{"id":"https://openalex.org/W4362015688","doi":"https://doi.org/10.1158/0008-5472.22393620","title":"Supplementary Table 7 from Dual Targeting of the Akt/mTOR Signaling Pathway Inhibits Castration-Resistant Prostate Cancer in a Genetically Engineered Mouse Model","display_name":"Supplementary Table 7 from Dual Targeting of the Akt/mTOR Signaling Pathway Inhibits Castration-Resistant Prostate Cancer in a Genetically Engineered Mouse Model","publication_year":2023,"publication_date":"2023-03-30","ids":{"openalex":"https://openalex.org/W4362015688","doi":"https://doi.org/10.1158/0008-5472.22393620"},"language":"en","primary_location":{"id":"doi:10.1158/0008-5472.22393620","doi":"https://doi.org/10.1158/0008-5472.22393620","is_oa":true,"landing_page_url":"http://dx.doi.org/10.1158/0008-5472.22393620","pdf_url":null,"source":null,"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"acceptedVersion","is_accepted":true,"is_published":false,"raw_source_name":"American Association for Cancer Research","raw_type":"posted-content"},"volume":null,"type":"supplementary-materials","indexed_in":["crossref"],"open_access":{"is_oa":true,"oa_status":"gold","oa_url":"http://dx.doi.org/10.1158/0008-5472.22393620","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5018934270","display_name":"Nicolas Floc\u2019h","orcid":"https://orcid.org/0009-0006-8557-2199","observed_orcids":["https://orcid.org/0009-0006-8557-2199"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Nicolas Floc'h","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5083070723","display_name":"Carolyn Waugh Kinkade","orcid":"https://orcid.org/0000-0002-8549-5553","observed_orcids":["https://orcid.org/0000-0002-8549-5553"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Carolyn Waugh Kinkade","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5074810793","display_name":"Takashi Kobayashi","orcid":"https://orcid.org/0000-0002-7240-4851","observed_orcids":["https://orcid.org/0000-0002-7240-4851","https://orcid.org/0000-0001-6098-6172"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Takashi Kobayashi","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5010218037","display_name":"\u00c0lvaro Ayt\u00e9s","orcid":"https://orcid.org/0000-0003-0725-5340","observed_orcids":["https://orcid.org/0000-0003-0725-5340"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Alvaro Aytes","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5104109891","display_name":"C\u00e9line Lef\u00e8bvre","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Celine Lefebvre","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5044821126","display_name":"Antonina Mitrofanova","orcid":"https://orcid.org/0000-0003-0671-6512","observed_orcids":["https://orcid.org/0000-0003-0671-6512"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Antonina Mitrofanova","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5057272279","display_name":"Robert D. Cardiff","orcid":"https://orcid.org/0000-0003-3088-8816","observed_orcids":["https://orcid.org/0000-0003-3088-8816"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Robert D. Cardiff","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5046245448","display_name":"Andrea Califano","orcid":"https://orcid.org/0000-0003-4742-3679","observed_orcids":["https://orcid.org/0000-0003-4742-3679"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Andrea Califano","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5025125161","display_name":"Michael M. Shen","orcid":"https://orcid.org/0000-0002-4042-1657","observed_orcids":["https://orcid.org/0000-0002-4042-1657"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Michael M. Shen","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"last","author":{"id":"https://openalex.org/A5033587895","display_name":"Cory T. Abate-Shen","orcid":"https://orcid.org/0000-0002-5021-0570","observed_orcids":["https://orcid.org/0000-0002-5021-0570"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Cory Abate-Shen","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]}],"institutions":[],"countries_distinct_count":0,"institutions_distinct_count":0,"corresponding_author_ids":[],"corresponding_institution_ids":[],"apc_list":null,"apc_paid":null,"fwci":null,"has_fulltext":false,"cited_by_count":0,"citation_normalized_percentile":null,"cited_by_percentile_year":null,"biblio":{"volume":null,"issue":null,"first_page":null,"last_page":null},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10952","display_name":"PI3K/AKT/mTOR signaling in cancer","score":0.5083000063896179,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T10952","display_name":"PI3K/AKT/mTOR signaling in cancer","score":0.5083000063896179,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10543","display_name":"Prostate Cancer Treatment and Research","score":0.49000000953674316,"subfield":{"id":"https://openalex.org/subfields/2740","display_name":"Pulmonary and Respiratory Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T12465","display_name":"Cancer, Lipids, and Metabolism","score":0.00019999999494757503,"subfield":{"id":"https://openalex.org/subfields/1306","display_name":"Cancer Research"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/akt-mtor-signaling-pathway","display_name":"Akt/mTOR signaling","score":0.9660000205039978},{"id":"https://openalex.org/keywords/dual-targeting","display_name":"dual targeting","score":0.7680000066757202},{"id":"https://openalex.org/keywords/castration-resistant-prostate-cancer","display_name":"castration-resistant prostate cancer","score":0.9980000257492065},{"id":"https://openalex.org/keywords/genetically-engineered-mouse-models","display_name":"genetically engineered mouse models","score":0.8849999904632568},{"id":"https://openalex.org/keywords/gene-set-enrichment-analysis","display_name":"gene set enrichment analysis","score":0.8399999737739563},{"id":"https://openalex.org/keywords/castration","display_name":"castration","score":0.8090000152587891}],"concepts":[{"id":"https://openalex.org/C2780192828","wikidata":"https://www.wikidata.org/wiki/Q181257","display_name":"Prostate cancer","level":3,"score":0.7531744241714478},{"id":"https://openalex.org/C86554907","wikidata":"https://www.wikidata.org/wiki/Q285613","display_name":"PI3K/AKT/mTOR pathway","level":3,"score":0.6747289896011353},{"id":"https://openalex.org/C75217442","wikidata":"https://www.wikidata.org/wiki/Q423650","display_name":"Protein kinase B","level":3,"score":0.6338008046150208},{"id":"https://openalex.org/C2779256933","wikidata":"https://www.wikidata.org/wiki/Q58929","display_name":"Castration","level":3,"score":0.5888720154762268},{"id":"https://openalex.org/C502942594","wikidata":"https://www.wikidata.org/wiki/Q3421914","display_name":"Cancer research","level":1,"score":0.5833359360694885},{"id":"https://openalex.org/C45235069","wikidata":"https://www.wikidata.org/wiki/Q278425","display_name":"Table (database)","level":2,"score":0.4385099709033966},{"id":"https://openalex.org/C3019111730","wikidata":"https://www.wikidata.org/wiki/Q159236","display_name":"Genetically engineered","level":3,"score":0.42966726422309875},{"id":"https://openalex.org/C62478195","wikidata":"https://www.wikidata.org/wiki/Q828130","display_name":"Signal transduction","level":2,"score":0.4117697477340698},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.38548988103866577},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.3137264549732208},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.29590028524398804},{"id":"https://openalex.org/C134018914","wikidata":"https://www.wikidata.org/wiki/Q162606","display_name":"Endocrinology","level":1,"score":0.2843339741230011},{"id":"https://openalex.org/C121608353","wikidata":"https://www.wikidata.org/wiki/Q12078","display_name":"Cancer","level":2,"score":0.27461591362953186},{"id":"https://openalex.org/C95444343","wikidata":"https://www.wikidata.org/wiki/Q7141","display_name":"Cell biology","level":1,"score":0.27214789390563965},{"id":"https://openalex.org/C104317684","wikidata":"https://www.wikidata.org/wiki/Q7187","display_name":"Gene","level":2,"score":0.24594464898109436},{"id":"https://openalex.org/C54355233","wikidata":"https://www.wikidata.org/wiki/Q7162","display_name":"Genetics","level":1,"score":0.1796557605266571},{"id":"https://openalex.org/C41008148","wikidata":"https://www.wikidata.org/wiki/Q21198","display_name":"Computer science","level":0,"score":0.13689029216766357},{"id":"https://openalex.org/C71315377","wikidata":"https://www.wikidata.org/wiki/Q11364","display_name":"Hormone","level":2,"score":0.07005801796913147},{"id":"https://openalex.org/C77088390","wikidata":"https://www.wikidata.org/wiki/Q8513","display_name":"Database","level":1,"score":0.06088283658027649}],"mesh":[],"locations_count":3,"locations":[{"id":"doi:10.1158/0008-5472.22393620","doi":"https://doi.org/10.1158/0008-5472.22393620","is_oa":true,"landing_page_url":"http://dx.doi.org/10.1158/0008-5472.22393620","pdf_url":null,"source":null,"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"acceptedVersion","is_accepted":true,"is_published":false,"raw_source_name":"American Association for Cancer Research","raw_type":"posted-content"},{"id":"doi:10.1158/0008-5472.22393620.v1","doi":"https://doi.org/10.1158/0008-5472.22393620.v1","is_oa":true,"landing_page_url":"http://dx.doi.org/10.1158/0008-5472.22393620.v1","pdf_url":null,"source":null,"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"acceptedVersion","is_accepted":true,"is_published":false,"raw_source_name":"American Association for Cancer Research","raw_type":"posted-content"},{"id":"pmh:oai:figshare.com:article/22393620","doi":null,"is_oa":true,"landing_page_url":"https://figshare.com/articles/journal_contribution/Supplementary_Table_7_from_Dual_Targeting_of_the_Akt_mTOR_Signaling_Pathway_Inhibits_Castration-Resistant_Prostate_Cancer_in_a_Genetically_Engineered_Mouse_Model/22393620","pdf_url":null,"source":{"id":"https://openalex.org/S4377196282","display_name":"Figshare","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I4210132348","host_organization_name":"Figshare (United Kingdom)","host_organization_lineage":["https://openalex.org/I4210132348"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"","raw_type":"Text"}],"best_oa_location":{"id":"doi:10.1158/0008-5472.22393620","doi":"https://doi.org/10.1158/0008-5472.22393620","is_oa":true,"landing_page_url":"http://dx.doi.org/10.1158/0008-5472.22393620","pdf_url":null,"source":null,"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"acceptedVersion","is_accepted":true,"is_published":false,"raw_source_name":"American Association for Cancer Research","raw_type":"posted-content"},"sustainable_development_goals":[{"score":0.8560000061988831,"display_name":"Good health and well-being","id":"https://metadata.un.org/sdg/3"}],"study_designs":[],"awards":[],"funders":[],"has_content":{"pdf":false,"grobid_xml":false},"content_urls":null,"referenced_works_count":0,"referenced_works":[],"related_works":["https://openalex.org/W4362524019","https://openalex.org/W4392686101","https://openalex.org/W2117433522","https://openalex.org/W2071548012","https://openalex.org/W7097933876","https://openalex.org/W7145336219","https://openalex.org/W7098692073","https://openalex.org/W2563494387","https://openalex.org/W1577578562","https://openalex.org/W2324138482"],"abstract_inverted_index":{"DOC":[0],"file,":[1],"347K,":[2],"GSEA":[3],"data":[4],"for":[5],"the":[6],"castrated":[7],"mice.":[8]},"counts_by_year":[],"updated_date":"2026-11-04T10:54:05.112534","created_date":"2023-04-05T00:00:00"}