display_name":"Biochemistry","level":1,"score":0.07521983981132507},{"id":"https://openalex.org/C147789679","wikidata":"https://www.wikidata.org/wiki/Q11372","display_name":"Physical chemistry","level":1,"score":0.0}],"mesh":[],"locations_count":2,"locations":[{"id":"doi:10.1158/1078-0432.22439788.v1","doi":"https://doi.org/10.1158/1078-0432.22439788.v1","is_oa":true,"landing_page_url":"http://dx.doi.org/10.1158/1078-0432.22439788.v1","pdf_url":null,"source":null,"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"acceptedVersion","is_accepted":true,"is_published":false,"raw_source_name":"American Association for Cancer Research","raw_type":"posted-content"},{"id":"pmh:oai:figshare.com:article/22439788","doi":null,"is_oa":true,"landing_page_url":"https://figshare.com/articles/journal_contribution/Supplementary_Figure_S1_from_BMS-536924_Reverses_IGF-IR-Induced_Transformation_of_Mammary_Epithelial_Cells_and_Causes_Growth_Inhibition_and_Polarization_of_MCF7_Cells/22439788","pdf_url":null,"source":{"id":"https://openalex.org/S4377196282","display_name":"Figshare","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I4210132348","host_organization_name":"Figshare (United Kingdom)","host_organization_lineage":["https://openalex.org/I4210132348"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"","raw_type":"Text"}],"best_oa_location":{"id":"doi:10.1158/1078-0432.22439788.v1","doi":"https://doi.org/10.1158/1078-0432.22439788.v1","is_oa":true,"landing_page_url":"http://dx.doi.org/10.1158/1078-0432.22439788.v1","pdf_url":null,"source":null,"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"acceptedVersion","is_accepted":true,"is_published":false,"raw_source_name":"American Association for Cancer Research","raw_type":"posted-content"},"sustainable_development_goals":[{"score":0.5683000087738037,"display_name":"Good health and well-being","id":"https://metadata.un.org/sdg/3"}],"sustainable_development_goals_aurora":[{"score":0.4699999988079071,"display_name":"Zero hunger","id":"https://metadata.un.org/sdg/2"}],"study_designs":[],"awards":[],"funders":[],"has_content":{"grobid_xml":false,"pdf":false},"content_urls":null,"referenced_works_count":0,"referenced_works":[],"related_works":["https://openalex.org/W2353644209","https://openalex.org/W2348743188","https://openalex.org/W4387423451","https://openalex.org/W2902317490","https://openalex.org/W2025460258","https://openalex.org/W2296384492","https://openalex.org/W1208794941","https://openalex.org/W4385073642","https://openalex.org/W2402524964","https://openalex.org/W2421034833"],"abstract_inverted_index":{"Supplementary":[0],"Figure":[1],"S1":[2],"from":[3],"BMS-536924":[4],"Reverses":[5],"IGF-IR-Induced":[6],"Transformation":[7],"of":[8,18],"Mammary":[9],"Epithelial":[10],"Cells":[11,20],"and":[12,16],"Causes":[13],"Growth":[14],"Inhibition":[15],"Polarization":[17],"MCF7":[19]},"counts_by_year":[],"updated_date":"2026-09-04T10:56:28.161419","created_date":"2025-10-10T00:00:00"}