{"id":"https://openalex.org/W43562266","doi":null,"title":"[Pathological gambling and Parkinson disease].","display_name":"[Pathological gambling and Parkinson disease].","publication_year":2008,"publication_date":"2008-09-01","ids":{"openalex":"https://openalex.org/W43562266","mag":"43562266","pmid":"https://pubmed.ncbi.nlm.nih.gov/18807938"},"language":"ja","primary_location":{"id":"pmid:18807938","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/18807938","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Brain and nerve = Shinkei kenkyu no shinpo","raw_type":"Case Reports"},"volume":null,"type":"article","is_traditional":true,"indexed_in":["pubmed"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5101479057","display_name":"Kenichi Fujimoto","orcid":"https://orcid.org/0000-0001-8907-4628","observed_orcids":["https://orcid.org/0000-0001-8907-4628"]},"institutions":[{"id":"https://openalex.org/I146500386","display_name":"Jichi Medical University","ror":"https://ror.org/010hz0g26","country_code":"JP","type":"education","lineage":["https://openalex.org/I146500386"]}],"countries":["JP"],"is_corresponding":true,"raw_author_name":"Ken-Ichi Fujimoto","raw_affiliation_strings":["Division of Neurology, Department of Medicine, Jichi Medical University, 3311-1 Yakushiji, Shimotsuke-shi, Tochigi 329-0498, Japan"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Division of Neurology, Department of Medicine, Jichi Medical University, 3311-1 Yakushiji, Shimotsuke-shi, Tochigi 329-0498, Japan","institution_ids":["https://openalex.org/I146500386"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":1,"corresponding_author_ids":["https://openalex.org/A5101479057"],"corresponding_institution_ids":["https://openalex.org/I146500386"],"apc_list":null,"apc_paid":null,"fwci":0.7115,"has_fulltext":false,"cited_by_count":6,"citation_normalized_percentile":{"value":0.74394203,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":88,"max":95},"biblio":{"volume":"60","issue":"9","first_page":"1039","last_page":"46"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T11705","display_name":"Gambling Behavior and Treatments","score":0.47269999980926514,"subfield":{"id":"https://openalex.org/subfields/3203","display_name":"Clinical Psychology"},"field":{"id":"https://openalex.org/fields/32","display_name":"Psychology"},"domain":{"id":"https://openalex.org/domains/2","display_name":"Social Sciences"}},"topics":[{"id":"https://openalex.org/T11705","display_name":"Gambling Behavior and Treatments","score":0.47269999980926514,"subfield":{"id":"https://openalex.org/subfields/3203","display_name":"Clinical Psychology"},"field":{"id":"https://openalex.org/fields/32","display_name":"Psychology"},"domain":{"id":"https://openalex.org/domains/2","display_name":"Social Sciences"}},{"id":"https://openalex.org/T10085","display_name":"Parkinson's Disease Mechanisms and Treatments","score":0.4424000084400177,"subfield":{"id":"https://openalex.org/subfields/2728","display_name":"Clinical Neurology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10919","display_name":"Deep Brain Stimulation and Movement Disorders","score":0.06210000067949295,"subfield":{"id":"https://openalex.org/subfields/2728","display_name":"Clinical Neurology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/gambling-disorder","display_name":"gambling addiction","score":1.0},{"id":"https://openalex.org/keywords/parkinson-s-disease","display_name":"Parkinson's disease","score":1.0},{"id":"https://openalex.org/keywords/dopamine-dysregulation-syndrome","display_name":"dopamine dysregulation syndrome","score":0.9639999866485596},{"id":"https://openalex.org/keywords/impulse-control-disorders","display_name":"impulse control disorders","score":0.871999979019165},{"id":"https://openalex.org/keywords/dopamine-agonists","display_name":"dopamine agonists","score":0.9010000228881836},{"id":"https://openalex.org/keywords/levodopa","display_name":"levodopa","score":0.8880000114440918},{"id":"https://openalex.org/keywords/pramipexole","display_name":"pramipexole","score":0.9639999866485596},{"id":"https://openalex.org/keywords/subthalamic-nucleus-deep-brain-stimulation","display_name":"subthalamic nucleus deep brain stimulation","score":0.9269999861717224},{"id":"https://openalex.org/keywords/punding","display_name":"punding","score":0.7379999756813049},{"id":"https://openalex.org/keywords/risk-factors","display_name":"risk factors","score":0.45899999141693115},{"id":"https://openalex.org/keywords/novelty-seeking","display_name":"novelty seeking","score":0.6890000104904175},{"id":"https://openalex.org/keywords/impulsivity","display_name":"impulsivity","score":0.8740000128746033},{"id":"https://openalex.org/keywords/alcohol-abuse","display_name":"alcohol abuse","score":0.7829999923706055}],"concepts":[{"id":"https://openalex.org/C2780304432","wikidata":"https://www.wikidata.org/wiki/Q300989","display_name":"Levodopa","level":4,"score":0.786112904548645},{"id":"https://openalex.org/C2781443782","wikidata":"https://www.wikidata.org/wiki/Q1201835","display_name":"Impulse control disorder","level":3,"score":0.7703917026519775},{"id":"https://openalex.org/C2777525119","wikidata":"https://www.wikidata.org/wiki/Q269111","display_name":"Apomorphine","level":4,"score":0.6659723520278931},{"id":"https://openalex.org/C137183658","wikidata":"https://www.wikidata.org/wiki/Q461076","display_name":"Dopaminergic","level":3,"score":0.6125648021697998},{"id":"https://openalex.org/C2779734285","wikidata":"https://www.wikidata.org/wiki/Q11085","display_name":"Parkinson's disease","level":3,"score":0.5762131810188293},{"id":"https://openalex.org/C513476851","wikidata":"https://www.wikidata.org/wiki/Q170304","display_name":"Dopamine","level":2,"score":0.5706267356872559},{"id":"https://openalex.org/C2778542668","wikidata":"https://www.wikidata.org/wiki/Q618076","display_name":"Deep brain stimulation","level":4,"score":0.5599116683006287},{"id":"https://openalex.org/C15744967","wikidata":"https://www.wikidata.org/wiki/Q9418","display_name":"Psychology","level":0,"score":0.5185014009475708},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.4622148871421814},{"id":"https://openalex.org/C2779989193","wikidata":"https://www.wikidata.org/wiki/Q421304","display_name":"Pramipexole","level":4,"score":0.4618225693702698},{"id":"https://openalex.org/C2908647359","wikidata":"https://www.wikidata.org/wiki/Q2625603","display_name":"Population","level":2,"score":0.4565529227256775},{"id":"https://openalex.org/C207886595","wikidata":"https://www.wikidata.org/wiki/Q1456138","display_name":"Pathological","level":2,"score":0.4551427960395813},{"id":"https://openalex.org/C2779134260","wikidata":"https://www.wikidata.org/wiki/Q12136","display_name":"Disease","level":2,"score":0.4453001022338867},{"id":"https://openalex.org/C48856860","wikidata":"https://www.wikidata.org/wiki/Q12029","display_name":"Addiction","level":2,"score":0.4273498058319092},{"id":"https://openalex.org/C2779088608","wikidata":"https://www.wikidata.org/wiki/Q267907","display_name":"Hypersexuality","level":3,"score":0.4103710949420929},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.39691776037216187},{"id":"https://openalex.org/C118552586","wikidata":"https://www.wikidata.org/wiki/Q7867","display_name":"Psychiatry","level":1,"score":0.3491464853286743},{"id":"https://openalex.org/C99454951","wikidata":"https://www.wikidata.org/wiki/Q932068","display_name":"Environmental health","level":1,"score":0.0}],"mesh":[{"descriptor_ui":"D000077487","descriptor_name":"Pramipexole","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D005715","descriptor_name":"Gambling","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D007174","descriptor_name":"Disruptive, Impulse Control, and Conduct Disorders","qualifier_ui":"Q000209","qualifier_name":"etiology","is_major_topic":true},{"descriptor_ui":"D007174","descriptor_name":"Disruptive, Impulse Control, and Conduct Disorders","qualifier_ui":"Q000453","qualifier_name":"epidemiology","is_major_topic":false},{"descriptor_ui":"D007174","descriptor_name":"Disruptive, Impulse Control, and Conduct Disorders","qualifier_ui":"Q000523","qualifier_name":"psychology","is_major_topic":true},{"descriptor_ui":"D007174","descriptor_name":"Disruptive, Impulse Control, and Conduct Disorders","qualifier_ui":"Q000628","qualifier_name":"therapy","is_major_topic":false},{"descriptor_ui":"D008297","descriptor_name":"Male","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008875","descriptor_name":"Middle Aged","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D010300","descriptor_name":"Parkinson Disease","qualifier_ui":"Q000628","qualifier_name":"therapy","is_major_topic":true},{"descriptor_ui":"D012306","descriptor_name":"Risk","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D018491","descriptor_name":"Dopamine Agonists","qualifier_ui":"Q000009","qualifier_name":"adverse effects","is_major_topic":true},{"descriptor_ui":"D018491","descriptor_name":"Dopamine Agonists","qualifier_ui":"Q000627","qualifier_name":"therapeutic use","is_major_topic":true},{"descriptor_ui":"D046690","descriptor_name":"Deep Brain Stimulation","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D050637","descriptor_name":"Receptors, Dopamine D3","qualifier_ui":"Q000187","qualifier_name":"drug effects","is_major_topic":false},{"descriptor_ui":"D052160","descriptor_name":"Benzothiazoles","qualifier_ui":"Q000009","qualifier_name":"adverse effects","is_major_topic":false},{"descriptor_ui":"D052160","descriptor_name":"Benzothiazoles","qualifier_ui":"Q000627","qualifier_name":"therapeutic use","is_major_topic":false}],"locations_count":2,"locations":[{"id":"pmid:18807938","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/18807938","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Brain and nerve = Shinkei kenkyu no shinpo","raw_type":"Case Reports"},{"id":"mag:43562266","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/18807938","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":null,"is_accepted":false,"is_published":false,"raw_source_name":"PubMed","raw_type":null}],"best_oa_location":null,"sustainable_development_goals":[{"id":"https://metadata.un.org/sdg/3","score":1.0,"display_name":"Good health and well-being"}],"study_designs":[],"awards":[],"funders":[],"has_content":{"pdf":false,"grobid_xml":false},"content_urls":null,"referenced_works_count":0,"referenced_works":[],"related_works":["https://openalex.org/W2005178489","https://openalex.org/W2322054165","https://openalex.org/W2030493565","https://openalex.org/W2189379683","https://openalex.org/W1978039564","https://openalex.org/W1980951225","https://openalex.org/W7070631866","https://openalex.org/W2013572056","https://openalex.org/W2021008779","https://openalex.org/W2033953309"],"abstract_inverted_index":{"Pathological":[0],"gambling":[1,15,98],"(PG)":[2],"is":[3,27,35,84,129,162,219,228,328],"defined":[4],"by":[5,131],"the":[6,50,79,89,123,132,171,200,203,223,270,320],"DSM":[7],"IV":[8],"criteria":[9],"as":[10,29,38,46,120],"inappropriate,":[11],"persistent,":[12],"and":[13,23,34,69,113,140,300],"maladaptive":[14],"behavior":[16],"that":[17,87],"has":[18,43,62,250],"repercussions":[19],"on":[20],"family,":[21],"personal,":[22],"professional":[24],"life.":[25],"It":[26],"classified":[28],"an":[30],"impulse":[31,110],"control":[32,111],"disorder":[33],"widely":[36],"understood":[37],"a":[39,47,73,179,255,282],"nonpharmacological":[40],"addiction.":[41],"PG":[42,59,92,108,144,158,183,214,246,265,315,324],"been":[44,63,251],"reported":[45,64,252],"complication":[48],"in":[49,60,78,93,100,152,160,222,245,258,262],"treatment":[51,327],"of":[52,58,75,91,122,135,157,173,182,187,195,206,209,225,275,285,289,297,306,319,323],"Parkinson":[53],"disease":[54],"(PD).":[55],"The":[56,154],"prevalence":[57,74,90],"PD":[61,95,101,161,290],"to":[65,72,107,164,170,191,239,254,314],"range":[66],"between":[67,202],"1.7":[68],"7%":[70],"compared":[71],"approximately":[76],"1%":[77],"general":[80],"population.":[81],"Though":[82,143],"there":[83],"no":[85],"survey":[86],"indicates":[88],"Japanese":[94],"patients,":[96,264],"problematic":[97],"behaviors":[99,112],"are":[102,118],"occasionally":[103],"observed.":[104],"In":[105],"addition":[106],"other":[109,185],"punding":[114],"(repetitive":[115],"stereotyped":[116],"behavior)":[117],"recognized":[119],"components":[121],"dopamine":[124,165,196],"dysregulation":[125],"syndrome":[126],"(DDS),":[127],"which":[128],"characterized":[130],"compulsive":[133],"use":[134],"dopaminergic":[136,259],"medications,":[137],"including":[138],"levodopa":[139,217,227],"subcutaneous":[141],"apomorphine.":[142],"can":[145],"occur":[146],"with":[147,216,311],"DDS":[148],"it":[149],"often":[150],"occurs":[151],"isolation.":[153],"vast":[155],"majority":[156,224],"seen":[159],"related":[163],"agonists":[166],"(DA).":[167],"With":[168],"regard":[169],"administration":[172],"oral":[174,188,210],"DA,":[175],"pramipexole":[176],"may":[177,280],"induce":[178],"higher":[180],"degree":[181],"than":[184],"types":[186],"DA":[189,211,326],"due":[190,253],"its":[192],"disproportionate":[193],"stimulation":[194,234],"D3":[197],"receptors.":[198],"However,":[199,261],"differences":[201],"observed":[204],"effects":[205],"various":[207],"classes":[208],"were":[212,303],"insignificant.":[213],"associated":[215],"mono-therapy":[218],"uncommon,":[220],"but":[221],"cases":[226],"co-prescribed.":[229],"Subthalamic":[230],"nucleus":[231],"deep":[232],"brain":[233],"(STN-DBS)":[235],"was":[236],"recently":[237],"introduced":[238],"treat":[240],"advanced":[241],"PD.":[242],"An":[243],"improvement":[244],"symptoms":[247],"following":[248,267],"STN-DBS":[249,268,277],"marked":[256],"decrease":[257],"medications.":[260],"some":[263],"developed":[266],"despite":[269],"significant":[271,304],"reduction":[272],"or":[273],"discontinuation":[274],"DA.":[276],"per":[278],"se":[279],"be":[281,317],"potential":[283,321],"initiator":[284],"PG.":[286,307],"Younger":[287],"age":[288],"onset,":[291],"novelty":[292],"seeking":[293],"personality":[294],"traits,":[295],"history":[296],"alcohol":[298],"abuse,":[299],"impulsivity":[301],"traits":[302],"predictors":[305],"Patients":[308],"especially":[309],"those":[310],"individual":[312],"susceptibility":[313],"should":[316],"warned":[318],"risks":[322],"before":[325],"initiated.":[329]},"counts_by_year":[{"year":2025,"cited_by_count":1},{"year":2014,"cited_by_count":1},{"year":2012,"cited_by_count":2}],"updated_date":"2026-11-04T10:54:05.112534","created_date":"2016-06-24T00:00:00"}