{"id":"https://openalex.org/W4361962780","doi":"https://doi.org/10.1158/1078-0432.22488453","title":"Supplementary Tables S1-5 from Serologic Profiling Using an Epstein-Barr Virus Mammalian Expression Library Identifies EBNA1 IgA as a Prediagnostic Marker for Nasopharyngeal Carcinoma","display_name":"Supplementary Tables S1-5 from Serologic Profiling Using an Epstein-Barr Virus Mammalian Expression Library Identifies EBNA1 IgA as a Prediagnostic Marker for Nasopharyngeal Carcinoma","publication_year":2023,"publication_date":"2023-04-01","ids":{"openalex":"https://openalex.org/W4361962780","doi":"https://doi.org/10.1158/1078-0432.22488453"},"language":"en","primary_location":{"id":"doi:10.1158/1078-0432.22488453","doi":"https://doi.org/10.1158/1078-0432.22488453","is_oa":true,"landing_page_url":"https://doi.org/10.1158/1078-0432.22488453","pdf_url":null,"source":null,"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"acceptedVersion","is_accepted":true,"is_published":false,"raw_source_name":"American Association for Cancer Research","raw_type":"posted-content"},"volume":null,"type":"supplementary-materials","indexed_in":["crossref"],"open_access":{"is_oa":true,"oa_status":"gold","oa_url":"https://doi.org/10.1158/1078-0432.22488453","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5051135654","display_name":"Sarita Paudel","orcid":"https://orcid.org/0000-0002-5041-0521","observed_orcids":["https://orcid.org/0000-0002-5041-0521"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Sarita Paudel","raw_affiliation_strings":[],"raw_orcid":"https://orcid.org/0000-0002-5041-0521","affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5087885661","display_name":"Benjamin E. Warner","orcid":"https://orcid.org/0000-0002-1550-1516","observed_orcids":["https://orcid.org/0000-0002-1550-1516"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Benjamin E. Warner","raw_affiliation_strings":[],"raw_orcid":"https://orcid.org/0000-0002-1550-1516","affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5063230233","display_name":"Renwei Wang","orcid":"https://orcid.org/0000-0001-8871-7054","observed_orcids":["https://orcid.org/0000-0001-8871-7054"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Renwei Wang","raw_affiliation_strings":[],"raw_orcid":"https://orcid.org/0000-0001-8871-7054","affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5068308715","display_name":"Jennifer\u00a0M. Adams\u2010Haduch","orcid":"https://orcid.org/0000-0002-0640-3076","observed_orcids":["https://orcid.org/0000-0002-0640-3076"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Jennifer Adams-Haduch","raw_affiliation_strings":[],"raw_orcid":"https://orcid.org/0000-0002-0640-3076","affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5013884255","display_name":"Alex S. Reznik","orcid":"https://orcid.org/0000-0001-8993-8617","observed_orcids":["https://orcid.org/0000-0001-8993-8617"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Alex S. Reznik","raw_affiliation_strings":[],"raw_orcid":"https://orcid.org/0000-0001-8993-8617","affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5009311791","display_name":"Jason Dou","orcid":"https://orcid.org/0000-0002-8960-4200","observed_orcids":["https://orcid.org/0000-0002-8960-4200"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Jason Dou","raw_affiliation_strings":[],"raw_orcid":"https://orcid.org/0000-0002-8960-4200","affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5068887242","display_name":"Yufei Huang","orcid":"https://orcid.org/0000-0001-6268-5357","observed_orcids":["https://orcid.org/0000-0001-6268-5357"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Yufei Huang","raw_affiliation_strings":[],"raw_orcid":"https://orcid.org/0000-0001-6268-5357","affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5080361653","display_name":"Yu\u2010Tang Gao","orcid":"https://orcid.org/0000-0003-3904-1777","observed_orcids":["https://orcid.org/0000-0003-3904-1777"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Yu-Tang Gao","raw_affiliation_strings":[],"raw_orcid":"https://orcid.org/0000-0003-3904-1777","affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5019713852","display_name":"Woon\u2010Puay Koh","orcid":"https://orcid.org/0000-0002-5674-6341","observed_orcids":["https://orcid.org/0000-0002-5674-6341"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Woon-Puay Koh","raw_affiliation_strings":[],"raw_orcid":"https://orcid.org/0000-0002-5674-6341","affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5077062549","display_name":"Alan B\u00e4ckerholm","orcid":"https://orcid.org/0000-0002-8590-1195","observed_orcids":["https://orcid.org/0000-0002-8590-1195"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Alan B\u00e4ckerholm","raw_affiliation_strings":[],"raw_orcid":"https://orcid.org/0000-0002-8590-1195","affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5081606775","display_name":"Jian\u2010Min Yuan","orcid":"https://orcid.org/0000-0002-4620-3108","observed_orcids":["https://orcid.org/0000-0002-4620-3108"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Jian-Min Yuan","raw_affiliation_strings":[],"raw_orcid":"https://orcid.org/0000-0002-4620-3108","affiliations":[]},{"author_position":"last","author":{"id":"https://openalex.org/A5078828367","display_name":"Kathy H.Y. Shair","orcid":"https://orcid.org/0000-0002-9556-1745","observed_orcids":["https://orcid.org/0000-0002-9556-1745"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Kathy H.Y. Shair","raw_affiliation_strings":[],"raw_orcid":"https://orcid.org/0000-0002-9556-1745","affiliations":[]}],"institutions":[],"countries_distinct_count":0,"institutions_distinct_count":0,"corresponding_author_ids":[],"corresponding_institution_ids":[],"apc_list":null,"apc_paid":null,"fwci":null,"has_fulltext":false,"cited_by_count":0,"citation_normalized_percentile":null,"cited_by_percentile_year":null,"biblio":{"volume":null,"issue":null,"first_page":null,"last_page":null},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10685","display_name":"Viral-associated cancers and disorders","score":0.9702000021934509,"subfield":{"id":"https://openalex.org/subfields/2730","display_name":"Oncology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T10685","display_name":"Viral-associated cancers and disorders","score":0.9702000021934509,"subfield":{"id":"https://openalex.org/subfields/2730","display_name":"Oncology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10307","display_name":"Head and Neck Cancer Studies","score":0.024299999698996544,"subfield":{"id":"https://openalex.org/subfields/2733","display_name":"Otorhinolaryngology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10340","display_name":"Hepatitis B Virus Studies","score":0.0003000000142492354,"subfield":{"id":"https://openalex.org/subfields/2713","display_name":"Epidemiology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/nasopharyngeal-carcinoma","display_name":"nasopharyngeal carcinoma","score":0.9580000042915344},{"id":"https://openalex.org/keywords/epstein-barr-virus","display_name":"Epstein-Barr virus","score":0.9649999737739563},{"id":"https://openalex.org/keywords/ebna1","display_name":"EBNA1","score":0.925000011920929},{"id":"https://openalex.org/keywords/iga-antibodies","display_name":"IgA antibodies","score":0.7990000247955322},{"id":"https://openalex.org/keywords/pre-diagnostic-biomarkers","display_name":"pre-diagnostic biomarkers","score":0.8629999756813049},{"id":"https://openalex.org/keywords/cancer-prediction","display_name":"cancer prediction","score":0.3529999852180481}],"concepts":[{"id":"https://openalex.org/C2778997737","wikidata":"https://www.wikidata.org/wiki/Q1693598","display_name":"Nasopharyngeal carcinoma","level":3,"score":0.9319052696228027},{"id":"https://openalex.org/C2781375147","wikidata":"https://www.wikidata.org/wiki/Q6900","display_name":"Epstein\u2013Barr virus","level":3,"score":0.5676746964454651},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.5166400074958801},{"id":"https://openalex.org/C72563966","wikidata":"https://www.wikidata.org/wiki/Q1303415","display_name":"Cohort","level":2,"score":0.48747944831848145},{"id":"https://openalex.org/C45189115","wikidata":"https://www.wikidata.org/wiki/Q502159","display_name":"Serology","level":3,"score":0.4751543700695038},{"id":"https://openalex.org/C2522874641","wikidata":"https://www.wikidata.org/wiki/Q808","display_name":"Virus","level":2,"score":0.4327058792114258},{"id":"https://openalex.org/C143998085","wikidata":"https://www.wikidata.org/wiki/Q162555","display_name":"Oncology","level":1,"score":0.40065523982048035},{"id":"https://openalex.org/C159047783","wikidata":"https://www.wikidata.org/wiki/Q7215","display_name":"Virology","level":1,"score":0.3433464765548706},{"id":"https://openalex.org/C203014093","wikidata":"https://www.wikidata.org/wiki/Q101929","display_name":"Immunology","level":1,"score":0.34021908044815063},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.2796778380870819},{"id":"https://openalex.org/C159654299","wikidata":"https://www.wikidata.org/wiki/Q79460","display_name":"Antibody","level":2,"score":0.22780320048332214},{"id":"https://openalex.org/C509974204","wikidata":"https://www.wikidata.org/wiki/Q180507","display_name":"Radiation therapy","level":2,"score":0.0}],"mesh":[],"locations_count":3,"locations":[{"id":"doi:10.1158/1078-0432.22488453","doi":"https://doi.org/10.1158/1078-0432.22488453","is_oa":true,"landing_page_url":"https://doi.org/10.1158/1078-0432.22488453","pdf_url":null,"source":null,"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"acceptedVersion","is_accepted":true,"is_published":false,"raw_source_name":"American Association for Cancer Research","raw_type":"posted-content"},{"id":"doi:10.1158/1078-0432.22488453.v1","doi":"https://doi.org/10.1158/1078-0432.22488453.v1","is_oa":true,"landing_page_url":"https://doi.org/10.1158/1078-0432.22488453.v1","pdf_url":null,"source":null,"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"acceptedVersion","is_accepted":true,"is_published":false,"raw_source_name":"American Association for Cancer Research","raw_type":"posted-content"},{"id":"pmh:oai:figshare.com:article/22488453","doi":null,"is_oa":true,"landing_page_url":"https://figshare.com/articles/journal_contribution/Supplementary_Tables_S1-5_from_Serologic_Profiling_Using_an_Epstein-Barr_Virus_Mammalian_Expression_Library_Identifies_EBNA1_IgA_as_a_Prediagnostic_Marker_for_Nasopharyngeal_Carcinoma/22488453","pdf_url":null,"source":{"id":"https://openalex.org/S4377196282","display_name":"Figshare","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I4210132348","host_organization_name":"Figshare (United Kingdom)","host_organization_lineage":["https://openalex.org/I4210132348"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"","raw_type":"Text"}],"best_oa_location":{"id":"doi:10.1158/1078-0432.22488453","doi":"https://doi.org/10.1158/1078-0432.22488453","is_oa":true,"landing_page_url":"https://doi.org/10.1158/1078-0432.22488453","pdf_url":null,"source":null,"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"acceptedVersion","is_accepted":true,"is_published":false,"raw_source_name":"American Association for Cancer Research","raw_type":"posted-content"},"sustainable_development_goals":[{"id":"https://metadata.un.org/sdg/3","display_name":"Good health and well-being","score":1.0}],"study_designs":[],"awards":[],"funders":[],"has_content":{"pdf":false,"grobid_xml":false},"content_urls":null,"referenced_works_count":0,"referenced_works":[],"related_works":["https://openalex.org/W4361950527","https://openalex.org/W4297266637","https://openalex.org/W4400642553","https://openalex.org/W4404423320","https://openalex.org/W3048529014","https://openalex.org/W2042193480","https://openalex.org/W2741129234","https://openalex.org/W4361948541","https://openalex.org/W4362480788","https://openalex.org/W4402488512"],"abstract_inverted_index":{"Table":[0,32,38,51,64],"S1.":[1],"Baseline":[2],"demographic":[3],"and":[4,15,27,100],"lifestyle":[5],"characteristics":[6],"of":[7,45,58,67,87],"study":[8],"participants":[9],"who":[10,17],"developed":[11],"nasopharyngeal":[12],"carcinoma":[13],"(cases)":[14],"those":[16],"remained":[18],"cancer":[19],"free":[20],"(controls),":[21],"the":[22,28,75,78,94,101],"Singapore":[23,95],"Chinse":[24],"Health":[25,97],"Study":[26,98,104],"Shanghai":[29,102],"Cohort":[30,103],"Study;":[31],"S2.":[33],"EBV":[34,48,61],"ORF":[35,49,62],"Expression":[36],"Library;":[37],"S3.":[39],"Anti-EBV":[40,53],"IgA":[41,69],"prediction":[42,55],"or":[43,56],"protection":[44,57],"NPC":[46,59,71],"by":[47,60],"class;":[50,63],"S4.":[52],"IgG":[54],"S5.":[65],"Detection":[66],"EBNA1":[68],"in":[70,93],"cases":[72],"sorted":[73],"from":[74,82],"shortest":[76],"to":[77,85],"longest":[79],"time":[80],"interval":[81],"blood":[83],"collection":[84],"diagnosis":[86],"NPC,":[88],"along":[89],"with":[90],"matched":[91],"controls":[92],"Chinese":[96],"(SCHS)":[99],"(SCS).":[105]},"counts_by_year":[],"updated_date":"2026-11-04T10:54:05.112534","created_date":"2023-04-05T00:00:00"}