{"id":"https://openalex.org/W4361234941","doi":"https://doi.org/10.1158/0008-5472.22417407.v1","title":"Supplementary Figure S7 from Myeloid Cells That Impair Immunotherapy Are Restored in Melanomas with Acquired Resistance to BRAF Inhibitors","display_name":"Supplementary Figure S7 from Myeloid Cells That Impair Immunotherapy Are Restored in Melanomas with Acquired Resistance to BRAF Inhibitors","publication_year":2023,"publication_date":"2023-03-31","ids":{"openalex":"https://openalex.org/W4361234941","doi":"https://doi.org/10.1158/0008-5472.22417407.v1"},"language":"en","primary_location":{"id":"doi:10.1158/0008-5472.22417407.v1","doi":"https://doi.org/10.1158/0008-5472.22417407.v1","is_oa":true,"landing_page_url":"http://dx.doi.org/10.1158/0008-5472.22417407.v1","pdf_url":null,"source":null,"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"acceptedVersion","is_accepted":true,"is_published":false,"raw_source_name":"American Association for Cancer Research","raw_type":"posted-content"},"volume":null,"type":"supplementary-materials","indexed_in":["crossref"],"open_access":{"is_oa":true,"oa_status":"gold","oa_url":"http://dx.doi.org/10.1158/0008-5472.22417407.v1","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5010958654","display_name":"Shannon M. Steinberg","orcid":"https://orcid.org/0000-0003-1711-2423","observed_orcids":["https://orcid.org/0000-0003-1711-2423"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Shannon M. Steinberg","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5027158701","display_name":"Tamer Basel Shabaneh","orcid":"https://orcid.org/0000-0001-7895-7134","observed_orcids":["https://orcid.org/0000-0001-7895-7134"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Tamer B. Shabaneh","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5058797896","display_name":"Peisheng Zhang","orcid":"https://orcid.org/0000-0002-6146-412X","observed_orcids":["https://orcid.org/0000-0002-6146-412X"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Peisheng Zhang","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5003564969","display_name":"Viktor Martyanov","orcid":"https://orcid.org/0000-0002-7964-425X","observed_orcids":["https://orcid.org/0000-0002-7964-425X"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Viktor Martyanov","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5100696696","display_name":"Zheng-Hui Li","orcid":"https://orcid.org/0000-0003-1284-0288","observed_orcids":["https://orcid.org/0000-0003-1284-0288"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Zhenghui Li","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5059645525","display_name":"Brian T. Malik","orcid":"https://orcid.org/0000-0002-9022-0044","observed_orcids":["https://orcid.org/0000-0002-9022-0044"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Brian T. Malik","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5066996051","display_name":"Tamara A. Wood","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Tamara A. Wood","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":null,"display_name":"Andrea Boni","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Andrea Boni","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5034746510","display_name":"Aleksey K. Molodtsov","orcid":"https://orcid.org/0000-0002-4629-808X","observed_orcids":["https://orcid.org/0000-0002-4629-808X"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Aleksey Molodtsov","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5011685851","display_name":"Christina Vadala Angeles","orcid":"https://orcid.org/0000-0002-6500-9589","observed_orcids":["https://orcid.org/0000-0002-6500-9589"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Christina V. Angeles","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5074770263","display_name":"Tyler Jay Curiel","orcid":"https://orcid.org/0000-0001-6962-9411","observed_orcids":["https://orcid.org/0000-0001-6962-9411"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Tyler J. Curiel","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5090205401","display_name":"Michael L. Whitfield","orcid":"https://orcid.org/0000-0002-0862-6003","observed_orcids":["https://orcid.org/0000-0002-0862-6003"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Michael L. Whitfield","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"last","author":{"id":"https://openalex.org/A5089219799","display_name":"Mary Jo Turk","orcid":"https://orcid.org/0000-0002-9612-8329","observed_orcids":["https://orcid.org/0000-0002-9612-8329"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Mary Jo Turk","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]}],"institutions":[],"countries_distinct_count":0,"institutions_distinct_count":0,"corresponding_author_ids":[],"corresponding_institution_ids":[],"apc_list":null,"apc_paid":null,"fwci":null,"has_fulltext":false,"cited_by_count":0,"citation_normalized_percentile":null,"cited_by_percentile_year":null,"biblio":{"volume":null,"issue":null,"first_page":null,"last_page":null},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T11533","display_name":"Melanoma and MAPK Pathways","score":0.5615000128746033,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T11533","display_name":"Melanoma and MAPK Pathways","score":0.5615000128746033,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10158","display_name":"Cancer Immunotherapy and Biomarkers","score":0.41990000009536743,"subfield":{"id":"https://openalex.org/subfields/2730","display_name":"Oncology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10580","display_name":"Immunotherapy and Immune Responses","score":0.0035000001080334187,"subfield":{"id":"https://openalex.org/subfields/2403","display_name":"Immunology"},"field":{"id":"https://openalex.org/fields/24","display_name":"Immunology and Microbiology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/myeloid-cells","display_name":"myeloid cells","score":0.8629999756813049},{"id":"https://openalex.org/keywords/immunotherapy-resistance","display_name":"immunotherapy resistance","score":0.8840000033378601},{"id":"https://openalex.org/keywords/melanoma","display_name":"melanoma","score":0.9900000095367432},{"id":"https://openalex.org/keywords/braf-inhibitors","display_name":"BRAF inhibitors","score":0.9110000133514404},{"id":"https://openalex.org/keywords/acquired-drug-resistance","display_name":"acquired drug resistance","score":0.871999979019165},{"id":"https://openalex.org/keywords/rag-deficient-mice","display_name":"RAG-deficient mice","score":0.7670000195503235},{"id":"https://openalex.org/keywords/cd8-deficient-mice","display_name":"CD8-deficient mice","score":0.9330000281333923},{"id":"https://openalex.org/keywords/immune-checkpoint-blockade","display_name":"immune checkpoint blockade","score":0.35899999737739563}],"concepts":[{"id":"https://openalex.org/C502942594","wikidata":"https://www.wikidata.org/wiki/Q3421914","display_name":"Cancer research","level":1,"score":0.6739574074745178},{"id":"https://openalex.org/C2777701055","wikidata":"https://www.wikidata.org/wiki/Q1427096","display_name":"Immunotherapy","level":3,"score":0.6371496319770813},{"id":"https://openalex.org/C167672396","wikidata":"https://www.wikidata.org/wiki/Q417800","display_name":"CD8","level":3,"score":0.5450887084007263},{"id":"https://openalex.org/C2994294914","wikidata":"https://www.wikidata.org/wiki/Q1645075","display_name":"Acquired resistance","level":3,"score":0.48680922389030457},{"id":"https://openalex.org/C2779282312","wikidata":"https://www.wikidata.org/wiki/Q1956561","display_name":"Myeloid","level":2,"score":0.4700514078140259},{"id":"https://openalex.org/C2994430510","wikidata":"https://www.wikidata.org/wiki/Q3270846","display_name":"Myeloid cells","level":3,"score":0.4658682346343994},{"id":"https://openalex.org/C57473165","wikidata":"https://www.wikidata.org/wiki/Q7315604","display_name":"Resistance (ecology)","level":2,"score":0.4243434965610504},{"id":"https://openalex.org/C2777658100","wikidata":"https://www.wikidata.org/wiki/Q180614","display_name":"Melanoma","level":2,"score":0.42221659421920776},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.407325804233551},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.3341246247291565},{"id":"https://openalex.org/C203014093","wikidata":"https://www.wikidata.org/wiki/Q101929","display_name":"Immunology","level":1,"score":0.31204932928085327},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.29681307077407837},{"id":"https://openalex.org/C8891405","wikidata":"https://www.wikidata.org/wiki/Q1059","display_name":"Immune system","level":2,"score":0.1731925904750824},{"id":"https://openalex.org/C121608353","wikidata":"https://www.wikidata.org/wiki/Q12078","display_name":"Cancer","level":2,"score":0.11611995100975037},{"id":"https://openalex.org/C18903297","wikidata":"https://www.wikidata.org/wiki/Q7150","display_name":"Ecology","level":1,"score":0.0}],"mesh":[],"locations_count":2,"locations":[{"id":"doi:10.1158/0008-5472.22417407.v1","doi":"https://doi.org/10.1158/0008-5472.22417407.v1","is_oa":true,"landing_page_url":"http://dx.doi.org/10.1158/0008-5472.22417407.v1","pdf_url":null,"source":null,"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"acceptedVersion","is_accepted":true,"is_published":false,"raw_source_name":"American Association for Cancer Research","raw_type":"posted-content"},{"id":"pmh:oai:figshare.com:article/22417407","doi":null,"is_oa":true,"landing_page_url":"https://figshare.com/articles/journal_contribution/Supplementary_Figure_S7_from_Myeloid_Cells_That_Impair_Immunotherapy_Are_Restored_in_Melanomas_with_Acquired_Resistance_to_BRAF_Inhibitors/22417407","pdf_url":null,"source":{"id":"https://openalex.org/S4377196282","display_name":"Figshare","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I4210132348","host_organization_name":"Figshare (United Kingdom)","host_organization_lineage":["https://openalex.org/I4210132348"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"","raw_type":"Text"}],"best_oa_location":{"id":"doi:10.1158/0008-5472.22417407.v1","doi":"https://doi.org/10.1158/0008-5472.22417407.v1","is_oa":true,"landing_page_url":"http://dx.doi.org/10.1158/0008-5472.22417407.v1","pdf_url":null,"source":null,"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"acceptedVersion","is_accepted":true,"is_published":false,"raw_source_name":"American Association for Cancer Research","raw_type":"posted-content"},"sustainable_development_goals":[{"score":0.9763000011444092,"id":"https://metadata.un.org/sdg/3","display_name":"Good health and well-being"}],"sustainable_development_goals_aurora":[],"study_designs":[],"awards":[],"funders":[],"has_content":{"grobid_xml":false,"pdf":false},"content_urls":null,"referenced_works_count":0,"referenced_works":[],"related_works":["https://openalex.org/W4361235008","https://openalex.org/W2588812529","https://openalex.org/W7171534120","https://openalex.org/W4385515643","https://openalex.org/W4416446266","https://openalex.org/W4362432241","https://openalex.org/W2982888477","https://openalex.org/W4362411434","https://openalex.org/W4361937495","https://openalex.org/W7005621372"],"abstract_inverted_index":{"BRAFi":[0],"responsiveness":[1],"and":[2,8],"resistance":[3],"kinetics":[4],"in":[5],"RAG":[6],"-/-":[7,10],"CD8":[9],"versus":[11],"wild-type":[12],"mice.":[13]},"counts_by_year":[],"updated_date":"2026-09-29T14:09:16.559479","created_date":"2023-03-31T00:00:00"}