{"id":"https://openalex.org/W4361892404","doi":"https://doi.org/10.1158/0008-5472.22371126.v1","title":"Supplementary Figure Legends 1-2 from The Nucleolin Targeting Aptamer AS1411 Destabilizes Bcl-2 Messenger RNA in Human Breast Cancer Cells","display_name":"Supplementary Figure Legends 1-2 from The Nucleolin Targeting Aptamer AS1411 Destabilizes Bcl-2 Messenger RNA in Human Breast Cancer Cells","publication_year":2023,"publication_date":"2023-03-30","ids":{"openalex":"https://openalex.org/W4361892404","doi":"https://doi.org/10.1158/0008-5472.22371126.v1"},"language":"en","primary_location":{"id":"doi:10.1158/0008-5472.22371126.v1","doi":"https://doi.org/10.1158/0008-5472.22371126.v1","is_oa":true,"landing_page_url":"https://doi.org/10.1158/0008-5472.22371126.v1","pdf_url":"https://aacr.figshare.com/articles/journal_contribution/Supplementary_Figure_Legends_1-2_from_The_Nucleolin_Targeting_Aptamer_AS1411_Destabilizes_i_Bcl-2_i_Messenger_RNA_in_Human_Breast_Cancer_Cells/22371126/1/files/39816219.pdf","source":null,"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"acceptedVersion","is_accepted":true,"is_published":false,"raw_source_name":"American Association for Cancer Research","raw_type":"posted-content"},"volume":null,"type":"supplementary-materials","indexed_in":["crossref"],"open_access":{"is_oa":true,"oa_status":"gold","oa_url":"https://aacr.figshare.com/articles/journal_contribution/Supplementary_Figure_Legends_1-2_from_The_Nucleolin_Targeting_Aptamer_AS1411_Destabilizes_i_Bcl-2_i_Messenger_RNA_in_Human_Breast_Cancer_Cells/22371126/1/files/39816219.pdf","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5040645328","display_name":"Sridharan Soundararajan","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Sridharan Soundararajan","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5100367118","display_name":"Weiwei Chen","orcid":"https://orcid.org/0000-0001-7681-3962","observed_orcids":["https://orcid.org/0000-0001-7681-3962","https://orcid.org/0000-0002-9682-0315"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Weiwei Chen","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5110072617","display_name":"Eleanor K. Spicer","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Eleanor K. Spicer","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5023669521","display_name":"Nigel S. Courtenay-Luck","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Nigel Courtenay-Luck","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"last","author":{"id":"https://openalex.org/A5021780080","display_name":"Daniel Fernandes","orcid":"https://orcid.org/0000-0002-8935-4176","observed_orcids":["https://orcid.org/0000-0002-8935-4176"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Daniel J. Fernandes","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]}],"institutions":[],"countries_distinct_count":0,"institutions_distinct_count":0,"corresponding_author_ids":[],"corresponding_institution_ids":[],"apc_list":null,"apc_paid":null,"fwci":null,"has_fulltext":false,"cited_by_count":0,"citation_normalized_percentile":null,"cited_by_percentile_year":null,"biblio":{"volume":null,"issue":null,"first_page":null,"last_page":null},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10725","display_name":"RNA Interference and Gene Delivery","score":0.4496999979019165,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T10725","display_name":"RNA Interference and Gene Delivery","score":0.4496999979019165,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10604","display_name":"RNA Research and Splicing","score":0.26460000872612,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10294","display_name":"Cell death mechanisms and regulation","score":0.11020000278949738,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/as1411","display_name":"AS1411","score":0.9589999914169312},{"id":"https://openalex.org/keywords/nucleolin","display_name":"nucleolin","score":0.8130000233650208},{"id":"https://openalex.org/keywords/aptamers","display_name":"aptamers","score":0.7620000243186951},{"id":"https://openalex.org/keywords/bcl-2","display_name":"Bcl-2","score":0.9020000100135803},{"id":"https://openalex.org/keywords/mrna-destabilization","display_name":"mRNA destabilization","score":0.9160000085830688},{"id":"https://openalex.org/keywords/breast-cancer","display_name":"breast cancer","score":0.6620000004768372},{"id":"https://openalex.org/keywords/rna-stability","display_name":"RNA stability","score":0.35600000619888306}],"concepts":[{"id":"https://openalex.org/C2776525860","wikidata":"https://www.wikidata.org/wiki/Q18029887","display_name":"Nucleolin","level":4,"score":0.9861045479774475},{"id":"https://openalex.org/C128972844","wikidata":"https://www.wikidata.org/wiki/Q418722","display_name":"Aptamer","level":2,"score":0.7841283082962036},{"id":"https://openalex.org/C105580179","wikidata":"https://www.wikidata.org/wiki/Q188928","display_name":"Messenger RNA","level":3,"score":0.7175307869911194},{"id":"https://openalex.org/C67705224","wikidata":"https://www.wikidata.org/wiki/Q11053","display_name":"RNA","level":3,"score":0.6320199966430664},{"id":"https://openalex.org/C2994423619","wikidata":"https://www.wikidata.org/wiki/Q9103","display_name":"Human breast","level":4,"score":0.593418300151825},{"id":"https://openalex.org/C502942594","wikidata":"https://www.wikidata.org/wiki/Q3421914","display_name":"Cancer research","level":1,"score":0.44139716029167175},{"id":"https://openalex.org/C530470458","wikidata":"https://www.wikidata.org/wiki/Q128581","display_name":"Breast cancer","level":3,"score":0.42364105582237244},{"id":"https://openalex.org/C153911025","wikidata":"https://www.wikidata.org/wiki/Q7202","display_name":"Molecular biology","level":1,"score":0.42251116037368774},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.3994778096675873},{"id":"https://openalex.org/C121608353","wikidata":"https://www.wikidata.org/wiki/Q12078","display_name":"Cancer","level":2,"score":0.39089423418045044},{"id":"https://openalex.org/C95444343","wikidata":"https://www.wikidata.org/wiki/Q7141","display_name":"Cell biology","level":1,"score":0.35609978437423706},{"id":"https://openalex.org/C185592680","wikidata":"https://www.wikidata.org/wiki/Q2329","display_name":"Chemistry","level":0,"score":0.34162217378616333},{"id":"https://openalex.org/C54355233","wikidata":"https://www.wikidata.org/wiki/Q7162","display_name":"Genetics","level":1,"score":0.2072540521621704},{"id":"https://openalex.org/C104317684","wikidata":"https://www.wikidata.org/wiki/Q7187","display_name":"Gene","level":2,"score":0.18256878852844238},{"id":"https://openalex.org/C183873130","wikidata":"https://www.wikidata.org/wiki/Q30869","display_name":"Nucleolus","level":3,"score":0.06458646059036255},{"id":"https://openalex.org/C190062978","wikidata":"https://www.wikidata.org/wiki/Q79899","display_name":"Cytoplasm","level":2,"score":0.0}],"mesh":[],"locations_count":2,"locations":[{"id":"doi:10.1158/0008-5472.22371126.v1","doi":"https://doi.org/10.1158/0008-5472.22371126.v1","is_oa":true,"landing_page_url":"https://doi.org/10.1158/0008-5472.22371126.v1","pdf_url":"https://aacr.figshare.com/articles/journal_contribution/Supplementary_Figure_Legends_1-2_from_The_Nucleolin_Targeting_Aptamer_AS1411_Destabilizes_i_Bcl-2_i_Messenger_RNA_in_Human_Breast_Cancer_Cells/22371126/1/files/39816219.pdf","source":null,"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"acceptedVersion","is_accepted":true,"is_published":false,"raw_source_name":"American Association for Cancer Research","raw_type":"posted-content"},{"id":"pmh:oai:figshare.com:article/22371126","doi":null,"is_oa":true,"landing_page_url":"https://figshare.com/articles/journal_contribution/Supplementary_Figure_Legends_1-2_from_The_Nucleolin_Targeting_Aptamer_AS1411_Destabilizes_i_Bcl-2_i_Messenger_RNA_in_Human_Breast_Cancer_Cells/22371126","pdf_url":null,"source":{"id":"https://openalex.org/S4377196282","display_name":"Figshare","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I4210132348","host_organization_name":"Figshare (United Kingdom)","host_organization_lineage":["https://openalex.org/I4210132348"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"","raw_type":"Text"}],"best_oa_location":{"id":"doi:10.1158/0008-5472.22371126.v1","doi":"https://doi.org/10.1158/0008-5472.22371126.v1","is_oa":true,"landing_page_url":"https://doi.org/10.1158/0008-5472.22371126.v1","pdf_url":"https://aacr.figshare.com/articles/journal_contribution/Supplementary_Figure_Legends_1-2_from_The_Nucleolin_Targeting_Aptamer_AS1411_Destabilizes_i_Bcl-2_i_Messenger_RNA_in_Human_Breast_Cancer_Cells/22371126/1/files/39816219.pdf","source":null,"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"acceptedVersion","is_accepted":true,"is_published":false,"raw_source_name":"American Association for Cancer Research","raw_type":"posted-content"},"sustainable_development_goals":[{"score":0.4043000042438507,"id":"https://metadata.un.org/sdg/3","display_name":"Good health and well-being"}],"sustainable_development_goals_aurora":[{"score":0.46000000834465027,"id":"https://metadata.un.org/sdg/3","display_name":"Good health and well-being"}],"study_designs":[],"awards":[],"funders":[],"has_content":{"grobid_xml":true,"pdf":true},"content_urls":{"pdf":"https://content.openalex.org/works/W4361892404.pdf","grobid_xml":"https://content.openalex.org/works/W4361892404.grobid-xml"},"referenced_works_count":0,"referenced_works":[],"related_works":["https://openalex.org/W2044824066","https://openalex.org/W4361822911","https://openalex.org/W2902933262","https://openalex.org/W2986752244","https://openalex.org/W2900043549","https://openalex.org/W2177067006","https://openalex.org/W7098696657","https://openalex.org/W7096198375","https://openalex.org/W4386942017","https://openalex.org/W7127572900"],"abstract_inverted_index":{"Supplementary":[0],"Figure":[1],"Legends":[2],"1-2":[3],"from":[4],"The":[5],"Nucleolin":[6],"Targeting":[7],"Aptamer":[8],"AS1411":[9],"Destabilizes":[10],"Bcl-2":[11],"Messenger":[12],"RNA":[13],"in":[14],"Human":[15],"Breast":[16],"Cancer":[17],"Cells":[18]},"counts_by_year":[],"updated_date":"2026-09-24T07:57:37.273135","created_date":"2023-04-05T00:00:00"}