{"id":"https://openalex.org/W4362425178","doi":"https://doi.org/10.1158/1055-9965.22437789.v1","title":"Supplementary Materials from Estimating TP53 Mutation Carrier Probability in Families with Li\u2013Fraumeni Syndrome Using LFSPRO","display_name":"Supplementary Materials from Estimating TP53 Mutation Carrier Probability in Families with Li\u2013Fraumeni Syndrome Using LFSPRO","publication_year":2023,"publication_date":"2023-03-31","ids":{"openalex":"https://openalex.org/W4362425178","doi":"https://doi.org/10.1158/1055-9965.22437789.v1"},"language":"en","primary_location":{"id":"doi:10.1158/1055-9965.22437789.v1","doi":"https://doi.org/10.1158/1055-9965.22437789.v1","is_oa":true,"landing_page_url":"http://dx.doi.org/10.1158/1055-9965.22437789.v1","pdf_url":null,"source":null,"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"acceptedVersion","is_accepted":true,"is_published":false,"raw_source_name":"American Association for Cancer Research","raw_type":"posted-content"},"volume":null,"type":"supplementary-materials","indexed_in":["crossref"],"open_access":{"is_oa":true,"oa_status":"gold","oa_url":"http://dx.doi.org/10.1158/1055-9965.22437789.v1","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5076954489","display_name":"Gang Peng","orcid":"https://orcid.org/0000-0003-0307-9351","observed_orcids":["https://orcid.org/0000-0003-0307-9351"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Gang Peng","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5034008196","display_name":"Jasmina Bojadzieva","orcid":"https://orcid.org/0000-0002-1657-6034","observed_orcids":["https://orcid.org/0000-0002-1657-6034"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Jasmina Bojadzieva","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5080428614","display_name":"Mandy L. Ballinger","orcid":"https://orcid.org/0000-0002-9706-0514","observed_orcids":["https://orcid.org/0000-0002-9706-0514"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Mandy L. Ballinger","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5108050360","display_name":"Jialu Li","orcid":"https://orcid.org/0000-0002-6411-6876","observed_orcids":["https://orcid.org/0000-0002-6411-6876"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Jialu Li","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5012591920","display_name":"Amanda L. Blackford","orcid":"https://orcid.org/0000-0002-6519-4833","observed_orcids":["https://orcid.org/0000-0002-6519-4833"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Amanda L. Blackford","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":null,"display_name":"Phuong L. Mai","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Phuong L. Mai","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5006363663","display_name":"Sharon A. Savage","orcid":"https://orcid.org/0000-0001-6006-0740","observed_orcids":["https://orcid.org/0000-0001-6006-0740"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Sharon A. Savage","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5057483557","display_name":"David Morgan Thomas","orcid":"https://orcid.org/0000-0002-2527-5428","observed_orcids":["https://orcid.org/0000-0002-2527-5428"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"David M. Thomas","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5060302560","display_name":"Louise C. Strong","orcid":"https://orcid.org/0000-0001-6795-3744","observed_orcids":["https://orcid.org/0000-0001-6795-3744"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Louise C. Strong","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"last","author":{"id":"https://openalex.org/A5100354894","display_name":"Wenyi Wang","orcid":"https://orcid.org/0000-0003-0617-9438","observed_orcids":["https://orcid.org/0000-0003-0617-9438"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Wenyi Wang","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]}],"institutions":[],"countries_distinct_count":0,"institutions_distinct_count":0,"corresponding_author_ids":[],"corresponding_institution_ids":[],"apc_list":null,"apc_paid":null,"fwci":null,"has_fulltext":false,"cited_by_count":0,"citation_normalized_percentile":null,"cited_by_percentile_year":null,"biblio":{"volume":null,"issue":null,"first_page":null,"last_page":null},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10583","display_name":"Cancer-related Molecular Pathways","score":0.41260001063346863,"subfield":{"id":"https://openalex.org/subfields/2730","display_name":"Oncology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T10583","display_name":"Cancer-related Molecular Pathways","score":0.41260001063346863,"subfield":{"id":"https://openalex.org/subfields/2730","display_name":"Oncology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10769","display_name":"BRCA gene mutations in cancer","score":0.19539999961853027,"subfield":{"id":"https://openalex.org/subfields/1311","display_name":"Genetics"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T11642","display_name":"Genomics and Rare Diseases","score":0.09679999947547913,"subfield":{"id":"https://openalex.org/subfields/1311","display_name":"Genetics"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/tp53-mutation","display_name":"TP53 mutation","score":0.8149999976158142},{"id":"https://openalex.org/keywords/li-fraumeni-syndrome","display_name":"Li-Fraumeni syndrome","score":0.9470000267028809},{"id":"https://openalex.org/keywords/germline-tp53-mutation","display_name":"germline TP53 mutation","score":0.7229999899864197},{"id":"https://openalex.org/keywords/cancer-risk-prediction","display_name":"cancer risk prediction","score":0.45899999141693115}],"concepts":[{"id":"https://openalex.org/C2777169287","wikidata":"https://www.wikidata.org/wiki/Q187542","display_name":"Li\u2013Fraumeni syndrome","level":5,"score":0.8693867921829224},{"id":"https://openalex.org/C501734568","wikidata":"https://www.wikidata.org/wiki/Q42918","display_name":"Mutation","level":3,"score":0.5652284026145935},{"id":"https://openalex.org/C54355233","wikidata":"https://www.wikidata.org/wiki/Q7162","display_name":"Genetics","level":1,"score":0.45962822437286377},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.35201579332351685},{"id":"https://openalex.org/C502942594","wikidata":"https://www.wikidata.org/wiki/Q3421914","display_name":"Cancer research","level":1,"score":0.3440471291542053},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.32301753759384155},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.2842745780944824},{"id":"https://openalex.org/C13514818","wikidata":"https://www.wikidata.org/wiki/Q5552256","display_name":"Germline mutation","level":4,"score":0.1565856635570526},{"id":"https://openalex.org/C104317684","wikidata":"https://www.wikidata.org/wiki/Q7187","display_name":"Gene","level":2,"score":0.07824558019638062}],"mesh":[],"locations_count":2,"locations":[{"id":"doi:10.1158/1055-9965.22437789.v1","doi":"https://doi.org/10.1158/1055-9965.22437789.v1","is_oa":true,"landing_page_url":"http://dx.doi.org/10.1158/1055-9965.22437789.v1","pdf_url":null,"source":null,"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"acceptedVersion","is_accepted":true,"is_published":false,"raw_source_name":"American Association for Cancer Research","raw_type":"posted-content"},{"id":"pmh:oai:figshare.com:article/22437789","doi":null,"is_oa":true,"landing_page_url":"https://figshare.com/articles/journal_contribution/Supplementary_Materials_from_Estimating_i_TP53_i_Mutation_Carrier_Probability_in_Families_with_Li_Fraumeni_Syndrome_Using_LFSPRO/22437789","pdf_url":null,"source":{"id":"https://openalex.org/S4377196282","display_name":"Figshare","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I4210132348","host_organization_name":"Figshare (United Kingdom)","host_organization_lineage":["https://openalex.org/I4210132348"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"","raw_type":"Text"}],"best_oa_location":{"id":"doi:10.1158/1055-9965.22437789.v1","doi":"https://doi.org/10.1158/1055-9965.22437789.v1","is_oa":true,"landing_page_url":"http://dx.doi.org/10.1158/1055-9965.22437789.v1","pdf_url":null,"source":null,"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"acceptedVersion","is_accepted":true,"is_published":false,"raw_source_name":"American Association for Cancer Research","raw_type":"posted-content"},"sustainable_development_goals":[{"id":"https://metadata.un.org/sdg/3","score":0.9537000060081482,"display_name":"Good health and well-being"}],"sustainable_development_goals_aurora":[{"id":"https://metadata.un.org/sdg/3","score":0.699999988079071,"display_name":"Good health and well-being"}],"study_designs":[],"awards":[],"funders":[],"has_content":{"pdf":false,"grobid_xml":false},"content_urls":null,"referenced_works_count":0,"referenced_works":[],"related_works":["https://openalex.org/W2581693404","https://openalex.org/W4361942507","https://openalex.org/W3171519528","https://openalex.org/W2565476966","https://openalex.org/W7056791044","https://openalex.org/W4322771973","https://openalex.org/W4286294354","https://openalex.org/W1596222665","https://openalex.org/W4382293525","https://openalex.org/W4361826747"],"abstract_inverted_index":{"Medical":[0],"records":[1],"and":[2,16],"death":[3],"certificates":[4],"were":[5],"used":[6],"to":[7],"confirm":[8],"cancers":[9],"where":[10],"possible,":[11],"with":[12],"success":[13],"in":[14,26],"77%":[15],"6%,":[17],"respectively,":[18],"for":[19],"an":[20],"overall":[21],"confirmation":[22],"rate":[23],"of":[24],"83%":[25],"the":[27],"MDACC":[28],"cohort.":[29]},"counts_by_year":[],"updated_date":"2026-10-16T09:59:22.235173","created_date":"2023-04-05T00:00:00"}