{"id":"https://openalex.org/W4361850962","doi":"https://doi.org/10.1158/0008-5472.22411056","title":"Supplementary Tables from A KDM5 Inhibitor Increases Global H3K4 Trimethylation Occupancy and Enhances the Biological Efficacy of 5-Aza-2\u2032-Deoxycytidine","display_name":"Supplementary Tables from A KDM5 Inhibitor Increases Global H3K4 Trimethylation Occupancy and Enhances the Biological Efficacy of 5-Aza-2\u2032-Deoxycytidine","publication_year":2023,"publication_date":"2023-03-31","ids":{"openalex":"https://openalex.org/W4361850962","doi":"https://doi.org/10.1158/0008-5472.22411056"},"language":"en","primary_location":{"id":"doi:10.1158/0008-5472.22411056","doi":"https://doi.org/10.1158/0008-5472.22411056","is_oa":true,"landing_page_url":"https://doi.org/10.1158/0008-5472.22411056","pdf_url":"https://aacr.figshare.com/articles/journal_contribution/Supplementary_Tables_from_A_KDM5_Inhibitor_Increases_Global_H3K4_Trimethylation_Occupancy_and_Enhances_the_Biological_Efficacy_of_5-Aza-2_-Deoxycytidine/22411056/1/files/39856974.pdf","source":null,"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"acceptedVersion","is_accepted":true,"is_published":false,"raw_source_name":"American Association for Cancer Research","raw_type":"posted-content"},"volume":null,"type":"supplementary-materials","indexed_in":["crossref"],"open_access":{"is_oa":true,"oa_status":"gold","oa_url":"https://aacr.figshare.com/articles/journal_contribution/Supplementary_Tables_from_A_KDM5_Inhibitor_Increases_Global_H3K4_Trimethylation_Occupancy_and_Enhances_the_Biological_Efficacy_of_5-Aza-2_-Deoxycytidine/22411056/1/files/39856974.pdf","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5111794353","display_name":"Benjamin R. Leadem","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Benjamin R. Leadem","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5010395260","display_name":"Ioannis Kagiampakis","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Ioannis Kagiampakis","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5109032991","display_name":"Catherine Wilson","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Catherine Wilson","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5044914775","display_name":"Tommy K. Cheung","orcid":"https://orcid.org/0009-0008-1053-9831","observed_orcids":["https://orcid.org/0009-0008-1053-9831"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Tommy K. Cheung","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5110899571","display_name":"David Arnott","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"David Arnott","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5013707401","display_name":"Patrick Trojer","orcid":"https://orcid.org/0000-0001-9969-9154","observed_orcids":["https://orcid.org/0000-0001-9969-9154"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Patrick Trojer","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5113594384","display_name":"Marie Classon","orcid":"https://orcid.org/0009-0007-3305-1890","observed_orcids":["https://orcid.org/0009-0007-3305-1890"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Marie Classon","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5034057788","display_name":"Hariharan Easwaran","orcid":"https://orcid.org/0000-0002-5517-2972","observed_orcids":["https://orcid.org/0000-0002-5517-2972"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Hariharan Easwaran","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"last","author":{"id":"https://openalex.org/A5058612163","display_name":"Stephen B. Baylin","orcid":"https://orcid.org/0000-0003-3697-3798","observed_orcids":["https://orcid.org/0000-0003-3697-3798"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Stephen B. Baylin","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]}],"institutions":[],"countries_distinct_count":0,"institutions_distinct_count":0,"corresponding_author_ids":[],"corresponding_institution_ids":[],"apc_list":null,"apc_paid":null,"fwci":null,"has_fulltext":false,"cited_by_count":0,"citation_normalized_percentile":null,"cited_by_percentile_year":null,"biblio":{"volume":null,"issue":null,"first_page":null,"last_page":null},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10269","display_name":"Epigenetics and DNA Methylation","score":0.9937000274658203,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T10269","display_name":"Epigenetics and DNA Methylation","score":0.9937000274658203,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T13157","display_name":"Cancer-related gene regulation","score":0.00139999995008111,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T11736","display_name":"Histone Deacetylase Inhibitors Research","score":0.0005000000237487257,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/h3k4-trimethylation","display_name":"H3K4 trimethylation","score":0.9850000143051147},{"id":"https://openalex.org/keywords/decitabine","display_name":"decitabine","score":0.9279999732971191},{"id":"https://openalex.org/keywords/dna-methylation","display_name":"DNA methylation","score":0.593999981880188},{"id":"https://openalex.org/keywords/epigenetic-reprogramming","display_name":"epigenetic reprogramming","score":0.7929999828338623},{"id":"https://openalex.org/keywords/breast-cancer-cell-lines","display_name":"breast cancer cell lines","score":0.9610000252723694},{"id":"https://openalex.org/keywords/cell-viability","display_name":"cell viability","score":0.8759999871253967},{"id":"https://openalex.org/keywords/histone-demethylase","display_name":"histone demethylase","score":0.7300000190734863}],"concepts":[{"id":"https://openalex.org/C2777844706","wikidata":"https://www.wikidata.org/wiki/Q422504","display_name":"Deoxycytidine","level":4,"score":0.6354131102561951},{"id":"https://openalex.org/C45235069","wikidata":"https://www.wikidata.org/wiki/Q278425","display_name":"Table (database)","level":2,"score":0.6045886278152466},{"id":"https://openalex.org/C153911025","wikidata":"https://www.wikidata.org/wiki/Q7202","display_name":"Molecular biology","level":1,"score":0.4478849768638611},{"id":"https://openalex.org/C185592680","wikidata":"https://www.wikidata.org/wiki/Q2329","display_name":"Chemistry","level":0,"score":0.39179766178131104},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.32969242334365845},{"id":"https://openalex.org/C54355233","wikidata":"https://www.wikidata.org/wiki/Q7162","display_name":"Genetics","level":1,"score":0.21636107563972473},{"id":"https://openalex.org/C121608353","wikidata":"https://www.wikidata.org/wiki/Q12078","display_name":"Cancer","level":2,"score":0.16528105735778809},{"id":"https://openalex.org/C41008148","wikidata":"https://www.wikidata.org/wiki/Q21198","display_name":"Computer science","level":0,"score":0.15038684010505676},{"id":"https://openalex.org/C77088390","wikidata":"https://www.wikidata.org/wiki/Q8513","display_name":"Database","level":1,"score":0.10983330011367798},{"id":"https://openalex.org/C2780258809","wikidata":"https://www.wikidata.org/wiki/Q414143","display_name":"Gemcitabine","level":3,"score":0.05441078543663025}],"mesh":[],"locations_count":3,"locations":[{"id":"doi:10.1158/0008-5472.22411056","doi":"https://doi.org/10.1158/0008-5472.22411056","is_oa":true,"landing_page_url":"https://doi.org/10.1158/0008-5472.22411056","pdf_url":"https://aacr.figshare.com/articles/journal_contribution/Supplementary_Tables_from_A_KDM5_Inhibitor_Increases_Global_H3K4_Trimethylation_Occupancy_and_Enhances_the_Biological_Efficacy_of_5-Aza-2_-Deoxycytidine/22411056/1/files/39856974.pdf","source":null,"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"acceptedVersion","is_accepted":true,"is_published":false,"raw_source_name":"American Association for Cancer Research","raw_type":"posted-content"},{"id":"doi:10.1158/0008-5472.22411056.v1","doi":"https://doi.org/10.1158/0008-5472.22411056.v1","is_oa":true,"landing_page_url":"http://dx.doi.org/10.1158/0008-5472.22411056.v1","pdf_url":null,"source":null,"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"acceptedVersion","is_accepted":true,"is_published":false,"raw_source_name":"American Association for Cancer Research","raw_type":"posted-content"},{"id":"pmh:oai:figshare.com:article/22411056","doi":null,"is_oa":true,"landing_page_url":"https://figshare.com/articles/journal_contribution/Supplementary_Tables_from_A_KDM5_Inhibitor_Increases_Global_H3K4_Trimethylation_Occupancy_and_Enhances_the_Biological_Efficacy_of_5-Aza-2_-Deoxycytidine/22411056","pdf_url":null,"source":{"id":"https://openalex.org/S4377196282","display_name":"Figshare","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I4210132348","host_organization_name":"Figshare (United Kingdom)","host_organization_lineage":["https://openalex.org/I4210132348"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"","raw_type":"Text"}],"best_oa_location":{"id":"doi:10.1158/0008-5472.22411056","doi":"https://doi.org/10.1158/0008-5472.22411056","is_oa":true,"landing_page_url":"https://doi.org/10.1158/0008-5472.22411056","pdf_url":"https://aacr.figshare.com/articles/journal_contribution/Supplementary_Tables_from_A_KDM5_Inhibitor_Increases_Global_H3K4_Trimethylation_Occupancy_and_Enhances_the_Biological_Efficacy_of_5-Aza-2_-Deoxycytidine/22411056/1/files/39856974.pdf","source":null,"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"acceptedVersion","is_accepted":true,"is_published":false,"raw_source_name":"American Association for Cancer Research","raw_type":"posted-content"},"sustainable_development_goals":[{"display_name":"Good health and well-being","score":0.8048999905586243,"id":"https://metadata.un.org/sdg/3"}],"study_designs":[],"awards":[],"funders":[],"has_content":{"pdf":true,"grobid_xml":true},"content_urls":{"pdf":"https://content.openalex.org/works/W4361850962.pdf","grobid_xml":"https://content.openalex.org/works/W4361850962.grobid-xml"},"referenced_works_count":0,"referenced_works":[],"related_works":["https://openalex.org/W4362318486","https://openalex.org/W4361234404","https://openalex.org/W4362324210","https://openalex.org/W4361834591","https://openalex.org/W4362325959","https://openalex.org/W4361851022","https://openalex.org/W4361863829","https://openalex.org/W2780724534","https://openalex.org/W2395554454","https://openalex.org/W2980428253"],"abstract_inverted_index":{"Contains":[0],"Tables":[1],"S1":[2],"and":[3],"S2.":[4],"Supplementary":[5,12],"Table":[6,13],"1:":[7],"List":[8],"of":[9,16],"PCR":[10],"primers.":[11],"2:":[14],"Sensitivity":[15],"Breast":[17],"Cancer":[18],"Cell":[19,23],"Lines":[20],"to":[21,29],"CPI-455":[22,30],"Viability":[24],"was":[25],"measured":[26],"following":[27],"exposure":[28],"for":[31],"8":[32],"days.":[33]},"counts_by_year":[],"updated_date":"2026-11-04T10:54:05.112534","created_date":"2023-04-05T00:00:00"}