{"id":"https://openalex.org/W4361892471","doi":"https://doi.org/10.1158/0008-5472.22371423.v1","title":"Supplementary Figure 1A from Depletion of Peripheral Macrophages and Brain Microglia Increases Brain Tumor Titers of Oncolytic Viruses","display_name":"Supplementary Figure 1A from Depletion of Peripheral Macrophages and Brain Microglia Increases Brain Tumor Titers of Oncolytic Viruses","publication_year":2023,"publication_date":"2023-03-30","ids":{"openalex":"https://openalex.org/W4361892471","doi":"https://doi.org/10.1158/0008-5472.22371423.v1"},"language":"en","primary_location":{"id":"doi:10.1158/0008-5472.22371423.v1","doi":"https://doi.org/10.1158/0008-5472.22371423.v1","is_oa":true,"landing_page_url":"https://doi.org/10.1158/0008-5472.22371423.v1","pdf_url":null,"source":null,"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"acceptedVersion","is_accepted":true,"is_published":false,"raw_source_name":"American Association for Cancer Research","raw_type":"posted-content"},"volume":null,"type":"supplementary-materials","indexed_in":["crossref"],"open_access":{"is_oa":true,"oa_status":"gold","oa_url":"https://doi.org/10.1158/0008-5472.22371423.v1","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5091855392","display_name":"Giulia Fulci","orcid":"https://orcid.org/0000-0002-2059-9562","observed_orcids":["https://orcid.org/0000-0002-2059-9562"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Giulia Fulci","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":null,"display_name":"Nina Dmitrieva","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Nina Dmitrieva","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5057713208","display_name":"Davide Gianni","orcid":"https://orcid.org/0000-0002-6331-0677","observed_orcids":["https://orcid.org/0000-0002-6331-0677","https://orcid.org/0009-0005-6051-8201"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Davide Gianni","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5029092187","display_name":"Elisabeth J. Fontana","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Elisabeth J. Fontana","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5107658710","display_name":"Xiaogang Pan","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Xiaogang Pan","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5058891185","display_name":"Yanhui Lu","orcid":"https://orcid.org/0000-0002-6552-0248","observed_orcids":["https://orcid.org/0000-0002-6552-0248"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Yanhui Lu","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5015433569","display_name":"Claire S. Kaufman","orcid":"https://orcid.org/0000-0002-6762-2029","observed_orcids":["https://orcid.org/0000-0002-6762-2029"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Claire S. Kaufman","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5041131555","display_name":"Balveen Kaur","orcid":"https://orcid.org/0000-0001-7738-0804","observed_orcids":["https://orcid.org/0000-0001-7738-0804"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Balveen Kaur","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5008836248","display_name":"Sean Edward Lawler","orcid":"https://orcid.org/0000-0002-1633-2339","observed_orcids":["https://orcid.org/0000-0002-1633-2339"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Sean E. Lawler","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5040022220","display_name":"Robert J. Lee","orcid":"https://orcid.org/0000-0001-5826-6686","observed_orcids":["https://orcid.org/0000-0001-5826-6686"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Robert J. Lee","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5109499796","display_name":"Clay B. Marsh","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Clay B. Marsh","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5078484855","display_name":"Daniel Jay Brat","orcid":"https://orcid.org/0000-0002-0633-6563","observed_orcids":["https://orcid.org/0000-0002-0633-6563"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Daniel J. Brat","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5079003683","display_name":"Nico van Rooijen","orcid":"https://orcid.org/0000-0002-6382-1813","observed_orcids":["https://orcid.org/0000-0002-6382-1813"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Nico van Rooijen","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5027628776","display_name":"Anat Stemmer Rachamimov","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Anat Stemmer Rachamimov","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5055927065","display_name":"Fred H. Hochberg","orcid":"https://orcid.org/0000-0002-2765-8844","observed_orcids":["https://orcid.org/0000-0002-2765-8844"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Fred H. Hochberg","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5067255019","display_name":"Ralph Weissleder","orcid":"https://orcid.org/0000-0003-0828-4143","observed_orcids":["https://orcid.org/0000-0003-0828-4143"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Ralph Weissleder","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5108571976","display_name":"Robert L. Martuza","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Robert L. Martuza","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"last","author":{"id":"https://openalex.org/A5033917464","display_name":"Ennio Antonio Chiocca","orcid":"https://orcid.org/0000-0001-5183-1670","observed_orcids":["https://orcid.org/0000-0001-5183-1670"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"E. Antonio Chiocca","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]}],"institutions":[],"countries_distinct_count":0,"institutions_distinct_count":0,"corresponding_author_ids":[],"corresponding_institution_ids":[],"apc_list":null,"apc_paid":null,"fwci":null,"has_fulltext":false,"cited_by_count":0,"citation_normalized_percentile":null,"cited_by_percentile_year":null,"biblio":{"volume":null,"issue":null,"first_page":null,"last_page":null},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10613","display_name":"Virus-based gene therapy research","score":0.9833999872207642,"subfield":{"id":"https://openalex.org/subfields/1311","display_name":"Genetics"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T10613","display_name":"Virus-based gene therapy research","score":0.9833999872207642,"subfield":{"id":"https://openalex.org/subfields/1311","display_name":"Genetics"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10129","display_name":"Glioma Diagnosis and Treatment","score":0.003599999938160181,"subfield":{"id":"https://openalex.org/subfields/2716","display_name":"Genetics"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T12996","display_name":"Cancer Research and Treatments","score":0.0006000000284984708,"subfield":{"id":"https://openalex.org/subfields/1305","display_name":"Biotechnology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/peripheral-macrophages","display_name":"peripheral macrophages","score":0.9200000166893005},{"id":"https://openalex.org/keywords/brain-microglia","display_name":"brain microglia","score":0.9430000185966492},{"id":"https://openalex.org/keywords/macrophage-depletion","display_name":"macrophage depletion","score":0.9350000023841858},{"id":"https://openalex.org/keywords/oncolytic-viruses","display_name":"oncolytic viruses","score":0.8429999947547913},{"id":"https://openalex.org/keywords/glioma","display_name":"glioma","score":0.5019999742507935},{"id":"https://openalex.org/keywords/tumor-immunology","display_name":"tumor immunology","score":0.421999990940094}],"concepts":[{"id":"https://openalex.org/C2779830541","wikidata":"https://www.wikidata.org/wiki/Q1622829","display_name":"Microglia","level":3,"score":0.875359058380127},{"id":"https://openalex.org/C82210918","wikidata":"https://www.wikidata.org/wiki/Q1560099","display_name":"Oncolytic virus","level":3,"score":0.8678258061408997},{"id":"https://openalex.org/C32611913","wikidata":"https://www.wikidata.org/wiki/Q2166189","display_name":"Titer","level":3,"score":0.6718975305557251},{"id":"https://openalex.org/C46762472","wikidata":"https://www.wikidata.org/wiki/Q178648","display_name":"Peripheral","level":2,"score":0.5258015990257263},{"id":"https://openalex.org/C159047783","wikidata":"https://www.wikidata.org/wiki/Q7215","display_name":"Virology","level":1,"score":0.49711111187934875},{"id":"https://openalex.org/C2779130545","wikidata":"https://www.wikidata.org/wiki/Q233309","display_name":"Brain tumor","level":2,"score":0.49515500664711},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.4287656545639038},{"id":"https://openalex.org/C2522874641","wikidata":"https://www.wikidata.org/wiki/Q808","display_name":"Virus","level":2,"score":0.38899853825569153},{"id":"https://openalex.org/C203014093","wikidata":"https://www.wikidata.org/wiki/Q101929","display_name":"Immunology","level":1,"score":0.340205579996109},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.31488236784935},{"id":"https://openalex.org/C142724271","wikidata":"https://www.wikidata.org/wiki/Q7208","display_name":"Pathology","level":1,"score":0.19537419080734253},{"id":"https://openalex.org/C2776914184","wikidata":"https://www.wikidata.org/wiki/Q101991","display_name":"Inflammation","level":2,"score":0.09311950206756592},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.08583423495292664}],"mesh":[],"locations_count":2,"locations":[{"id":"doi:10.1158/0008-5472.22371423.v1","doi":"https://doi.org/10.1158/0008-5472.22371423.v1","is_oa":true,"landing_page_url":"https://doi.org/10.1158/0008-5472.22371423.v1","pdf_url":null,"source":null,"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"acceptedVersion","is_accepted":true,"is_published":false,"raw_source_name":"American Association for Cancer Research","raw_type":"posted-content"},{"id":"pmh:oai:figshare.com:article/22371423","doi":null,"is_oa":true,"landing_page_url":"https://figshare.com/articles/journal_contribution/Supplementary_Figure_1A_from_Depletion_of_Peripheral_Macrophages_and_Brain_Microglia_Increases_Brain_Tumor_Titers_of_Oncolytic_Viruses/22371423","pdf_url":null,"source":{"id":"https://openalex.org/S4377196282","display_name":"Figshare","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I4210132348","host_organization_name":"Figshare (United Kingdom)","host_organization_lineage":["https://openalex.org/I4210132348"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"","raw_type":"Text"}],"best_oa_location":{"id":"doi:10.1158/0008-5472.22371423.v1","doi":"https://doi.org/10.1158/0008-5472.22371423.v1","is_oa":true,"landing_page_url":"https://doi.org/10.1158/0008-5472.22371423.v1","pdf_url":null,"source":null,"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"acceptedVersion","is_accepted":true,"is_published":false,"raw_source_name":"American Association for Cancer Research","raw_type":"posted-content"},"sustainable_development_goals":[{"score":0.9537000060081482,"id":"https://metadata.un.org/sdg/3","display_name":"Good health and well-being"}],"sustainable_development_goals_aurora":[],"study_designs":[],"awards":[],"funders":[],"has_content":{"grobid_xml":false,"pdf":false},"content_urls":null,"referenced_works_count":0,"referenced_works":[],"related_works":["https://openalex.org/W2206996832","https://openalex.org/W2113309441","https://openalex.org/W2372806257","https://openalex.org/W4293088736","https://openalex.org/W1507667107","https://openalex.org/W1551219790","https://openalex.org/W2981223870","https://openalex.org/W4386623818","https://openalex.org/W2388430340","https://openalex.org/W2070108306"],"abstract_inverted_index":{"Supplementary":[0],"Figure":[1],"1A":[2],"from":[3],"Depletion":[4],"of":[5,15],"Peripheral":[6],"Macrophages":[7],"and":[8],"Brain":[9,12],"Microglia":[10],"Increases":[11],"Tumor":[13],"Titers":[14],"Oncolytic":[16],"Viruses":[17]},"counts_by_year":[],"updated_date":"2026-10-14T16:39:01.820549","created_date":"2025-10-10T00:00:00"}