{"id":"https://openalex.org/W4361272045","doi":"https://doi.org/10.1158/2767-9764.22361308","title":"Figure S1 from IL1\u03b2 Expression Driven by Androgen Receptor Absence or Inactivation Promotes Prostate Cancer Bone Metastasis","display_name":"Figure S1 from IL1\u03b2 Expression Driven by Androgen Receptor Absence or Inactivation Promotes Prostate Cancer Bone Metastasis","publication_year":2023,"publication_date":"2023-03-30","ids":{"openalex":"https://openalex.org/W4361272045","doi":"https://doi.org/10.1158/2767-9764.22361308"},"language":"en","primary_location":{"id":"doi:10.1158/2767-9764.22361308","doi":"https://doi.org/10.1158/2767-9764.22361308","is_oa":true,"landing_page_url":"http://dx.doi.org/10.1158/2767-9764.22361308","pdf_url":null,"source":null,"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"acceptedVersion","is_accepted":true,"is_published":false,"raw_source_name":"American Association for Cancer Research","raw_type":"posted-content"},"volume":null,"type":"other","is_traditional":false,"indexed_in":["crossref"],"open_access":{"is_oa":true,"oa_status":"gold","oa_url":"http://dx.doi.org/10.1158/2767-9764.22361308","any_repository_has_fulltext":null},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5034449837","display_name":"Anthony DiNatale","orcid":"https://orcid.org/0000-0003-3221-7506","observed_orcids":["https://orcid.org/0000-0003-3221-7506"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Anthony DiNatale","raw_affiliation_strings":[],"raw_orcid":"https://orcid.org/0000-0003-3221-7506","affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5015246723","display_name":"Asurayya Worrede","orcid":"https://orcid.org/0000-0003-2013-0112","observed_orcids":["https://orcid.org/0000-0003-2013-0112"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Asurayya Worrede","raw_affiliation_strings":[],"raw_orcid":"https://orcid.org/0000-0003-2013-0112","affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5024187967","display_name":"Waleed Iqbal","orcid":"https://orcid.org/0000-0002-1478-2969","observed_orcids":["https://orcid.org/0000-0002-1478-2969"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Waleed Iqbal","raw_affiliation_strings":[],"raw_orcid":"https://orcid.org/0000-0002-1478-2969","affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5020767736","display_name":"Michael Marchioli","orcid":"https://orcid.org/0000-0001-9572-5263","observed_orcids":["https://orcid.org/0000-0001-9572-5263"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Michael Marchioli","raw_affiliation_strings":[],"raw_orcid":"https://orcid.org/0000-0001-9572-5263","affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5026604312","display_name":"Allison Toth","orcid":"https://orcid.org/0000-0003-2919-7655","observed_orcids":["https://orcid.org/0000-0003-2919-7655"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Allison Toth","raw_affiliation_strings":[],"raw_orcid":"https://orcid.org/0000-0003-2919-7655","affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5039517115","display_name":"Martin Sj\u00f6str\u00f6m","orcid":"https://orcid.org/0000-0002-2629-9966","observed_orcids":["https://orcid.org/0000-0002-2629-9966"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Martin Sj\u00f6str\u00f6m","raw_affiliation_strings":[],"raw_orcid":"https://orcid.org/0000-0002-2629-9966","affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5077362015","display_name":"Xiaolin Zhu","orcid":"https://orcid.org/0000-0002-3221-595X","observed_orcids":["https://orcid.org/0000-0002-3221-595X"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Xiaolin Zhu","raw_affiliation_strings":[],"raw_orcid":"https://orcid.org/0000-0002-3221-595X","affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5018745405","display_name":"Eva Corey","orcid":"https://orcid.org/0000-0002-9244-3807","observed_orcids":["https://orcid.org/0000-0002-9244-3807"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Eva Corey","raw_affiliation_strings":[],"raw_orcid":"https://orcid.org/0000-0002-9244-3807","affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5020006331","display_name":"Felix Yi-Chung Feng","orcid":"https://orcid.org/0000-0002-0963-7687","observed_orcids":["https://orcid.org/0000-0002-0963-7687","https://orcid.org/0000-0001-9756-4037"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Felix Y. Feng","raw_affiliation_strings":[],"raw_orcid":"https://orcid.org/0000-0002-0963-7687","affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5010106597","display_name":"Wanding Zhou","orcid":"https://orcid.org/0000-0001-9126-1932","observed_orcids":["https://orcid.org/0000-0001-9126-1932"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Wanding Zhou","raw_affiliation_strings":[],"raw_orcid":"https://orcid.org/0000-0001-9126-1932","affiliations":[]},{"author_position":"last","author":{"id":"https://openalex.org/A5021021049","display_name":"Alessandro Fatatis","orcid":"https://orcid.org/0000-0003-3945-8513","observed_orcids":["https://orcid.org/0000-0003-3945-8513"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Alessandro Fatatis","raw_affiliation_strings":[],"raw_orcid":"https://orcid.org/0000-0003-3945-8513","affiliations":[]}],"institutions":[],"countries_distinct_count":0,"institutions_distinct_count":0,"corresponding_author_ids":[],"corresponding_institution_ids":[],"apc_list":null,"apc_paid":null,"fwci":null,"has_fulltext":false,"cited_by_count":0,"citation_normalized_percentile":null,"cited_by_percentile_year":null,"biblio":{"volume":null,"issue":null,"first_page":null,"last_page":null},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10543","display_name":"Prostate Cancer Treatment and Research","score":1.0,"subfield":{"id":"https://openalex.org/subfields/1306","display_name":"Cancer Research"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T10543","display_name":"Prostate Cancer Treatment and Research","score":1.0,"subfield":{"id":"https://openalex.org/subfields/1306","display_name":"Cancer Research"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T11221","display_name":"Bone health and treatments","score":0.0,"subfield":{"id":"https://openalex.org/subfields/2730","display_name":"Oncology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10124","display_name":"Prostate Cancer Diagnosis and Treatment","score":0.0,"subfield":{"id":"https://openalex.org/subfields/2748","display_name":"Urology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/interleukin-1beta","display_name":"IL-1\u03b2","score":0.8190000057220459},{"id":"https://openalex.org/keywords/androgen-receptor","display_name":"androgen receptor","score":0.9810000061988831},{"id":"https://openalex.org/keywords/prostate-cancer","display_name":"prostate cancer","score":0.781000018119812},{"id":"https://openalex.org/keywords/bone-metastases","display_name":"bone metastasis","score":0.9990000128746033},{"id":"https://openalex.org/keywords/enzalutamide","display_name":"enzalutamide","score":0.9959999918937683},{"id":"https://openalex.org/keywords/c4-2b-cells","display_name":"C4-2B cells","score":0.8980000019073486},{"id":"https://openalex.org/keywords/hormone-deprivation","display_name":"hormone deprivation","score":0.6539999842643738},{"id":"https://openalex.org/keywords/androgen-deprivation-therapy","display_name":"androgen deprivation therapy","score":0.7350000143051147}],"concepts":[{"id":"https://openalex.org/C2776551883","wikidata":"https://www.wikidata.org/wiki/Q1996756","display_name":"Enzalutamide","level":5,"score":0.9361963868141174},{"id":"https://openalex.org/C2780192828","wikidata":"https://www.wikidata.org/wiki/Q181257","display_name":"Prostate cancer","level":3,"score":0.7945472002029419},{"id":"https://openalex.org/C61367390","wikidata":"https://www.wikidata.org/wiki/Q416601","display_name":"Androgen receptor","level":4,"score":0.6744000911712646},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.5751550793647766},{"id":"https://openalex.org/C134018914","wikidata":"https://www.wikidata.org/wiki/Q162606","display_name":"Endocrinology","level":1,"score":0.5448850989341736},{"id":"https://openalex.org/C2777783956","wikidata":"https://www.wikidata.org/wiki/Q848085","display_name":"Bone metastasis","level":4,"score":0.5179725885391235},{"id":"https://openalex.org/C502942594","wikidata":"https://www.wikidata.org/wiki/Q3421914","display_name":"Cancer research","level":1,"score":0.48094266653060913},{"id":"https://openalex.org/C2779013556","wikidata":"https://www.wikidata.org/wiki/Q181876","display_name":"Metastasis","level":3,"score":0.4743413031101227},{"id":"https://openalex.org/C2777911890","wikidata":"https://www.wikidata.org/wiki/Q62614","display_name":"Androgen","level":3,"score":0.47104907035827637},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.4646104872226715},{"id":"https://openalex.org/C2776235491","wikidata":"https://www.wikidata.org/wiki/Q9625","display_name":"Prostate","level":3,"score":0.4560433030128479},{"id":"https://openalex.org/C170493617","wikidata":"https://www.wikidata.org/wiki/Q208467","display_name":"Receptor","level":2,"score":0.4454612135887146},{"id":"https://openalex.org/C2777899217","wikidata":"https://www.wikidata.org/wiki/Q4759439","display_name":"Androgen deprivation therapy","level":4,"score":0.4450574815273285},{"id":"https://openalex.org/C185592680","wikidata":"https://www.wikidata.org/wiki/Q2329","display_name":"Chemistry","level":0,"score":0.35146236419677734},{"id":"https://openalex.org/C121608353","wikidata":"https://www.wikidata.org/wiki/Q12078","display_name":"Cancer","level":2,"score":0.345216304063797},{"id":"https://openalex.org/C71315377","wikidata":"https://www.wikidata.org/wiki/Q11364","display_name":"Hormone","level":2,"score":0.3406781554222107}],"mesh":[],"locations_count":2,"locations":[{"id":"doi:10.1158/2767-9764.22361308","doi":"https://doi.org/10.1158/2767-9764.22361308","is_oa":true,"landing_page_url":"http://dx.doi.org/10.1158/2767-9764.22361308","pdf_url":null,"source":null,"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"acceptedVersion","is_accepted":true,"is_published":false,"raw_source_name":"American Association for Cancer Research","raw_type":"posted-content"},{"id":"doi:10.1158/2767-9764.22361308.v1","doi":"https://doi.org/10.1158/2767-9764.22361308.v1","is_oa":true,"landing_page_url":"https://doi.org/10.1158/2767-9764.22361308.v1","pdf_url":null,"source":null,"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"acceptedVersion","is_accepted":true,"is_published":false,"raw_source_name":"American Association for Cancer Research","raw_type":"posted-content"}],"best_oa_location":{"id":"doi:10.1158/2767-9764.22361308","doi":"https://doi.org/10.1158/2767-9764.22361308","is_oa":true,"landing_page_url":"http://dx.doi.org/10.1158/2767-9764.22361308","pdf_url":null,"source":null,"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"acceptedVersion","is_accepted":true,"is_published":false,"raw_source_name":"American Association for Cancer Research","raw_type":"posted-content"},"sustainable_development_goals":[{"score":0.9789000153541565,"id":"https://metadata.un.org/sdg/3","display_name":"Good health and well-being"}],"study_designs":[],"awards":[],"funders":[],"has_content":{"grobid_xml":false,"pdf":false},"content_urls":null,"referenced_works_count":0,"referenced_works":[],"related_works":["https://openalex.org/W4361272126","https://openalex.org/W4361272119","https://openalex.org/W4308710249","https://openalex.org/W4361272036","https://openalex.org/W4361279457","https://openalex.org/W2565954064","https://openalex.org/W4361260790","https://openalex.org/W2155710121","https://openalex.org/W4409691544","https://openalex.org/W4361272227"],"abstract_inverted_index":{"C4-2B":[0],"cells":[1],"exposed":[2],"to":[3,30],"Enzalutamide":[4],"show":[5],"a":[6,20,25],"dose-dependent(a)":[7],"and":[8],"time-":[9],"dependent":[10],"increase":[11],"in":[12,24],"IL-1\u03b2":[13,28],"expression":[14,29],"(b).":[15],"Removal":[16],"of":[17,27],"enzalutamide":[18],"after":[19],"15-day":[21,40],"treatment":[22],"resulted":[23],"return":[26],"control":[31],"(undetectable)":[32],"levels":[33],"(c).":[34],"Same":[35],"results":[36],"were":[37],"obtained":[38],"with":[39],"hormone-deprivation":[41],"followed":[42],"by":[43],"DHT":[44],"re-addition":[45],"(d).":[46]},"counts_by_year":[],"updated_date":"2026-11-04T10:54:05.112534","created_date":"2023-03-31T00:00:00"}