{"id":"https://openalex.org/W4323906406","doi":"https://doi.org/10.1051/bioconf/20235802002","title":"Investigation of probiotic properties of Lactobacillus helveticus 2/20 isolated from rose blossom of Rosa damascena Mill.","display_name":"Investigation of probiotic properties of Lactobacillus helveticus 2/20 isolated from rose blossom of Rosa damascena Mill.","publication_year":2023,"publication_date":"2023-01-01","ids":{"openalex":"https://openalex.org/W4323906406","doi":"https://doi.org/10.1051/bioconf/20235802002"},"language":"en","primary_location":{"id":"doi:10.1051/bioconf/20235802002","doi":"https://doi.org/10.1051/bioconf/20235802002","is_oa":true,"landing_page_url":"https://doi.org/10.1051/bioconf/20235802002","pdf_url":"https://www.bio-conferences.org/articles/bioconf/pdf/2023/03/bioconf_foset22_02002.pdf","source":{"id":"https://openalex.org/S4210168758","display_name":"BIO Web of Conferences","issn_l":"2117-4458","issn":["2117-4458","2273-1709"],"is_oa":true,"is_in_doaj":true,"is_core":false,"listed_in":["ddh","doaj","norway-1"],"host_organization":"https://openalex.org/P4310319748","host_organization_name":"EDP Sciences","host_organization_lineage":["https://openalex.org/P4310319748","https://openalex.org/P4310319982"],"host_organization_lineage_names":["EDP Sciences","Science Press"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"BIO Web of Conferences","raw_type":"journal-article"},"volume":null,"type":"conference-paper","is_traditional":true,"indexed_in":["crossref","doaj"],"open_access":{"is_oa":true,"oa_status":"diamond","oa_url":"https://www.bio-conferences.org/articles/bioconf/pdf/2023/03/bioconf_foset22_02002.pdf","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5052786086","display_name":"Rositsa Stefanova Denkova-Kostova","orcid":"https://orcid.org/0000-0001-9727-235X","observed_orcids":["https://orcid.org/0000-0001-9727-235X"]},"institutions":[{"id":"https://openalex.org/I4210086451","display_name":"University of Food Technologies","ror":"https://ror.org/0014fb593","country_code":"BG","type":"education","lineage":["https://openalex.org/I4210086451"]}],"countries":["BG"],"is_corresponding":false,"raw_author_name":"Rositsa Denkova-Kostova","raw_affiliation_strings":["Department of Biochemistry and Molecular Biology, Technological Faculty, University of Food Technologies, 4002, Plovdiv, Bulgaria"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Biochemistry and Molecular Biology, Technological Faculty, University of Food Technologies, 4002, Plovdiv, Bulgaria","institution_ids":["https://openalex.org/I4210086451"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5065907302","display_name":"Bogdan Georgiev Goranov","orcid":"https://orcid.org/0000-0001-7173-7243","observed_orcids":["https://orcid.org/0000-0001-7173-7243","https://orcid.org/0000-0002-5836-4136"]},"institutions":[{"id":"https://openalex.org/I4210086451","display_name":"University of Food Technologies","ror":"https://ror.org/0014fb593","country_code":"BG","type":"education","lineage":["https://openalex.org/I4210086451"]}],"countries":["BG"],"is_corresponding":false,"raw_author_name":"Bogdan Goranov","raw_affiliation_strings":["Department of Microbiology, Technological Faculty, University of Food Technologies, 4002, Plovdiv, Bulgaria"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Microbiology, Technological Faculty, University of Food Technologies, 4002, Plovdiv, Bulgaria","institution_ids":["https://openalex.org/I4210086451"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5088624015","display_name":"Teodora Tomova","orcid":"https://orcid.org/0000-0002-2138-2795","observed_orcids":["https://orcid.org/0000-0002-2138-2795"]},"institutions":[{"id":"https://openalex.org/I4210086451","display_name":"University of Food Technologies","ror":"https://ror.org/0014fb593","country_code":"BG","type":"education","lineage":["https://openalex.org/I4210086451"]}],"countries":["BG"],"is_corresponding":false,"raw_author_name":"Teodora Tomova","raw_affiliation_strings":["Department of Microbiology, Technological Faculty, University of Food Technologies, 4002, Plovdiv, Bulgaria"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Microbiology, Technological Faculty, University of Food Technologies, 4002, Plovdiv, Bulgaria","institution_ids":["https://openalex.org/I4210086451"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5028744447","display_name":"Velichka Yanakieva","orcid":"https://orcid.org/0000-0003-0862-6238","observed_orcids":["https://orcid.org/0000-0003-0862-6238"]},"institutions":[{"id":"https://openalex.org/I4210086451","display_name":"University of Food Technologies","ror":"https://ror.org/0014fb593","country_code":"BG","type":"education","lineage":["https://openalex.org/I4210086451"]}],"countries":["BG"],"is_corresponding":false,"raw_author_name":"Velichka Yanakieva","raw_affiliation_strings":["Department of Microbiology, Technological Faculty, University of Food Technologies, 4002, Plovdiv, Bulgaria"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Microbiology, Technological Faculty, University of Food Technologies, 4002, Plovdiv, Bulgaria","institution_ids":["https://openalex.org/I4210086451"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5069755597","display_name":"Denica Eliyanova Blazheva","orcid":"https://orcid.org/0000-0002-4939-881X","observed_orcids":["https://orcid.org/0000-0002-4939-881X"]},"institutions":[{"id":"https://openalex.org/I4210086451","display_name":"University of Food Technologies","ror":"https://ror.org/0014fb593","country_code":"BG","type":"education","lineage":["https://openalex.org/I4210086451"]}],"countries":["BG"],"is_corresponding":false,"raw_author_name":"Denica Blazheva","raw_affiliation_strings":["Department of Microbiology, Technological Faculty, University of Food Technologies, 4002, Plovdiv, Bulgaria"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Microbiology, Technological Faculty, University of Food Technologies, 4002, Plovdiv, Bulgaria","institution_ids":["https://openalex.org/I4210086451"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5112300274","display_name":"Zapryana Rangelova Denkova","orcid":"https://orcid.org/0000-0003-2498-9741","observed_orcids":["https://orcid.org/0000-0003-2498-9741"]},"institutions":[{"id":"https://openalex.org/I4210086451","display_name":"University of Food Technologies","ror":"https://ror.org/0014fb593","country_code":"BG","type":"education","lineage":["https://openalex.org/I4210086451"]}],"countries":["BG"],"is_corresponding":false,"raw_author_name":"Zapryana Denkova","raw_affiliation_strings":["Department of Biochemistry and Molecular Biology, Technological Faculty, University of Food Technologies, 4002, Plovdiv, Bulgaria"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Biochemistry and Molecular Biology, Technological Faculty, University of Food Technologies, 4002, Plovdiv, Bulgaria","institution_ids":["https://openalex.org/I4210086451"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5034852454","display_name":"Georgi Atanasov Kostov","orcid":"https://orcid.org/0000-0003-4661-0421","observed_orcids":["https://orcid.org/0000-0003-4661-0421"]},"institutions":[{"id":"https://openalex.org/I4210086451","display_name":"University of Food Technologies","ror":"https://ror.org/0014fb593","country_code":"BG","type":"education","lineage":["https://openalex.org/I4210086451"]}],"countries":["BG"],"is_corresponding":false,"raw_author_name":"Georgi Kostov","raw_affiliation_strings":["Department of Technology of Wine and Beer, Technological Faculty, University of Food Technologies, 4002, Plovdiv, Bulgaria"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Technology of Wine and Beer, Technological Faculty, University of Food Technologies, 4002, Plovdiv, Bulgaria","institution_ids":["https://openalex.org/I4210086451"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":1,"corresponding_author_ids":[],"corresponding_institution_ids":["https://openalex.org/I4210086451"],"apc_list":null,"apc_paid":null,"fwci":6.0259,"has_fulltext":true,"cited_by_count":7,"citation_normalized_percentile":{"value":0.96515957,"is_in_top_1_percent":false,"is_in_top_10_percent":true},"cited_by_percentile_year":{"min":88,"max":97},"biblio":{"volume":"58","issue":null,"first_page":"02002","last_page":"02002"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10141","display_name":"Probiotics and Fermented Foods","score":1.0,"subfield":{"id":"https://openalex.org/subfields/1106","display_name":"Food Science"},"field":{"id":"https://openalex.org/fields/11","display_name":"Agricultural and Biological Sciences"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T10141","display_name":"Probiotics and Fermented Foods","score":1.0,"subfield":{"id":"https://openalex.org/subfields/1106","display_name":"Food Science"},"field":{"id":"https://openalex.org/fields/11","display_name":"Agricultural and Biological Sciences"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10428","display_name":"Reproductive tract infections research","score":0.0,"subfield":{"id":"https://openalex.org/subfields/2404","display_name":"Microbiology"},"field":{"id":"https://openalex.org/fields/24","display_name":"Immunology and Microbiology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T14438","display_name":"Advanced Scientific Research Methods","score":0.0,"subfield":{"id":"https://openalex.org/subfields/1106","display_name":"Food Science"},"field":{"id":"https://openalex.org/fields/11","display_name":"Agricultural and Biological Sciences"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/lactobacillus-helveticus","display_name":"Lactobacillus helveticus","score":0.996999979019165},{"id":"https://openalex.org/keywords/probiotics","display_name":"probiotics","score":0.6869999766349792},{"id":"https://openalex.org/keywords/rosa-damascena","display_name":"Rosa damascena","score":0.9900000095367432},{"id":"https://openalex.org/keywords/antimicrobial-activity","display_name":"antimicrobial activity","score":0.9459999799728394},{"id":"https://openalex.org/keywords/gastrointestinal-survival","display_name":"gastrointestinal survival","score":0.6299999952316284},{"id":"https://openalex.org/keywords/bile-salt-tolerance","display_name":"bile salt tolerance","score":0.7509999871253967},{"id":"https://openalex.org/keywords/bioreactor-culture","display_name":"bioreactor cultivation","score":0.7689999938011169},{"id":"https://openalex.org/keywords/freeze-drying","display_name":"freeze-drying","score":0.9190000295639038},{"id":"https://openalex.org/keywords/functional-foods","display_name":"functional foods","score":0.6480000019073486},{"id":"https://openalex.org/keywords/foodborne-illness","display_name":"food poisoning","score":0.4490000009536743}],"concepts":[{"id":"https://openalex.org/C2776030290","wikidata":"https://www.wikidata.org/wiki/Q142378","display_name":"Lactobacillus helveticus","level":4,"score":0.9697294235229492},{"id":"https://openalex.org/C2780255968","wikidata":"https://www.wikidata.org/wiki/Q1816730","display_name":"Probiotic","level":3,"score":0.8005886077880859},{"id":"https://openalex.org/C2775907625","wikidata":"https://www.wikidata.org/wiki/Q578904","display_name":"Rosa \u00d7 damascena","level":3,"score":0.795184314250946},{"id":"https://openalex.org/C31903555","wikidata":"https://www.wikidata.org/wiki/Q1637030","display_name":"Food science","level":1,"score":0.6242398023605347},{"id":"https://openalex.org/C100544194","wikidata":"https://www.wikidata.org/wiki/Q41760","display_name":"Fermentation","level":2,"score":0.6171613931655884},{"id":"https://openalex.org/C168170006","wikidata":"https://www.wikidata.org/wiki/Q864699","display_name":"Bioreactor","level":2,"score":0.5085254907608032},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.47073113918304443},{"id":"https://openalex.org/C2778022156","wikidata":"https://www.wikidata.org/wiki/Q576145","display_name":"Strain (injury)","level":2,"score":0.46212124824523926},{"id":"https://openalex.org/C185592680","wikidata":"https://www.wikidata.org/wiki/Q2329","display_name":"Chemistry","level":0,"score":0.43316829204559326},{"id":"https://openalex.org/C42062724","wikidata":"https://www.wikidata.org/wiki/Q1209205","display_name":"16S ribosomal RNA","level":3,"score":0.42135581374168396},{"id":"https://openalex.org/C89423630","wikidata":"https://www.wikidata.org/wiki/Q7193","display_name":"Microbiology","level":1,"score":0.4018579125404358},{"id":"https://openalex.org/C2780206646","wikidata":"https://www.wikidata.org/wiki/Q1061596","display_name":"Lactobacillus","level":3,"score":0.37468278408050537},{"id":"https://openalex.org/C523546767","wikidata":"https://www.wikidata.org/wiki/Q10876","display_name":"Bacteria","level":2,"score":0.3310205042362213},{"id":"https://openalex.org/C59822182","wikidata":"https://www.wikidata.org/wiki/Q441","display_name":"Botany","level":1,"score":0.2465953528881073},{"id":"https://openalex.org/C105702510","wikidata":"https://www.wikidata.org/wiki/Q514","display_name":"Anatomy","level":1,"score":0.0},{"id":"https://openalex.org/C54355233","wikidata":"https://www.wikidata.org/wiki/Q7162","display_name":"Genetics","level":1,"score":0.0},{"id":"https://openalex.org/C2777278459","wikidata":"https://www.wikidata.org/wiki/Q170885","display_name":"Essential oil","level":2,"score":0.0}],"mesh":[],"locations_count":2,"locations":[{"id":"doi:10.1051/bioconf/20235802002","doi":"https://doi.org/10.1051/bioconf/20235802002","is_oa":true,"landing_page_url":"https://doi.org/10.1051/bioconf/20235802002","pdf_url":"https://www.bio-conferences.org/articles/bioconf/pdf/2023/03/bioconf_foset22_02002.pdf","source":{"id":"https://openalex.org/S4210168758","display_name":"BIO Web of Conferences","issn_l":"2117-4458","issn":["2117-4458","2273-1709"],"is_oa":true,"is_in_doaj":true,"is_core":false,"listed_in":["ddh","doaj","norway-1"],"host_organization":"https://openalex.org/P4310319748","host_organization_name":"EDP Sciences","host_organization_lineage":["https://openalex.org/P4310319748","https://openalex.org/P4310319982"],"host_organization_lineage_names":["EDP Sciences","Science Press"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"BIO Web of Conferences","raw_type":"journal-article"},{"id":"pmh:oai:doaj.org/article:6055935883bb47e1988f6a089d84685f","doi":null,"is_oa":true,"landing_page_url":"https://doaj.org/article/6055935883bb47e1988f6a089d84685f","pdf_url":null,"source":{"id":"https://openalex.org/S4306401280","display_name":"DOAJ (DOAJ: Directory of Open Access Journals)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by-sa","license_id":"https://openalex.org/licenses/cc-by-sa","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"BIO Web of Conferences, Vol 58, p 02002 (2023)","raw_type":"article"}],"best_oa_location":{"id":"doi:10.1051/bioconf/20235802002","doi":"https://doi.org/10.1051/bioconf/20235802002","is_oa":true,"landing_page_url":"https://doi.org/10.1051/bioconf/20235802002","pdf_url":"https://www.bio-conferences.org/articles/bioconf/pdf/2023/03/bioconf_foset22_02002.pdf","source":{"id":"https://openalex.org/S4210168758","display_name":"BIO Web of Conferences","issn_l":"2117-4458","issn":["2117-4458","2273-1709"],"is_oa":true,"is_in_doaj":true,"is_core":false,"listed_in":["ddh","doaj","norway-1"],"host_organization":"https://openalex.org/P4310319748","host_organization_name":"EDP Sciences","host_organization_lineage":["https://openalex.org/P4310319748","https://openalex.org/P4310319982"],"host_organization_lineage_names":["EDP Sciences","Science Press"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"BIO Web of Conferences","raw_type":"journal-article"},"sustainable_development_goals":[],"study_designs":[],"awards":[],"funders":[],"has_content":{"pdf":true,"grobid_xml":true},"content_urls":{"pdf":"https://content.openalex.org/works/W4323906406.pdf","grobid_xml":"https://content.openalex.org/works/W4323906406.grobid-xml"},"referenced_works_count":34,"referenced_works":["https://openalex.org/W1489000026","https://openalex.org/W1798817938","https://openalex.org/W1965065927","https://openalex.org/W1965326485","https://openalex.org/W1994954454","https://openalex.org/W1997062053","https://openalex.org/W2010360751","https://openalex.org/W2022518106","https://openalex.org/W2036289641","https://openalex.org/W2036565601","https://openalex.org/W2050714021","https://openalex.org/W2051940084","https://openalex.org/W2058160797","https://openalex.org/W2062236341","https://openalex.org/W2072505334","https://openalex.org/W2076403396","https://openalex.org/W2086758072","https://openalex.org/W2086772818","https://openalex.org/W2105790349","https://openalex.org/W2119172200","https://openalex.org/W2119255453","https://openalex.org/W2122398832","https://openalex.org/W2136931384","https://openalex.org/W2165623470","https://openalex.org/W2185564569","https://openalex.org/W2237146922","https://openalex.org/W2575763462","https://openalex.org/W2615884100","https://openalex.org/W2952193831","https://openalex.org/W2989931585","https://openalex.org/W3003934337","https://openalex.org/W3004228638","https://openalex.org/W4221072853","https://openalex.org/W4237595601"],"related_works":["https://openalex.org/W6940811279","https://openalex.org/W4410628610","https://openalex.org/W7138894786","https://openalex.org/W2014822901","https://openalex.org/W2360653478","https://openalex.org/W4407866696","https://openalex.org/W2942022556","https://openalex.org/W3092205115","https://openalex.org/W2749124580","https://openalex.org/W2043755122"],"abstract_inverted_index":{"A":[0],"Lactobacillus":[1,21],"strain":[2,55,134],"was":[3,14,52],"isolated":[4],"from":[5,187],"rose":[6],"blossom":[7],"of":[8,26,35,42,45,48,77,104,114,140,147,160,183,204,215],"Rosa":[9],"damascena":[10],"Mill.":[11],"and":[12,31,67,85,90,92,96,138,170,217],"it":[13,208],"identified":[15],"as":[16,98,100,192,194],"belonging":[17],"to":[18,106,189],"the":[19,24,36,74,78,102,130,141,145,151,161,171,178,184,201,213],"species":[20],"helveticus":[22,50,70,123,206],"by":[23],"application":[25],"physiological-biochemical":[27],"(API":[28],"50":[29],"CHL)":[30],"molecular-genetic":[32],"methods":[33],"(sequencing":[34],"16S":[37],"rRNA":[38],"gene).":[39],"The":[40,54,133,157],"presence":[41,103],"a":[43,111,166],"number":[44],"probiotic":[46,202],"properties":[47,203],"L.":[49,69,122,205],"2/20":[51,71,124],"investigated.":[53],"exhibited":[56],"high":[57],"antimicrobial":[58],"activity":[59],"against":[60],"pathogenic":[61],"microorganisms":[62],"that":[63,121],"cause":[64],"food":[65],"toxicoinfections":[66],"intoxications.":[68],"survived":[72],"in":[73,101,150,165,212],"simulated":[75],"conditions":[76],"gastrointestinal":[79],"tract":[80],"\u2013":[81],"pH":[82,87,93],"=":[83,88,94],"2":[84],"pepsin,":[86],"4.5":[89],"pancreatin":[91],"8":[95],"pancreatin,":[97],"well":[99,193],"up":[105,182],"0.3%":[107],"bile":[108],"salts,":[109],"retaining":[110],"significant":[112],"concentration":[113,146],"viable":[115],"cells.":[116],"It":[117],"has":[118],"been":[119],"shown":[120],"cells":[125,149],"begin":[126],"multiplying":[127],"after":[128],"removing":[129],"extreme":[131],"conditions.":[132],"allowed":[135],"bioreactor":[136,167],"cultivation":[137,163],"freeze-drying":[139],"obtained":[142],"concentrates,":[143],"with":[144,168],"active":[148],"lyophilic":[152],"preparations":[153],"exceeding":[154],"1012":[155],"cfu/g.":[156],"kinetic":[158],"parameters":[159],"batch":[162],"process":[164,186],"stirring":[169],"maximum":[172],"growth":[173],"rate":[174],"were":[175],"determined,":[176],"revealing":[177],"possibilities":[179],"for":[180],"scaling":[181],"fermentation":[185],"laboratory":[188],"industrial":[190],"conditions,":[191],"its":[195],"management.":[196],"After":[197],"further":[198],"research":[199],"on":[200],"2/20,":[207],"can":[209],"be":[210],"included":[211],"composition":[214],"probiotics":[216],"functional":[218],"foods.":[219]},"counts_by_year":[{"year":2026,"cited_by_count":1},{"year":2025,"cited_by_count":1},{"year":2024,"cited_by_count":1},{"year":2023,"cited_by_count":4}],"updated_date":"2026-11-07T11:25:07.637180","created_date":"2023-03-12T00:00:00"}