{"id":"https://openalex.org/W4362395081","doi":"https://doi.org/10.1158/1078-0432.22449768","title":"Supplementary Movie S2 from A Genetically Engineered Oncolytic Adenovirus Decoys and Lethally Traps Quiescent Cancer Stem\u2013like Cells in S/G2/M Phases","display_name":"Supplementary Movie S2 from A Genetically Engineered Oncolytic Adenovirus Decoys and Lethally Traps Quiescent Cancer Stem\u2013like Cells in S/G2/M Phases","publication_year":2023,"publication_date":"2023-03-31","ids":{"openalex":"https://openalex.org/W4362395081","doi":"https://doi.org/10.1158/1078-0432.22449768"},"language":"en","primary_location":{"id":"doi:10.1158/1078-0432.22449768","doi":"https://doi.org/10.1158/1078-0432.22449768","is_oa":true,"landing_page_url":"https://doi.org/10.1158/1078-0432.22449768","pdf_url":null,"source":null,"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"acceptedVersion","is_accepted":true,"is_published":false,"raw_source_name":"American Association for Cancer Research","raw_type":"posted-content"},"volume":null,"type":"supplementary-materials","indexed_in":["crossref"],"open_access":{"is_oa":true,"oa_status":"gold","oa_url":"https://doi.org/10.1158/1078-0432.22449768","any_repository_has_fulltext":null},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5062335013","display_name":"Shuya Yano","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Shuya Yano","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5015421086","display_name":"Hiroshi Tazawa","orcid":"https://orcid.org/0000-0003-4658-1050","observed_orcids":["https://orcid.org/0000-0003-4658-1050"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Hiroshi Tazawa","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5101481270","display_name":"Yuuri Hashimoto","orcid":"https://orcid.org/0000-0002-5934-6060","observed_orcids":["https://orcid.org/0000-0002-5934-6060"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Yuuri Hashimoto","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5055129091","display_name":"Yasuhiro Shirakawa","orcid":"https://orcid.org/0000-0003-4698-5119","observed_orcids":["https://orcid.org/0000-0003-4698-5119"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Yasuhiro Shirakawa","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5020188029","display_name":"Shinji Kuroda","orcid":"https://orcid.org/0000-0002-4484-1253","observed_orcids":["https://orcid.org/0000-0002-4484-1253"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Shinji Kuroda","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5111619755","display_name":"Masahiko Nishizaki","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Masahiko Nishizaki","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5035456514","display_name":"Hiroyuki Kishimoto","orcid":"https://orcid.org/0000-0001-8174-3508","observed_orcids":["https://orcid.org/0000-0001-8174-3508"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Hiroyuki Kishimoto","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5014758676","display_name":"Futoshi Uno","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Futoshi Uno","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5055180271","display_name":"Takeshi Nagasaka","orcid":"https://orcid.org/0000-0002-4236-350X","observed_orcids":["https://orcid.org/0000-0002-4236-350X"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Takeshi Nagasaka","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5114045812","display_name":"Yasuo Urata","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Yasuo Urata","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5049100460","display_name":"Shunsuke Kagawa","orcid":"https://orcid.org/0000-0002-3610-8211","observed_orcids":["https://orcid.org/0000-0002-3610-8211"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Shunsuke Kagawa","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5040819666","display_name":"Robert M. Hoffman","orcid":"https://orcid.org/0000-0002-0049-0041","observed_orcids":["https://orcid.org/0000-0002-0049-0041"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Robert M. Hoffman","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"last","author":{"id":"https://openalex.org/A5068717107","display_name":"Toshiyoshi Fujiwara","orcid":"https://orcid.org/0000-0002-5377-6051","observed_orcids":["https://orcid.org/0000-0002-5377-6051"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Toshiyoshi Fujiwara","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]}],"institutions":[],"countries_distinct_count":0,"institutions_distinct_count":0,"corresponding_author_ids":[],"corresponding_institution_ids":[],"apc_list":null,"apc_paid":null,"fwci":null,"has_fulltext":false,"cited_by_count":0,"citation_normalized_percentile":null,"cited_by_percentile_year":null,"biblio":{"volume":null,"issue":null,"first_page":null,"last_page":null},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10613","display_name":"Virus-based gene therapy research","score":0.9750999808311462,"subfield":{"id":"https://openalex.org/subfields/1311","display_name":"Genetics"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T10613","display_name":"Virus-based gene therapy research","score":0.9750999808311462,"subfield":{"id":"https://openalex.org/subfields/1311","display_name":"Genetics"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10336","display_name":"Cancer Cells and Metastasis","score":0.008100000210106373,"subfield":{"id":"https://openalex.org/subfields/2730","display_name":"Oncology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10937","display_name":"Telomeres, Telomerase, and Senescence","score":0.002899999963119626,"subfield":{"id":"https://openalex.org/subfields/2737","display_name":"Physiology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/oncolytic-adenovirus","display_name":"oncolytic adenovirus","score":0.9810000061988831},{"id":"https://openalex.org/keywords/cancer-stem-like-cells","display_name":"cancer stem-like cells","score":0.7580000162124634},{"id":"https://openalex.org/keywords/fucci","display_name":"FUCCI","score":0.6729999780654907},{"id":"https://openalex.org/keywords/cell-cycle-phases","display_name":"cell cycle phases","score":0.6069999933242798},{"id":"https://openalex.org/keywords/cellular-quiescence","display_name":"quiescent cells","score":0.6859999895095825},{"id":"https://openalex.org/keywords/tumor-spheres","display_name":"tumor spheres","score":0.8180000185966492},{"id":"https://openalex.org/keywords/3d-cell-culture","display_name":"3D cell culture","score":0.8429999947547913},{"id":"https://openalex.org/keywords/time-lapse-imaging","display_name":"time-lapse imaging","score":0.7820000052452087}],"concepts":[{"id":"https://openalex.org/C82210918","wikidata":"https://www.wikidata.org/wiki/Q1560099","display_name":"Oncolytic virus","level":3,"score":0.5855261087417603},{"id":"https://openalex.org/C7070889","wikidata":"https://www.wikidata.org/wiki/Q902488","display_name":"Monolayer","level":2,"score":0.5612317323684692},{"id":"https://openalex.org/C3019111730","wikidata":"https://www.wikidata.org/wiki/Q159236","display_name":"Genetically engineered","level":3,"score":0.48366984724998474},{"id":"https://openalex.org/C121608353","wikidata":"https://www.wikidata.org/wiki/Q12078","display_name":"Cancer","level":2,"score":0.4772917330265045},{"id":"https://openalex.org/C153911025","wikidata":"https://www.wikidata.org/wiki/Q7202","display_name":"Molecular biology","level":1,"score":0.43771201372146606},{"id":"https://openalex.org/C159047783","wikidata":"https://www.wikidata.org/wiki/Q7215","display_name":"Virology","level":1,"score":0.42620381712913513},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.40634265542030334},{"id":"https://openalex.org/C502942594","wikidata":"https://www.wikidata.org/wiki/Q3421914","display_name":"Cancer research","level":1,"score":0.393575519323349},{"id":"https://openalex.org/C121332964","wikidata":"https://www.wikidata.org/wiki/Q413","display_name":"Physics","level":0,"score":0.3683145046234131},{"id":"https://openalex.org/C54355233","wikidata":"https://www.wikidata.org/wiki/Q7162","display_name":"Genetics","level":1,"score":0.19118636846542358},{"id":"https://openalex.org/C104317684","wikidata":"https://www.wikidata.org/wiki/Q7187","display_name":"Gene","level":2,"score":0.14359676837921143},{"id":"https://openalex.org/C55493867","wikidata":"https://www.wikidata.org/wiki/Q7094","display_name":"Biochemistry","level":1,"score":0.0921822190284729}],"mesh":[],"locations_count":1,"locations":[{"id":"doi:10.1158/1078-0432.22449768","doi":"https://doi.org/10.1158/1078-0432.22449768","is_oa":true,"landing_page_url":"https://doi.org/10.1158/1078-0432.22449768","pdf_url":null,"source":null,"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"acceptedVersion","is_accepted":true,"is_published":false,"raw_source_name":"American Association for Cancer Research","raw_type":"posted-content"}],"best_oa_location":{"id":"doi:10.1158/1078-0432.22449768","doi":"https://doi.org/10.1158/1078-0432.22449768","is_oa":true,"landing_page_url":"https://doi.org/10.1158/1078-0432.22449768","pdf_url":null,"source":null,"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"acceptedVersion","is_accepted":true,"is_published":false,"raw_source_name":"American Association for Cancer Research","raw_type":"posted-content"},"sustainable_development_goals":[{"id":"https://metadata.un.org/sdg/3","score":0.428600013256073,"display_name":"Good health and well-being"}],"study_designs":[],"awards":[],"funders":[],"has_content":{"grobid_xml":false,"pdf":false},"content_urls":null,"referenced_works_count":0,"referenced_works":[],"related_works":["https://openalex.org/W2524896967","https://openalex.org/W4361944993","https://openalex.org/W2289120722","https://openalex.org/W1571918456","https://openalex.org/W1599007654","https://openalex.org/W2032926438","https://openalex.org/W2790576209","https://openalex.org/W3137389997","https://openalex.org/W4286853613","https://openalex.org/W2004295263"],"abstract_inverted_index":{"Supplementary":[0],"Movie":[1],"S2":[2],"-":[3],"MOV":[4],"file":[5],"4338K,":[6],"Time-lapse":[7],"imaging":[8,46],"of":[9],"FUCCI-expressing":[10],"tumor":[11,22],"spheres":[12],"cultured":[13],"in":[14,24,53],"three-dimensional":[15],"culture":[16,26],"without":[17],"serum":[18,28],"(3D":[19],"culture),":[20],"or":[21,57,63],"sphere":[23],"monolayer":[25],"with":[27],"(monolayer":[29],"culture).":[30],"Images":[31],"were":[32],"acquired":[33],"every":[34],"20":[35],"min.":[36],"The":[37,51],"playback":[38],"speed":[39],"is":[40],"12,342":[41],"x":[42],"real":[43],"time.":[44],"Total":[45],"time":[47],"=":[48],"48":[49],"hours.":[50],"cells":[52],"G0/":[54],"G1,":[55],"S,":[56],"G2/M":[58],"phases":[59],"appear":[60],"red,":[61],"yellow,":[62],"green,":[64],"respectively.":[65]},"counts_by_year":[],"updated_date":"2026-10-14T16:39:01.820549","created_date":"2023-04-05T00:00:00"}