{"id":"https://openalex.org/W4361908202","doi":"https://doi.org/10.1158/1078-0432.22450671.v1","title":"Supplementary Figure 2 from Deciphering the Mechanisms of Tumorigenesis in Human Pancreatic Ductal Epithelial Cells","display_name":"Supplementary Figure 2 from Deciphering the Mechanisms of Tumorigenesis in Human Pancreatic Ductal Epithelial Cells","publication_year":2023,"publication_date":"2023-03-31","ids":{"openalex":"https://openalex.org/W4361908202","doi":"https://doi.org/10.1158/1078-0432.22450671.v1"},"language":"en","primary_location":{"id":"doi:10.1158/1078-0432.22450671.v1","doi":"https://doi.org/10.1158/1078-0432.22450671.v1","is_oa":true,"landing_page_url":"https://doi.org/10.1158/1078-0432.22450671.v1","pdf_url":"https://aacr.figshare.com/articles/journal_contribution/Supplementary_Figure_2_from_Deciphering_the_Mechanisms_of_Tumorigenesis_in_Human_Pancreatic_Ductal_Epithelial_Cells/22450671/1/files/39901749.pdf","source":null,"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"acceptedVersion","is_accepted":true,"is_published":false,"raw_source_name":"American Association for Cancer Research","raw_type":"posted-content"},"volume":null,"type":"supplementary-materials","indexed_in":["crossref"],"open_access":{"is_oa":true,"oa_status":"gold","oa_url":"https://aacr.figshare.com/articles/journal_contribution/Supplementary_Figure_2_from_Deciphering_the_Mechanisms_of_Tumorigenesis_in_Human_Pancreatic_Ductal_Epithelial_Cells/22450671/1/files/39901749.pdf","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":null,"display_name":"Zhe Chang","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Zhe Chang","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5091694797","display_name":"Zhongkui Li","orcid":"https://orcid.org/0000-0002-9361-4305","observed_orcids":["https://orcid.org/0000-0002-9361-4305"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Zhongkui Li","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5100381791","display_name":"Xiaoyan Wang","orcid":"https://orcid.org/0000-0002-7281-1078","observed_orcids":["https://orcid.org/0000-0002-7281-1078","https://orcid.org/0000-0002-7520-541X"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Xiaoyang Wang","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5054388259","display_name":"Ya\u2019an Kang","orcid":"https://orcid.org/0000-0002-2076-3692","observed_orcids":["https://orcid.org/0000-0002-2076-3692"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Ya'an Kang","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5002034669","display_name":"Yuhui Yuan","orcid":"https://orcid.org/0000-0002-7109-6703","observed_orcids":["https://orcid.org/0000-0002-7109-6703"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Yuhui Yuan","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5035853822","display_name":"Jiangong Niu","orcid":"https://orcid.org/0000-0001-5643-5490","observed_orcids":["https://orcid.org/0000-0001-5643-5490"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Jiangong Niu","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5101758546","display_name":"Huamin Wang","orcid":"https://orcid.org/0000-0002-2038-5863","observed_orcids":["https://orcid.org/0000-0002-2038-5863"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Huamin Wang","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5072825310","display_name":"Deyali Chatterjee","orcid":"https://orcid.org/0000-0002-3322-1163","observed_orcids":["https://orcid.org/0000-0002-3322-1163"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Deyali Chatterjee","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5037694904","display_name":"Jason B. Fleming","orcid":"https://orcid.org/0000-0002-8796-5627","observed_orcids":["https://orcid.org/0000-0002-8796-5627"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Jason B. Fleming","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5100643214","display_name":"Min Li","orcid":"https://orcid.org/0000-0003-1350-9909","observed_orcids":["https://orcid.org/0000-0003-1350-9909"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Min Li","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5087376683","display_name":"James L. Abbruzzese","orcid":"https://orcid.org/0000-0001-9223-2965","observed_orcids":["https://orcid.org/0000-0001-9223-2965"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"James L. Abbruzzese","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"last","author":{"id":"https://openalex.org/A5068301962","display_name":"Paul J. Chiao","orcid":"https://orcid.org/0000-0001-7003-6605","observed_orcids":["https://orcid.org/0000-0001-7003-6605"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Paul J. Chiao","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]}],"institutions":[],"countries_distinct_count":0,"institutions_distinct_count":0,"corresponding_author_ids":[],"corresponding_institution_ids":[],"apc_list":null,"apc_paid":null,"fwci":null,"has_fulltext":false,"cited_by_count":0,"citation_normalized_percentile":null,"cited_by_percentile_year":null,"biblio":{"volume":null,"issue":null,"first_page":null,"last_page":null},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10231","display_name":"Pancreatic and Hepatic Oncology Research","score":0.9833999872207642,"subfield":{"id":"https://openalex.org/subfields/2730","display_name":"Oncology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T10231","display_name":"Pancreatic and Hepatic Oncology Research","score":0.9833999872207642,"subfield":{"id":"https://openalex.org/subfields/2730","display_name":"Oncology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10169","display_name":"Protein Kinase Regulation and GTPase Signaling","score":0.0032999999821186066,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T11501","display_name":"TGF-\u03b2 signaling in diseases","score":0.0015999999595806003,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/pancreatic-ductal-cells","display_name":"pancreatic ductal cells","score":0.8700000047683716},{"id":"https://openalex.org/keywords/carcinogenesis","display_name":"carcinogenesis","score":0.9190000295639038},{"id":"https://openalex.org/keywords/cell-migration","display_name":"cell migration","score":0.8669999837875366},{"id":"https://openalex.org/keywords/cell-invasion","display_name":"cell invasion","score":0.9919999837875366},{"id":"https://openalex.org/keywords/kras-mutation","display_name":"KRAS mutation","score":0.7770000100135803},{"id":"https://openalex.org/keywords/her2","display_name":"HER2","score":0.7879999876022339},{"id":"https://openalex.org/keywords/p16","display_name":"p16","score":0.9810000061988831},{"id":"https://openalex.org/keywords/p14","display_name":"p14","score":0.8209999799728394},{"id":"https://openalex.org/keywords/smad4","display_name":"SMAD4","score":0.9700000286102295},{"id":"https://openalex.org/keywords/shrna-knockdown","display_name":"shRNA knockdown","score":0.871999979019165}],"concepts":[{"id":"https://openalex.org/C555283112","wikidata":"https://www.wikidata.org/wiki/Q1637543","display_name":"Carcinogenesis","level":3,"score":0.627257764339447},{"id":"https://openalex.org/C3020076753","wikidata":"https://www.wikidata.org/wiki/Q212961","display_name":"Pancreatic carcinoma","level":4,"score":0.4753427505493164},{"id":"https://openalex.org/C2992026798","wikidata":"https://www.wikidata.org/wiki/Q212961","display_name":"Pancreatic ductal adenocarcinoma","level":4,"score":0.47106096148490906},{"id":"https://openalex.org/C502942594","wikidata":"https://www.wikidata.org/wiki/Q3421914","display_name":"Cancer research","level":1,"score":0.4363860487937927},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.3747386336326599},{"id":"https://openalex.org/C142724271","wikidata":"https://www.wikidata.org/wiki/Q7208","display_name":"Pathology","level":1,"score":0.32684779167175293},{"id":"https://openalex.org/C95444343","wikidata":"https://www.wikidata.org/wiki/Q7141","display_name":"Cell biology","level":1,"score":0.3266730308532715},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.3188821077346802},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.24176934361457825},{"id":"https://openalex.org/C2780210213","wikidata":"https://www.wikidata.org/wiki/Q212961","display_name":"Pancreatic cancer","level":3,"score":0.18293100595474243},{"id":"https://openalex.org/C121608353","wikidata":"https://www.wikidata.org/wiki/Q12078","display_name":"Cancer","level":2,"score":0.07228526473045349}],"mesh":[],"locations_count":2,"locations":[{"id":"doi:10.1158/1078-0432.22450671.v1","doi":"https://doi.org/10.1158/1078-0432.22450671.v1","is_oa":true,"landing_page_url":"https://doi.org/10.1158/1078-0432.22450671.v1","pdf_url":"https://aacr.figshare.com/articles/journal_contribution/Supplementary_Figure_2_from_Deciphering_the_Mechanisms_of_Tumorigenesis_in_Human_Pancreatic_Ductal_Epithelial_Cells/22450671/1/files/39901749.pdf","source":null,"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"acceptedVersion","is_accepted":true,"is_published":false,"raw_source_name":"American Association for Cancer Research","raw_type":"posted-content"},{"id":"pmh:oai:figshare.com:article/22450671","doi":null,"is_oa":true,"landing_page_url":"https://figshare.com/articles/journal_contribution/Supplementary_Figure_2_from_Deciphering_the_Mechanisms_of_Tumorigenesis_in_Human_Pancreatic_Ductal_Epithelial_Cells/22450671","pdf_url":null,"source":{"id":"https://openalex.org/S4377196282","display_name":"Figshare","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I4210132348","host_organization_name":"Figshare (United Kingdom)","host_organization_lineage":["https://openalex.org/I4210132348"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"","raw_type":"Text"}],"best_oa_location":{"id":"doi:10.1158/1078-0432.22450671.v1","doi":"https://doi.org/10.1158/1078-0432.22450671.v1","is_oa":true,"landing_page_url":"https://doi.org/10.1158/1078-0432.22450671.v1","pdf_url":"https://aacr.figshare.com/articles/journal_contribution/Supplementary_Figure_2_from_Deciphering_the_Mechanisms_of_Tumorigenesis_in_Human_Pancreatic_Ductal_Epithelial_Cells/22450671/1/files/39901749.pdf","source":null,"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"acceptedVersion","is_accepted":true,"is_published":false,"raw_source_name":"American Association for Cancer Research","raw_type":"posted-content"},"sustainable_development_goals":[{"score":0.6240000128746033,"display_name":"Good health and well-being","id":"https://metadata.un.org/sdg/3"}],"sustainable_development_goals_aurora":[],"study_designs":[],"awards":[],"funders":[],"has_content":{"grobid_xml":false,"pdf":true},"content_urls":{"pdf":"https://content.openalex.org/works/W4361908202.pdf"},"referenced_works_count":0,"referenced_works":[],"related_works":["https://openalex.org/W4361944838","https://openalex.org/W2066463229","https://openalex.org/W1973774963","https://openalex.org/W2094409040","https://openalex.org/W2054016872","https://openalex.org/W1569809284","https://openalex.org/W1974174524","https://openalex.org/W2762221523","https://openalex.org/W1991960619","https://openalex.org/W7096612865"],"abstract_inverted_index":{"PDF":[0],"file":[1],"-":[2],"169K,":[3],"Supplementary":[4],"Fig.":[5],"2.":[6],"Cell":[7],"migration":[8],"and":[9,22],"invasion":[10],"abilities":[11],"of":[12,17],"HPDE":[13],"cells":[14],"with":[15],"expression":[16],"mutant":[18],"K-ras,":[19],"Her2,":[20],"p16/p14shRNA,":[21],"Smad4shRNA.":[23]},"counts_by_year":[],"updated_date":"2026-09-29T14:09:16.559479","created_date":"2023-04-05T00:00:00"}