{"id":"https://openalex.org/W4361880293","doi":"https://doi.org/10.1158/0008-5472.22421693","title":"Supplementary Tables from HER2 Overexpression Triggers an IL1\u03b1 Proinflammatory Circuit to Drive Tumorigenesis and Promote Chemotherapy Resistance","display_name":"Supplementary Tables from HER2 Overexpression Triggers an IL1\u03b1 Proinflammatory Circuit to Drive Tumorigenesis and Promote Chemotherapy Resistance","publication_year":2023,"publication_date":"2023-03-31","ids":{"openalex":"https://openalex.org/W4361880293","doi":"https://doi.org/10.1158/0008-5472.22421693"},"language":"en","primary_location":{"id":"doi:10.1158/0008-5472.22421693","doi":"https://doi.org/10.1158/0008-5472.22421693","is_oa":true,"landing_page_url":"http://dx.doi.org/10.1158/0008-5472.22421693","pdf_url":null,"source":null,"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"acceptedVersion","is_accepted":true,"is_published":false,"raw_source_name":"American Association for Cancer Research","raw_type":"posted-content"},"volume":null,"type":"supplementary-materials","indexed_in":["crossref"],"open_access":{"is_oa":true,"oa_status":"gold","oa_url":"http://dx.doi.org/10.1158/0008-5472.22421693","any_repository_has_fulltext":null},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5111656492","display_name":"Shou Liu","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Shou Liu","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5079522224","display_name":"Ji Shin Lee","orcid":"https://orcid.org/0000-0003-4634-2228","observed_orcids":["https://orcid.org/0000-0003-4634-2228"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Ji Shin Lee","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5069829773","display_name":"Chunfa Jie","orcid":"https://orcid.org/0000-0003-4838-5168","observed_orcids":["https://orcid.org/0000-0003-4838-5168"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Chunfa Jie","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5041704574","display_name":"Min Ho Park","orcid":"https://orcid.org/0000-0003-1504-3815","observed_orcids":["https://orcid.org/0000-0003-1504-3815"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Min Ho Park","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5074919264","display_name":"Yoichiro Iwakura","orcid":"https://orcid.org/0000-0002-9934-5775","observed_orcids":["https://orcid.org/0000-0002-9934-5775"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Yoichiro Iwakura","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5017699573","display_name":"Yogin K. Patel","orcid":"https://orcid.org/0000-0002-1951-009X","observed_orcids":["https://orcid.org/0000-0002-1951-009X"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Yogin Patel","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5029164728","display_name":"Mithil K. Soni","orcid":"https://orcid.org/0000-0001-9387-0221","observed_orcids":["https://orcid.org/0000-0001-9387-0221"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Mithil Soni","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5017253679","display_name":"David Reisman","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"David Reisman","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"last","author":{"id":"https://openalex.org/A5114375978","display_name":"Hexin Chen","orcid":"https://orcid.org/0000-0001-9300-0859","observed_orcids":["https://orcid.org/0000-0001-9300-0859"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Hexin Chen","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]}],"institutions":[],"countries_distinct_count":0,"institutions_distinct_count":0,"corresponding_author_ids":[],"corresponding_institution_ids":[],"apc_list":null,"apc_paid":null,"fwci":null,"has_fulltext":false,"cited_by_count":0,"citation_normalized_percentile":null,"cited_by_percentile_year":null,"biblio":{"volume":null,"issue":null,"first_page":null,"last_page":null},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10755","display_name":"HER2/EGFR in Cancer Research","score":0.9883000254631042,"subfield":{"id":"https://openalex.org/subfields/2730","display_name":"Oncology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T10755","display_name":"HER2/EGFR in Cancer Research","score":0.9883000254631042,"subfield":{"id":"https://openalex.org/subfields/2730","display_name":"Oncology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10336","display_name":"Cancer Cells and Metastasis","score":0.003599999938160181,"subfield":{"id":"https://openalex.org/subfields/2730","display_name":"Oncology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10183","display_name":"Breast Cancer Treatment Studies","score":0.0010999999940395355,"subfield":{"id":"https://openalex.org/subfields/1306","display_name":"Cancer Research"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/her2-overexpression","display_name":"HER2 overexpression","score":1.0},{"id":"https://openalex.org/keywords/interleukin-1-alpha","display_name":"interleukin-1 alpha","score":0.8230000138282776},{"id":"https://openalex.org/keywords/carcinogenesis","display_name":"carcinogenesis","score":0.9359999895095825},{"id":"https://openalex.org/keywords/chemoresistance","display_name":"chemoresistance","score":0.9959999918937683},{"id":"https://openalex.org/keywords/breast-cancer","display_name":"breast cancer","score":0.8790000081062317},{"id":"https://openalex.org/keywords/cancer-stem-cells","display_name":"cancer stem cells","score":0.9660000205039978},{"id":"https://openalex.org/keywords/interleukin-6","display_name":"interleukin-6","score":0.8960000276565552},{"id":"https://openalex.org/keywords/tumor-microenvironment","display_name":"tumor microenvironment","score":0.41999998688697815}],"concepts":[{"id":"https://openalex.org/C555283112","wikidata":"https://www.wikidata.org/wiki/Q1637543","display_name":"Carcinogenesis","level":3,"score":0.660480797290802},{"id":"https://openalex.org/C164027704","wikidata":"https://www.wikidata.org/wiki/Q3491837","display_name":"Proinflammatory cytokine","level":3,"score":0.6438180208206177},{"id":"https://openalex.org/C161584116","wikidata":"https://www.wikidata.org/wiki/Q1952580","display_name":"Multivariate statistics","level":2,"score":0.5805545449256897},{"id":"https://openalex.org/C502942594","wikidata":"https://www.wikidata.org/wiki/Q3421914","display_name":"Cancer research","level":1,"score":0.4809550344944},{"id":"https://openalex.org/C143998085","wikidata":"https://www.wikidata.org/wiki/Q162555","display_name":"Oncology","level":1,"score":0.4471985995769501},{"id":"https://openalex.org/C530470458","wikidata":"https://www.wikidata.org/wiki/Q128581","display_name":"Breast cancer","level":3,"score":0.42660921812057495},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.4105183184146881},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.3794713616371155},{"id":"https://openalex.org/C121608353","wikidata":"https://www.wikidata.org/wiki/Q12078","display_name":"Cancer","level":2,"score":0.33948731422424316},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.30454158782958984},{"id":"https://openalex.org/C105795698","wikidata":"https://www.wikidata.org/wiki/Q12483","display_name":"Statistics","level":1,"score":0.1111307144165039},{"id":"https://openalex.org/C33923547","wikidata":"https://www.wikidata.org/wiki/Q395","display_name":"Mathematics","level":0,"score":0.10847654938697815},{"id":"https://openalex.org/C2776914184","wikidata":"https://www.wikidata.org/wiki/Q101991","display_name":"Inflammation","level":2,"score":0.069406658411026}],"mesh":[],"locations_count":1,"locations":[{"id":"doi:10.1158/0008-5472.22421693","doi":"https://doi.org/10.1158/0008-5472.22421693","is_oa":true,"landing_page_url":"http://dx.doi.org/10.1158/0008-5472.22421693","pdf_url":null,"source":null,"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"acceptedVersion","is_accepted":true,"is_published":false,"raw_source_name":"American Association for Cancer Research","raw_type":"posted-content"}],"best_oa_location":{"id":"doi:10.1158/0008-5472.22421693","doi":"https://doi.org/10.1158/0008-5472.22421693","is_oa":true,"landing_page_url":"http://dx.doi.org/10.1158/0008-5472.22421693","pdf_url":null,"source":null,"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"acceptedVersion","is_accepted":true,"is_published":false,"raw_source_name":"American Association for Cancer Research","raw_type":"posted-content"},"sustainable_development_goals":[{"score":0.9789000153541565,"id":"https://metadata.un.org/sdg/3","display_name":"Good health and well-being"}],"study_designs":[],"awards":[],"funders":[],"has_content":{"grobid_xml":false,"pdf":false},"content_urls":null,"referenced_works_count":0,"referenced_works":[],"related_works":["https://openalex.org/W4361824949","https://openalex.org/W2797521429","https://openalex.org/W2741195018","https://openalex.org/W4392724474","https://openalex.org/W2103315206","https://openalex.org/W2884462708","https://openalex.org/W2115585914","https://openalex.org/W2021224960","https://openalex.org/W4361824321","https://openalex.org/W2326486936"],"abstract_inverted_index":{"Supplementary":[0,3],"Tables":[1,4],"-":[2],"S1,":[5],"S3":[6,20],"and":[7,31],"S4.":[8],"S1":[9],"shows":[10,21],"frequency":[11],"of":[12,16],"CSCs":[13],"after":[14],"transplantation":[15],"the":[17],"indicated":[18],"cells.":[19],"multivariate":[22],"Cox":[23],"regression":[24],"data.":[25],"S4":[26],"Positive":[27],"correlation":[28],"between":[29],"IL-1\u03b1":[30],"HER2":[32],"or":[33],"IL6":[34],"expression":[35],"in":[36],"breast":[37],"cancer":[38],"tissues.":[39]},"counts_by_year":[],"updated_date":"2026-10-09T09:14:12.587421","created_date":"2023-04-05T00:00:00"}