{"id":"https://openalex.org/W4361007337","doi":"https://doi.org/10.1002/ajh.26922","title":"A phase II study of sintilimab, anlotinib, and pegaspargase sandwiched with radiotherapy as first\u2010line therapy in patients with newly diagnosed, stage I\u2013II extranodal natural\u2010killer/T\u2010cell lymphoma","display_name":"A phase II study of sintilimab, anlotinib, and pegaspargase sandwiched with radiotherapy as first\u2010line therapy in patients with newly diagnosed, stage I\u2013II extranodal natural\u2010killer/T\u2010cell lymphoma","publication_year":2023,"publication_date":"2023-03-27","ids":{"openalex":"https://openalex.org/W4361007337","doi":"https://doi.org/10.1002/ajh.26922","pmid":"https://pubmed.ncbi.nlm.nih.gov/36970971"},"language":"en","primary_location":{"id":"doi:10.1002/ajh.26922","doi":"https://doi.org/10.1002/ajh.26922","is_oa":true,"landing_page_url":"https://doi.org/10.1002/ajh.26922","pdf_url":"https://onlinelibrary.wiley.com/doi/pdfdirect/10.1002/ajh.26922","source":{"id":"https://openalex.org/S199810014","display_name":"American Journal of Hematology","issn_l":"0361-8609","issn":["0361-8609","1096-8652"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-b","doyens","jufo-2","ki-jl-2","medline","norway-1","poland-140","russia-white-list-1"],"host_organization":"https://openalex.org/P4310320595","host_organization_name":"Wiley","host_organization_lineage":["https://openalex.org/P4310320595"],"host_organization_lineage_names":["Wiley"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"American Journal of Hematology","raw_type":"journal-article"},"volume":null,"type":"article","indexed_in":["crossref","pubmed"],"open_access":{"is_oa":true,"oa_status":"bronze","oa_url":"https://onlinelibrary.wiley.com/doi/pdfdirect/10.1002/ajh.26922","any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5015287299","display_name":"Peng Sun","orcid":"https://orcid.org/0000-0003-3811-0371","observed_orcids":["https://orcid.org/0000-0003-3811-0371"]},"institutions":[{"id":"https://openalex.org/I4210146711","display_name":"Sun Yat-sen University Cancer Center","ror":"https://ror.org/0400g8r85","country_code":"CN","type":"healthcare","lineage":["https://openalex.org/I4210146711"]},{"id":"https://openalex.org/I4391768007","display_name":"State Key Laboratory of Oncology in South China","ror":"https://ror.org/04dn2ax39","country_code":null,"type":"facility","lineage":["https://openalex.org/I157773358","https://openalex.org/I4391768007"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Peng Sun","raw_affiliation_strings":["Department of Medical Oncology Sun Yat\u2010Sen University Cancer Center  Guangzhou 510060 China","State Key Laboratory of Oncology in South China Collaborative Innovation Center for Cancer Medicine  Guangzhou 510060 China","Department of Medical Oncology, Sun Yat-Sen University Cancer Center, Guangzhou, 510060 China","State Key Laboratory of Oncology in South China, Collaborative Innovation Center for Cancer Medicine, Guangzhou, 510060 China"],"raw_orcid":"https://orcid.org/0000-0003-3811-0371","affiliations":[{"raw_affiliation_string":"Department of Medical Oncology Sun Yat\u2010Sen University Cancer Center  Guangzhou 510060 China","institution_ids":["https://openalex.org/I4210146711"]},{"raw_affiliation_string":"State Key Laboratory of Oncology in South China Collaborative Innovation Center for Cancer Medicine  Guangzhou 510060 China","institution_ids":["https://openalex.org/I4391768007"]},{"raw_affiliation_string":"Department of Medical Oncology, Sun Yat-Sen University Cancer Center, Guangzhou, 510060 China","institution_ids":["https://openalex.org/I4210146711"]},{"raw_affiliation_string":"State Key Laboratory of Oncology in South China, Collaborative Innovation Center for Cancer Medicine, Guangzhou, 510060 China","institution_ids":["https://openalex.org/I4391768007"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5101870342","display_name":"Yajun Li","orcid":"https://orcid.org/0000-0002-2728-3237","observed_orcids":["https://orcid.org/0000-0002-2728-3237"]},"institutions":[{"id":"https://openalex.org/I139660479","display_name":"Central South University","ror":"https://ror.org/00f1zfq44","country_code":"CN","type":"education","lineage":["https://openalex.org/I139660479"]},{"id":"https://openalex.org/I4210115624","display_name":"Hunan Cancer Hospital","ror":"https://ror.org/025020z88","country_code":"CN","type":"healthcare","lineage":["https://openalex.org/I4210115624"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Yajun Li","raw_affiliation_strings":["Department of Lymphoma and Hematology Hunan Cancer Hospital  Changsha 410013 China","The Affiliated Cancer Hospital of Xiangya School of Medicine Central South University  Changsha 410000 China","Department of Lymphoma and Hematology, Hunan Cancer Hospital, Changsha, 410013 China","The Affiliated Cancer Hospital of Xiangya School of Medicine, Central South University, Changsha, 410000 China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Lymphoma and Hematology Hunan Cancer Hospital  Changsha 410013 China","institution_ids":["https://openalex.org/I4210115624"]},{"raw_affiliation_string":"The Affiliated Cancer Hospital of Xiangya School of Medicine Central South University  Changsha 410000 China","institution_ids":["https://openalex.org/I139660479"]},{"raw_affiliation_string":"Department of Lymphoma and Hematology, Hunan Cancer Hospital, Changsha, 410013 China","institution_ids":["https://openalex.org/I4210115624"]},{"raw_affiliation_string":"The Affiliated Cancer Hospital of Xiangya School of Medicine, Central South University, Changsha, 410000 China","institution_ids":["https://openalex.org/I139660479"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5100331581","display_name":"Cong Li","orcid":"https://orcid.org/0000-0002-2617-2455","observed_orcids":["https://orcid.org/0000-0002-2617-2455","https://orcid.org/0009-0009-2867-2419","https://orcid.org/0000-0001-5319-680X"]},"institutions":[{"id":"https://openalex.org/I4210098734","display_name":"Zhejiang Cancer Hospital","ror":"https://ror.org/0144s0951","country_code":"CN","type":"healthcare","lineage":["https://openalex.org/I4210098734"]},{"id":"https://openalex.org/I4210165038","display_name":"University of Chinese Academy of Sciences","ror":"https://ror.org/05qbk4x57","country_code":"CN","type":"education","lineage":["https://openalex.org/I19820366","https://openalex.org/I4210165038"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Cong Li","raw_affiliation_strings":["Department of Lymphoma The Cancer Hospital of the University of Chinese Academy of Sciences (Zhejiang Cancer Hospital), Institute of Basic Medicine and Cancer, Chinese Academy of Sciences  Hangzhou 310012 China","Department of Lymphoma, The Cancer Hospital of the University of Chinese Academy of Sciences (Zhejiang Cancer Hospital), Institute of Basic Medicine and Cancer, Chinese Academy of Sciences, Hangzhou, 310012 China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Lymphoma The Cancer Hospital of the University of Chinese Academy of Sciences (Zhejiang Cancer Hospital), Institute of Basic Medicine and Cancer, Chinese Academy of Sciences  Hangzhou 310012 China","institution_ids":["https://openalex.org/I4210098734","https://openalex.org/I4210165038"]},{"raw_affiliation_string":"Department of Lymphoma, The Cancer Hospital of the University of Chinese Academy of Sciences (Zhejiang Cancer Hospital), Institute of Basic Medicine and Cancer, Chinese Academy of Sciences, Hangzhou, 310012 China","institution_ids":["https://openalex.org/I4210098734","https://openalex.org/I4210165038"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5054632006","display_name":"Kexing Ren","orcid":"https://orcid.org/0009-0007-0445-4586","observed_orcids":["https://orcid.org/0009-0007-0445-4586"]},"institutions":[{"id":"https://openalex.org/I24185976","display_name":"Sichuan University","ror":"https://ror.org/011ashp19","country_code":"CN","type":"education","lineage":["https://openalex.org/I24185976"]},{"id":"https://openalex.org/I2800091995","display_name":"West China Medical Center of Sichuan University","ror":"https://ror.org/040nggs60","country_code":"CN","type":"healthcare","lineage":["https://openalex.org/I24185976","https://openalex.org/I2800091995"]},{"id":"https://openalex.org/I4210089761","display_name":"West China Hospital of Sichuan University","ror":"https://ror.org/007mrxy13","country_code":"CN","type":"healthcare","lineage":["https://openalex.org/I4210089761"]},{"id":"https://openalex.org/I4391768003","display_name":"State Key Laboratory of Biotherapy","ror":"https://ror.org/00x43yy22","country_code":null,"type":"facility","lineage":["https://openalex.org/I24185976","https://openalex.org/I4391768003"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Kexing Ren","raw_affiliation_strings":["Division of Medical Oncology, Cancer Center and State Key Laboratory of Biotherapy Sichuan University West China Hospital  Chengdu China","Division of Medical Oncology, Cancer Center and State Key Laboratory of Biotherapy, Sichuan University West China Hospital, Chengdu, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Division of Medical Oncology, Cancer Center and State Key Laboratory of Biotherapy Sichuan University West China Hospital  Chengdu China","institution_ids":["https://openalex.org/I24185976","https://openalex.org/I2800091995","https://openalex.org/I4210089761","https://openalex.org/I4391768003"]},{"raw_affiliation_string":"Division of Medical Oncology, Cancer Center and State Key Laboratory of Biotherapy, Sichuan University West China Hospital, Chengdu, China","institution_ids":["https://openalex.org/I24185976","https://openalex.org/I4210089761","https://openalex.org/I4391768003"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5100445230","display_name":"Yu Wang","orcid":"https://orcid.org/0000-0002-5394-0050","observed_orcids":["https://orcid.org/0000-0002-5394-0050"]},"institutions":[{"id":"https://openalex.org/I4210146711","display_name":"Sun Yat-sen University Cancer Center","ror":"https://ror.org/0400g8r85","country_code":"CN","type":"healthcare","lineage":["https://openalex.org/I4210146711"]},{"id":"https://openalex.org/I4391768007","display_name":"State Key Laboratory of Oncology in South China","ror":"https://ror.org/04dn2ax39","country_code":null,"type":"facility","lineage":["https://openalex.org/I157773358","https://openalex.org/I4391768007"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Yu Wang","raw_affiliation_strings":["Department of Medical Oncology Sun Yat\u2010Sen University Cancer Center  Guangzhou 510060 China","State Key Laboratory of Oncology in South China Collaborative Innovation Center for Cancer Medicine  Guangzhou 510060 China","Department of Medical Oncology, Sun Yat-Sen University Cancer Center, Guangzhou, 510060 China","State Key Laboratory of Oncology in South China, Collaborative Innovation Center for Cancer Medicine, Guangzhou, 510060 China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Medical Oncology Sun Yat\u2010Sen University Cancer Center  Guangzhou 510060 China","institution_ids":["https://openalex.org/I4210146711"]},{"raw_affiliation_string":"State Key Laboratory of Oncology in South China Collaborative Innovation Center for Cancer Medicine  Guangzhou 510060 China","institution_ids":["https://openalex.org/I4391768007"]},{"raw_affiliation_string":"Department of Medical Oncology, Sun Yat-Sen University Cancer Center, Guangzhou, 510060 China","institution_ids":["https://openalex.org/I4210146711"]},{"raw_affiliation_string":"State Key Laboratory of Oncology in South China, Collaborative Innovation Center for Cancer Medicine, Guangzhou, 510060 China","institution_ids":["https://openalex.org/I4391768007"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5101775498","display_name":"Hang Yang","orcid":"https://orcid.org/0000-0002-5777-3800","observed_orcids":["https://orcid.org/0000-0002-5777-3800"]},"institutions":[{"id":"https://openalex.org/I4210098734","display_name":"Zhejiang Cancer Hospital","ror":"https://ror.org/0144s0951","country_code":"CN","type":"healthcare","lineage":["https://openalex.org/I4210098734"]},{"id":"https://openalex.org/I4210146711","display_name":"Sun Yat-sen University Cancer Center","ror":"https://ror.org/0400g8r85","country_code":"CN","type":"healthcare","lineage":["https://openalex.org/I4210146711"]},{"id":"https://openalex.org/I4210165038","display_name":"University of Chinese Academy of Sciences","ror":"https://ror.org/05qbk4x57","country_code":"CN","type":"education","lineage":["https://openalex.org/I19820366","https://openalex.org/I4210165038"]},{"id":"https://openalex.org/I4391768007","display_name":"State Key Laboratory of Oncology in South China","ror":"https://ror.org/04dn2ax39","country_code":null,"type":"facility","lineage":["https://openalex.org/I157773358","https://openalex.org/I4391768007"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Hang Yang","raw_affiliation_strings":["Department of Lymphoma The Cancer Hospital of the University of Chinese Academy of Sciences (Zhejiang Cancer Hospital), Institute of Basic Medicine and Cancer, Chinese Academy of Sciences  Hangzhou 310012 China","Department of Medical Oncology Sun Yat\u2010Sen University Cancer Center  Guangzhou 510060 China","State Key Laboratory of Oncology in South China Collaborative Innovation Center for Cancer Medicine  Guangzhou 510060 China","Department of Medical Oncology, Sun Yat-Sen University Cancer Center, Guangzhou, 510060 China","State Key Laboratory of Oncology in South China, Collaborative Innovation Center for Cancer Medicine, Guangzhou, 510060 China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Lymphoma The Cancer Hospital of the University of Chinese Academy of Sciences (Zhejiang Cancer Hospital), Institute of Basic Medicine and Cancer, Chinese Academy of Sciences  Hangzhou 310012 China","institution_ids":["https://openalex.org/I4210098734","https://openalex.org/I4210165038"]},{"raw_affiliation_string":"Department of Medical Oncology Sun Yat\u2010Sen University Cancer Center  Guangzhou 510060 China","institution_ids":["https://openalex.org/I4210146711"]},{"raw_affiliation_string":"State Key Laboratory of Oncology in South China Collaborative Innovation Center for Cancer Medicine  Guangzhou 510060 China","institution_ids":["https://openalex.org/I4391768007"]},{"raw_affiliation_string":"Department of Medical Oncology, Sun Yat-Sen University Cancer Center, Guangzhou, 510060 China","institution_ids":["https://openalex.org/I4210146711"]},{"raw_affiliation_string":"State Key Laboratory of Oncology in South China, Collaborative Innovation Center for Cancer Medicine, Guangzhou, 510060 China","institution_ids":["https://openalex.org/I4391768007"]}]},{"author_position":"middle","author":{"id":null,"display_name":"Hang Yang","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I4210098734","display_name":"Zhejiang Cancer Hospital","ror":"https://ror.org/0144s0951","country_code":"CN","type":"healthcare","lineage":["https://openalex.org/I4210098734"]},{"id":"https://openalex.org/I4210146711","display_name":"Sun Yat-sen University Cancer Center","ror":"https://ror.org/0400g8r85","country_code":"CN","type":"healthcare","lineage":["https://openalex.org/I4210146711"]},{"id":"https://openalex.org/I4210165038","display_name":"University of Chinese Academy of Sciences","ror":"https://ror.org/05qbk4x57","country_code":"CN","type":"education","lineage":["https://openalex.org/I19820366","https://openalex.org/I4210165038"]},{"id":"https://openalex.org/I4391768007","display_name":"State Key Laboratory of Oncology in South China","ror":"https://ror.org/04dn2ax39","country_code":null,"type":"facility","lineage":["https://openalex.org/I157773358","https://openalex.org/I4391768007"]}],"countries":["CN"],"is_corresponding":true,"raw_author_name":"Hang Yang","raw_affiliation_strings":["Department of Lymphoma The Cancer Hospital of the University of Chinese Academy of Sciences (Zhejiang Cancer Hospital), Institute of Basic Medicine and Cancer, Chinese Academy of Sciences  Hangzhou 310012 China","Department of Medical Oncology Sun Yat\u2010Sen University Cancer Center  Guangzhou 510060 China","State Key Laboratory of Oncology in South China Collaborative Innovation Center for Cancer Medicine  Guangzhou 510060 China","Department of Medical Oncology, Sun Yat-Sen University Cancer Center, Guangzhou, 510060 China","State Key Laboratory of Oncology in South China, Collaborative Innovation Center for Cancer Medicine, Guangzhou, 510060 China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Lymphoma The Cancer Hospital of the University of Chinese Academy of Sciences (Zhejiang Cancer Hospital), Institute of Basic Medicine and Cancer, Chinese Academy of Sciences  Hangzhou 310012 China","institution_ids":["https://openalex.org/I4210098734","https://openalex.org/I4210165038"]},{"raw_affiliation_string":"Department of Medical Oncology Sun Yat\u2010Sen University Cancer Center  Guangzhou 510060 China","institution_ids":["https://openalex.org/I4210146711"]},{"raw_affiliation_string":"State Key Laboratory of Oncology in South China Collaborative Innovation Center for Cancer Medicine  Guangzhou 510060 China","institution_ids":["https://openalex.org/I4391768007"]},{"raw_affiliation_string":"Department of Medical Oncology, Sun Yat-Sen University Cancer Center, Guangzhou, 510060 China","institution_ids":["https://openalex.org/I4210146711"]},{"raw_affiliation_string":"State Key Laboratory of Oncology in South China, Collaborative Innovation Center for Cancer Medicine, Guangzhou, 510060 China","institution_ids":["https://openalex.org/I4391768007"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5101611813","display_name":"Wenqi Jiang","orcid":"https://orcid.org/0000-0002-4302-9861","observed_orcids":["https://orcid.org/0000-0002-4302-9861"]},"institutions":[{"id":"https://openalex.org/I24185976","display_name":"Sichuan University","ror":"https://ror.org/011ashp19","country_code":"CN","type":"education","lineage":["https://openalex.org/I24185976"]},{"id":"https://openalex.org/I4210089761","display_name":"West China Hospital of Sichuan University","ror":"https://ror.org/007mrxy13","country_code":"CN","type":"healthcare","lineage":["https://openalex.org/I4210089761"]},{"id":"https://openalex.org/I4210146711","display_name":"Sun Yat-sen University Cancer Center","ror":"https://ror.org/0400g8r85","country_code":"CN","type":"healthcare","lineage":["https://openalex.org/I4210146711"]},{"id":"https://openalex.org/I4391768003","display_name":"State Key Laboratory of Biotherapy","ror":"https://ror.org/00x43yy22","country_code":null,"type":"facility","lineage":["https://openalex.org/I24185976","https://openalex.org/I4391768003"]},{"id":"https://openalex.org/I4391768007","display_name":"State Key Laboratory of Oncology in South China","ror":"https://ror.org/04dn2ax39","country_code":null,"type":"facility","lineage":["https://openalex.org/I157773358","https://openalex.org/I4391768007"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Wenqi Jiang","raw_affiliation_strings":["Department of Medical Oncology Sun Yat\u2010Sen University Cancer Center  Guangzhou 510060 China","State Key Laboratory of Oncology in South China Collaborative Innovation Center for Cancer Medicine  Guangzhou 510060 China","Division of Medical Oncology, Cancer Center and State Key Laboratory of Biotherapy, Sichuan University West China Hospital, Chengdu, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Medical Oncology Sun Yat\u2010Sen University Cancer Center  Guangzhou 510060 China","institution_ids":["https://openalex.org/I4210146711"]},{"raw_affiliation_string":"State Key Laboratory of Oncology in South China Collaborative Innovation Center for Cancer Medicine  Guangzhou 510060 China","institution_ids":["https://openalex.org/I4391768007"]},{"raw_affiliation_string":"Division of Medical Oncology, Cancer Center and State Key Laboratory of Biotherapy, Sichuan University West China Hospital, Chengdu, China","institution_ids":["https://openalex.org/I24185976","https://openalex.org/I4210089761","https://openalex.org/I4391768003"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5026127833","display_name":"Liqun Zou","orcid":"https://orcid.org/0000-0003-4090-7793","observed_orcids":["https://orcid.org/0000-0003-4090-7793","https://orcid.org/0000-0002-7074-2574","https://orcid.org/0009-0003-1349-920X","https://orcid.org/0009-0005-8061-4014"]},"institutions":[{"id":"https://openalex.org/I24185976","display_name":"Sichuan University","ror":"https://ror.org/011ashp19","country_code":"CN","type":"education","lineage":["https://openalex.org/I24185976"]},{"id":"https://openalex.org/I2800091995","display_name":"West China Medical Center of Sichuan University","ror":"https://ror.org/040nggs60","country_code":"CN","type":"healthcare","lineage":["https://openalex.org/I24185976","https://openalex.org/I2800091995"]},{"id":"https://openalex.org/I4210089761","display_name":"West China Hospital of Sichuan University","ror":"https://ror.org/007mrxy13","country_code":"CN","type":"healthcare","lineage":["https://openalex.org/I4210089761"]},{"id":"https://openalex.org/I4210098734","display_name":"Zhejiang Cancer Hospital","ror":"https://ror.org/0144s0951","country_code":"CN","type":"healthcare","lineage":["https://openalex.org/I4210098734"]},{"id":"https://openalex.org/I4210165038","display_name":"University of Chinese Academy of Sciences","ror":"https://ror.org/05qbk4x57","country_code":"CN","type":"education","lineage":["https://openalex.org/I19820366","https://openalex.org/I4210165038"]},{"id":"https://openalex.org/I4391768003","display_name":"State Key Laboratory of Biotherapy","ror":"https://ror.org/00x43yy22","country_code":null,"type":"facility","lineage":["https://openalex.org/I24185976","https://openalex.org/I4391768003"]}],"countries":["CN"],"is_corresponding":true,"raw_author_name":"Liqun Zou","raw_affiliation_strings":["Division of Medical Oncology, Cancer Center and State Key Laboratory of Biotherapy Sichuan University West China Hospital  Chengdu China","Department of Lymphoma, The Cancer Hospital of the University of Chinese Academy of Sciences (Zhejiang Cancer Hospital), Institute of Basic Medicine and Cancer, Chinese Academy of Sciences, Hangzhou, 310012 China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Division of Medical Oncology, Cancer Center and State Key Laboratory of Biotherapy Sichuan University West China Hospital  Chengdu China","institution_ids":["https://openalex.org/I24185976","https://openalex.org/I2800091995","https://openalex.org/I4210089761","https://openalex.org/I4391768003"]},{"raw_affiliation_string":"Department of Lymphoma, The Cancer Hospital of the University of Chinese Academy of Sciences (Zhejiang Cancer Hospital), Institute of Basic Medicine and Cancer, Chinese Academy of Sciences, Hangzhou, 310012 China","institution_ids":["https://openalex.org/I4210098734","https://openalex.org/I4210165038"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5046279416","display_name":"Haiyan Yang","orcid":"https://orcid.org/0000-0001-5185-4696","observed_orcids":["https://orcid.org/0000-0001-5185-4696","https://orcid.org/0000-0002-1371-3734"]},"institutions":[{"id":"https://openalex.org/I139660479","display_name":"Central South University","ror":"https://ror.org/00f1zfq44","country_code":"CN","type":"education","lineage":["https://openalex.org/I139660479"]},{"id":"https://openalex.org/I4210098734","display_name":"Zhejiang Cancer Hospital","ror":"https://ror.org/0144s0951","country_code":"CN","type":"healthcare","lineage":["https://openalex.org/I4210098734"]},{"id":"https://openalex.org/I4210115624","display_name":"Hunan Cancer Hospital","ror":"https://ror.org/025020z88","country_code":"CN","type":"healthcare","lineage":["https://openalex.org/I4210115624"]},{"id":"https://openalex.org/I4210146711","display_name":"Sun Yat-sen University Cancer Center","ror":"https://ror.org/0400g8r85","country_code":"CN","type":"healthcare","lineage":["https://openalex.org/I4210146711"]},{"id":"https://openalex.org/I4210165038","display_name":"University of Chinese Academy of Sciences","ror":"https://ror.org/05qbk4x57","country_code":"CN","type":"education","lineage":["https://openalex.org/I19820366","https://openalex.org/I4210165038"]},{"id":"https://openalex.org/I4391768007","display_name":"State Key Laboratory of Oncology in South China","ror":"https://ror.org/04dn2ax39","country_code":null,"type":"facility","lineage":["https://openalex.org/I157773358","https://openalex.org/I4391768007"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Haiyan Yang","raw_affiliation_strings":["Department of Lymphoma The Cancer Hospital of the University of Chinese Academy of Sciences (Zhejiang Cancer Hospital), Institute of Basic Medicine and Cancer, Chinese Academy of Sciences  Hangzhou 310012 China","Department of Medical Oncology Sun Yat\u2010Sen University Cancer Center  Guangzhou 510060 China","State Key Laboratory of Oncology in South China Collaborative Innovation Center for Cancer Medicine  Guangzhou 510060 China","Department of Lymphoma and Hematology, Hunan Cancer Hospital, Changsha, 410013 China","The Affiliated Cancer Hospital of Xiangya School of Medicine, Central South University, Changsha, 410000 China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Lymphoma The Cancer Hospital of the University of Chinese Academy of Sciences (Zhejiang Cancer Hospital), Institute of Basic Medicine and Cancer, Chinese Academy of Sciences  Hangzhou 310012 China","institution_ids":["https://openalex.org/I4210098734","https://openalex.org/I4210165038"]},{"raw_affiliation_string":"Department of Medical Oncology Sun Yat\u2010Sen University Cancer Center  Guangzhou 510060 China","institution_ids":["https://openalex.org/I4210146711"]},{"raw_affiliation_string":"State Key Laboratory of Oncology in South China Collaborative Innovation Center for Cancer Medicine  Guangzhou 510060 China","institution_ids":["https://openalex.org/I4391768007"]},{"raw_affiliation_string":"Department of Lymphoma and Hematology, Hunan Cancer Hospital, Changsha, 410013 China","institution_ids":["https://openalex.org/I4210115624"]},{"raw_affiliation_string":"The Affiliated Cancer Hospital of Xiangya School of Medicine, Central South University, Changsha, 410000 China","institution_ids":["https://openalex.org/I139660479"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5046279416","display_name":"Haiyan Yang","orcid":"https://orcid.org/0000-0001-5185-4696","observed_orcids":["https://orcid.org/0000-0001-5185-4696","https://orcid.org/0000-0002-1371-3734"]},"institutions":[{"id":"https://openalex.org/I4210098734","display_name":"Zhejiang Cancer Hospital","ror":"https://ror.org/0144s0951","country_code":"CN","type":"healthcare","lineage":["https://openalex.org/I4210098734"]},{"id":"https://openalex.org/I4210146711","display_name":"Sun Yat-sen University Cancer Center","ror":"https://ror.org/0400g8r85","country_code":"CN","type":"healthcare","lineage":["https://openalex.org/I4210146711"]},{"id":"https://openalex.org/I4210165038","display_name":"University of Chinese Academy of Sciences","ror":"https://ror.org/05qbk4x57","country_code":"CN","type":"education","lineage":["https://openalex.org/I19820366","https://openalex.org/I4210165038"]},{"id":"https://openalex.org/I4391768007","display_name":"State Key Laboratory of Oncology in South China","ror":"https://ror.org/04dn2ax39","country_code":null,"type":"facility","lineage":["https://openalex.org/I157773358","https://openalex.org/I4391768007"]}],"countries":["CN"],"is_corresponding":true,"raw_author_name":"Haiyan Yang","raw_affiliation_strings":["Department of Lymphoma The Cancer Hospital of the University of Chinese Academy of Sciences (Zhejiang Cancer Hospital), Institute of Basic Medicine and Cancer, Chinese Academy of Sciences  Hangzhou 310012 China","Department of Medical Oncology Sun Yat\u2010Sen University Cancer Center  Guangzhou 510060 China","State Key Laboratory of Oncology in South China Collaborative Innovation Center for Cancer Medicine  Guangzhou 510060 China","Department of Medical Oncology, Sun Yat-Sen University Cancer Center, Guangzhou, 510060 China","State Key Laboratory of Oncology in South China, Collaborative Innovation Center for Cancer Medicine, Guangzhou, 510060 China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Lymphoma The Cancer Hospital of the University of Chinese Academy of Sciences (Zhejiang Cancer Hospital), Institute of Basic Medicine and Cancer, Chinese Academy of Sciences  Hangzhou 310012 China","institution_ids":["https://openalex.org/I4210098734","https://openalex.org/I4210165038"]},{"raw_affiliation_string":"Department of Medical Oncology Sun Yat\u2010Sen University Cancer Center  Guangzhou 510060 China","institution_ids":["https://openalex.org/I4210146711"]},{"raw_affiliation_string":"State Key Laboratory of Oncology in South China Collaborative Innovation Center for Cancer Medicine  Guangzhou 510060 China","institution_ids":["https://openalex.org/I4391768007"]},{"raw_affiliation_string":"Department of Medical Oncology, Sun Yat-Sen University Cancer Center, Guangzhou, 510060 China","institution_ids":["https://openalex.org/I4210146711"]},{"raw_affiliation_string":"State Key Laboratory of Oncology in South China, Collaborative Innovation Center for Cancer Medicine, Guangzhou, 510060 China","institution_ids":["https://openalex.org/I4391768007"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5062072304","display_name":"Hui Zhou","orcid":"https://orcid.org/0000-0001-9909-5051","observed_orcids":["https://orcid.org/0000-0001-9909-5051"]},"institutions":[{"id":"https://openalex.org/I139660479","display_name":"Central South University","ror":"https://ror.org/00f1zfq44","country_code":"CN","type":"education","lineage":["https://openalex.org/I139660479"]},{"id":"https://openalex.org/I4210115624","display_name":"Hunan Cancer Hospital","ror":"https://ror.org/025020z88","country_code":"CN","type":"healthcare","lineage":["https://openalex.org/I4210115624"]}],"countries":["CN"],"is_corresponding":true,"raw_author_name":"Hui Zhou","raw_affiliation_strings":["Department of Lymphoma and Hematology Hunan Cancer Hospital  Changsha 410013 China","The Affiliated Cancer Hospital of Xiangya School of Medicine Central South University  Changsha 410000 China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Lymphoma and Hematology Hunan Cancer Hospital  Changsha 410013 China","institution_ids":["https://openalex.org/I4210115624"]},{"raw_affiliation_string":"The Affiliated Cancer Hospital of Xiangya School of Medicine Central South University  Changsha 410000 China","institution_ids":["https://openalex.org/I139660479"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5011502144","display_name":"Zhiming Li","orcid":"https://orcid.org/0000-0001-9730-9917","observed_orcids":["https://orcid.org/0000-0001-9730-9917"]},"institutions":[{"id":"https://openalex.org/I4210146711","display_name":"Sun Yat-sen University Cancer Center","ror":"https://ror.org/0400g8r85","country_code":"CN","type":"healthcare","lineage":["https://openalex.org/I4210146711"]},{"id":"https://openalex.org/I4391768007","display_name":"State Key Laboratory of Oncology in South China","ror":"https://ror.org/04dn2ax39","country_code":null,"type":"facility","lineage":["https://openalex.org/I157773358","https://openalex.org/I4391768007"]}],"countries":["CN"],"is_corresponding":true,"raw_author_name":"Zhi\u2010Ming Li","raw_affiliation_strings":["Department of Medical Oncology Sun Yat\u2010Sen University Cancer Center  Guangzhou 510060 China","State Key Laboratory of Oncology in South China Collaborative Innovation Center for Cancer Medicine  Guangzhou 510060 China"],"raw_orcid":"https://orcid.org/0000-0001-9730-9917","affiliations":[{"raw_affiliation_string":"Department of Medical Oncology Sun Yat\u2010Sen University Cancer Center  Guangzhou 510060 China","institution_ids":["https://openalex.org/I4210146711"]},{"raw_affiliation_string":"State Key Laboratory of Oncology in South China Collaborative Innovation Center for Cancer Medicine  Guangzhou 510060 China","institution_ids":["https://openalex.org/I4391768007"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":10,"corresponding_author_ids":["https://openalex.org/A5011502144","https://openalex.org/A5026127833","https://openalex.org/A5046279416","https://openalex.org/A5062072304"],"corresponding_institution_ids":["https://openalex.org/I139660479","https://openalex.org/I24185976","https://openalex.org/I2800091995","https://openalex.org/I4210089761","https://openalex.org/I4210098734","https://openalex.org/I4210115624","https://openalex.org/I4210146711","https://openalex.org/I4210165038","https://openalex.org/I4391768003","https://openalex.org/I4391768007"],"apc_list":{"value":4940,"currency":"USD","value_usd":4940},"apc_paid":null,"fwci":4.0819,"has_fulltext":true,"cited_by_count":25,"citation_normalized_percentile":{"value":0.94713682,"is_in_top_1_percent":false,"is_in_top_10_percent":true},"cited_by_percentile_year":{"min":93,"max":99},"biblio":{"volume":"98","issue":"7","first_page":"1043","last_page":"1051"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10185","display_name":"Lymphoma Diagnosis and Treatment","score":0.9926999807357788,"subfield":{"id":"https://openalex.org/subfields/2734","display_name":"Pathology and Forensic Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T10185","display_name":"Lymphoma Diagnosis and Treatment","score":0.9926999807357788,"subfield":{"id":"https://openalex.org/subfields/2734","display_name":"Pathology and Forensic Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10685","display_name":"Viral-associated cancers and disorders","score":0.004399999976158142,"subfield":{"id":"https://openalex.org/subfields/2730","display_name":"Oncology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T11811","display_name":"Cutaneous lymphoproliferative disorders research","score":0.0005000000237487257,"subfield":{"id":"https://openalex.org/subfields/2708","display_name":"Dermatology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/extranodal-nk-t-cell-lymphoma-nasal-type","display_name":"extranodal NK/T-cell lymphoma, nasal type","score":0.9210000038146973},{"id":"https://openalex.org/keywords/sintilimab","display_name":"sintilimab","score":0.9890000224113464},{"id":"https://openalex.org/keywords/anlotinib","display_name":"anlotinib","score":0.9950000047683716},{"id":"https://openalex.org/keywords/pegaspargase","display_name":"pegaspargase","score":0.9980000257492065},{"id":"https://openalex.org/keywords/intensity-modulated-radiotherapy","display_name":"intensity-modulated radiotherapy","score":0.8610000014305115},{"id":"https://openalex.org/keywords/first-line-treatment","display_name":"first-line therapy","score":0.8420000076293945},{"id":"https://openalex.org/keywords/complete-response-rate","display_name":"complete response rate","score":0.6240000128746033},{"id":"https://openalex.org/keywords/progression-free-survival","display_name":"progression-free survival","score":0.781000018119812},{"id":"https://openalex.org/keywords/overall-survival","display_name":"overall survival","score":0.8080000281333923},{"id":"https://openalex.org/keywords/treatment-related-adverse-events","display_name":"treatment-related adverse events","score":0.75},{"id":"https://openalex.org/keywords/pd-1-inhibitors","display_name":"PD-1 inhibitors","score":0.6209999918937683},{"id":"https://openalex.org/keywords/tyrosine-kinase-inhibitors","display_name":"tyrosine kinase inhibitors","score":0.9049999713897705},{"id":"https://openalex.org/keywords/immunotherapy","display_name":"immunotherapy","score":0.3610000014305115},{"id":"https://openalex.org/keywords/localized-lymphoma","display_name":"localized lymphoma","score":0.8159999847412109},{"id":"https://openalex.org/keywords/combination-therapy","display_name":"combination therapy","score":0.33000001311302185}],"concepts":[{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.8249465227127075},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.6539306640625},{"id":"https://openalex.org/C197934379","wikidata":"https://www.wikidata.org/wiki/Q2047938","display_name":"Adverse effect","level":2,"score":0.6170158386230469},{"id":"https://openalex.org/C509974204","wikidata":"https://www.wikidata.org/wiki/Q180507","display_name":"Radiation therapy","level":2,"score":0.5867938995361328},{"id":"https://openalex.org/C90924648","wikidata":"https://www.wikidata.org/wiki/Q120569","display_name":"Gastroenterology","level":1,"score":0.5831718444824219},{"id":"https://openalex.org/C203092338","wikidata":"https://www.wikidata.org/wiki/Q1340863","display_name":"Clinical endpoint","level":3,"score":0.5755926966667175},{"id":"https://openalex.org/C31760486","wikidata":"https://www.wikidata.org/wiki/Q7180990","display_name":"Phases of clinical research","level":3,"score":0.5157237648963928},{"id":"https://openalex.org/C29730261","wikidata":"https://www.wikidata.org/wiki/Q274160","display_name":"Toxicity","level":2,"score":0.3664761781692505},{"id":"https://openalex.org/C141071460","wikidata":"https://www.wikidata.org/wiki/Q40821","display_name":"Surgery","level":1,"score":0.355258584022522},{"id":"https://openalex.org/C535046627","wikidata":"https://www.wikidata.org/wiki/Q30612","display_name":"Clinical trial","level":2,"score":0.30412402749061584}],"mesh":[{"descriptor_ui":"D000971","descriptor_name":"Antineoplastic Combined Chemotherapy Protocols","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000971","descriptor_name":"Antineoplastic Combined Chemotherapy Protocols","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000971","descriptor_name":"Antineoplastic Combined Chemotherapy Protocols","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D001215","descriptor_name":"Asparaginase","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D003841","descriptor_name":"Deoxycytidine","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D003841","descriptor_name":"Deoxycytidine","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D003841","descriptor_name":"Deoxycytidine","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D007211","descriptor_name":"Indoles","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D011092","descriptor_name":"Polyethylene Glycols","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D011804","descriptor_name":"Quinolines","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D054391","descriptor_name":"Lymphoma, Extranodal NK-T-Cell","qualifier_ui":"Q000175","qualifier_name":"diagnosis","is_major_topic":true},{"descriptor_ui":"D054391","descriptor_name":"Lymphoma, Extranodal NK-T-Cell","qualifier_ui":"Q000175","qualifier_name":"diagnosis","is_major_topic":true},{"descriptor_ui":"D054391","descriptor_name":"Lymphoma, Extranodal NK-T-Cell","qualifier_ui":"Q000175","qualifier_name":"diagnosis","is_major_topic":true},{"descriptor_ui":"D061067","descriptor_name":"Antibodies, Monoclonal, Humanized","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false}],"locations_count":2,"locations":[{"id":"doi:10.1002/ajh.26922","doi":"https://doi.org/10.1002/ajh.26922","is_oa":true,"landing_page_url":"https://doi.org/10.1002/ajh.26922","pdf_url":"https://onlinelibrary.wiley.com/doi/pdfdirect/10.1002/ajh.26922","source":{"id":"https://openalex.org/S199810014","display_name":"American Journal of Hematology","issn_l":"0361-8609","issn":["0361-8609","1096-8652"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-b","doyens","jufo-2","ki-jl-2","medline","norway-1","poland-140","russia-white-list-1"],"host_organization":"https://openalex.org/P4310320595","host_organization_name":"Wiley","host_organization_lineage":["https://openalex.org/P4310320595"],"host_organization_lineage_names":["Wiley"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"American Journal of Hematology","raw_type":"journal-article"},{"id":"pmid:36970971","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/36970971","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"American journal of hematology","raw_type":"Clinical Trial, Phase II"}],"best_oa_location":{"id":"doi:10.1002/ajh.26922","doi":"https://doi.org/10.1002/ajh.26922","is_oa":true,"landing_page_url":"https://doi.org/10.1002/ajh.26922","pdf_url":"https://onlinelibrary.wiley.com/doi/pdfdirect/10.1002/ajh.26922","source":{"id":"https://openalex.org/S199810014","display_name":"American Journal of Hematology","issn_l":"0361-8609","issn":["0361-8609","1096-8652"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-b","doyens","jufo-2","ki-jl-2","medline","norway-1","poland-140","russia-white-list-1"],"host_organization":"https://openalex.org/P4310320595","host_organization_name":"Wiley","host_organization_lineage":["https://openalex.org/P4310320595"],"host_organization_lineage_names":["Wiley"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"American Journal of Hematology","raw_type":"journal-article"},"sustainable_development_goals":[{"id":"https://metadata.un.org/sdg/3","display_name":"Good health and well-being","score":1.0}],"sustainable_development_goals_aurora":[{"id":"https://metadata.un.org/sdg/3","display_name":"Good health and well-being","score":0.6600000262260437}],"study_designs":[{"id":"https://openalex.org/study-designs/clinical-trial","display_name":"Clinical Trial"}],"awards":[{"id":"https://openalex.org/G3012746336","display_name":null,"funder_award_id":"2018ZX09734003","funder_id":"https://openalex.org/F4320329860","funder_display_name":"National Science and Technology Major Project"},{"id":"https://openalex.org/G4917725144","display_name":null,"funder_award_id":"81872902","funder_id":"https://openalex.org/F4320321001","funder_display_name":"National Natural Science Foundation of China"},{"id":"https://openalex.org/G7281738834","display_name":null,"funder_award_id":"82103579","funder_id":"https://openalex.org/F4320321001","funder_display_name":"National Natural Science Foundation of China"},{"id":"https://openalex.org/G7345485539","display_name":null,"funder_award_id":"82104273","funder_id":"https://openalex.org/F4320321001","funder_display_name":"National Natural Science Foundation of China"},{"id":"https://openalex.org/G7699715629","display_name":null,"funder_award_id":"82073917","funder_id":"https://openalex.org/F4320321001","funder_display_name":"National Natural Science Foundation of China"}],"funders":[{"id":"https://openalex.org/F4320321001","display_name":"National Natural Science Foundation of China","ror":"https://ror.org/01h0zpd94"},{"id":"https://openalex.org/F4320329860","display_name":"National Science and Technology Major Project","ror":null}],"has_content":{"grobid_xml":true,"pdf":true},"content_urls":{"pdf":"https://content.openalex.org/works/W4361007337.pdf","grobid_xml":"https://content.openalex.org/works/W4361007337.grobid-xml"},"referenced_works_count":58,"referenced_works":["https://openalex.org/W1755269379","https://openalex.org/W1828843757","https://openalex.org/W1831274761","https://openalex.org/W1964546077","https://openalex.org/W1972972039","https://openalex.org/W2002458206","https://openalex.org/W2013770941","https://openalex.org/W2022388117","https://openalex.org/W2026380928","https://openalex.org/W2040724113","https://openalex.org/W2076257589","https://openalex.org/W2078081404","https://openalex.org/W2101879498","https://openalex.org/W2103879368","https://openalex.org/W2104350866","https://openalex.org/W2107860361","https://openalex.org/W2108673054","https://openalex.org/W2119147717","https://openalex.org/W2160401270","https://openalex.org/W2253645956","https://openalex.org/W2328625719","https://openalex.org/W2333381803","https://openalex.org/W2519986995","https://openalex.org/W2586276931","https://openalex.org/W2765463268","https://openalex.org/W2788208686","https://openalex.org/W2793605704","https://openalex.org/W2801445543","https://openalex.org/W2808043936","https://openalex.org/W2886119834","https://openalex.org/W2892640821","https://openalex.org/W2902931487","https://openalex.org/W2939525597","https://openalex.org/W2941109595","https://openalex.org/W2943839194","https://openalex.org/W2964104024","https://openalex.org/W2967149286","https://openalex.org/W3000471804","https://openalex.org/W3009600316","https://openalex.org/W3011919019","https://openalex.org/W3022554601","https://openalex.org/W3036571927","https://openalex.org/W3037726457","https://openalex.org/W3096993764","https://openalex.org/W3116846005","https://openalex.org/W3118391493","https://openalex.org/W3125814085","https://openalex.org/W3126684855","https://openalex.org/W3126928179","https://openalex.org/W3130424028","https://openalex.org/W3181698670","https://openalex.org/W3210378023","https://openalex.org/W3211693992","https://openalex.org/W4212947378","https://openalex.org/W4213066621","https://openalex.org/W4281658290","https://openalex.org/W4281665682","https://openalex.org/W4282981116"],"related_works":["https://openalex.org/W2528167051","https://openalex.org/W4389728640","https://openalex.org/W2009096079","https://openalex.org/W2188607138","https://openalex.org/W4241786952","https://openalex.org/W3125059937","https://openalex.org/W2114699723","https://openalex.org/W2995532498","https://openalex.org/W4284988128","https://openalex.org/W3166594929"],"abstract_inverted_index":{"Abstract":[0],"Novel":[1],"highly":[2],"effective":[3],"and":[4,27,32,60,77,122,127,142,173,182,194,223,233],"low\u2010toxicity":[5],"combination":[6],"therapy":[7],"for":[8,69],"localized":[9],"extranodal":[10],"natural\u2010killer/T\u2010cell":[11],"lymphoma":[12],"(ENKTL)":[13],"remains":[14],"a":[15,160,247],"clinically":[16],"unmet":[17],"need.":[18],"This":[19],"phase":[20],"II":[21],"trial":[22],"(NCT03936452)":[23],"investigated":[24],"the":[25,88,169,212],"efficacy":[26,240],"safety":[28,249],"of":[29,81,119,163,209],"sintilimab,":[30,231],"anlotinib,":[31,232],"pegaspargase":[33,54,234],"sandwiched":[34,235],"with":[35,42,211,236,246],"radiotherapy":[36,76,237],"as":[37],"first\u2010line":[38],"treatment":[39,95],"in":[40,206,241],"patients":[41,48,131,245],"newly\u2010diagnosed":[43],"stage":[44],"I\u2013II":[45],"ENKTL.":[46],"The":[47,84,97,134,148,178],"received":[49],"sintilimab":[50],"200":[51],"mg":[52,63],"plus":[53],"2500":[55],"U/m2":[56],"on":[57,66],"day":[58],"1":[59],"anlotinib":[61],"12":[62],"once":[64],"daily":[65],"days":[67],"1\u201314":[68],"three":[70,79],"21\u2010day":[71],"cycles,":[72,110,117],"followed":[73],"by":[74],"intensity\u2010modulated":[75],"another":[78],"cycles":[80,141],"systemic":[82],"therapy.":[83],"primary":[85],"endpoint":[86],"was":[87,136,150],"complete":[89],"response":[90,112,120],"rate":[91,113],"(CRR)":[92],"after":[93,108,115,139,145,156],"six":[94,116,146,157],"cycles.":[96,147,158],"secondary":[98],"endpoints":[99],"included":[100],"progression\u2010free":[101],"survival":[102,105],"(PFS),":[103],"overall":[104,111],"(OS),":[106],"CRR":[107,135],"two":[109,140],"(ORR)":[114],"duration":[118],"(DOR),":[121],"safety.":[123],"Between":[124],"May":[125],"2019":[126],"July":[128],"2021,":[129],"58":[130],"were":[132,175,185],"enrolled.":[133],"55.1%":[137],"(27/49)":[138],"87.8%":[143,151],"(43/49)":[144],"ORR":[149],"(43/49;":[152],"95%":[153],"CI,":[154,167,188,192,197],"75.2\u201395.4)":[155],"After":[159],"median":[161,170],"follow\u2010up":[162],"22.5":[164],"months":[165],"(95%":[166,187,191,196],"20.4\u201324.6),":[168],"PFS,":[171,180],"OS,":[172,181],"DOR":[174,183],"not":[176],"reached.":[177],"2\u2010year":[179],"rates":[184],"87.6%":[186],"78.8\u201397.4),":[189],"97.9%":[190],"94.0\u2013100),":[193],"91.1%":[195],"83.2\u201399.8),":[198],"respectively.":[199],"Grade":[200],"3\u20134":[201],"treatment\u2010related":[202,227],"adverse":[203],"events":[204],"occurred":[205],"41.4%":[207],"(24/58)":[208],"patients,":[210],"most":[213],"common":[214],"being":[215],"hypertension":[216],"(15.5%),":[217],"hypertriglyceridemia":[218],"(8.6%),":[219],"oral":[220],"mucositis":[221],"(6.9%),":[222],"anemia":[224],"(5.2%).":[225],"No":[226],"deaths":[228],"occurred.":[229],"First\u2010line":[230],"demonstrated":[238],"promising":[239],"treatment\u2010na\u00efve":[242],"early\u2010stage":[243],"ENKTL":[244],"favorable":[248],"profile.":[250]},"counts_by_year":[{"year":2026,"cited_by_count":9},{"year":2025,"cited_by_count":8},{"year":2024,"cited_by_count":6},{"year":2023,"cited_by_count":2}],"updated_date":"2026-10-23T09:35:12.469056","created_date":"2023-03-30T00:00:00"}