{"id":"https://openalex.org/W4361848851","doi":"https://doi.org/10.1158/0008-5472.22405548","title":"Supplementary Figure S1 from Hepatocellular Shuttling and Recirculation of Sorafenib-Glucuronide Is Dependent on Abcc2, Abcc3, and Oatp1a/1b","display_name":"Supplementary Figure S1 from Hepatocellular Shuttling and Recirculation of Sorafenib-Glucuronide Is Dependent on Abcc2, Abcc3, and Oatp1a/1b","publication_year":2023,"publication_date":"2023-03-30","ids":{"openalex":"https://openalex.org/W4361848851","doi":"https://doi.org/10.1158/0008-5472.22405548"},"language":"en","primary_location":{"id":"doi:10.1158/0008-5472.22405548","doi":"https://doi.org/10.1158/0008-5472.22405548","is_oa":true,"landing_page_url":"https://doi.org/10.1158/0008-5472.22405548","pdf_url":null,"source":null,"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"acceptedVersion","is_accepted":true,"is_published":false,"raw_source_name":"American Association for Cancer Research","raw_type":"posted-content"},"volume":null,"type":"supplementary-materials","is_traditional":false,"indexed_in":["crossref"],"open_access":{"is_oa":true,"oa_status":"gold","oa_url":"https://doi.org/10.1158/0008-5472.22405548","any_repository_has_fulltext":null},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5113057203","display_name":"Aksana Vasilyeva","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Aksana Vasilyeva","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5010596311","display_name":"Selvi Durmu\u015f","orcid":"https://orcid.org/0000-0003-3792-1607","observed_orcids":["https://orcid.org/0000-0003-3792-1607"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Selvi Durmus","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5016647580","display_name":"Lie Li","orcid":"https://orcid.org/0000-0003-1508-5484","observed_orcids":["https://orcid.org/0000-0003-1508-5484"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Lie Li","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5050563360","display_name":"Els Wagenaar","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Els Wagenaar","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5077955893","display_name":"Shuiying Hu","orcid":"https://orcid.org/0000-0002-9806-7734","observed_orcids":["https://orcid.org/0000-0002-9806-7734"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Shuiying Hu","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":null,"display_name":"Alice A. Gibson","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Alice A. Gibson","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5039997334","display_name":"John Carl Panetta","orcid":"https://orcid.org/0000-0003-1308-7208","observed_orcids":["https://orcid.org/0000-0003-1308-7208"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"John C. Panetta","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5054253771","display_name":"Sridhar Mani","orcid":"https://orcid.org/0000-0003-4132-6157","observed_orcids":["https://orcid.org/0000-0003-4132-6157"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Sridhar Mani","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5065279964","display_name":"Alex Sparreboom","orcid":"https://orcid.org/0000-0003-2660-6644","observed_orcids":["https://orcid.org/0000-0003-2660-6644"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Alex Sparreboom","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5077260725","display_name":"Sharyn D. Baker","orcid":"https://orcid.org/0000-0003-3062-3252","observed_orcids":["https://orcid.org/0000-0003-3062-3252"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Sharyn D. Baker","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"last","author":{"id":"https://openalex.org/A5045217576","display_name":"Alfred H. Schinkel","orcid":"https://orcid.org/0000-0002-4215-8602","observed_orcids":["https://orcid.org/0000-0002-4215-8602"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Alfred H. Schinkel","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]}],"institutions":[],"countries_distinct_count":0,"institutions_distinct_count":0,"corresponding_author_ids":[],"corresponding_institution_ids":[],"apc_list":null,"apc_paid":null,"fwci":null,"has_fulltext":false,"cited_by_count":0,"citation_normalized_percentile":null,"cited_by_percentile_year":null,"biblio":{"volume":null,"issue":null,"first_page":null,"last_page":null},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10570","display_name":"Drug Transport and Resistance Mechanisms","score":0.9994999766349792,"subfield":{"id":"https://openalex.org/subfields/2730","display_name":"Oncology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T10570","display_name":"Drug Transport and Resistance Mechanisms","score":0.9994999766349792,"subfield":{"id":"https://openalex.org/subfields/2730","display_name":"Oncology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10375","display_name":"Pharmacogenetics and Drug Metabolism","score":0.00039999998989515007,"subfield":{"id":"https://openalex.org/subfields/3004","display_name":"Pharmacology"},"field":{"id":"https://openalex.org/fields/30","display_name":"Pharmacology, Toxicology and Pharmaceutics"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10073","display_name":"Hepatocellular Carcinoma Treatment and Prognosis","score":0.0,"subfield":{"id":"https://openalex.org/subfields/2721","display_name":"Hepatology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/mrp2","display_name":"MRP2","score":0.7390000224113464},{"id":"https://openalex.org/keywords/abcc3","display_name":"ABCC3","score":0.9990000128746033},{"id":"https://openalex.org/keywords/oatp1b","display_name":"OATP1B","score":0.9990000128746033},{"id":"https://openalex.org/keywords/hepatic-uptake","display_name":"hepatic uptake","score":0.8650000095367432},{"id":"https://openalex.org/keywords/biliary-excretion","display_name":"biliary excretion","score":0.996999979019165},{"id":"https://openalex.org/keywords/abc-transporters","display_name":"ABC transporters","score":0.6380000114440918}],"concepts":[{"id":"https://openalex.org/C2778695046","wikidata":"https://www.wikidata.org/wiki/Q421136","display_name":"Sorafenib","level":3,"score":0.8814342021942139},{"id":"https://openalex.org/C36201501","wikidata":"https://www.wikidata.org/wiki/Q17907816","display_name":"Multidrug resistance-associated protein 2","level":5,"score":0.7295905351638794},{"id":"https://openalex.org/C2779186261","wikidata":"https://www.wikidata.org/wiki/Q137786","display_name":"Glucuronide","level":3,"score":0.5818498134613037},{"id":"https://openalex.org/C10146269","wikidata":"https://www.wikidata.org/wiki/Q185557","display_name":"Excretion","level":2,"score":0.5688880681991577},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.46923643350601196},{"id":"https://openalex.org/C185592680","wikidata":"https://www.wikidata.org/wiki/Q2329","display_name":"Chemistry","level":0,"score":0.4590223729610443},{"id":"https://openalex.org/C2778019345","wikidata":"https://www.wikidata.org/wiki/Q1148337","display_name":"Hepatocellular carcinoma","level":2,"score":0.28968971967697144},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.2834130525588989},{"id":"https://openalex.org/C55493867","wikidata":"https://www.wikidata.org/wiki/Q7094","display_name":"Biochemistry","level":1,"score":0.1305084228515625},{"id":"https://openalex.org/C62231903","wikidata":"https://www.wikidata.org/wiki/Q1057","display_name":"Metabolism","level":2,"score":0.09807482361793518},{"id":"https://openalex.org/C149011108","wikidata":"https://www.wikidata.org/wiki/Q652985","display_name":"Transporter","level":3,"score":0.08514729142189026},{"id":"https://openalex.org/C104317684","wikidata":"https://www.wikidata.org/wiki/Q7187","display_name":"Gene","level":2,"score":0.0},{"id":"https://openalex.org/C44312359","wikidata":"https://www.wikidata.org/wiki/Q286958","display_name":"ATP-binding cassette transporter","level":4,"score":0.0}],"mesh":[],"locations_count":2,"locations":[{"id":"doi:10.1158/0008-5472.22405548","doi":"https://doi.org/10.1158/0008-5472.22405548","is_oa":true,"landing_page_url":"https://doi.org/10.1158/0008-5472.22405548","pdf_url":null,"source":null,"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"acceptedVersion","is_accepted":true,"is_published":false,"raw_source_name":"American Association for Cancer Research","raw_type":"posted-content"},{"id":"doi:10.1158/0008-5472.22405548.v1","doi":"https://doi.org/10.1158/0008-5472.22405548.v1","is_oa":true,"landing_page_url":"https://doi.org/10.1158/0008-5472.22405548.v1","pdf_url":null,"source":null,"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"acceptedVersion","is_accepted":true,"is_published":false,"raw_source_name":"American Association for Cancer Research","raw_type":"posted-content"}],"best_oa_location":{"id":"doi:10.1158/0008-5472.22405548","doi":"https://doi.org/10.1158/0008-5472.22405548","is_oa":true,"landing_page_url":"https://doi.org/10.1158/0008-5472.22405548","pdf_url":null,"source":null,"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"acceptedVersion","is_accepted":true,"is_published":false,"raw_source_name":"American Association for Cancer Research","raw_type":"posted-content"},"sustainable_development_goals":[{"display_name":"Good health and well-being","score":0.8560000061988831,"id":"https://metadata.un.org/sdg/3"}],"study_designs":[],"awards":[],"funders":[],"has_content":{"grobid_xml":false,"pdf":false},"content_urls":null,"referenced_works_count":0,"referenced_works":[],"related_works":["https://openalex.org/W4392687374","https://openalex.org/W1544537424","https://openalex.org/W7100404331","https://openalex.org/W2152540368","https://openalex.org/W2611065138","https://openalex.org/W2037527490","https://openalex.org/W2049056547","https://openalex.org/W7098059035","https://openalex.org/W4361944564","https://openalex.org/W2317722301"],"abstract_inverted_index":{"Hepatic":[0],"uptake":[1],"and":[2,7],"biliary":[3],"excretion":[4],"in":[5],"wildtype":[6],"Abcc2(-/-)":[8],"mice.":[9]},"counts_by_year":[],"updated_date":"2026-11-04T10:54:05.112534","created_date":"2023-04-05T00:00:00"}