{"id":"https://openalex.org/W4361237385","doi":"https://doi.org/10.1158/0008-5472.22410549","title":"Supplementary Figure S4 from Pharmacological Targeting of the Histone Chaperone Complex FACT Preferentially Eliminates Glioblastoma Stem Cells and Prolongs Survival in Preclinical Models","display_name":"Supplementary Figure S4 from Pharmacological Targeting of the Histone Chaperone Complex FACT Preferentially Eliminates Glioblastoma Stem Cells and Prolongs Survival in Preclinical Models","publication_year":2023,"publication_date":"2023-03-31","ids":{"openalex":"https://openalex.org/W4361237385","doi":"https://doi.org/10.1158/0008-5472.22410549"},"language":"en","primary_location":{"id":"doi:10.1158/0008-5472.22410549","doi":"https://doi.org/10.1158/0008-5472.22410549","is_oa":true,"landing_page_url":"http://dx.doi.org/10.1158/0008-5472.22410549","pdf_url":null,"source":null,"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"acceptedVersion","is_accepted":true,"is_published":false,"raw_source_name":"American Association for Cancer Research","raw_type":"posted-content"},"volume":null,"type":"supplementary-materials","indexed_in":["crossref"],"open_access":{"is_oa":true,"oa_status":"gold","oa_url":"http://dx.doi.org/10.1158/0008-5472.22410549","any_repository_has_fulltext":null},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5058391665","display_name":"Josephine Kam Tai Dermawan","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Josephine Kam Tai Dermawan","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5013023933","display_name":"Masahiro Hitomi","orcid":"https://orcid.org/0000-0002-0937-6640","observed_orcids":["https://orcid.org/0000-0002-0937-6640"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Masahiro Hitomi","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5041530623","display_name":"Daniel J. Silver","orcid":"https://orcid.org/0000-0002-7085-2626","observed_orcids":["https://orcid.org/0000-0002-7085-2626"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Daniel J. Silver","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5110967891","display_name":"Qiulian Wu","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Qiulian Wu","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5058855845","display_name":"Poorva Sandlesh","orcid":"https://orcid.org/0000-0002-4775-7188","observed_orcids":["https://orcid.org/0000-0002-4775-7188"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Poorva Sandlesh","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5089511408","display_name":"Andrew Edward Sloan","orcid":"https://orcid.org/0000-0001-9607-5063","observed_orcids":["https://orcid.org/0000-0001-9607-5063"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Andrew E. Sloan","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5071922213","display_name":"Andrei A. Purmal","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Andrei A. Purmal","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5015550222","display_name":"Katerina V. Gurova","orcid":"https://orcid.org/0000-0001-9189-0712","observed_orcids":["https://orcid.org/0000-0001-9189-0712"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Katerina V. Gurova","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5021296578","display_name":"Jeremy N. Rich","orcid":"https://orcid.org/0000-0001-7845-5302","observed_orcids":["https://orcid.org/0000-0001-7845-5302"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Jeremy N. Rich","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5004589257","display_name":"Justin Durla Lathia","orcid":"https://orcid.org/0000-0003-3168-7290","observed_orcids":["https://orcid.org/0000-0003-3168-7290"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Justin D. Lathia","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5080998429","display_name":"George Robert Stark","orcid":"https://orcid.org/0000-0002-8776-9597","observed_orcids":["https://orcid.org/0000-0002-8776-9597"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"George R. Stark","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"last","author":{"id":"https://openalex.org/A5087254131","display_name":"Monica Venere","orcid":"https://orcid.org/0000-0001-6498-3390","observed_orcids":["https://orcid.org/0000-0001-6498-3390"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Monica Venere","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]}],"institutions":[],"countries_distinct_count":0,"institutions_distinct_count":0,"corresponding_author_ids":[],"corresponding_institution_ids":[],"apc_list":null,"apc_paid":null,"fwci":null,"has_fulltext":false,"cited_by_count":0,"citation_normalized_percentile":null,"cited_by_percentile_year":null,"biblio":{"volume":null,"issue":null,"first_page":null,"last_page":null},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10129","display_name":"Glioma Diagnosis and Treatment","score":0.9789999723434448,"subfield":{"id":"https://openalex.org/subfields/2716","display_name":"Genetics"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T10129","display_name":"Glioma Diagnosis and Treatment","score":0.9789999723434448,"subfield":{"id":"https://openalex.org/subfields/2716","display_name":"Genetics"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10336","display_name":"Cancer Cells and Metastasis","score":0.008999999612569809,"subfield":{"id":"https://openalex.org/subfields/2730","display_name":"Oncology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10631","display_name":"Cancer, Hypoxia, and Metabolism","score":0.000699999975040555,"subfield":{"id":"https://openalex.org/subfields/1306","display_name":"Cancer Research"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/glioblastoma-stem-cells","display_name":"glioblastoma stem cells","score":0.9919999837875366},{"id":"https://openalex.org/keywords/asymmetric-cell-division","display_name":"asymmetric cell division","score":0.9580000042915344},{"id":"https://openalex.org/keywords/mitosis","display_name":"mitosis","score":0.9670000076293945},{"id":"https://openalex.org/keywords/pharmacological-targeting","display_name":"pharmacological targeting","score":0.7739999890327454},{"id":"https://openalex.org/keywords/survival","display_name":"survival","score":0.4970000088214874}],"concepts":[{"id":"https://openalex.org/C2776194525","wikidata":"https://www.wikidata.org/wiki/Q282142","display_name":"Glioblastoma","level":2,"score":0.8404130339622498},{"id":"https://openalex.org/C502942594","wikidata":"https://www.wikidata.org/wiki/Q3421914","display_name":"Cancer research","level":1,"score":0.5847417712211609},{"id":"https://openalex.org/C64927066","wikidata":"https://www.wikidata.org/wiki/Q36293","display_name":"Histone","level":3,"score":0.5502776503562927},{"id":"https://openalex.org/C28328180","wikidata":"https://www.wikidata.org/wiki/Q48196","display_name":"Stem cell","level":2,"score":0.4963729977607727},{"id":"https://openalex.org/C2775962898","wikidata":"https://www.wikidata.org/wiki/Q5073152","display_name":"Chaperone (clinical)","level":2,"score":0.45091894268989563},{"id":"https://openalex.org/C95444343","wikidata":"https://www.wikidata.org/wiki/Q7141","display_name":"Cell biology","level":1,"score":0.38195502758026123},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.36646974086761475},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.2858777344226837},{"id":"https://openalex.org/C54355233","wikidata":"https://www.wikidata.org/wiki/Q7162","display_name":"Genetics","level":1,"score":0.13322123885154724},{"id":"https://openalex.org/C104317684","wikidata":"https://www.wikidata.org/wiki/Q7187","display_name":"Gene","level":2,"score":0.09500417113304138},{"id":"https://openalex.org/C142724271","wikidata":"https://www.wikidata.org/wiki/Q7208","display_name":"Pathology","level":1,"score":0.08099493384361267}],"mesh":[],"locations_count":1,"locations":[{"id":"doi:10.1158/0008-5472.22410549","doi":"https://doi.org/10.1158/0008-5472.22410549","is_oa":true,"landing_page_url":"http://dx.doi.org/10.1158/0008-5472.22410549","pdf_url":null,"source":null,"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"acceptedVersion","is_accepted":true,"is_published":false,"raw_source_name":"American Association for Cancer Research","raw_type":"posted-content"}],"best_oa_location":{"id":"doi:10.1158/0008-5472.22410549","doi":"https://doi.org/10.1158/0008-5472.22410549","is_oa":true,"landing_page_url":"http://dx.doi.org/10.1158/0008-5472.22410549","pdf_url":null,"source":null,"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"acceptedVersion","is_accepted":true,"is_published":false,"raw_source_name":"American Association for Cancer Research","raw_type":"posted-content"},"sustainable_development_goals":[{"id":"https://metadata.un.org/sdg/3","display_name":"Good health and well-being","score":0.7246000170707703}],"sustainable_development_goals_aurora":[],"study_designs":[],"awards":[],"funders":[],"has_content":{"pdf":false,"grobid_xml":false},"content_urls":null,"referenced_works_count":0,"referenced_works":[],"related_works":["https://openalex.org/W3120507315","https://openalex.org/W3198590948","https://openalex.org/W4206027097","https://openalex.org/W2972289391","https://openalex.org/W2967664227","https://openalex.org/W4327681888","https://openalex.org/W2055755414","https://openalex.org/W2959210034","https://openalex.org/W1987822850","https://openalex.org/W2767513209"],"abstract_inverted_index":{"Serum":[0],"increased":[1],"asymmetric":[2],"cell":[3],"division":[4],"in":[5],"GSCs":[6],"during":[7],"mitosis.":[8]},"counts_by_year":[],"updated_date":"2026-09-22T06:50:58.402377","created_date":"2025-10-10T00:00:00"}