{"id":"https://openalex.org/W4361972267","doi":"https://doi.org/10.1158/0008-5472.22411776","title":"Supplementary Table S1 from Lurbinectedin Inactivates the Ewing Sarcoma Oncoprotein EWS-FLI1 by Redistributing It within the Nucleus","display_name":"Supplementary Table S1 from Lurbinectedin Inactivates the Ewing Sarcoma Oncoprotein EWS-FLI1 by Redistributing It within the Nucleus","publication_year":2023,"publication_date":"2023-03-31","ids":{"openalex":"https://openalex.org/W4361972267","doi":"https://doi.org/10.1158/0008-5472.22411776"},"language":"en","primary_location":{"id":"doi:10.1158/0008-5472.22411776","doi":"https://doi.org/10.1158/0008-5472.22411776","is_oa":true,"landing_page_url":"https://doi.org/10.1158/0008-5472.22411776","pdf_url":null,"source":null,"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"acceptedVersion","is_accepted":true,"is_published":false,"raw_source_name":"American Association for Cancer Research","raw_type":"posted-content"},"volume":null,"type":"supplementary-materials","indexed_in":["crossref"],"open_access":{"is_oa":true,"oa_status":"gold","oa_url":"https://doi.org/10.1158/0008-5472.22411776","any_repository_has_fulltext":null},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5046148050","display_name":"Matt L. Harlow","orcid":"https://orcid.org/0000-0002-1860-0720","observed_orcids":["https://orcid.org/0000-0002-1860-0720"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Matt L. Harlow","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5065627176","display_name":"Nichole Maloney","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Nichole Maloney","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5038262486","display_name":"Joseph T. Roland","orcid":"https://orcid.org/0000-0001-9977-0520","observed_orcids":["https://orcid.org/0000-0001-9977-0520"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Joseph Roland","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5074546909","display_name":"Maria Jose Guill\u00e9n Navarro","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Maria Jose Guillen Navarro","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5026842186","display_name":"Matthew K. Easton","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Matthew K. Easton","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5065580138","display_name":"Susan M. Kitchen-Goosen","orcid":"https://orcid.org/0000-0001-9291-056X","observed_orcids":["https://orcid.org/0000-0001-9291-056X"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Susan M. Kitchen-Goosen","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5033838605","display_name":"Elissa A. Boguslawski","orcid":"https://orcid.org/0000-0003-4233-903X","observed_orcids":["https://orcid.org/0000-0003-4233-903X"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Elissa A. Boguslawski","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5026553060","display_name":"Zachary Madaj","orcid":"https://orcid.org/0000-0003-2330-0500","observed_orcids":["https://orcid.org/0000-0003-2330-0500"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Zachary B. Madaj","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5076650409","display_name":"Ben K. Johnson","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Ben K. Johnson","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5042183327","display_name":"Megan J. Bowman","orcid":"https://orcid.org/0000-0001-5742-1779","observed_orcids":["https://orcid.org/0000-0001-5742-1779"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Megan J. Bowman","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5055703421","display_name":"Maurizio D\u2019Incalci","orcid":"https://orcid.org/0000-0001-8784-1360","observed_orcids":["https://orcid.org/0000-0001-8784-1360"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Maurizio D'Incalci","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5111528341","display_name":"Mary E. Winn","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Mary E. Winn","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":null,"display_name":"Lisa Turner","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Lisa Turner","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5062941900","display_name":"Galen H. Hostetter","orcid":"https://orcid.org/0000-0003-2616-6861","observed_orcids":["https://orcid.org/0000-0003-2616-6861"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Galen Hostetter","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5067025614","display_name":"Carlos Mar\u00eda Galmarini","orcid":"https://orcid.org/0000-0001-5494-6617","observed_orcids":["https://orcid.org/0000-0001-5494-6617","https://orcid.org/0000-0003-3361-217X"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Carlos Mar\u00eda Galmarini","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5108298552","display_name":"Pablo M. Aviles","orcid":"https://orcid.org/0000-0001-7922-6042","observed_orcids":["https://orcid.org/0000-0001-7922-6042"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Pablo M. Aviles","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"last","author":{"id":"https://openalex.org/A5028721392","display_name":"Patrick Joseph Grohar","orcid":"https://orcid.org/0000-0002-1071-4563","observed_orcids":["https://orcid.org/0000-0002-1071-4563"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Patrick J. Grohar","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]}],"institutions":[],"countries_distinct_count":0,"institutions_distinct_count":0,"corresponding_author_ids":[],"corresponding_institution_ids":[],"apc_list":null,"apc_paid":null,"fwci":null,"has_fulltext":false,"cited_by_count":0,"citation_normalized_percentile":null,"cited_by_percentile_year":null,"biblio":{"volume":null,"issue":null,"first_page":null,"last_page":null},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10253","display_name":"Sarcoma Diagnosis and Treatment","score":0.9839000105857849,"subfield":{"id":"https://openalex.org/subfields/2740","display_name":"Pulmonary and Respiratory Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T10253","display_name":"Sarcoma Diagnosis and Treatment","score":0.9839000105857849,"subfield":{"id":"https://openalex.org/subfields/2740","display_name":"Pulmonary and Respiratory Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10583","display_name":"Cancer-related Molecular Pathways","score":0.00279999990016222,"subfield":{"id":"https://openalex.org/subfields/2730","display_name":"Oncology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T12820","display_name":"Chromatin Remodeling and Cancer","score":0.0008999999845400453,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/lurbinectedin","display_name":"lurbinectedin","score":0.9919999837875366},{"id":"https://openalex.org/keywords/ews-fli1","display_name":"EWS-FLI1","score":0.9100000262260437},{"id":"https://openalex.org/keywords/ewing-sarcoma","display_name":"Ewing sarcoma","score":0.9959999918937683},{"id":"https://openalex.org/keywords/primers","display_name":"primer sequences","score":0.8370000123977661}],"concepts":[{"id":"https://openalex.org/C45235069","wikidata":"https://www.wikidata.org/wiki/Q278425","display_name":"Table (database)","level":2,"score":0.7418506741523743},{"id":"https://openalex.org/C2778256501","wikidata":"https://www.wikidata.org/wiki/Q223911","display_name":"Sarcoma","level":2,"score":0.5575119256973267},{"id":"https://openalex.org/C2780723820","wikidata":"https://www.wikidata.org/wiki/Q1934178","display_name":"Nucleus","level":2,"score":0.4965282082557678},{"id":"https://openalex.org/C2777586341","wikidata":"https://www.wikidata.org/wiki/Q1138580","display_name":"Ewing's sarcoma","level":3,"score":0.4296039342880249},{"id":"https://openalex.org/C502942594","wikidata":"https://www.wikidata.org/wiki/Q3421914","display_name":"Cancer research","level":1,"score":0.35705024003982544},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.3405524492263794},{"id":"https://openalex.org/C41008148","wikidata":"https://www.wikidata.org/wiki/Q21198","display_name":"Computer science","level":0,"score":0.24416863918304443},{"id":"https://openalex.org/C95444343","wikidata":"https://www.wikidata.org/wiki/Q7141","display_name":"Cell biology","level":1,"score":0.19164115190505981},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.1655319631099701},{"id":"https://openalex.org/C124101348","wikidata":"https://www.wikidata.org/wiki/Q172491","display_name":"Data mining","level":1,"score":0.08664712309837341},{"id":"https://openalex.org/C142724271","wikidata":"https://www.wikidata.org/wiki/Q7208","display_name":"Pathology","level":1,"score":0.050041526556015015}],"mesh":[],"locations_count":2,"locations":[{"id":"doi:10.1158/0008-5472.22411776","doi":"https://doi.org/10.1158/0008-5472.22411776","is_oa":true,"landing_page_url":"https://doi.org/10.1158/0008-5472.22411776","pdf_url":null,"source":null,"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"acceptedVersion","is_accepted":true,"is_published":false,"raw_source_name":"American Association for Cancer Research","raw_type":"posted-content"},{"id":"doi:10.1158/0008-5472.22411776.v1","doi":"https://doi.org/10.1158/0008-5472.22411776.v1","is_oa":true,"landing_page_url":"https://doi.org/10.1158/0008-5472.22411776.v1","pdf_url":null,"source":null,"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"acceptedVersion","is_accepted":true,"is_published":false,"raw_source_name":"American Association for Cancer Research","raw_type":"posted-content"}],"best_oa_location":{"id":"doi:10.1158/0008-5472.22411776","doi":"https://doi.org/10.1158/0008-5472.22411776","is_oa":true,"landing_page_url":"https://doi.org/10.1158/0008-5472.22411776","pdf_url":null,"source":null,"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"acceptedVersion","is_accepted":true,"is_published":false,"raw_source_name":"American Association for Cancer Research","raw_type":"posted-content"},"sustainable_development_goals":[{"score":0.4043000042438507,"id":"https://metadata.un.org/sdg/3","display_name":"Good health and well-being"}],"study_designs":[],"awards":[],"funders":[],"has_content":{"pdf":false,"grobid_xml":false},"content_urls":null,"referenced_works_count":0,"referenced_works":[],"related_works":["https://openalex.org/W2529120334","https://openalex.org/W4361823772","https://openalex.org/W7148754143","https://openalex.org/W4393073053","https://openalex.org/W6941259861","https://openalex.org/W4240786408","https://openalex.org/W6941459794","https://openalex.org/W6967169264","https://openalex.org/W2605788282","https://openalex.org/W2300040080"],"abstract_inverted_index":{"Supplementary":[0],"Table":[1],"S1":[2],"Sequences":[3],"of":[4],"primers":[5],"used":[6],"in":[7],"the":[8],"study.":[9]},"counts_by_year":[],"updated_date":"2026-11-04T10:54:05.112534","created_date":"2023-04-05T00:00:00"}