{"id":"https://openalex.org/W4361237946","doi":"https://doi.org/10.1158/0008-5472.22407098","title":"Supplementary Figure 1 from Modification of Helicobacter pylori Peptidoglycan Enhances NOD1 Activation and Promotes Cancer of the Stomach","display_name":"Supplementary Figure 1 from Modification of Helicobacter pylori Peptidoglycan Enhances NOD1 Activation and Promotes Cancer of the Stomach","publication_year":2023,"publication_date":"2023-03-30","ids":{"openalex":"https://openalex.org/W4361237946","doi":"https://doi.org/10.1158/0008-5472.22407098"},"language":"en","primary_location":{"id":"doi:10.1158/0008-5472.22407098","doi":"https://doi.org/10.1158/0008-5472.22407098","is_oa":true,"landing_page_url":"http://dx.doi.org/10.1158/0008-5472.22407098","pdf_url":null,"source":null,"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"acceptedVersion","is_accepted":true,"is_published":false,"raw_source_name":"American Association for Cancer Research","raw_type":"posted-content"},"volume":null,"type":"supplementary-materials","is_traditional":false,"indexed_in":["crossref"],"open_access":{"is_oa":true,"oa_status":"gold","oa_url":"http://dx.doi.org/10.1158/0008-5472.22407098","any_repository_has_fulltext":null},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5113869503","display_name":"Giovanni Su\u00e1rez","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Giovanni Suarez","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5085882005","display_name":"Judith Romero\u2013Gallo","orcid":"https://orcid.org/0000-0002-6023-7793","observed_orcids":["https://orcid.org/0000-0002-6023-7793"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Judith Romero-Gallo","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5001458889","display_name":"M. Blanca Piazuelo","orcid":"https://orcid.org/0000-0002-0000-1324","observed_orcids":["https://orcid.org/0000-0002-0000-1324"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"M. Blanca Piazuelo","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":null,"display_name":"Ge Wang","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Ge Wang","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5076187405","display_name":"Robert J. Maier","orcid":"https://orcid.org/0000-0002-1281-2554","observed_orcids":["https://orcid.org/0000-0002-1281-2554"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Robert J. Maier","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5056139963","display_name":"Lennart S. Forsberg","orcid":"https://orcid.org/0000-0002-6905-2760","observed_orcids":["https://orcid.org/0000-0002-6905-2760"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Lennart S. Forsberg","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5073577112","display_name":"Parastoo Azadi","orcid":"https://orcid.org/0000-0002-6166-9432","observed_orcids":["https://orcid.org/0000-0002-6166-9432"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Parastoo Azadi","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5041852524","display_name":"Mart\u00edn Alonso G\u00f3mez Zuleta","orcid":"https://orcid.org/0000-0002-2377-6544","observed_orcids":["https://orcid.org/0000-0002-2377-6544"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Martin A. Gomez","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5112869712","display_name":"Pelayo Correa","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Pelayo Correa","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"last","author":{"id":"https://openalex.org/A5047989998","display_name":"Richard M. Peek","orcid":"https://orcid.org/0000-0002-4836-5960","observed_orcids":["https://orcid.org/0000-0002-4836-5960"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Richard M. Peek","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]}],"institutions":[],"countries_distinct_count":0,"institutions_distinct_count":0,"corresponding_author_ids":[],"corresponding_institution_ids":[],"apc_list":null,"apc_paid":null,"fwci":null,"has_fulltext":false,"cited_by_count":0,"citation_normalized_percentile":null,"cited_by_percentile_year":null,"biblio":{"volume":null,"issue":null,"first_page":null,"last_page":null},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10276","display_name":"Helicobacter pylori-related gastroenterology studies","score":0.9984999895095825,"subfield":{"id":"https://openalex.org/subfields/2715","display_name":"Gastroenterology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T10276","display_name":"Helicobacter pylori-related gastroenterology studies","score":0.9984999895095825,"subfield":{"id":"https://openalex.org/subfields/2715","display_name":"Gastroenterology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10371","display_name":"Immune Response and Inflammation","score":0.0005000000237487257,"subfield":{"id":"https://openalex.org/subfields/2403","display_name":"Immunology"},"field":{"id":"https://openalex.org/fields/24","display_name":"Immunology and Microbiology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10696","display_name":"Gastric Cancer Management and Outcomes","score":9.999999747378752e-05,"subfield":{"id":"https://openalex.org/subfields/2730","display_name":"Oncology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/helicobacter-pylori","display_name":"Helicobacter pylori","score":0.9990000128746033},{"id":"https://openalex.org/keywords/peptidoglycan-modification","display_name":"peptidoglycan modification","score":0.9539999961853027},{"id":"https://openalex.org/keywords/gastric-cancer","display_name":"gastric cancer","score":0.8379999995231628},{"id":"https://openalex.org/keywords/peptidoglycan-synthesis","display_name":"peptidoglycan biosynthesis","score":0.718999981880188},{"id":"https://openalex.org/keywords/isogenic-mutants","display_name":"isogenic mutants","score":0.5910000205039978},{"id":"https://openalex.org/keywords/complementation","display_name":"complementation","score":0.8450000286102295}],"concepts":[{"id":"https://openalex.org/C2776634448","wikidata":"https://www.wikidata.org/wiki/Q206920","display_name":"Peptidoglycan","level":3,"score":0.7791671752929688},{"id":"https://openalex.org/C2776409635","wikidata":"https://www.wikidata.org/wiki/Q180556","display_name":"Helicobacter pylori","level":2,"score":0.7536414265632629},{"id":"https://openalex.org/C143065580","wikidata":"https://www.wikidata.org/wiki/Q3285695","display_name":"Mutant","level":3,"score":0.7175576090812683},{"id":"https://openalex.org/C2776415932","wikidata":"https://www.wikidata.org/wiki/Q48743","display_name":"Western blot","level":3,"score":0.6343420147895813},{"id":"https://openalex.org/C2777291061","wikidata":"https://www.wikidata.org/wiki/Q18035347","display_name":"NOD1","level":5,"score":0.6106230616569519},{"id":"https://openalex.org/C153911025","wikidata":"https://www.wikidata.org/wiki/Q7202","display_name":"Molecular biology","level":1,"score":0.48309922218322754},{"id":"https://openalex.org/C2778022156","wikidata":"https://www.wikidata.org/wiki/Q576145","display_name":"Strain (injury)","level":2,"score":0.42451009154319763},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.38566386699676514},{"id":"https://openalex.org/C185592680","wikidata":"https://www.wikidata.org/wiki/Q2329","display_name":"Chemistry","level":0,"score":0.3767879605293274},{"id":"https://openalex.org/C54355233","wikidata":"https://www.wikidata.org/wiki/Q7162","display_name":"Genetics","level":1,"score":0.25607824325561523},{"id":"https://openalex.org/C523546767","wikidata":"https://www.wikidata.org/wiki/Q10876","display_name":"Bacteria","level":2,"score":0.2429690957069397},{"id":"https://openalex.org/C104317684","wikidata":"https://www.wikidata.org/wiki/Q7187","display_name":"Gene","level":2,"score":0.22755280137062073},{"id":"https://openalex.org/C105702510","wikidata":"https://www.wikidata.org/wiki/Q514","display_name":"Anatomy","level":1,"score":0.10169091820716858},{"id":"https://openalex.org/C170493617","wikidata":"https://www.wikidata.org/wiki/Q208467","display_name":"Receptor","level":2,"score":0.06454560160636902},{"id":"https://openalex.org/C136449434","wikidata":"https://www.wikidata.org/wiki/Q428253","display_name":"Innate immune system","level":3,"score":0.0},{"id":"https://openalex.org/C7573103","wikidata":"https://www.wikidata.org/wiki/Q416481","display_name":"NOD2","level":4,"score":0.0}],"mesh":[],"locations_count":2,"locations":[{"id":"doi:10.1158/0008-5472.22407098","doi":"https://doi.org/10.1158/0008-5472.22407098","is_oa":true,"landing_page_url":"http://dx.doi.org/10.1158/0008-5472.22407098","pdf_url":null,"source":null,"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"acceptedVersion","is_accepted":true,"is_published":false,"raw_source_name":"American Association for Cancer Research","raw_type":"posted-content"},{"id":"doi:10.1158/0008-5472.22407098.v1","doi":"https://doi.org/10.1158/0008-5472.22407098.v1","is_oa":true,"landing_page_url":"https://doi.org/10.1158/0008-5472.22407098.v1","pdf_url":null,"source":null,"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"acceptedVersion","is_accepted":true,"is_published":false,"raw_source_name":"American Association for Cancer Research","raw_type":"posted-content"}],"best_oa_location":{"id":"doi:10.1158/0008-5472.22407098","doi":"https://doi.org/10.1158/0008-5472.22407098","is_oa":true,"landing_page_url":"http://dx.doi.org/10.1158/0008-5472.22407098","pdf_url":null,"source":null,"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"acceptedVersion","is_accepted":true,"is_published":false,"raw_source_name":"American Association for Cancer Research","raw_type":"posted-content"},"sustainable_development_goals":[{"id":"https://metadata.un.org/sdg/3","display_name":"Good health and well-being","score":0.8560000061988831}],"study_designs":[],"awards":[],"funders":[],"has_content":{"grobid_xml":false,"pdf":false},"content_urls":null,"referenced_works_count":0,"referenced_works":[],"related_works":["https://openalex.org/W2047184114","https://openalex.org/W4361804914","https://openalex.org/W1645127799","https://openalex.org/W1116514882","https://openalex.org/W1941917110","https://openalex.org/W1883003174","https://openalex.org/W2067335574","https://openalex.org/W2140144249","https://openalex.org/W1225777587","https://openalex.org/W2070559377"],"abstract_inverted_index":{"Supplemental":[0],"Figure":[1],"1.":[2],"(A)":[3],"Western":[4],"blot":[5],"and":[6,22,34,57,64],"densitometric":[7],"analysis":[8],"for":[9,52],"expression":[10],"of":[11,62,83],"PgdA":[12,63],"in":[13],"H.":[14,43],"pylori":[15,44],"wild":[16],"type":[17],"strains":[18],"B128":[19],"(lane":[20,24,32],"1)":[21],"7.13":[23,27,36],"2),":[25],"a":[26,35,49],"pgdA-":[28],"isogenic":[29],"mutant":[30,39],"strain":[31],"3)":[33],"pgdA":[37],"complemented":[38],"(pgdA/c;":[40],"lane":[41],"4).":[42],"DnaJ":[45,65],"was":[46,66],"used":[47],"as":[48,73],"loading":[50],"control":[51],"bacterial":[53],"protein":[54],"(Bottom":[55],"panel)":[56],"the":[58,84],"ratio":[59],"between":[60],"levels":[61],"calculated":[67],"(top":[68],"panel).":[69],"Data":[70],"are":[71],"represented":[72],"mean{plus":[74],"minus}SEM":[75],"from":[76],"2":[77],"independent":[78],"experiments.":[79],"(B)":[80],"Putative":[81],"structure":[82],"MP1470":[85],"ion.":[86]},"counts_by_year":[],"updated_date":"2026-11-04T10:54:05.112534","created_date":"2023-03-31T00:00:00"}