{"id":"https://openalex.org/W4362397360","doi":"https://doi.org/10.1158/1078-0432.22456929","title":"Supplemental Material from Toward Personalized Lymphoma Immunotherapy: Identification of Common Driver Mutations Recognized by Patient CD8+ T Cells","display_name":"Supplemental Material from Toward Personalized Lymphoma Immunotherapy: Identification of Common Driver Mutations Recognized by Patient CD8+ T Cells","publication_year":2023,"publication_date":"2023-03-31","ids":{"openalex":"https://openalex.org/W4362397360","doi":"https://doi.org/10.1158/1078-0432.22456929"},"language":"en","primary_location":{"id":"doi:10.1158/1078-0432.22456929","doi":"https://doi.org/10.1158/1078-0432.22456929","is_oa":true,"landing_page_url":"https://doi.org/10.1158/1078-0432.22456929","pdf_url":null,"source":null,"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"acceptedVersion","is_accepted":true,"is_published":false,"raw_source_name":"American Association for Cancer Research","raw_type":"posted-content"},"volume":null,"type":"supplementary-materials","indexed_in":["crossref"],"open_access":{"is_oa":true,"oa_status":"gold","oa_url":"https://doi.org/10.1158/1078-0432.22456929","any_repository_has_fulltext":null},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5104110172","display_name":"Julie S. Nielsen","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Julie S. Nielsen","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5028354985","display_name":"Colin G. Sedgwick","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Colin G. Sedgwick","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5057060792","display_name":"Aniqa Shahid","orcid":"https://orcid.org/0000-0002-8362-1528","observed_orcids":["https://orcid.org/0000-0002-8362-1528"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Aniqa Shahid","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5102223074","display_name":"Zusheng Zong","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Zusheng Zong","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5054186329","display_name":"Zabrina L. Brumme","orcid":"https://orcid.org/0000-0002-8157-1037","observed_orcids":["https://orcid.org/0000-0002-8157-1037"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Zabrina L. Brumme","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5025681426","display_name":"Stephen W. Yu","orcid":"https://orcid.org/0000-0002-0107-5771","observed_orcids":["https://orcid.org/0000-0002-0107-5771"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Stephen Yu","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5058928149","display_name":"Lewis Y. Liu","orcid":"https://orcid.org/0000-0001-9740-8261","observed_orcids":["https://orcid.org/0000-0001-9740-8261","https://orcid.org/0000-0002-4957-0771"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Lewis Liu","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5053318832","display_name":"David R. Kroeger","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"David R. Kroeger","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5081299017","display_name":"Steven Peter Treon","orcid":"https://orcid.org/0000-0001-6393-6154","observed_orcids":["https://orcid.org/0000-0001-6393-6154"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Steven P. Treon","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5022658681","display_name":"Joseph Michael Connors","orcid":"https://orcid.org/0000-0002-1361-7531","observed_orcids":["https://orcid.org/0000-0002-1361-7531"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Joseph M. Connors","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5031758990","display_name":"Randy D. Gascoyne","orcid":"https://orcid.org/0000-0002-2610-5690","observed_orcids":["https://orcid.org/0000-0002-2610-5690"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Randy D. Gascoyne","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5110202715","display_name":"Brian R. Berry","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Brian R. Berry","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5070061359","display_name":"Marco A. Marra","orcid":"https://orcid.org/0000-0001-7146-7175","observed_orcids":["https://orcid.org/0000-0001-7146-7175"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Marco A. Marra","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5081644676","display_name":"Ryan D. Morin","orcid":"https://orcid.org/0000-0003-2932-7800","observed_orcids":["https://orcid.org/0000-0003-2932-7800"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Ryan D. Morin","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5079993805","display_name":"Nicol A. Macpherson","orcid":"https://orcid.org/0009-0005-5574-2188","observed_orcids":["https://orcid.org/0009-0005-5574-2188"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Nicol Macpherson","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"last","author":{"id":"https://openalex.org/A5058837420","display_name":"Brad H. Nelson","orcid":"https://orcid.org/0000-0002-4445-5539","observed_orcids":["https://orcid.org/0000-0002-4445-5539"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Brad H. Nelson","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]}],"institutions":[],"countries_distinct_count":0,"institutions_distinct_count":0,"corresponding_author_ids":[],"corresponding_institution_ids":[],"apc_list":null,"apc_paid":null,"fwci":null,"has_fulltext":false,"cited_by_count":0,"citation_normalized_percentile":null,"cited_by_percentile_year":null,"biblio":{"volume":null,"issue":null,"first_page":null,"last_page":null},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10185","display_name":"Lymphoma Diagnosis and Treatment","score":0.6859999895095825,"subfield":{"id":"https://openalex.org/subfields/2734","display_name":"Pathology and Forensic Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T10185","display_name":"Lymphoma Diagnosis and Treatment","score":0.6859999895095825,"subfield":{"id":"https://openalex.org/subfields/2734","display_name":"Pathology and Forensic Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10158","display_name":"Cancer Immunotherapy and Biomarkers","score":0.12430000305175781,"subfield":{"id":"https://openalex.org/subfields/2730","display_name":"Oncology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T11491","display_name":"CAR-T cell therapy research","score":0.06199999898672104,"subfield":{"id":"https://openalex.org/subfields/2730","display_name":"Oncology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/follicular-lymphoma","display_name":"follicular lymphoma","score":0.9950000047683716},{"id":"https://openalex.org/keywords/personalized-immunotherapy","display_name":"personalized immunotherapy","score":0.8040000200271606},{"id":"https://openalex.org/keywords/driver-mutations","display_name":"driver mutations","score":0.8920000195503235},{"id":"https://openalex.org/keywords/cd8-t-cells","display_name":"CD8+ T cells","score":0.9020000100135803},{"id":"https://openalex.org/keywords/t-cell-recognition","display_name":"T cell recognition","score":0.44600000977516174},{"id":"https://openalex.org/keywords/hla-class-i-binding","display_name":"HLA class I binding","score":0.6399999856948853},{"id":"https://openalex.org/keywords/mutant-peptides","display_name":"mutant peptides","score":0.8230000138282776},{"id":"https://openalex.org/keywords/somatic-mutations","display_name":"somatic mutations","score":0.8140000104904175},{"id":"https://openalex.org/keywords/tcr-repertoire","display_name":"T cell receptor repertoire","score":0.3190000057220459}],"concepts":[{"id":"https://openalex.org/C2780868878","wikidata":"https://www.wikidata.org/wiki/Q1660197","display_name":"Immunogenicity","level":3,"score":0.7579828500747681},{"id":"https://openalex.org/C2777058707","wikidata":"https://www.wikidata.org/wiki/Q123251","display_name":"Follicular lymphoma","level":3,"score":0.7209253907203674},{"id":"https://openalex.org/C167672396","wikidata":"https://www.wikidata.org/wiki/Q417800","display_name":"CD8","level":3,"score":0.6138613224029541},{"id":"https://openalex.org/C2779338263","wikidata":"https://www.wikidata.org/wiki/Q208414","display_name":"Lymphoma","level":2,"score":0.4692891538143158},{"id":"https://openalex.org/C203014093","wikidata":"https://www.wikidata.org/wiki/Q101929","display_name":"Immunology","level":1,"score":0.46766555309295654},{"id":"https://openalex.org/C72563966","wikidata":"https://www.wikidata.org/wiki/Q1303415","display_name":"Cohort","level":2,"score":0.45634448528289795},{"id":"https://openalex.org/C2777701055","wikidata":"https://www.wikidata.org/wiki/Q1427096","display_name":"Immunotherapy","level":3,"score":0.4266365170478821},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.4137359857559204},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.38692519068717957},{"id":"https://openalex.org/C153911025","wikidata":"https://www.wikidata.org/wiki/Q7202","display_name":"Molecular biology","level":1,"score":0.35761553049087524},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.2665949761867523},{"id":"https://openalex.org/C159654299","wikidata":"https://www.wikidata.org/wiki/Q79460","display_name":"Antibody","level":2,"score":0.2588346600532532},{"id":"https://openalex.org/C147483822","wikidata":"https://www.wikidata.org/wiki/Q103537","display_name":"Antigen","level":2,"score":0.25796765089035034},{"id":"https://openalex.org/C8891405","wikidata":"https://www.wikidata.org/wiki/Q1059","display_name":"Immune system","level":2,"score":0.2383335530757904}],"mesh":[],"locations_count":1,"locations":[{"id":"doi:10.1158/1078-0432.22456929","doi":"https://doi.org/10.1158/1078-0432.22456929","is_oa":true,"landing_page_url":"https://doi.org/10.1158/1078-0432.22456929","pdf_url":null,"source":null,"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"acceptedVersion","is_accepted":true,"is_published":false,"raw_source_name":"American Association for Cancer Research","raw_type":"posted-content"}],"best_oa_location":{"id":"doi:10.1158/1078-0432.22456929","doi":"https://doi.org/10.1158/1078-0432.22456929","is_oa":true,"landing_page_url":"https://doi.org/10.1158/1078-0432.22456929","pdf_url":null,"source":null,"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"acceptedVersion","is_accepted":true,"is_published":false,"raw_source_name":"American Association for Cancer Research","raw_type":"posted-content"},"sustainable_development_goals":[{"score":0.9391000270843506,"display_name":"Good health and well-being","id":"https://metadata.un.org/sdg/3"}],"study_designs":[],"awards":[],"funders":[],"has_content":{"pdf":false,"grobid_xml":false},"content_urls":null,"referenced_works_count":9,"referenced_works":["https://openalex.org/W336368690","https://openalex.org/W339313837","https://openalex.org/W2001663034","https://openalex.org/W2024373518","https://openalex.org/W2058899594","https://openalex.org/W2100311911","https://openalex.org/W2160827709","https://openalex.org/W2161724277","https://openalex.org/W7055337858"],"related_works":["https://openalex.org/W2184558141","https://openalex.org/W4361945666","https://openalex.org/W2552270641","https://openalex.org/W2890354113","https://openalex.org/W3157637801","https://openalex.org/W2561391321","https://openalex.org/W2579564430","https://openalex.org/W4362525484","https://openalex.org/W4282919522","https://openalex.org/W4388033625"],"abstract_inverted_index":{"Supplemental":[0],"Methods.":[1],"Table":[2,23,31,48],"S1.":[3,61],"Frequency":[4],"of":[5,27,64,96],"hematopoietic":[6],"subsets":[7],"in":[8,19,41,44,56,75,88],"PBMC":[9],"at":[10],"all":[11],"time":[12],"points":[13],"for":[14,18,55,83,87],"patient":[15],"samples":[16],"used":[17],"vitro":[20,57,89],"immunogenicity":[21,58,90],"experiments":[22],"S2:":[24],"Clinical":[25,81],"characteristics":[26],"follicular":[28,45],"lymphoma":[29,46],"cohorts":[30],"S3.":[32,93],"Amino":[33],"acid":[34],"changes":[35],"encoded":[36],"by":[37],"somatic":[38],"mutations":[39],"identified":[40],"candidate":[42],"genes":[43],"cohort":[47,59,85],"S4.":[49],"Patient":[50],"HLA":[51,71],"class":[52,72],"I":[53,73],"alleles":[54],"Figure":[60,79,92],"The":[62],"number":[63],"mutant":[65,97],"peptides":[66],"predicted":[67],"to":[68],"bind":[69],"patient-specific":[70],"molecules":[74],"the":[76],"sequencing":[77],"cohort.":[78],"S2.":[80],"timeline":[82],"13-patient":[84],"selected":[86],"studies.":[91],"CD8":[94],"status":[95],"peptide-reactive":[98],"T":[99],"cells.":[100]},"counts_by_year":[],"updated_date":"2026-10-17T09:40:24.721904","created_date":"2023-04-05T00:00:00"}