{"id":"https://openalex.org/W4361822639","doi":"https://doi.org/10.1158/1055-9965.c.6514795","title":"Data from Adherence to Dietary and Lifestyle Recommendations and Prostate Cancer Risk in the Prostate Testing for Cancer and Treatment (ProtecT) Trial","display_name":"Data from Adherence to Dietary and Lifestyle Recommendations and Prostate Cancer Risk in the Prostate Testing for Cancer and Treatment (ProtecT) Trial","publication_year":2023,"publication_date":"2023-03-31","ids":{"openalex":"https://openalex.org/W4361822639","doi":"https://doi.org/10.1158/1055-9965.c.6514795"},"language":"en","primary_location":{"id":"doi:10.1158/1055-9965.c.6514795","doi":"https://doi.org/10.1158/1055-9965.c.6514795","is_oa":true,"landing_page_url":"https://doi.org/10.1158/1055-9965.c.6514795","pdf_url":null,"source":null,"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"acceptedVersion","is_accepted":true,"is_published":false,"raw_source_name":"American Association for Cancer Research","raw_type":"posted-content"},"volume":null,"type":"other","indexed_in":["crossref"],"open_access":{"is_oa":true,"oa_status":"gold","oa_url":"https://doi.org/10.1158/1055-9965.c.6514795","any_repository_has_fulltext":null},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5071130679","display_name":"Vanessa Er","orcid":"https://orcid.org/0000-0002-0649-1846","observed_orcids":["https://orcid.org/0000-0002-0649-1846"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Vanessa Er","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5069462410","display_name":"J. Athene Lane","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"J. Athene Lane","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5065571043","display_name":"Richard Michael Martin","orcid":"https://orcid.org/0000-0002-7992-7719","observed_orcids":["https://orcid.org/0000-0002-7992-7719"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Richard M. Martin","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5083203767","display_name":"Pauline M. Emmett","orcid":"https://orcid.org/0000-0003-1076-4779","observed_orcids":["https://orcid.org/0000-0003-1076-4779"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Pauline Emmett","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5038137180","display_name":"Rebecca Gilbert","orcid":"https://orcid.org/0000-0003-4274-0990","observed_orcids":["https://orcid.org/0000-0003-4274-0990"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Rebecca Gilbert","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5040091822","display_name":"KERRY N. L. AVERY","orcid":"https://orcid.org/0000-0001-5477-2418","observed_orcids":["https://orcid.org/0000-0001-5477-2418"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Kerry N.L. Avery","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5023577572","display_name":"Eleanor I. Walsh","orcid":"https://orcid.org/0000-0001-7696-3661","observed_orcids":["https://orcid.org/0000-0001-7696-3661"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Eleanor Walsh","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5049636639","display_name":"Jenny Donovan","orcid":"https://orcid.org/0000-0002-6488-5472","observed_orcids":["https://orcid.org/0000-0002-6488-5472"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Jenny L. Donovan","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5090783984","display_name":"David Edgar Neal","orcid":"https://orcid.org/0000-0002-6033-5086","observed_orcids":["https://orcid.org/0000-0002-6033-5086"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"David E. Neal","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5012694886","display_name":"Freddie Charles Hamdy","orcid":"https://orcid.org/0000-0003-2627-2154","observed_orcids":["https://orcid.org/0000-0003-2627-2154"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Freddie C. Hamdy","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"last","author":{"id":"https://openalex.org/A5065323010","display_name":"Mona Jeffreys","orcid":"https://orcid.org/0000-0002-2617-0361","observed_orcids":["https://orcid.org/0000-0002-2617-0361"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Mona Jeffreys","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]}],"institutions":[],"countries_distinct_count":0,"institutions_distinct_count":0,"corresponding_author_ids":[],"corresponding_institution_ids":[],"apc_list":null,"apc_paid":null,"fwci":null,"has_fulltext":false,"cited_by_count":0,"citation_normalized_percentile":null,"cited_by_percentile_year":null,"biblio":{"volume":null,"issue":null,"first_page":null,"last_page":null},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10866","display_name":"Nutritional Studies and Diet","score":0.9926999807357788,"subfield":{"id":"https://openalex.org/subfields/2739","display_name":"Public Health, Environmental and Occupational Health"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T10866","display_name":"Nutritional Studies and Diet","score":0.9926999807357788,"subfield":{"id":"https://openalex.org/subfields/2739","display_name":"Public Health, Environmental and Occupational Health"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10124","display_name":"Prostate Cancer Diagnosis and Treatment","score":0.003100000089034438,"subfield":{"id":"https://openalex.org/subfields/2740","display_name":"Pulmonary and Respiratory Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T12103","display_name":"Cancer Risks and Factors","score":0.0017000000225380063,"subfield":{"id":"https://openalex.org/subfields/2730","display_name":"Oncology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/prostate-cancer","display_name":"prostate cancer","score":0.796999990940094},{"id":"https://openalex.org/keywords/dietary-adherence","display_name":"dietary adherence","score":0.6290000081062317},{"id":"https://openalex.org/keywords/lifestyle-advice","display_name":"lifestyle advice","score":0.7710000276565552},{"id":"https://openalex.org/keywords/wcrf-aicr-recommendations","display_name":"WCRF/AICR recommendations","score":0.875},{"id":"https://openalex.org/keywords/cancer-prevention","display_name":"cancer prevention","score":0.7770000100135803},{"id":"https://openalex.org/keywords/plant-based-foods","display_name":"plant-based foods","score":0.9079999923706055},{"id":"https://openalex.org/keywords/tomato-products","display_name":"tomato products","score":0.9980000257492065},{"id":"https://openalex.org/keywords/prostate-specific-antigen","display_name":"prostate-specific antigen","score":0.6830000281333923},{"id":"https://openalex.org/keywords/protect-trial","display_name":"PROTECT trial","score":0.7979999780654907},{"id":"https://openalex.org/keywords/cancer-risk","display_name":"cancer risk","score":0.5529999732971191}],"concepts":[{"id":"https://openalex.org/C2780192828","wikidata":"https://www.wikidata.org/wiki/Q181257","display_name":"Prostate cancer","level":3,"score":0.8655216693878174},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.7083842158317566},{"id":"https://openalex.org/C121608353","wikidata":"https://www.wikidata.org/wiki/Q12078","display_name":"Cancer","level":2,"score":0.6186431646347046},{"id":"https://openalex.org/C2776235491","wikidata":"https://www.wikidata.org/wiki/Q9625","display_name":"Prostate","level":3,"score":0.5209882855415344},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.4816838204860687},{"id":"https://openalex.org/C2780234812","wikidata":"https://www.wikidata.org/wiki/Q1787013","display_name":"Cancer prevention","level":3,"score":0.4261765480041504},{"id":"https://openalex.org/C143998085","wikidata":"https://www.wikidata.org/wiki/Q162555","display_name":"Oncology","level":1,"score":0.36566418409347534},{"id":"https://openalex.org/C29456083","wikidata":"https://www.wikidata.org/wiki/Q1221899","display_name":"Gynecology","level":1,"score":0.3421770930290222}],"mesh":[],"locations_count":2,"locations":[{"id":"doi:10.1158/1055-9965.c.6514795","doi":"https://doi.org/10.1158/1055-9965.c.6514795","is_oa":true,"landing_page_url":"https://doi.org/10.1158/1055-9965.c.6514795","pdf_url":null,"source":null,"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"acceptedVersion","is_accepted":true,"is_published":false,"raw_source_name":"American Association for Cancer Research","raw_type":"posted-content"},{"id":"doi:10.1158/1055-9965.c.6514795.v1","doi":"https://doi.org/10.1158/1055-9965.c.6514795.v1","is_oa":true,"landing_page_url":"https://doi.org/10.1158/1055-9965.c.6514795.v1","pdf_url":null,"source":null,"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"acceptedVersion","is_accepted":true,"is_published":false,"raw_source_name":"American Association for Cancer Research","raw_type":"posted-content"}],"best_oa_location":{"id":"doi:10.1158/1055-9965.c.6514795","doi":"https://doi.org/10.1158/1055-9965.c.6514795","is_oa":true,"landing_page_url":"https://doi.org/10.1158/1055-9965.c.6514795","pdf_url":null,"source":null,"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"acceptedVersion","is_accepted":true,"is_published":false,"raw_source_name":"American Association for Cancer Research","raw_type":"posted-content"},"sustainable_development_goals":[{"score":1.0,"display_name":"Good health and well-being","id":"https://metadata.un.org/sdg/3"}],"study_designs":[],"awards":[],"funders":[],"has_content":{"pdf":false,"grobid_xml":false},"content_urls":null,"referenced_works_count":0,"referenced_works":[],"related_works":["https://openalex.org/W7099899011","https://openalex.org/W2111329400","https://openalex.org/W2066611673","https://openalex.org/W3012308890","https://openalex.org/W4399848892","https://openalex.org/W4416386413","https://openalex.org/W2612368484","https://openalex.org/W3213373283","https://openalex.org/W4229332055","https://openalex.org/W2977357856"],"abstract_inverted_index":{"Abstract":[0],"Background:":[1],"The":[2,109],"World":[3],"Cancer":[4,13,263],"Research":[5,14],"Fund":[6],"(WCRF)":[7],"and":[8,39,66,101,191,234],"the":[9,36,70,98,102,138,216,247],"American":[10],"Institute":[11],"for":[12,19,253],"(AICR)":[15],"published":[16],"eight":[17],"recommendations":[18,38,100,173,220,249,259],"cancer":[20,29,42,49,64,77,104,111,122,160,211,255],"prevention,":[21],"but":[22,137],"they":[23],"are":[24],"not":[25,143],"targeted":[26],"at":[27],"prostate":[28,41,48,63,76,89,103,110,121,159,210,217,227,243,254],"prevention.":[30,256],"We":[31,52,73],"investigated":[32],"whether":[33],"adherence":[34,96,171,195],"to":[35,94,97,172,174,215],"WCRF/AICR":[37,99,139,248],"a":[40,54,75],"dietary":[43,78,83,105,112,219,258],"index":[44,79,106,113,140,181],"is":[45,251],"associated":[46,87,116,207,222],"with":[47,88,117,208,223],"risk.":[50,212],"Methods:":[51],"conducted":[53],"nested":[55],"case\u2013control":[56],"study":[57],"of":[58,120,226,231],"1,806":[59],"prostate-specific":[60],"antigen":[61],"(PSA)\u2013detected":[62],"cases":[65],"12,005":[67],"controls":[68],"in":[69,156,237],"ProtecT":[71],"trial.":[72],"developed":[74],"by":[80,158],"incorporating":[81],"three":[82],"factors":[84],"most":[85],"strongly":[86],"cancer.":[90,228,244],"Scores":[91],"were":[92],"computed":[93],"quantify":[95],"separately.":[107],"Results:":[108],"score":[114,126,141,182],"was":[115,142,153,205,221],"decreased":[118,224],"risk":[119,225],"[OR":[123],"per":[124,179],"1":[125],"increment:":[127,183],"0.91;":[128],"95%":[129,146,185,199],"confidence":[130],"interval":[131],"(CI):":[132],"0.84\u20130.99;":[133],"Ptrend":[134,149,188],"=":[135,150,163,168,189,203],"0.04]":[136],"(OR:":[144],"0.99;":[145],"CI:":[147,186,200],"0.94\u20131.05;":[148],"0.71).":[151],"There":[152],"no":[154],"heterogeneity":[155],"association":[157],"stage":[161],"(P":[162,167],"0.81)":[164],"or":[165],"grade":[166],"0.61).":[169],"Greater":[170],"increase":[175],"plant":[176,232],"foods":[177,233],"(OR":[178,194],"0.25":[180],"0.94;":[184],"0.89\u20130.99;":[187],"0.02)":[190,204],"tomato":[192,235],"products":[193,236],"vs.":[196],"nonadherence:":[197],"0.82;":[198],"0.70\u20130.97;":[201],"P":[202],"inversely":[206],"overall":[209],"Conclusions:":[213],"Adherence":[214],"cancer\u2013specific":[218],"High":[229],"intake":[230],"particular":[238],"may":[239],"help":[240],"protect":[241],"against":[242],"Impact:":[245],"Meeting":[246],"alone":[250],"insufficient":[252],"Additional":[257],"should":[260],"be":[261],"developed.":[262],"Epidemiol":[264],"Biomarkers":[265],"Prev;":[266],"23(10);":[267],"2066\u201377.":[268],"\u00a92014":[269],"AACR.":[270]},"counts_by_year":[],"updated_date":"2026-11-04T10:54:05.112534","created_date":"2023-04-05T00:00:00"}