{"id":"https://openalex.org/W4361906381","doi":"https://doi.org/10.1158/1078-0432.22448607","title":"Supplementary File from Integrated MicroRNA Network Analyses Identify a Poor-Prognosis Subtype of Gastric Cancer Characterized by the miR-200 Family","display_name":"Supplementary File from Integrated MicroRNA Network Analyses Identify a Poor-Prognosis Subtype of Gastric Cancer Characterized by the miR-200 Family","publication_year":2023,"publication_date":"2023-03-31","ids":{"openalex":"https://openalex.org/W4361906381","doi":"https://doi.org/10.1158/1078-0432.22448607"},"language":"en","primary_location":{"id":"doi:10.1158/1078-0432.22448607","doi":"https://doi.org/10.1158/1078-0432.22448607","is_oa":true,"landing_page_url":"https://doi.org/10.1158/1078-0432.22448607","pdf_url":"https://aacr.figshare.com/articles/journal_contribution/Supplementary_File_from_Integrated_MicroRNA_Network_Analyses_Identify_a_Poor-Prognosis_Subtype_of_Gastric_Cancer_Characterized_by_the_miR-200_Family/22448607/1/files/39899658.pdf","source":null,"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"acceptedVersion","is_accepted":true,"is_published":false,"raw_source_name":"American Association for Cancer Research","raw_type":"posted-content"},"volume":null,"type":"supplementary-materials","is_traditional":false,"indexed_in":["crossref"],"open_access":{"is_oa":true,"oa_status":"gold","oa_url":"https://aacr.figshare.com/articles/journal_contribution/Supplementary_File_from_Integrated_MicroRNA_Network_Analyses_Identify_a_Poor-Prognosis_Subtype_of_Gastric_Cancer_Characterized_by_the_miR-200_Family/22448607/1/files/39899658.pdf","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5070267982","display_name":"Fengju Song","orcid":"https://orcid.org/0000-0003-1542-0828","observed_orcids":["https://orcid.org/0000-0003-1542-0828"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Fengju Song","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":null,"display_name":"Da Yang","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Da Yang","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5100462060","display_name":"Ben Liu","orcid":"https://orcid.org/0000-0001-8452-5397","observed_orcids":["https://orcid.org/0000-0001-8452-5397"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Ben Liu","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5056796466","display_name":"Yan Ping Guo","orcid":"https://orcid.org/0000-0001-5252-3960","observed_orcids":["https://orcid.org/0000-0001-5252-3960"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Yan Guo","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5100680442","display_name":"Hong Yu Zheng","orcid":"https://orcid.org/0000-0001-5802-330X","observed_orcids":["https://orcid.org/0000-0001-5802-330X"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Hong Zheng","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5100317809","display_name":"Lian Li","orcid":"https://orcid.org/0000-0003-4700-1134","observed_orcids":["https://orcid.org/0000-0003-4700-1134"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Lian Li","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":null,"display_name":"Tao Wang","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Tao Wang","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5008367011","display_name":"Jinpu Yu","orcid":"https://orcid.org/0000-0002-7016-9712","observed_orcids":["https://orcid.org/0000-0002-7016-9712","https://orcid.org/0000-0002-5982-2266"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Jinpu Yu","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5102286400","display_name":"Yanrui Zhao","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Yanrui Zhao","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5064802725","display_name":"Ruifang Niu","orcid":"https://orcid.org/0000-0002-8845-8838","observed_orcids":["https://orcid.org/0000-0002-8845-8838"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Ruifang Niu","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5105574082","display_name":"Han Liang","orcid":"https://orcid.org/0009-0006-4168-4826","observed_orcids":["https://orcid.org/0009-0006-4168-4826"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Han Liang","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":null,"display_name":"Hans Winkler","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Hans Winkler","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5100441786","display_name":"Wei Zhang","orcid":"https://orcid.org/0000-0003-3304-9161","observed_orcids":["https://orcid.org/0000-0003-3304-9161"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Wei Zhang","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5106973067","display_name":"Xishan Hao","orcid":"https://orcid.org/0000-0002-7225-0346","observed_orcids":["https://orcid.org/0000-0002-7225-0346"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Xishan Hao","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"last","author":{"id":"https://openalex.org/A5100627368","display_name":"Kexin Chen","orcid":"https://orcid.org/0000-0003-4248-7681","observed_orcids":["https://orcid.org/0000-0003-4248-7681","https://orcid.org/0009-0008-8878-9128","https://orcid.org/0009-0002-0677-9927","https://orcid.org/0009-0009-8128-8192"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Kexin Chen","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]}],"institutions":[],"countries_distinct_count":0,"institutions_distinct_count":0,"corresponding_author_ids":[],"corresponding_institution_ids":[],"apc_list":null,"apc_paid":null,"fwci":null,"has_fulltext":true,"cited_by_count":0,"citation_normalized_percentile":null,"cited_by_percentile_year":null,"biblio":{"volume":null,"issue":null,"first_page":null,"last_page":null},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10062","display_name":"MicroRNA in disease regulation","score":0.9984999895095825,"subfield":{"id":"https://openalex.org/subfields/1306","display_name":"Cancer Research"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T10062","display_name":"MicroRNA in disease regulation","score":0.9984999895095825,"subfield":{"id":"https://openalex.org/subfields/1306","display_name":"Cancer Research"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10696","display_name":"Gastric Cancer Management and Outcomes","score":0.0010000000474974513,"subfield":{"id":"https://openalex.org/subfields/2740","display_name":"Pulmonary and Respiratory Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10515","display_name":"Cancer-related molecular mechanisms research","score":9.999999747378752e-05,"subfield":{"id":"https://openalex.org/subfields/1306","display_name":"Cancer Research"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/gastric-cancer","display_name":"gastric cancer","score":1.0},{"id":"https://openalex.org/keywords/microrna","display_name":"microRNA","score":0.8199999928474426},{"id":"https://openalex.org/keywords/mir-200-family","display_name":"miR-200 family","score":0.9990000128746033},{"id":"https://openalex.org/keywords/mir-200b","display_name":"miR-200b","score":0.9309999942779541},{"id":"https://openalex.org/keywords/mir-200a","display_name":"miR-200a","score":0.9430000185966492},{"id":"https://openalex.org/keywords/mir-125b","display_name":"miR-125b","score":0.9980000257492065},{"id":"https://openalex.org/keywords/epithelial-mesenchymal-transition","display_name":"epithelial-mesenchymal transition","score":0.8849999904632568},{"id":"https://openalex.org/keywords/zeb1","display_name":"ZEB1","score":0.6290000081062317},{"id":"https://openalex.org/keywords/n-cadherin","display_name":"N-cadherin","score":0.9210000038146973},{"id":"https://openalex.org/keywords/vimentin","display_name":"vimentin","score":0.9829999804496765},{"id":"https://openalex.org/keywords/prognosis","display_name":"prognosis","score":0.7179999947547913},{"id":"https://openalex.org/keywords/patient-survival","display_name":"patient survival","score":0.7789999842643738},{"id":"https://openalex.org/keywords/mesenchymal-subtype","display_name":"mesenchymal subtype","score":0.7009999752044678},{"id":"https://openalex.org/keywords/epithelial-subtype","display_name":"epithelial subtype","score":0.8230000138282776}],"concepts":[{"id":"https://openalex.org/C145059251","wikidata":"https://www.wikidata.org/wiki/Q310899","display_name":"microRNA","level":3,"score":0.7254568338394165},{"id":"https://openalex.org/C50382708","wikidata":"https://www.wikidata.org/wiki/Q223218","display_name":"Proportional hazards model","level":2,"score":0.5825907588005066},{"id":"https://openalex.org/C143998085","wikidata":"https://www.wikidata.org/wiki/Q162555","display_name":"Oncology","level":1,"score":0.5401057600975037},{"id":"https://openalex.org/C207103383","wikidata":"https://www.wikidata.org/wiki/Q3930246","display_name":"Hazard ratio","level":3,"score":0.4867403507232666},{"id":"https://openalex.org/C2908647359","wikidata":"https://www.wikidata.org/wiki/Q2625603","display_name":"Population","level":2,"score":0.4692157506942749},{"id":"https://openalex.org/C199163554","wikidata":"https://www.wikidata.org/wiki/Q1681619","display_name":"Univariate","level":3,"score":0.46641620993614197},{"id":"https://openalex.org/C147447768","wikidata":"https://www.wikidata.org/wiki/Q411624","display_name":"Vimentin","level":3,"score":0.4642511010169983},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.4491656422615051},{"id":"https://openalex.org/C121608353","wikidata":"https://www.wikidata.org/wiki/Q12078","display_name":"Cancer","level":2,"score":0.44595104455947876},{"id":"https://openalex.org/C38180746","wikidata":"https://www.wikidata.org/wiki/Q1952580","display_name":"Multivariate analysis","level":2,"score":0.43833622336387634},{"id":"https://openalex.org/C10515644","wikidata":"https://www.wikidata.org/wiki/Q543310","display_name":"Survival analysis","level":2,"score":0.4156757891178131},{"id":"https://openalex.org/C502942594","wikidata":"https://www.wikidata.org/wiki/Q3421914","display_name":"Cancer research","level":1,"score":0.4091131389141083},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.3684602975845337},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.36178481578826904},{"id":"https://openalex.org/C161584116","wikidata":"https://www.wikidata.org/wiki/Q1952580","display_name":"Multivariate statistics","level":2,"score":0.29618945717811584},{"id":"https://openalex.org/C204232928","wikidata":"https://www.wikidata.org/wiki/Q899285","display_name":"Immunohistochemistry","level":2,"score":0.22493776679039001},{"id":"https://openalex.org/C54355233","wikidata":"https://www.wikidata.org/wiki/Q7162","display_name":"Genetics","level":1,"score":0.18605735898017883},{"id":"https://openalex.org/C104317684","wikidata":"https://www.wikidata.org/wiki/Q7187","display_name":"Gene","level":2,"score":0.09328538179397583},{"id":"https://openalex.org/C44249647","wikidata":"https://www.wikidata.org/wiki/Q208498","display_name":"Confidence interval","level":2,"score":0.0761491060256958},{"id":"https://openalex.org/C41008148","wikidata":"https://www.wikidata.org/wiki/Q21198","display_name":"Computer science","level":0,"score":0.0602584183216095},{"id":"https://openalex.org/C119857082","wikidata":"https://www.wikidata.org/wiki/Q2539","display_name":"Machine learning","level":1,"score":0.0},{"id":"https://openalex.org/C99454951","wikidata":"https://www.wikidata.org/wiki/Q932068","display_name":"Environmental health","level":1,"score":0.0}],"mesh":[],"locations_count":3,"locations":[{"id":"doi:10.1158/1078-0432.22448607","doi":"https://doi.org/10.1158/1078-0432.22448607","is_oa":true,"landing_page_url":"https://doi.org/10.1158/1078-0432.22448607","pdf_url":"https://aacr.figshare.com/articles/journal_contribution/Supplementary_File_from_Integrated_MicroRNA_Network_Analyses_Identify_a_Poor-Prognosis_Subtype_of_Gastric_Cancer_Characterized_by_the_miR-200_Family/22448607/1/files/39899658.pdf","source":null,"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"acceptedVersion","is_accepted":true,"is_published":false,"raw_source_name":"American Association for Cancer Research","raw_type":"posted-content"},{"id":"doi:10.1158/1078-0432.22448607.v1","doi":"https://doi.org/10.1158/1078-0432.22448607.v1","is_oa":true,"landing_page_url":"https://doi.org/10.1158/1078-0432.22448607.v1","pdf_url":null,"source":null,"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"acceptedVersion","is_accepted":true,"is_published":false,"raw_source_name":"American Association for Cancer Research","raw_type":"posted-content"},{"id":"pmh:oai:figshare.com:article/22448607","doi":null,"is_oa":true,"landing_page_url":"https://figshare.com/articles/journal_contribution/Supplementary_File_from_Integrated_MicroRNA_Network_Analyses_Identify_a_Poor-Prognosis_Subtype_of_Gastric_Cancer_Characterized_by_the_miR-200_Family/22448607","pdf_url":null,"source":{"id":"https://openalex.org/S4377196282","display_name":"Figshare","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I4210132348","host_organization_name":"Figshare (United Kingdom)","host_organization_lineage":["https://openalex.org/I4210132348"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"","raw_type":"Text"}],"best_oa_location":{"id":"doi:10.1158/1078-0432.22448607","doi":"https://doi.org/10.1158/1078-0432.22448607","is_oa":true,"landing_page_url":"https://doi.org/10.1158/1078-0432.22448607","pdf_url":"https://aacr.figshare.com/articles/journal_contribution/Supplementary_File_from_Integrated_MicroRNA_Network_Analyses_Identify_a_Poor-Prognosis_Subtype_of_Gastric_Cancer_Characterized_by_the_miR-200_Family/22448607/1/files/39899658.pdf","source":null,"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"acceptedVersion","is_accepted":true,"is_published":false,"raw_source_name":"American Association for Cancer Research","raw_type":"posted-content"},"sustainable_development_goals":[{"display_name":"Good health and well-being","id":"https://metadata.un.org/sdg/3","score":0.9074000120162964}],"study_designs":[],"awards":[],"funders":[],"has_content":{"pdf":true,"grobid_xml":true},"content_urls":{"pdf":"https://content.openalex.org/works/W4361906381.pdf","grobid_xml":"https://content.openalex.org/works/W4361906381.grobid-xml"},"referenced_works_count":4,"referenced_works":["https://openalex.org/W1562431437","https://openalex.org/W2026570544","https://openalex.org/W2059806955","https://openalex.org/W4294107304"],"related_works":["https://openalex.org/W4361944489","https://openalex.org/W2110170410","https://openalex.org/W1981927724","https://openalex.org/W2687127292","https://openalex.org/W2088141701","https://openalex.org/W2103562732","https://openalex.org/W3144134588","https://openalex.org/W2012511861","https://openalex.org/W2412912194","https://openalex.org/W2376098154"],"abstract_inverted_index":{"PDF":[0],"file":[1],"1705K,":[2],"Supplementary":[3],"methods,":[4],"tables,":[5],"and":[6,36,56,69,92,101,121,134,143,150],"figures":[7],"Supplemental":[8,21,32,52,73,83,94,110,124],"Table":[9,22,33,53],"1.":[10,75],"Characteristics":[11],"of":[12,25,44,62,65,77,98,114,139,148],"the":[13,19,63,99,115,137],"385":[14],"GC":[15,30,122],"cases":[16],"included":[17],"in":[18,50,71,104],"study":[20],"2.":[23,85],"Identification":[24,76],"key":[26,46,118],"microRNAs":[27,47],"associated":[28],"with":[29,48,154,165],"survival":[31,49,70,123],"3.":[34,96],"Univariate":[35,55],"multivariate":[37,57],"Cox":[38,58],"proportional":[39,59],"hazard":[40,60],"model":[41,61],"comparing":[42],"expression":[43,64,120,130,133,138],"four":[45],"GCa":[51,72],"4.":[54,112],"11":[66],"EMT":[67],"markers":[68,141],"Figure":[74,84,95,111,125],"two":[78],"gastric":[79],"cancer":[80],"microRNA":[81,119],"subtypes":[82,103],"Representative":[86],"qRT-PCR":[87],"results":[88],"for":[89,158],"miR-200a,":[90],"miR-200b,":[91],"miR-125b":[93],"Validation":[97,113],"mesenchymal":[100,140],"epithelial":[102],"an":[105],"independent":[106],"population":[107],"from":[108],"Singapore.":[109],"association":[116],"between":[117],"5.":[126],"(A)":[127],"Forced":[128],"miR-200b":[129,155],"decreased":[131,136],"ZEB1":[132],"markedly":[135],"vimentin":[142],"N-cadherin.":[144],"(B)":[145],"N-cadherin/ZEB1":[146],"staining":[147],"MGC-803":[149],"SGC-7901":[151],"cells":[152],"transfected":[153],"or":[156],"miR-Ctrl":[157],"72":[159],"hours":[160],"Cell":[161],"nuclei":[162],"were":[163],"stained":[164],"DAPI":[166]},"counts_by_year":[],"updated_date":"2026-11-04T10:54:05.112534","created_date":"2023-04-05T00:00:00"}