{"id":"https://openalex.org/W4353015411","doi":"https://doi.org/10.1002/jcb.30398","title":"Tyrosine phosphorylation of YAP\u20101 in biliary epithelial cells mediates posthepatectomy liver regeneration and is affected by serotonin","display_name":"Tyrosine phosphorylation of YAP\u20101 in biliary epithelial cells mediates posthepatectomy liver regeneration and is affected by serotonin","publication_year":2023,"publication_date":"2023-03-22","ids":{"openalex":"https://openalex.org/W4353015411","doi":"https://doi.org/10.1002/jcb.30398","pmid":"https://pubmed.ncbi.nlm.nih.gov/36946436","pmcid":"https://www.ncbi.nlm.nih.gov/pmc/articles/10200759"},"language":"en","primary_location":{"id":"doi:10.1002/jcb.30398","doi":"https://doi.org/10.1002/jcb.30398","is_oa":true,"landing_page_url":"http://dx.doi.org/10.1002/jcb.30398","pdf_url":"https://onlinelibrary.wiley.com/doi/pdfdirect/10.1002/jcb.30398","source":{"id":"https://openalex.org/S53807158","display_name":"Journal of Cellular Biochemistry","issn_l":"0730-2312","issn":["0730-2312","1097-4644"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-c","doyens","jufo-1","ki-jl-1","medline","norway-1","poland-100","russia-white-list-1"],"host_organization":"https://openalex.org/P4310320595","host_organization_name":"Wiley","host_organization_lineage":["https://openalex.org/P4310320595"],"host_organization_lineage_names":["Wiley"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Journal of Cellular Biochemistry","raw_type":"journal-article"},"volume":null,"type":"article","indexed_in":["crossref","pubmed"],"open_access":{"is_oa":true,"oa_status":"hybrid","oa_url":"https://onlinelibrary.wiley.com/doi/pdfdirect/10.1002/jcb.30398","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5005513529","display_name":"Patrick P. Starlinger","orcid":"https://orcid.org/0000-0002-4666-5337","observed_orcids":["https://orcid.org/0000-0002-4666-5337"]},"institutions":[{"id":"https://openalex.org/I1330342723","display_name":"Mayo Clinic","ror":"https://ror.org/02qp3tb03","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I1330342723"]},{"id":"https://openalex.org/I2802328216","display_name":"Vienna General Hospital","ror":"https://ror.org/05f0zr486","country_code":"AT","type":"healthcare","lineage":["https://openalex.org/I2802328216"]},{"id":"https://openalex.org/I76134821","display_name":"Medical University of Vienna","ror":"https://ror.org/05n3x4p02","country_code":"AT","type":"education","lineage":["https://openalex.org/I76134821"]}],"countries":["AT","US"],"is_corresponding":true,"raw_author_name":"Patrick Starlinger","raw_affiliation_strings":["Department of Surgery, Division of Hepatobiliary and Pancreatic Surgery, Mayo Clinic, Minnesota, Rochester, USA","Department of Surgery, General Hospital, Medical University of Vienna, Vienna, Austria"],"raw_orcid":"https://orcid.org/0000-0002-4666-5337","affiliations":[{"raw_affiliation_string":"Department of Surgery, Division of Hepatobiliary and Pancreatic Surgery, Mayo Clinic, Minnesota, Rochester, USA","institution_ids":["https://openalex.org/I1330342723"]},{"raw_affiliation_string":"Department of Surgery, General Hospital, Medical University of Vienna, Vienna, Austria","institution_ids":["https://openalex.org/I2802328216","https://openalex.org/I76134821"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5024985811","display_name":"Laura Brunnthaler","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I76134821","display_name":"Medical University of Vienna","ror":"https://ror.org/05n3x4p02","country_code":"AT","type":"education","lineage":["https://openalex.org/I76134821"]}],"countries":["AT"],"is_corresponding":false,"raw_author_name":"Laura Brunnthaler","raw_affiliation_strings":["Center of Physiology and Pharmacology, Institute of Vascular Biology and Thrombosis Research, Medical University of Vienna, Vienna, Austria"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Center of Physiology and Pharmacology, Institute of Vascular Biology and Thrombosis Research, Medical University of Vienna, Vienna, Austria","institution_ids":["https://openalex.org/I76134821"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5048034188","display_name":"Ryan D. Watkins","orcid":"https://orcid.org/0000-0002-7061-3238","observed_orcids":["https://orcid.org/0000-0002-7061-3238"]},"institutions":[{"id":"https://openalex.org/I1330342723","display_name":"Mayo Clinic","ror":"https://ror.org/02qp3tb03","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I1330342723"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Ryan Watkins","raw_affiliation_strings":["Department of Surgery, Division of Hepatobiliary and Pancreatic Surgery, Mayo Clinic, Minnesota, Rochester, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Surgery, Division of Hepatobiliary and Pancreatic Surgery, Mayo Clinic, Minnesota, Rochester, USA","institution_ids":["https://openalex.org/I1330342723"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5039124847","display_name":"David Pereyra","orcid":"https://orcid.org/0000-0001-6700-9163","observed_orcids":["https://orcid.org/0000-0001-6700-9163"]},"institutions":[{"id":"https://openalex.org/I2802328216","display_name":"Vienna General Hospital","ror":"https://ror.org/05f0zr486","country_code":"AT","type":"healthcare","lineage":["https://openalex.org/I2802328216"]},{"id":"https://openalex.org/I76134821","display_name":"Medical University of Vienna","ror":"https://ror.org/05n3x4p02","country_code":"AT","type":"education","lineage":["https://openalex.org/I76134821"]}],"countries":["AT"],"is_corresponding":false,"raw_author_name":"David Pereyra","raw_affiliation_strings":["Department of Surgery, General Hospital, Medical University of Vienna, Vienna, Austria"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Surgery, General Hospital, Medical University of Vienna, Vienna, Austria","institution_ids":["https://openalex.org/I2802328216","https://openalex.org/I76134821"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5040826548","display_name":"Judith Stift","orcid":"https://orcid.org/0000-0001-5334-9343","observed_orcids":["https://orcid.org/0000-0001-5334-9343"]},"institutions":[{"id":"https://openalex.org/I76134821","display_name":"Medical University of Vienna","ror":"https://ror.org/05n3x4p02","country_code":"AT","type":"education","lineage":["https://openalex.org/I76134821"]}],"countries":["AT"],"is_corresponding":false,"raw_author_name":"Judith Stift","raw_affiliation_strings":["Clinical Institute of Pathology, Medical University of Vienna, Vienna, Austria"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Clinical Institute of Pathology, Medical University of Vienna, Vienna, Austria","institution_ids":["https://openalex.org/I76134821"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5017087438","display_name":"Michaela Finsterbusch","orcid":"https://orcid.org/0000-0001-9470-4313","observed_orcids":["https://orcid.org/0000-0001-9470-4313"]},"institutions":[{"id":"https://openalex.org/I76134821","display_name":"Medical University of Vienna","ror":"https://ror.org/05n3x4p02","country_code":"AT","type":"education","lineage":["https://openalex.org/I76134821"]}],"countries":["AT"],"is_corresponding":false,"raw_author_name":"Michaela Finsterbusch","raw_affiliation_strings":["Center of Physiology and Pharmacology, Institute of Vascular Biology and Thrombosis Research, Medical University of Vienna, Vienna, Austria"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Center of Physiology and Pharmacology, Institute of Vascular Biology and Thrombosis Research, Medical University of Vienna, Vienna, Austria","institution_ids":["https://openalex.org/I76134821"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5053460957","display_name":"Jonas Santol","orcid":"https://orcid.org/0000-0002-8097-9735","observed_orcids":["https://orcid.org/0000-0002-8097-9735"]},"institutions":[{"id":"https://openalex.org/I2802328216","display_name":"Vienna General Hospital","ror":"https://ror.org/05f0zr486","country_code":"AT","type":"healthcare","lineage":["https://openalex.org/I2802328216"]},{"id":"https://openalex.org/I76134821","display_name":"Medical University of Vienna","ror":"https://ror.org/05n3x4p02","country_code":"AT","type":"education","lineage":["https://openalex.org/I76134821"]}],"countries":["AT"],"is_corresponding":false,"raw_author_name":"Jonas Santol","raw_affiliation_strings":["Department of Surgery, General Hospital, Medical University of Vienna, Vienna, Austria"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Surgery, General Hospital, Medical University of Vienna, Vienna, Austria","institution_ids":["https://openalex.org/I2802328216","https://openalex.org/I76134821"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5025262073","display_name":"Thomas Gruenberger","orcid":"https://orcid.org/0000-0002-2671-0540","observed_orcids":["https://orcid.org/0000-0002-2671-0540"]},"institutions":[{"id":"https://openalex.org/I109570744","display_name":"Sigmund Freud Privatuniversit\u00e4t Wien","ror":"https://ror.org/04hwbg047","country_code":"AT","type":"education","lineage":["https://openalex.org/I109570744"]}],"countries":["AT"],"is_corresponding":false,"raw_author_name":"Thomas Gruenberger","raw_affiliation_strings":["Department of Surgery, HPB Center, Viennese Health Network, Clinic Favoriten and Sigmund Freud Private University, Vienna, Austria"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Surgery, HPB Center, Viennese Health Network, Clinic Favoriten and Sigmund Freud Private University, Vienna, Austria","institution_ids":["https://openalex.org/I109570744"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5012863184","display_name":"Alice Assinger","orcid":"https://orcid.org/0000-0002-5670-5910","observed_orcids":["https://orcid.org/0000-0002-5670-5910"]},"institutions":[{"id":"https://openalex.org/I76134821","display_name":"Medical University of Vienna","ror":"https://ror.org/05n3x4p02","country_code":"AT","type":"education","lineage":["https://openalex.org/I76134821"]}],"countries":["AT"],"is_corresponding":false,"raw_author_name":"Alice Assinger","raw_affiliation_strings":["Center of Physiology and Pharmacology, Institute of Vascular Biology and Thrombosis Research, Medical University of Vienna, Vienna, Austria"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Center of Physiology and Pharmacology, Institute of Vascular Biology and Thrombosis Research, Medical University of Vienna, Vienna, Austria","institution_ids":["https://openalex.org/I76134821"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5064918059","display_name":"Rory L. Smoot","orcid":"https://orcid.org/0000-0001-8543-661X","observed_orcids":["https://orcid.org/0000-0001-8543-661X"]},"institutions":[{"id":"https://openalex.org/I1330342723","display_name":"Mayo Clinic","ror":"https://ror.org/02qp3tb03","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I1330342723"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Rory Smoot","raw_affiliation_strings":["Department of Biochemistry and Molecular Biology, Mayo Clinic, Minnesota, Rochester, USA","Department of Surgery, Division of Hepatobiliary and Pancreatic Surgery, Mayo Clinic, Minnesota, Rochester, USA"],"raw_orcid":"https://orcid.org/0000-0001-8543-661X","affiliations":[{"raw_affiliation_string":"Department of Biochemistry and Molecular Biology, Mayo Clinic, Minnesota, Rochester, USA","institution_ids":["https://openalex.org/I1330342723"]},{"raw_affiliation_string":"Department of Surgery, Division of Hepatobiliary and Pancreatic Surgery, Mayo Clinic, Minnesota, Rochester, USA","institution_ids":["https://openalex.org/I1330342723"]}]}],"institutions":[],"countries_distinct_count":2,"institutions_distinct_count":4,"corresponding_author_ids":["https://openalex.org/A5005513529"],"corresponding_institution_ids":["https://openalex.org/I1330342723","https://openalex.org/I2802328216","https://openalex.org/I76134821"],"apc_list":{"value":4640,"currency":"USD","value_usd":4640},"apc_paid":{"value":4640,"currency":"USD","value_usd":4640},"fwci":0.3907,"has_fulltext":true,"cited_by_count":3,"citation_normalized_percentile":{"value":0.56603774,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":88,"max":97},"biblio":{"volume":"124","issue":"5","first_page":"687","last_page":"700"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10966","display_name":"Liver physiology and pathology","score":0.9380000233650208,"subfield":{"id":"https://openalex.org/subfields/2721","display_name":"Hepatology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T10966","display_name":"Liver physiology and pathology","score":0.9380000233650208,"subfield":{"id":"https://openalex.org/subfields/2721","display_name":"Hepatology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T12065","display_name":"Hippo pathway signaling and YAP/TAZ","score":0.059700001031160355,"subfield":{"id":"https://openalex.org/subfields/1307","display_name":"Cell Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10999","display_name":"Organ Transplantation Techniques and Outcomes","score":0.00019999999494757503,"subfield":{"id":"https://openalex.org/subfields/2746","display_name":"Surgery"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/yap","display_name":"YAP","score":0.9850000143051147},{"id":"https://openalex.org/keywords/tyrosine-phosphorylation","display_name":"tyrosine phosphorylation","score":0.9919999837875366},{"id":"https://openalex.org/keywords/serotonin","display_name":"serotonin","score":0.8349999785423279},{"id":"https://openalex.org/keywords/liver-regeneration","display_name":"liver regeneration","score":0.9049999713897705},{"id":"https://openalex.org/keywords/cholangiocytes","display_name":"cholangiocytes","score":0.8539999723434448},{"id":"https://openalex.org/keywords/osteopontin","display_name":"osteopontin","score":0.9459999799728394},{"id":"https://openalex.org/keywords/partial-hepatectomy","display_name":"partial hepatectomy","score":0.9649999737739563},{"id":"https://openalex.org/keywords/selective-serotonin-reuptake-inhibitors","display_name":"selective serotonin reuptake inhibitors","score":0.9359999895095825},{"id":"https://openalex.org/keywords/taz","display_name":"TAZ","score":0.6010000109672546},{"id":"https://openalex.org/keywords/cytokeratin-19","display_name":"cytokeratin 19","score":0.7400000095367432}],"concepts":[{"id":"https://openalex.org/C11960822","wikidata":"https://www.wikidata.org/wiki/Q242736","display_name":"Phosphorylation","level":2,"score":0.7020223736763},{"id":"https://openalex.org/C2776795407","wikidata":"https://www.wikidata.org/wiki/Q19597761","display_name":"Liver regeneration","level":3,"score":0.6917310357093811},{"id":"https://openalex.org/C2777553839","wikidata":"https://www.wikidata.org/wiki/Q14330986","display_name":"Tyrosine phosphorylation","level":3,"score":0.6709751486778259},{"id":"https://openalex.org/C2780804394","wikidata":"https://www.wikidata.org/wiki/Q411994","display_name":"Osteopontin","level":2,"score":0.6205400824546814},{"id":"https://openalex.org/C171056886","wikidata":"https://www.wikidata.org/wiki/Q193119","display_name":"Regeneration (biology)","level":2,"score":0.5728222131729126},{"id":"https://openalex.org/C2779343474","wikidata":"https://www.wikidata.org/wiki/Q3109175","display_name":"Context (archaeology)","level":2,"score":0.4958594739437103},{"id":"https://openalex.org/C185592680","wikidata":"https://www.wikidata.org/wiki/Q2329","display_name":"Chemistry","level":0,"score":0.48034656047821045},{"id":"https://openalex.org/C134018914","wikidata":"https://www.wikidata.org/wiki/Q162606","display_name":"Endocrinology","level":1,"score":0.45320796966552734},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.4529617428779602},{"id":"https://openalex.org/C2776996007","wikidata":"https://www.wikidata.org/wiki/Q2399112","display_name":"Hepatocyte growth factor","level":3,"score":0.44499364495277405},{"id":"https://openalex.org/C502942594","wikidata":"https://www.wikidata.org/wiki/Q3421914","display_name":"Cancer research","level":1,"score":0.3571157455444336},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.32973477244377136},{"id":"https://openalex.org/C95444343","wikidata":"https://www.wikidata.org/wiki/Q7141","display_name":"Cell biology","level":1,"score":0.32285410165786743},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.21757689118385315},{"id":"https://openalex.org/C170493617","wikidata":"https://www.wikidata.org/wiki/Q208467","display_name":"Receptor","level":2,"score":0.11306595802307129},{"id":"https://openalex.org/C151730666","wikidata":"https://www.wikidata.org/wiki/Q7205","display_name":"Paleontology","level":1,"score":0.0}],"mesh":[{"descriptor_ui":"D000091102","descriptor_name":"YAP-Signaling Proteins","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000818","descriptor_name":"Animals","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D004847","descriptor_name":"Epithelial Cells","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008099","descriptor_name":"Liver","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D008099","descriptor_name":"Liver","qualifier_ui":"Q000601","qualifier_name":"surgery","is_major_topic":false},{"descriptor_ui":"D008115","descriptor_name":"Liver Regeneration","qualifier_ui":"Q000502","qualifier_name":"physiology","is_major_topic":true},{"descriptor_ui":"D010766","descriptor_name":"Phosphorylation","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D012701","descriptor_name":"Serotonin","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":true},{"descriptor_ui":"D012701","descriptor_name":"Serotonin","qualifier_ui":"Q000494","qualifier_name":"pharmacology","is_major_topic":true},{"descriptor_ui":"D014443","descriptor_name":"Tyrosine","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D049109","descriptor_name":"Cell Proliferation","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D051379","descriptor_name":"Mice","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false}],"locations_count":3,"locations":[{"id":"doi:10.1002/jcb.30398","doi":"https://doi.org/10.1002/jcb.30398","is_oa":true,"landing_page_url":"http://dx.doi.org/10.1002/jcb.30398","pdf_url":"https://onlinelibrary.wiley.com/doi/pdfdirect/10.1002/jcb.30398","source":{"id":"https://openalex.org/S53807158","display_name":"Journal of Cellular Biochemistry","issn_l":"0730-2312","issn":["0730-2312","1097-4644"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-c","doyens","jufo-1","ki-jl-1","medline","norway-1","poland-100","russia-white-list-1"],"host_organization":"https://openalex.org/P4310320595","host_organization_name":"Wiley","host_organization_lineage":["https://openalex.org/P4310320595"],"host_organization_lineage_names":["Wiley"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Journal of Cellular Biochemistry","raw_type":"journal-article"},{"id":"pmid:36946436","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/36946436","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Journal of cellular biochemistry","raw_type":"Journal Article"},{"id":"pmh:oai:pubmedcentral.nih.gov:10200759","doi":null,"is_oa":true,"landing_page_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/10200759","pdf_url":"https://pmc.ncbi.nlm.nih.gov/articles/PMC10200759/pdf/nihms-1886077.pdf","source":{"id":"https://openalex.org/S2764455111","display_name":"PubMed Central","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":"other-oa","license_id":"https://openalex.org/licenses/other-oa","version":"acceptedVersion","is_accepted":true,"is_published":false,"raw_source_name":"J Cell Biochem","raw_type":"Text"}],"best_oa_location":{"id":"doi:10.1002/jcb.30398","doi":"https://doi.org/10.1002/jcb.30398","is_oa":true,"landing_page_url":"http://dx.doi.org/10.1002/jcb.30398","pdf_url":"https://onlinelibrary.wiley.com/doi/pdfdirect/10.1002/jcb.30398","source":{"id":"https://openalex.org/S53807158","display_name":"Journal of Cellular Biochemistry","issn_l":"0730-2312","issn":["0730-2312","1097-4644"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-c","doyens","jufo-1","ki-jl-1","medline","norway-1","poland-100","russia-white-list-1"],"host_organization":"https://openalex.org/P4310320595","host_organization_name":"Wiley","host_organization_lineage":["https://openalex.org/P4310320595"],"host_organization_lineage_names":["Wiley"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Journal of Cellular Biochemistry","raw_type":"journal-article"},"sustainable_development_goals":[{"score":0.9537000060081482,"id":"https://metadata.un.org/sdg/3","display_name":"Good health and well-being"}],"study_designs":[],"awards":[{"id":"https://openalex.org/G5699680360","display_name":"The theranostic potential of microRNAs in liver regeneration","funder_award_id":"P 32064","funder_id":"https://openalex.org/F4320321181","funder_display_name":"Austrian Science Fund"},{"id":"https://openalex.org/G5768089964","display_name":"Novel coagulation-dependent mechanisms of liver regeneration to detect and prevent liver dysfunction after partial hepatectomy","funder_award_id":"R01DK122813","funder_id":"https://openalex.org/F4320337357","funder_display_name":"National Institute of Diabetes and Digestive and Kidney Diseases"},{"id":"https://openalex.org/G8881131664","display_name":"Bacteria and Lichens","funder_award_id":"P 19098","funder_id":"https://openalex.org/F4320321181","funder_display_name":"Austrian Science Fund"}],"funders":[{"id":"https://openalex.org/F4320321181","display_name":"Austrian Science Fund","ror":"https://ror.org/013tf3c58"},{"id":"https://openalex.org/F4320332161","display_name":"National Institutes of Health","ror":"https://ror.org/01cwqze88"},{"id":"https://openalex.org/F4320337357","display_name":"National Institute of Diabetes and Digestive and Kidney Diseases","ror":"https://ror.org/00adh9b73"}],"has_content":{"grobid_xml":true,"pdf":true},"content_urls":{"pdf":"https://content.openalex.org/works/W4353015411.pdf","grobid_xml":"https://content.openalex.org/works/W4353015411.grobid-xml"},"referenced_works_count":54,"referenced_works":["https://openalex.org/W1235619914","https://openalex.org/W1767917618","https://openalex.org/W1906251018","https://openalex.org/W1906510709","https://openalex.org/W1940255321","https://openalex.org/W1978367598","https://openalex.org/W1989969354","https://openalex.org/W2007486557","https://openalex.org/W2030102531","https://openalex.org/W2033089307","https://openalex.org/W2045164759","https://openalex.org/W2062080733","https://openalex.org/W2069391261","https://openalex.org/W2070495192","https://openalex.org/W2076981447","https://openalex.org/W2090165963","https://openalex.org/W2092679286","https://openalex.org/W2101418562","https://openalex.org/W2110705719","https://openalex.org/W2132801501","https://openalex.org/W2134034445","https://openalex.org/W2134541063","https://openalex.org/W2140380685","https://openalex.org/W2159322258","https://openalex.org/W2164508226","https://openalex.org/W2170837135","https://openalex.org/W2281925357","https://openalex.org/W2440502547","https://openalex.org/W2512544075","https://openalex.org/W2560398235","https://openalex.org/W2586847824","https://openalex.org/W2593352412","https://openalex.org/W2730289288","https://openalex.org/W2747554157","https://openalex.org/W2769784848","https://openalex.org/W2774644059","https://openalex.org/W2808032803","https://openalex.org/W2888562652","https://openalex.org/W2901753855","https://openalex.org/W2921458707","https://openalex.org/W2921783097","https://openalex.org/W2954463691","https://openalex.org/W2980784802","https://openalex.org/W3014840219","https://openalex.org/W3047433286","https://openalex.org/W3083951278","https://openalex.org/W3088941414","https://openalex.org/W3093436712","https://openalex.org/W3096901923","https://openalex.org/W3125777536","https://openalex.org/W3180283012","https://openalex.org/W3192557662","https://openalex.org/W4200196284","https://openalex.org/W4244147270"],"related_works":["https://openalex.org/W3199420309","https://openalex.org/W2888562652","https://openalex.org/W3140100413","https://openalex.org/W2980784802","https://openalex.org/W4283661551","https://openalex.org/W7214213019","https://openalex.org/W2045164759","https://openalex.org/W2063053815","https://openalex.org/W2895169946","https://openalex.org/W4385514744"],"abstract_inverted_index":{"Experimental":[0],"data":[1],"suggested":[2],"activation":[3,207],"of":[4,12,60,66,89,96,109,120,182,190],"yes-associated":[5],"protein":[6],"(YAP-1)":[7],"as":[8,102,104],"a":[9],"critical":[10,220],"regulator":[11],"liver":[13,176],"regeneration":[14],"(LR).":[15],"Serotonin":[16],"(5-HT)":[17],"promotes":[18],"LR":[19,34,45,61,110,123,156,183,191,222],"in":[20,115,128,167,174,204,223,234,243],"rodent":[21],"models":[22],"and":[23,55,68,80,141,169,210,225,245],"has":[24],"been":[25],"proposed":[26],"to":[27,218],"act":[28],"via":[29,208,240],"YAP-1.":[30],"How":[31],"5-HT":[32,42,67,148,202],"affects":[33,43],"is":[35],"incompletely":[36],"understood.":[37],"A":[38,86],"possible":[39],"mechanism":[40],"how":[41],"human":[44],"was":[46,98],"explored.":[47],"Sixty-one":[48],"patients":[49],"were":[50,62,71,82],"included.":[51],"Tissue":[52],"samples":[53],"prior":[54],"2":[56,105,178],"h":[57,106,179],"after":[58,107,124,180],"induction":[59,108,143,181],"collected.":[63],"Circulating":[64],"levels":[65,149,172],"osteopontin":[69],"(OPN)":[70],"assessed.":[72],"YAP-1,":[73],"its":[74,170,237],"phosphorylation":[75],"states,":[76],"cytokeratin":[77],"19":[78],"(CK-19)":[79],"OPN":[81,142,163,213],"assessed":[83],"using":[84],"immunofluorescence.":[85],"mouse":[87],"model":[88],"biliary":[90],"epithelial":[91],"cells":[92],"(BECs)":[93],"specific":[94,118],"deletion":[95,119],"YAP/TAZ":[97,121],"developed.":[99],"YAP-1":[100,140,153,166,193,206,216,241],"increased":[101,173,195,205,212],"early":[103],"(p":[111,184,196],"=":[112,158,161,185,197],"0.025)":[113],"predominantly":[114],"BECs.":[116],"BEC":[117],"reduced":[122],"70%":[125],"partial":[126],"hepatectomy":[127],"mice":[129,224],"(Ki67%,":[130],"p":[131,160],"<":[132],"0.001).":[133],"SSRI":[134],"treatment,":[135],"depleting":[136],"intra-platelet":[137],"5-HT,":[138,231],"abolished":[139],"upon":[144,155],"LR.":[145],"Portal":[146],"vein":[147,177],"correlated":[150],"with":[151,165,201],"intrahepatic":[152],"expression":[154],"(R":[157],"0.703,":[159],"0.035).":[162],"colocalized":[164],"BECs":[168,200,215,244],"circulating":[171],"the":[175,188],"0.017).":[186],"In":[187],"context":[189],"tyrosine-phosphorylated":[192],"significantly":[194],"0.042).":[198],"Stimulating":[199],"resulted":[203],"tyrosine-phosphorylation":[209,242],"subsequently":[211],"expression.":[214],"appears":[217],"be":[219],"for":[221],"humans.":[226],"Our":[227],"evidence":[228],"suggests":[229],"that":[230],"at":[232],"least":[233],"part,":[235],"exerts":[236],"pro-regenerative":[238],"effects":[239],"subsequent":[246],"OPN-dependent":[247],"paracrine":[248],"immunomodulation.":[249]},"counts_by_year":[{"year":2026,"cited_by_count":2},{"year":2023,"cited_by_count":1}],"updated_date":"2026-11-04T10:54:05.112534","created_date":"2023-03-23T00:00:00"}
