{"id":"https://openalex.org/W4361269734","doi":"https://doi.org/10.1021/acs.orglett.3c00809","title":"I(III)-Mediated Arene C\u2013H Amination Using (Hetero)Aryl Nucleophiles","display_name":"I(III)-Mediated Arene C\u2013H Amination Using (Hetero)Aryl Nucleophiles","publication_year":2023,"publication_date":"2023-03-30","ids":{"openalex":"https://openalex.org/W4361269734","doi":"https://doi.org/10.1021/acs.orglett.3c00809","pmid":"https://pubmed.ncbi.nlm.nih.gov/36995156"},"language":"en","primary_location":{"id":"doi:10.1021/acs.orglett.3c00809","doi":"https://doi.org/10.1021/acs.orglett.3c00809","is_oa":false,"landing_page_url":"https://doi.org/10.1021/acs.orglett.3c00809","pdf_url":null,"source":{"id":"https://openalex.org/S201989124","display_name":"Organic Letters","issn_l":"1523-7052","issn":["1523-7052","1523-7060"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-a","jufo-2","ki-jl-2","medline","norway-2","poland-140","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320006","host_organization_name":"American Chemical Society","host_organization_lineage":["https://openalex.org/P4310320006"],"host_organization_lineage_names":["American Chemical Society"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Organic Letters","raw_type":"journal-article"},"volume":null,"type":"article","indexed_in":["crossref","pubmed"],"open_access":{"is_oa":true,"oa_status":"green","oa_url":"https://chemrxiv.org/engage/api-gateway/chemrxiv/assets/orp/resource/item/63da8b6f01ecc690f91be0e3/original/i-iii-mediated-arene-c-h-amination-using-hetero-aryl-nucleophiles.pdf","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5019137513","display_name":"Bill J. Motsch","orcid":"https://orcid.org/0000-0002-7322-2662","observed_orcids":["https://orcid.org/0000-0002-7322-2662"]},"institutions":[{"id":"https://openalex.org/I84392919","display_name":"Temple University","ror":"https://ror.org/00kx1jb78","country_code":"US","type":"education","lineage":["https://openalex.org/I84392919"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Bill J. Motsch","raw_affiliation_strings":["Department of Chemistry, Temple University, 1901 North 13th Street, Philadelphia, Pennsylvania 19122, United States"],"raw_orcid":"https://orcid.org/0000-0002-7322-2662","affiliations":[{"raw_affiliation_string":"Department of Chemistry, Temple University, 1901 North 13th Street, Philadelphia, Pennsylvania 19122, United States","institution_ids":["https://openalex.org/I84392919"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5051181099","display_name":"Jasjit Y. Kaur","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I84392919","display_name":"Temple University","ror":"https://ror.org/00kx1jb78","country_code":"US","type":"education","lineage":["https://openalex.org/I84392919"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Jasjit Y. Kaur","raw_affiliation_strings":["Department of Chemistry, Temple University, 1901 North 13th Street, Philadelphia, Pennsylvania 19122, United States"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Chemistry, Temple University, 1901 North 13th Street, Philadelphia, Pennsylvania 19122, United States","institution_ids":["https://openalex.org/I84392919"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5048276074","display_name":"Sarah E. Wengryniuk","orcid":"https://orcid.org/0000-0002-4797-0181","observed_orcids":["https://orcid.org/0000-0002-4797-0181"]},"institutions":[{"id":"https://openalex.org/I84392919","display_name":"Temple University","ror":"https://ror.org/00kx1jb78","country_code":"US","type":"education","lineage":["https://openalex.org/I84392919"]}],"countries":["US"],"is_corresponding":true,"raw_author_name":"Sarah E. Wengryniuk","raw_affiliation_strings":["Department of Chemistry, Temple University, 1901 North 13th Street, Philadelphia, Pennsylvania 19122, United States"],"raw_orcid":"https://orcid.org/0000-0002-4797-0181","affiliations":[{"raw_affiliation_string":"Department of Chemistry, Temple University, 1901 North 13th Street, Philadelphia, Pennsylvania 19122, United States","institution_ids":["https://openalex.org/I84392919"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":1,"corresponding_author_ids":["https://openalex.org/A5048276074"],"corresponding_institution_ids":["https://openalex.org/I84392919"],"apc_list":{"value":5000,"currency":"USD","value_usd":5000},"apc_paid":null,"fwci":1.2296,"has_fulltext":false,"cited_by_count":12,"citation_normalized_percentile":{"value":0.74112082,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":94,"max":98},"biblio":{"volume":"25","issue":"14","first_page":"2548","last_page":"2553"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T11989","display_name":"Oxidative Organic Chemistry Reactions","score":0.8353999853134155,"subfield":{"id":"https://openalex.org/subfields/1605","display_name":"Organic Chemistry"},"field":{"id":"https://openalex.org/fields/16","display_name":"Chemistry"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},"topics":[{"id":"https://openalex.org/T11989","display_name":"Oxidative Organic Chemistry Reactions","score":0.8353999853134155,"subfield":{"id":"https://openalex.org/subfields/1605","display_name":"Organic Chemistry"},"field":{"id":"https://openalex.org/fields/16","display_name":"Chemistry"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},{"id":"https://openalex.org/T10354","display_name":"Catalytic C\u2013H Functionalization Methods","score":0.05689999833703041,"subfield":{"id":"https://openalex.org/subfields/1605","display_name":"Organic Chemistry"},"field":{"id":"https://openalex.org/fields/16","display_name":"Chemistry"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},{"id":"https://openalex.org/T10701","display_name":"Radical Photochemical Reactions","score":0.05209999904036522,"subfield":{"id":"https://openalex.org/subfields/1605","display_name":"Organic Chemistry"},"field":{"id":"https://openalex.org/fields/16","display_name":"Chemistry"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/c-h-amination","display_name":"C\u2013H amination","score":0.828000009059906},{"id":"https://openalex.org/keywords/aromatic-hydrocarbons","display_name":"aromatic hydrocarbons","score":0.953000009059906},{"id":"https://openalex.org/keywords/nitrogen-containing-heterocycles","display_name":"nitrogen heterocycles","score":0.7080000042915344},{"id":"https://openalex.org/keywords/amine-nucleophiles","display_name":"amine nucleophiles","score":0.8190000057220459},{"id":"https://openalex.org/keywords/metal-free-oxidation","display_name":"metal-free oxidation","score":0.7979999780654907}],"concepts":[{"id":"https://openalex.org/C185592680","wikidata":"https://www.wikidata.org/wiki/Q2329","display_name":"Chemistry","level":0,"score":0.9761947393417358},{"id":"https://openalex.org/C178907741","wikidata":"https://www.wikidata.org/wiki/Q745930","display_name":"Nucleophile","level":3,"score":0.9108060598373413},{"id":"https://openalex.org/C198503264","wikidata":"https://www.wikidata.org/wiki/Q471635","display_name":"Amination","level":3,"score":0.8980680108070374},{"id":"https://openalex.org/C2777221202","wikidata":"https://www.wikidata.org/wiki/Q2518436","display_name":"Pyridinium","level":2,"score":0.777935266494751},{"id":"https://openalex.org/C131779359","wikidata":"https://www.wikidata.org/wiki/Q471875","display_name":"Amine gas treating","level":2,"score":0.7052922248840332},{"id":"https://openalex.org/C40875361","wikidata":"https://www.wikidata.org/wiki/Q2356542","display_name":"Reagent","level":2,"score":0.6993280053138733},{"id":"https://openalex.org/C2781076698","wikidata":"https://www.wikidata.org/wiki/Q718074","display_name":"Aryl","level":3,"score":0.6623246073722839},{"id":"https://openalex.org/C21951064","wikidata":"https://www.wikidata.org/wiki/Q899212","display_name":"Combinatorial chemistry","level":1,"score":0.491659939289093},{"id":"https://openalex.org/C155647269","wikidata":"https://www.wikidata.org/wiki/Q243455","display_name":"Medicinal chemistry","level":1,"score":0.45347124338150024},{"id":"https://openalex.org/C178790620","wikidata":"https://www.wikidata.org/wiki/Q11351","display_name":"Organic chemistry","level":1,"score":0.428072065114975},{"id":"https://openalex.org/C161790260","wikidata":"https://www.wikidata.org/wiki/Q82264","display_name":"Catalysis","level":2,"score":0.10991233587265015},{"id":"https://openalex.org/C2780263894","wikidata":"https://www.wikidata.org/wiki/Q335268","display_name":"Alkyl","level":2,"score":0.0}],"mesh":[],"locations_count":3,"locations":[{"id":"doi:10.1021/acs.orglett.3c00809","doi":"https://doi.org/10.1021/acs.orglett.3c00809","is_oa":false,"landing_page_url":"https://doi.org/10.1021/acs.orglett.3c00809","pdf_url":null,"source":{"id":"https://openalex.org/S201989124","display_name":"Organic Letters","issn_l":"1523-7052","issn":["1523-7052","1523-7060"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-a","jufo-2","ki-jl-2","medline","norway-2","poland-140","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320006","host_organization_name":"American Chemical Society","host_organization_lineage":["https://openalex.org/P4310320006"],"host_organization_lineage_names":["American Chemical Society"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Organic Letters","raw_type":"journal-article"},{"id":"doi:10.26434/chemrxiv-2023-r344r","doi":"https://doi.org/10.26434/chemrxiv-2023-r344r","is_oa":true,"landing_page_url":"https://doi.org/10.26434/chemrxiv-2023-r344r","pdf_url":"https://chemrxiv.org/engage/api-gateway/chemrxiv/assets/orp/resource/item/63da8b6f01ecc690f91be0e3/original/i-iii-mediated-arene-c-h-amination-using-hetero-aryl-nucleophiles.pdf","source":{"id":"https://openalex.org/S4393918830","display_name":"ChemRxiv","issn_l":"2573-2293","issn":["2573-2293"],"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by-nc-nd","license_id":"https://openalex.org/licenses/cc-by-nc-nd","version":"acceptedVersion","is_accepted":true,"is_published":false,"raw_source_name":null,"raw_type":"posted-content"},{"id":"pmid:36995156","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/36995156","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Organic letters","raw_type":"Journal Article"}],"best_oa_location":{"id":"doi:10.26434/chemrxiv-2023-r344r","doi":"https://doi.org/10.26434/chemrxiv-2023-r344r","is_oa":true,"landing_page_url":"https://doi.org/10.26434/chemrxiv-2023-r344r","pdf_url":"https://chemrxiv.org/engage/api-gateway/chemrxiv/assets/orp/resource/item/63da8b6f01ecc690f91be0e3/original/i-iii-mediated-arene-c-h-amination-using-hetero-aryl-nucleophiles.pdf","source":{"id":"https://openalex.org/S4393918830","display_name":"ChemRxiv","issn_l":"2573-2293","issn":["2573-2293"],"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by-nc-nd","license_id":"https://openalex.org/licenses/cc-by-nc-nd","version":"acceptedVersion","is_accepted":true,"is_published":false,"raw_source_name":null,"raw_type":"posted-content"},"sustainable_development_goals":[],"sustainable_development_goals_aurora":[{"score":0.6800000071525574,"display_name":"Clean water and sanitation","id":"https://metadata.un.org/sdg/6"}],"study_designs":[],"awards":[{"id":"https://openalex.org/G1849836450","display_name":"CAREER: Novel Synthetic Applications of Poly(cationic) lambda-3 Iodanes","funder_award_id":"1752244","funder_id":"https://openalex.org/F4320306076","funder_display_name":"National Science Foundation"},{"id":"https://openalex.org/G3221074797","display_name":null,"funder_award_id":"1752244","funder_id":"https://openalex.org/F4320337393","funder_display_name":"Division of Chemistry"},{"id":"https://openalex.org/G3951481505","display_name":"Oxidative Strategies for the Synthesis of N-Alkyl and N-Aryl Pyridinium Salts","funder_award_id":"2154640","funder_id":"https://openalex.org/F4320306076","funder_display_name":"National Science Foundation"},{"id":"https://openalex.org/G5308231833","display_name":null,"funder_award_id":"CAREER 1752244","funder_id":"https://openalex.org/F4320337393","funder_display_name":"Division of Chemistry"},{"id":"https://openalex.org/G5986892838","display_name":null,"funder_award_id":"CAREER","funder_id":"https://openalex.org/F4320337393","funder_display_name":"Division of Chemistry"},{"id":"https://openalex.org/G6671297155","display_name":null,"funder_award_id":"CAREER","funder_id":"https://openalex.org/F4320306076","funder_display_name":"National Science Foundation"},{"id":"https://openalex.org/G6792622186","display_name":null,"funder_award_id":"CHE 2154640","funder_id":"https://openalex.org/F4320337393","funder_display_name":"Division of Chemistry"}],"funders":[{"id":"https://openalex.org/F4320306076","display_name":"National Science Foundation","ror":"https://ror.org/021nxhr62"},{"id":"https://openalex.org/F4320337393","display_name":"Division of Chemistry","ror":"https://ror.org/01ar8dr59"}],"has_content":{"pdf":true,"grobid_xml":true},"content_urls":{"pdf":"https://content.openalex.org/works/W4361269734.pdf","grobid_xml":"https://content.openalex.org/works/W4361269734.grobid-xml"},"referenced_works_count":45,"referenced_works":["https://openalex.org/W1988213097","https://openalex.org/W1994787858","https://openalex.org/W2001920359","https://openalex.org/W2012867612","https://openalex.org/W2020086870","https://openalex.org/W2032247899","https://openalex.org/W2068749447","https://openalex.org/W2075696778","https://openalex.org/W2077782725","https://openalex.org/W2155577396","https://openalex.org/W2168916022","https://openalex.org/W2236745200","https://openalex.org/W2265362920","https://openalex.org/W2312941087","https://openalex.org/W2322296010","https://openalex.org/W2322822694","https://openalex.org/W2324576202","https://openalex.org/W2325072690","https://openalex.org/W2330703002","https://openalex.org/W2473025600","https://openalex.org/W2542844034","https://openalex.org/W2578593053","https://openalex.org/W2742947069","https://openalex.org/W2765487959","https://openalex.org/W2765512778","https://openalex.org/W2787519598","https://openalex.org/W2790594002","https://openalex.org/W2794020757","https://openalex.org/W2900026328","https://openalex.org/W2900069206","https://openalex.org/W2952363360","https://openalex.org/W2958110245","https://openalex.org/W2979672031","https://openalex.org/W3012751933","https://openalex.org/W3081524402","https://openalex.org/W3130530671","https://openalex.org/W3151211230","https://openalex.org/W3153499610","https://openalex.org/W3174644572","https://openalex.org/W3197693574","https://openalex.org/W3206942590","https://openalex.org/W4290644227","https://openalex.org/W4292426458","https://openalex.org/W4295760892","https://openalex.org/W4361269734"],"related_works":["https://openalex.org/W3133580746","https://openalex.org/W2168973975","https://openalex.org/W2949924169","https://openalex.org/W2404416964","https://openalex.org/W4401951293","https://openalex.org/W2012867612","https://openalex.org/W2078611209","https://openalex.org/W4304117499","https://openalex.org/W3185768845","https://openalex.org/W3013064848"],"abstract_inverted_index":{"Herein,":[0],"we":[1],"report":[2],"the":[3,30,50,59],"metal-free":[4],"oxidative":[5],"C\u2013H":[6],"amination":[7],"of":[8,52,58],"arenes":[9],"via":[10],"a":[11],"\u201cheterocyclic":[12],"group":[13],"transfer\u201d":[14],"reaction":[15,41],"from":[16],"an":[17,53],"I(III)":[18],"N":[19,32],"-HVI":[20],"reagent.":[21],"N-Heterocycles":[22],"serve":[23],"as":[24],"oxidatively":[25],"masked":[26],"amine":[27,66],"nucleophiles,":[28],"and":[29,46],"resulting":[31,60],"-arylpyridinium":[33],"salts":[34,62],"are":[35,68],"inert":[36],"to":[37,63],"further":[38],"oxidation.":[39],"The":[40],"proceeds":[42],"under":[43],"mild":[44],"conditions,":[45],"mechanistic":[47],"studies":[48],"indicate":[49],"intermediacy":[51],"arene":[54],"radical":[55],"cation.":[56],"Derivatizations":[57],"pyridinium":[61],"diverse":[64],"aryl":[65],"scaffolds":[67],"demonstrated.":[69]},"counts_by_year":[{"year":2026,"cited_by_count":2},{"year":2025,"cited_by_count":2},{"year":2024,"cited_by_count":5},{"year":2023,"cited_by_count":3}],"updated_date":"2026-10-14T16:39:01.820549","created_date":"2023-03-31T00:00:00"}