{"id":"https://openalex.org/W4361815047","doi":"https://doi.org/10.1158/1078-0432.22480164","title":"Figure S1 from CAR T cells Targeting Human Immunoglobulin Light Chains Eradicate Mature B-cell Malignancies While Sparing a Subset of Normal B Cells","display_name":"Figure S1 from CAR T cells Targeting Human Immunoglobulin Light Chains Eradicate Mature B-cell Malignancies While Sparing a Subset of Normal B Cells","publication_year":2023,"publication_date":"2023-03-31","ids":{"openalex":"https://openalex.org/W4361815047","doi":"https://doi.org/10.1158/1078-0432.22480164"},"language":"en","primary_location":{"id":"doi:10.1158/1078-0432.22480164","doi":"https://doi.org/10.1158/1078-0432.22480164","is_oa":true,"landing_page_url":"https://doi.org/10.1158/1078-0432.22480164","pdf_url":null,"source":null,"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"acceptedVersion","is_accepted":true,"is_published":false,"raw_source_name":"American Association for Cancer Research","raw_type":"posted-content"},"volume":null,"type":"other","indexed_in":["crossref"],"open_access":{"is_oa":true,"oa_status":"gold","oa_url":"https://doi.org/10.1158/1078-0432.22480164","any_repository_has_fulltext":null},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5069413431","display_name":"Raghuveer Ranganathan","orcid":"https://orcid.org/0000-0001-7190-5809","observed_orcids":["https://orcid.org/0000-0001-7190-5809"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Raghuveer Ranganathan","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5058775810","display_name":"Peishun Shou","orcid":"https://orcid.org/0000-0001-7685-7471","observed_orcids":["https://orcid.org/0000-0001-7685-7471"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Peishun Shou","raw_affiliation_strings":[],"raw_orcid":"https://orcid.org/0000-0001-7685-7471","affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5040285533","display_name":"Sarah Ahn","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Sarah Ahn","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5065371838","display_name":"Chuang Sun","orcid":"https://orcid.org/0000-0002-6156-0699","observed_orcids":["https://orcid.org/0000-0002-6156-0699"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Chuang Sun","raw_affiliation_strings":[],"raw_orcid":"https://orcid.org/0000-0002-6156-0699","affiliations":[]},{"author_position":"middle","author":{"id":null,"display_name":"John West","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"John West","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5065544223","display_name":"Barbara Savoldo","orcid":"https://orcid.org/0000-0002-7571-3887","observed_orcids":["https://orcid.org/0000-0002-7571-3887"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Barbara Savoldo","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"last","author":{"id":"https://openalex.org/A5023649972","display_name":"Gianpietro Dotti","orcid":"https://orcid.org/0000-0002-2639-8526","observed_orcids":["https://orcid.org/0000-0002-2639-8526"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Gianpietro Dotti","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]}],"institutions":[],"countries_distinct_count":0,"institutions_distinct_count":0,"corresponding_author_ids":[],"corresponding_institution_ids":[],"apc_list":null,"apc_paid":null,"fwci":null,"has_fulltext":false,"cited_by_count":0,"citation_normalized_percentile":null,"cited_by_percentile_year":null,"biblio":{"volume":null,"issue":null,"first_page":null,"last_page":null},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T11491","display_name":"CAR-T cell therapy research","score":0.9980000257492065,"subfield":{"id":"https://openalex.org/subfields/2730","display_name":"Oncology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T11491","display_name":"CAR-T cell therapy research","score":0.9980000257492065,"subfield":{"id":"https://openalex.org/subfields/2730","display_name":"Oncology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10031","display_name":"T-cell and B-cell Immunology","score":0.000699999975040555,"subfield":{"id":"https://openalex.org/subfields/2403","display_name":"Immunology"},"field":{"id":"https://openalex.org/fields/24","display_name":"Immunology and Microbiology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10580","display_name":"Immunotherapy and Immune Responses","score":0.00019999999494757503,"subfield":{"id":"https://openalex.org/subfields/2403","display_name":"Immunology"},"field":{"id":"https://openalex.org/fields/24","display_name":"Immunology and Microbiology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/chimeric-antigen-receptor-t-cells","display_name":"chimeric antigen receptor T cells","score":0.9919999837875366},{"id":"https://openalex.org/keywords/b-cell-malignancies","display_name":"B-cell malignancies","score":0.8970000147819519},{"id":"https://openalex.org/keywords/normal-b-cells","display_name":"normal B cells","score":0.765999972820282}],"concepts":[{"id":"https://openalex.org/C36394416","wikidata":"https://www.wikidata.org/wiki/Q949267","display_name":"Immunoglobulin light chain","level":3,"score":0.6960467100143433},{"id":"https://openalex.org/C159654299","wikidata":"https://www.wikidata.org/wiki/Q79460","display_name":"Antibody","level":2,"score":0.6424109935760498},{"id":"https://openalex.org/C24530287","wikidata":"https://www.wikidata.org/wiki/Q424204","display_name":"Transmembrane protein","level":3,"score":0.5296494960784912},{"id":"https://openalex.org/C2778453870","wikidata":"https://www.wikidata.org/wiki/Q188930","display_name":"B cell","level":3,"score":0.48019540309906006},{"id":"https://openalex.org/C118892022","wikidata":"https://www.wikidata.org/wiki/Q7834587","display_name":"Transmembrane domain","level":3,"score":0.47119829058647156},{"id":"https://openalex.org/C149774189","wikidata":"https://www.wikidata.org/wiki/Q24770541","display_name":"Immunoglobulin domain","level":3,"score":0.46443992853164673},{"id":"https://openalex.org/C36503486","wikidata":"https://www.wikidata.org/wiki/Q11235244","display_name":"Domain (mathematical analysis)","level":2,"score":0.42535510659217834},{"id":"https://openalex.org/C153911025","wikidata":"https://www.wikidata.org/wiki/Q7202","display_name":"Molecular biology","level":1,"score":0.4172842502593994},{"id":"https://openalex.org/C502942594","wikidata":"https://www.wikidata.org/wiki/Q3421914","display_name":"Cancer research","level":1,"score":0.3631059527397156},{"id":"https://openalex.org/C185592680","wikidata":"https://www.wikidata.org/wiki/Q2329","display_name":"Chemistry","level":0,"score":0.35741856694221497},{"id":"https://openalex.org/C95444343","wikidata":"https://www.wikidata.org/wiki/Q7141","display_name":"Cell biology","level":1,"score":0.33779996633529663},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.3244559168815613},{"id":"https://openalex.org/C203014093","wikidata":"https://www.wikidata.org/wiki/Q101929","display_name":"Immunology","level":1,"score":0.30240699648857117},{"id":"https://openalex.org/C104317684","wikidata":"https://www.wikidata.org/wiki/Q7187","display_name":"Gene","level":2,"score":0.18982434272766113},{"id":"https://openalex.org/C54355233","wikidata":"https://www.wikidata.org/wiki/Q7162","display_name":"Genetics","level":1,"score":0.1770322620868683},{"id":"https://openalex.org/C170493617","wikidata":"https://www.wikidata.org/wiki/Q208467","display_name":"Receptor","level":2,"score":0.16288471221923828},{"id":"https://openalex.org/C33923547","wikidata":"https://www.wikidata.org/wiki/Q395","display_name":"Mathematics","level":0,"score":0.1534138321876526},{"id":"https://openalex.org/C134306372","wikidata":"https://www.wikidata.org/wiki/Q7754","display_name":"Mathematical analysis","level":1,"score":0.0}],"mesh":[],"locations_count":1,"locations":[{"id":"doi:10.1158/1078-0432.22480164","doi":"https://doi.org/10.1158/1078-0432.22480164","is_oa":true,"landing_page_url":"https://doi.org/10.1158/1078-0432.22480164","pdf_url":null,"source":null,"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"acceptedVersion","is_accepted":true,"is_published":false,"raw_source_name":"American Association for Cancer Research","raw_type":"posted-content"}],"best_oa_location":{"id":"doi:10.1158/1078-0432.22480164","doi":"https://doi.org/10.1158/1078-0432.22480164","is_oa":true,"landing_page_url":"https://doi.org/10.1158/1078-0432.22480164","pdf_url":null,"source":null,"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"acceptedVersion","is_accepted":true,"is_published":false,"raw_source_name":"American Association for Cancer Research","raw_type":"posted-content"},"sustainable_development_goals":[{"score":0.9763000011444092,"display_name":"Good health and well-being","id":"https://metadata.un.org/sdg/3"}],"study_designs":[],"awards":[],"funders":[],"has_content":{"pdf":false,"grobid_xml":false},"content_urls":null,"referenced_works_count":0,"referenced_works":[],"related_works":["https://openalex.org/W4361815086","https://openalex.org/W4361815783","https://openalex.org/W4361815116","https://openalex.org/W3156298502","https://openalex.org/W4361815777","https://openalex.org/W4361815293","https://openalex.org/W2531541799","https://openalex.org/W2912805574","https://openalex.org/W3194106653","https://openalex.org/W2087567696"],"abstract_inverted_index":{"Modifications":[0],"of":[1],"the":[2],"hinge":[3],"and":[4],"transmembrane":[5],"domain":[6]},"counts_by_year":[],"updated_date":"2026-09-27T08:07:27.782135","created_date":"2023-04-05T00:00:00"}