{"id":"https://openalex.org/W4361889005","doi":"https://doi.org/10.1158/1078-0432.22478166","title":"Supplementary material from Predominance of Central Memory T Cells with High T-Cell Receptor Repertoire Diversity is Associated with Response to PD-1/PD-L1 Inhibition in Merkel Cell Carcinoma","display_name":"Supplementary material from Predominance of Central Memory T Cells with High T-Cell Receptor Repertoire Diversity is Associated with Response to PD-1/PD-L1 Inhibition in Merkel Cell Carcinoma","publication_year":2023,"publication_date":"2023-03-31","ids":{"openalex":"https://openalex.org/W4361889005","doi":"https://doi.org/10.1158/1078-0432.22478166"},"language":"en","primary_location":{"id":"doi:10.1158/1078-0432.22478166","doi":"https://doi.org/10.1158/1078-0432.22478166","is_oa":true,"landing_page_url":"https://doi.org/10.1158/1078-0432.22478166","pdf_url":null,"source":null,"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"acceptedVersion","is_accepted":true,"is_published":false,"raw_source_name":"American Association for Cancer Research","raw_type":"posted-content"},"volume":null,"type":"supplementary-materials","indexed_in":["crossref"],"open_access":{"is_oa":true,"oa_status":"gold","oa_url":"https://doi.org/10.1158/1078-0432.22478166","any_repository_has_fulltext":null},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5003322799","display_name":"Ivelina Spassova","orcid":"https://orcid.org/0000-0003-4663-7966","observed_orcids":["https://orcid.org/0000-0003-4663-7966"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Ivelina Spassova","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5057381405","display_name":"Selma Ugurel","orcid":"https://orcid.org/0000-0002-9384-6704","observed_orcids":["https://orcid.org/0000-0002-9384-6704"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Selma Ugurel","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5004458225","display_name":"Patrick Andres Maximilian Terheyden","orcid":"https://orcid.org/0000-0002-5894-1677","observed_orcids":["https://orcid.org/0000-0002-5894-1677"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Patrick Terheyden","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5049279715","display_name":"Antje Sucker","orcid":"https://orcid.org/0000-0002-2753-9626","observed_orcids":["https://orcid.org/0000-0002-2753-9626"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Antje Sucker","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5067776208","display_name":"Jessica C. Hassel","orcid":"https://orcid.org/0000-0001-7575-6230","observed_orcids":["https://orcid.org/0000-0001-7575-6230"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Jessica C. Hassel","raw_affiliation_strings":[],"raw_orcid":"https://orcid.org/0000-0001-7575-6230","affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5048230594","display_name":"Cathrin Ritter","orcid":"https://orcid.org/0000-0001-7027-8292","observed_orcids":["https://orcid.org/0000-0001-7027-8292"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Cathrin Ritter","raw_affiliation_strings":[],"raw_orcid":"https://orcid.org/0000-0001-7027-8292","affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5061799770","display_name":"Linda Kubat","orcid":"https://orcid.org/0000-0001-7046-2663","observed_orcids":["https://orcid.org/0000-0001-7046-2663"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Linda Kubat","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5085990218","display_name":"Daniel Habermann","orcid":"https://orcid.org/0000-0003-3685-7287","observed_orcids":["https://orcid.org/0000-0003-3685-7287"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Daniel Habermann","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5055218640","display_name":"Farnoush Farahpour","orcid":"https://orcid.org/0000-0002-4510-8483","observed_orcids":["https://orcid.org/0000-0002-4510-8483"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Farnoush Farahpour","raw_affiliation_strings":[],"raw_orcid":"https://orcid.org/0000-0002-4510-8483","affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5069211175","display_name":"Mohammadkarim Saeedghalati","orcid":"https://orcid.org/0000-0003-3387-6263","observed_orcids":["https://orcid.org/0000-0003-3387-6263"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Mohammadkarim Saeedghalati","raw_affiliation_strings":[],"raw_orcid":"https://orcid.org/0000-0003-3387-6263","affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5074402008","display_name":"Lukas Peiffer","orcid":"https://orcid.org/0000-0003-3729-2249","observed_orcids":["https://orcid.org/0000-0003-3729-2249"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Lukas Peiffer","raw_affiliation_strings":[],"raw_orcid":"https://orcid.org/0000-0003-3729-2249","affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5100404594","display_name":"Rajiv Kumar","orcid":"https://orcid.org/0000-0002-6093-0395","observed_orcids":["https://orcid.org/0000-0002-6093-0395"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Rajiv Kumar","raw_affiliation_strings":[],"raw_orcid":"https://orcid.org/0000-0002-6093-0395","affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5005332655","display_name":"David Schrama","orcid":"https://orcid.org/0000-0002-6931-8194","observed_orcids":["https://orcid.org/0000-0002-6931-8194"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"David Schrama","raw_affiliation_strings":[],"raw_orcid":"https://orcid.org/0000-0002-6931-8194","affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5074555350","display_name":"Daniel E. Hoffmann","orcid":"https://orcid.org/0000-0003-2973-7869","observed_orcids":["https://orcid.org/0000-0003-2973-7869"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Daniel Hoffmann","raw_affiliation_strings":[],"raw_orcid":"https://orcid.org/0000-0003-2973-7869","affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5034365278","display_name":"Dirk Schadendorf","orcid":"https://orcid.org/0000-0003-3524-7858","observed_orcids":["https://orcid.org/0000-0003-3524-7858"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Dirk Schadendorf","raw_affiliation_strings":[],"raw_orcid":"https://orcid.org/0000-0003-3524-7858","affiliations":[]},{"author_position":"last","author":{"id":"https://openalex.org/A5067045121","display_name":"J\u00fcrgen Christian Becker","orcid":"https://orcid.org/0000-0001-9183-653X","observed_orcids":["https://orcid.org/0000-0001-9183-653X"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"J\u00fcrgen C. Becker","raw_affiliation_strings":[],"raw_orcid":"https://orcid.org/0000-0001-9183-653X","affiliations":[]}],"institutions":[],"countries_distinct_count":0,"institutions_distinct_count":0,"corresponding_author_ids":[],"corresponding_institution_ids":[],"apc_list":null,"apc_paid":null,"fwci":null,"has_fulltext":false,"cited_by_count":0,"citation_normalized_percentile":null,"cited_by_percentile_year":null,"biblio":{"volume":null,"issue":null,"first_page":null,"last_page":null},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T11827","display_name":"Polyomavirus and related diseases","score":0.8041999936103821,"subfield":{"id":"https://openalex.org/subfields/2730","display_name":"Oncology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T11827","display_name":"Polyomavirus and related diseases","score":0.8041999936103821,"subfield":{"id":"https://openalex.org/subfields/2730","display_name":"Oncology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10158","display_name":"Cancer Immunotherapy and Biomarkers","score":0.15539999306201935,"subfield":{"id":"https://openalex.org/subfields/2730","display_name":"Oncology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10031","display_name":"T-cell and B-cell Immunology","score":0.01489999983459711,"subfield":{"id":"https://openalex.org/subfields/2403","display_name":"Immunology"},"field":{"id":"https://openalex.org/fields/24","display_name":"Immunology and Microbiology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/central-memory-t-cells","display_name":"central memory T cells","score":0.8840000033378601},{"id":"https://openalex.org/keywords/t-cell-receptor-diversity","display_name":"T cell receptor diversity","score":0.9729999899864197},{"id":"https://openalex.org/keywords/pd-1-pd-l1-blockade","display_name":"PD-1/PD-L1 blockade","score":0.9490000009536743},{"id":"https://openalex.org/keywords/merkel-cell-carcinoma","display_name":"Merkel cell carcinoma","score":0.8360000252723694},{"id":"https://openalex.org/keywords/immune-checkpoint-inhibitors","display_name":"immune checkpoint inhibitors","score":0.6480000019073486},{"id":"https://openalex.org/keywords/treatment-response","display_name":"treatment response","score":0.4959999918937683},{"id":"https://openalex.org/keywords/bayesian-analysis","display_name":"Bayesian analysis","score":0.7419999837875366}],"concepts":[{"id":"https://openalex.org/C2778473898","wikidata":"https://www.wikidata.org/wiki/Q2145110","display_name":"Repertoire","level":2,"score":0.7080643773078918},{"id":"https://openalex.org/C2778342957","wikidata":"https://www.wikidata.org/wiki/Q1711744","display_name":"Merkel cell carcinoma","level":3,"score":0.5745530724525452},{"id":"https://openalex.org/C502942594","wikidata":"https://www.wikidata.org/wiki/Q3421914","display_name":"Cancer research","level":1,"score":0.5001797676086426},{"id":"https://openalex.org/C2781053074","wikidata":"https://www.wikidata.org/wiki/Q21100639","display_name":"PD-L1","level":4,"score":0.44537100195884705},{"id":"https://openalex.org/C2781316041","wikidata":"https://www.wikidata.org/wiki/Q1230584","display_name":"Diversity (politics)","level":2,"score":0.4252168536186218},{"id":"https://openalex.org/C170493617","wikidata":"https://www.wikidata.org/wiki/Q208467","display_name":"Receptor","level":2,"score":0.42255187034606934},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.39713627099990845},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.26973116397857666},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.25574246048927307},{"id":"https://openalex.org/C203014093","wikidata":"https://www.wikidata.org/wiki/Q101929","display_name":"Immunology","level":1,"score":0.2371324598789215},{"id":"https://openalex.org/C2777546739","wikidata":"https://www.wikidata.org/wiki/Q33525","display_name":"Carcinoma","level":2,"score":0.21064722537994385},{"id":"https://openalex.org/C8891405","wikidata":"https://www.wikidata.org/wiki/Q1059","display_name":"Immune system","level":2,"score":0.1860419511795044},{"id":"https://openalex.org/C2777701055","wikidata":"https://www.wikidata.org/wiki/Q1427096","display_name":"Immunotherapy","level":3,"score":0.15395283699035645},{"id":"https://openalex.org/C144024400","wikidata":"https://www.wikidata.org/wiki/Q21201","display_name":"Sociology","level":0,"score":0.08405062556266785},{"id":"https://openalex.org/C142362112","wikidata":"https://www.wikidata.org/wiki/Q735","display_name":"Art","level":0,"score":0.08045554161071777},{"id":"https://openalex.org/C19165224","wikidata":"https://www.wikidata.org/wiki/Q23404","display_name":"Anthropology","level":1,"score":0.0},{"id":"https://openalex.org/C124952713","wikidata":"https://www.wikidata.org/wiki/Q8242","display_name":"Literature","level":1,"score":0.0}],"mesh":[],"locations_count":1,"locations":[{"id":"doi:10.1158/1078-0432.22478166","doi":"https://doi.org/10.1158/1078-0432.22478166","is_oa":true,"landing_page_url":"https://doi.org/10.1158/1078-0432.22478166","pdf_url":null,"source":null,"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"acceptedVersion","is_accepted":true,"is_published":false,"raw_source_name":"American Association for Cancer Research","raw_type":"posted-content"}],"best_oa_location":{"id":"doi:10.1158/1078-0432.22478166","doi":"https://doi.org/10.1158/1078-0432.22478166","is_oa":true,"landing_page_url":"https://doi.org/10.1158/1078-0432.22478166","pdf_url":null,"source":null,"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"acceptedVersion","is_accepted":true,"is_published":false,"raw_source_name":"American Association for Cancer Research","raw_type":"posted-content"},"sustainable_development_goals":[{"display_name":"Good health and well-being","id":"https://metadata.un.org/sdg/3","score":0.9391000270843506}],"study_designs":[],"awards":[],"funders":[],"has_content":{"grobid_xml":false,"pdf":false},"content_urls":null,"referenced_works_count":0,"referenced_works":[],"related_works":["https://openalex.org/W4361889058","https://openalex.org/W4361888912","https://openalex.org/W4361889024","https://openalex.org/W4361961950","https://openalex.org/W4361962287","https://openalex.org/W4361889056","https://openalex.org/W4361938150","https://openalex.org/W2998737960","https://openalex.org/W4361959631","https://openalex.org/W3036112193"],"abstract_inverted_index":{"Supplementary":[0],"material":[1],"(Bayes":[2],"Analysis)":[3]},"counts_by_year":[],"updated_date":"2026-10-14T16:39:01.820549","created_date":"2023-04-05T00:00:00"}