{"id":"https://openalex.org/W4362167709","doi":"https://doi.org/10.1158/1078-0432.22470333","title":"Supplementary Data from Engineering the TGF\u03b2 Receptor to Enhance the Therapeutic Potential of Natural Killer Cells as an Immunotherapy for Neuroblastoma","display_name":"Supplementary Data from Engineering the TGF\u03b2 Receptor to Enhance the Therapeutic Potential of Natural Killer Cells as an Immunotherapy for Neuroblastoma","publication_year":2023,"publication_date":"2023-03-31","ids":{"openalex":"https://openalex.org/W4362167709","doi":"https://doi.org/10.1158/1078-0432.22470333"},"language":"en","primary_location":{"id":"doi:10.1158/1078-0432.22470333","doi":"https://doi.org/10.1158/1078-0432.22470333","is_oa":true,"landing_page_url":"https://doi.org/10.1158/1078-0432.22470333","pdf_url":null,"source":null,"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"acceptedVersion","is_accepted":true,"is_published":false,"raw_source_name":"American Association for Cancer Research","raw_type":"posted-content"},"volume":null,"type":"supplementary-materials","indexed_in":["crossref"],"open_access":{"is_oa":true,"oa_status":"gold","oa_url":"https://doi.org/10.1158/1078-0432.22470333","any_repository_has_fulltext":null},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5003003191","display_name":"Rachel A. Burga","orcid":"https://orcid.org/0000-0002-0204-8986","observed_orcids":["https://orcid.org/0000-0002-0204-8986"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Rachel A. Burga","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5082887496","display_name":"Eric S. Yvon","orcid":"https://orcid.org/0000-0003-3822-6710","observed_orcids":["https://orcid.org/0000-0003-3822-6710"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Eric Yvon","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5083117389","display_name":"Elizabeth A. Chorvinsky","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Elizabeth Chorvinsky","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5041746704","display_name":"Rohan Fernandes","orcid":"https://orcid.org/0000-0001-9439-4626","observed_orcids":["https://orcid.org/0000-0001-9439-4626"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Rohan Fernandes","raw_affiliation_strings":[],"raw_orcid":"https://orcid.org/0000-0001-9439-4626","affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5033997937","display_name":"Carolina Colli Cruz","orcid":"https://orcid.org/0000-0001-7065-3769","observed_orcids":["https://orcid.org/0000-0001-7065-3769"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"C. Russell Y. Cruz","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"last","author":{"id":"https://openalex.org/A5006134549","display_name":"Catherine M. Bollard","orcid":"https://orcid.org/0000-0001-5140-9090","observed_orcids":["https://orcid.org/0000-0001-5140-9090"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Catherine M. Bollard","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]}],"institutions":[],"countries_distinct_count":0,"institutions_distinct_count":0,"corresponding_author_ids":[],"corresponding_institution_ids":[],"apc_list":null,"apc_paid":null,"fwci":null,"has_fulltext":false,"cited_by_count":0,"citation_normalized_percentile":null,"cited_by_percentile_year":null,"biblio":{"volume":null,"issue":null,"first_page":null,"last_page":null},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T11020","display_name":"Immune Cell Function and Interaction","score":0.9628999829292297,"subfield":{"id":"https://openalex.org/subfields/2403","display_name":"Immunology"},"field":{"id":"https://openalex.org/fields/24","display_name":"Immunology and Microbiology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T11020","display_name":"Immune Cell Function and Interaction","score":0.9628999829292297,"subfield":{"id":"https://openalex.org/subfields/2403","display_name":"Immunology"},"field":{"id":"https://openalex.org/fields/24","display_name":"Immunology and Microbiology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T12226","display_name":"Neuroblastoma Research and Treatments","score":0.023099999874830246,"subfield":{"id":"https://openalex.org/subfields/2728","display_name":"Neurology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T11491","display_name":"CAR-T cell therapy research","score":0.004100000020116568,"subfield":{"id":"https://openalex.org/subfields/2730","display_name":"Oncology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/neuroblastoma","display_name":"neuroblastoma","score":0.8640000224113464},{"id":"https://openalex.org/keywords/natural-killer-cells","display_name":"natural killer cells","score":0.9739999771118164},{"id":"https://openalex.org/keywords/nk-cell-persistence","display_name":"NK cell persistence","score":0.8370000123977661},{"id":"https://openalex.org/keywords/nk-cell-therapy","display_name":"NK cell therapy","score":0.7749999761581421},{"id":"https://openalex.org/keywords/nk-cell-phenotype","display_name":"NK cell phenotype","score":0.7770000100135803},{"id":"https://openalex.org/keywords/nk-cell-proliferation","display_name":"NK cell proliferation","score":0.7820000052452087},{"id":"https://openalex.org/keywords/tumor-progression","display_name":"tumor progression","score":0.8220000267028809},{"id":"https://openalex.org/keywords/progression-free-survival","display_name":"progression-free survival","score":0.8169999718666077},{"id":"https://openalex.org/keywords/tumor-bearing-mice","display_name":"tumor-bearing mice","score":0.5410000085830688}],"concepts":[{"id":"https://openalex.org/C2776715637","wikidata":"https://www.wikidata.org/wiki/Q938205","display_name":"Neuroblastoma","level":3,"score":0.8197458386421204},{"id":"https://openalex.org/C2777701055","wikidata":"https://www.wikidata.org/wiki/Q1427096","display_name":"Immunotherapy","level":3,"score":0.5667153000831604},{"id":"https://openalex.org/C502942594","wikidata":"https://www.wikidata.org/wiki/Q3421914","display_name":"Cancer research","level":1,"score":0.5652898550033569},{"id":"https://openalex.org/C2778630268","wikidata":"https://www.wikidata.org/wiki/Q17113277","display_name":"Cell sorting","level":3,"score":0.5126923322677612},{"id":"https://openalex.org/C1491633281","wikidata":"https://www.wikidata.org/wiki/Q7868","display_name":"Cell","level":2,"score":0.4692549407482147},{"id":"https://openalex.org/C2778102761","wikidata":"https://www.wikidata.org/wiki/Q332181","display_name":"Natural killer cell","level":4,"score":0.4669210910797119},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.4476180374622345},{"id":"https://openalex.org/C203014093","wikidata":"https://www.wikidata.org/wiki/Q101929","display_name":"Immunology","level":1,"score":0.3457772135734558},{"id":"https://openalex.org/C81885089","wikidata":"https://www.wikidata.org/wiki/Q189082","display_name":"Cell culture","level":2,"score":0.18995362520217896},{"id":"https://openalex.org/C8891405","wikidata":"https://www.wikidata.org/wiki/Q1059","display_name":"Immune system","level":2,"score":0.17557257413864136},{"id":"https://openalex.org/C154317977","wikidata":"https://www.wikidata.org/wiki/Q376266","display_name":"Cytotoxic T cell","level":3,"score":0.17335116863250732},{"id":"https://openalex.org/C202751555","wikidata":"https://www.wikidata.org/wiki/Q221681","display_name":"In vitro","level":2,"score":0.054528623819351196},{"id":"https://openalex.org/C54355233","wikidata":"https://www.wikidata.org/wiki/Q7162","display_name":"Genetics","level":1,"score":0.050300806760787964}],"mesh":[],"locations_count":1,"locations":[{"id":"doi:10.1158/1078-0432.22470333","doi":"https://doi.org/10.1158/1078-0432.22470333","is_oa":true,"landing_page_url":"https://doi.org/10.1158/1078-0432.22470333","pdf_url":null,"source":null,"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"acceptedVersion","is_accepted":true,"is_published":false,"raw_source_name":"American Association for Cancer Research","raw_type":"posted-content"}],"best_oa_location":{"id":"doi:10.1158/1078-0432.22470333","doi":"https://doi.org/10.1158/1078-0432.22470333","is_oa":true,"landing_page_url":"https://doi.org/10.1158/1078-0432.22470333","pdf_url":null,"source":null,"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"acceptedVersion","is_accepted":true,"is_published":false,"raw_source_name":"American Association for Cancer Research","raw_type":"posted-content"},"sustainable_development_goals":[{"display_name":"Good health and well-being","score":0.9476000070571899,"id":"https://metadata.un.org/sdg/3"}],"study_designs":[],"awards":[],"funders":[],"has_content":{"pdf":false,"grobid_xml":false},"content_urls":null,"referenced_works_count":0,"referenced_works":[],"related_works":["https://openalex.org/W4313383613","https://openalex.org/W4361960225","https://openalex.org/W2801220820","https://openalex.org/W4393095522","https://openalex.org/W2611062837","https://openalex.org/W7110473585","https://openalex.org/W4399325226","https://openalex.org/W1998449624","https://openalex.org/W2572765595","https://openalex.org/W6902396363"],"abstract_inverted_index":{"Supplementary":[0,64],"Table":[1],"1:":[2],"NK":[3,13,23,28,35,53,58],"cell":[4,14,36,54,59],"persistence.":[5,55],"Fig.":[6,11,19,26,33,41,56],"S1.":[7],"Characterizing":[8],"SHSY5Y":[9],"neuroblastoma.":[10,18],"S2.":[12],"functionality":[15],"against":[16],"HTLA230":[17],"S3.":[20],"Verification":[21],"of":[22],"Cell":[24,29],"Sorting.":[25],"S4.":[27],"Phenotype":[30],"and":[31,46,52,66],"Proliferation.":[32],"S5.":[34],"phenotype":[37],"following":[38],"TGFbeta":[39],"exposure.":[40],"S6.":[42],"Neuroblastoma":[43],"tumor":[44],"progression":[45],"the":[47],"correlation":[48],"between":[49],"progression-free":[50],"survival":[51],"S7.":[57],"detection":[60],"in":[61],"neuroblastoma-bearing":[62],"mice.":[63],"Materials":[65],"Methods.":[67]},"counts_by_year":[],"updated_date":"2026-09-22T06:50:58.402377","created_date":"2023-04-05T00:00:00"}