{"id":"https://openalex.org/W4322764477","doi":"https://doi.org/10.1055/a-2013-3008","title":"Antimicrobial Isoflavans and Other Metabolites of Dalea jamesii","display_name":"Antimicrobial Isoflavans and Other Metabolites of Dalea jamesii","publication_year":2023,"publication_date":"2023-03-02","ids":{"openalex":"https://openalex.org/W4322764477","doi":"https://doi.org/10.1055/a-2013-3008","pmid":"https://pubmed.ncbi.nlm.nih.gov/36863394"},"language":"en","primary_location":{"id":"doi:10.1055/a-2013-3008","doi":"https://doi.org/10.1055/a-2013-3008","is_oa":false,"landing_page_url":"https://doi.org/10.1055/a-2013-3008","pdf_url":null,"source":{"id":"https://openalex.org/S39653451","display_name":"Planta Medica","issn_l":"0032-0943","issn":["0032-0943","1439-0221"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-c","jufo-1","medline","norway-1","poland-100","russia-white-list-1"],"host_organization":"https://openalex.org/P4310320000","host_organization_name":"Thieme Medical Publishers (Germany)","host_organization_lineage":["https://openalex.org/P4310320000"],"host_organization_lineage_names":["Thieme Medical Publishers (Germany)"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Planta Medica","raw_type":"journal-article"},"volume":null,"type":"article","indexed_in":["crossref","pubmed"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5031539693","display_name":"Gil Belofsky","orcid":"https://orcid.org/0000-0002-2135-6714","observed_orcids":["https://orcid.org/0000-0002-2135-6714"]},"institutions":[{"id":"https://openalex.org/I29867402","display_name":"Central Washington University","ror":"https://ror.org/049c8eh51","country_code":"US","type":"education","lineage":["https://openalex.org/I29867402"]}],"countries":["US"],"is_corresponding":true,"raw_author_name":"Gil Belofsky","raw_affiliation_strings":["Department of Chemistry, Central Washington University, Ellensburg, Washington, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Chemistry, Central Washington University, Ellensburg, Washington, USA","institution_ids":["https://openalex.org/I29867402"]}]},{"author_position":"middle","author":{"id":null,"display_name":"Hyojin Ahn","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I29867402","display_name":"Central Washington University","ror":"https://ror.org/049c8eh51","country_code":"US","type":"education","lineage":["https://openalex.org/I29867402"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Hyojin Ahn","raw_affiliation_strings":["Department of Chemistry, Central Washington University, Ellensburg, Washington, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Chemistry, Central Washington University, Ellensburg, Washington, USA","institution_ids":["https://openalex.org/I29867402"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5030146842","display_name":"Maxwell Zapata","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I29867402","display_name":"Central Washington University","ror":"https://ror.org/049c8eh51","country_code":"US","type":"education","lineage":["https://openalex.org/I29867402"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Maxwell Zapata","raw_affiliation_strings":["Department of Chemistry, Central Washington University, Ellensburg, Washington, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Chemistry, Central Washington University, Ellensburg, Washington, USA","institution_ids":["https://openalex.org/I29867402"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5048762950","display_name":"Dominique Wilcox","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I29867402","display_name":"Central Washington University","ror":"https://ror.org/049c8eh51","country_code":"US","type":"education","lineage":["https://openalex.org/I29867402"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Dominique Wilcox","raw_affiliation_strings":["Department of Chemistry, Central Washington University, Ellensburg, Washington, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Chemistry, Central Washington University, Ellensburg, Washington, USA","institution_ids":["https://openalex.org/I29867402"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5078268367","display_name":"Christine E. Salomon","orcid":"https://orcid.org/0000-0003-4976-598X","observed_orcids":["https://orcid.org/0000-0003-4976-598X"]},"institutions":[{"id":"https://openalex.org/I130238516","display_name":"University of Minnesota","ror":"https://ror.org/017zqws13","country_code":"US","type":"education","lineage":["https://openalex.org/I130238516"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Christine E. Salomon","raw_affiliation_strings":["Center for Drug Design, University of Minnesota, Minneapolis, Minnesota, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Center for Drug Design, University of Minnesota, Minneapolis, Minnesota, USA","institution_ids":["https://openalex.org/I130238516"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5046933314","display_name":"Paul Clinton Spiegel","orcid":"https://orcid.org/0000-0001-7982-5424","observed_orcids":["https://orcid.org/0000-0001-7982-5424"]},"institutions":[{"id":"https://openalex.org/I52669646","display_name":"Western Washington University","ror":"https://ror.org/05wn7r715","country_code":"US","type":"education","lineage":["https://openalex.org/I52669646"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"P. Clint Spiegel","raw_affiliation_strings":["Department of Chemistry, Western Washington University, Bellingham, Washington, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Chemistry, Western Washington University, Bellingham, Washington, USA","institution_ids":["https://openalex.org/I52669646"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":3,"corresponding_author_ids":["https://openalex.org/A5031539693"],"corresponding_institution_ids":["https://openalex.org/I29867402"],"apc_list":null,"apc_paid":null,"fwci":0.2594,"has_fulltext":false,"cited_by_count":3,"citation_normalized_percentile":{"value":0.40363284,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":89,"max":95},"biblio":{"volume":"89","issue":"07","first_page":"754","last_page":"763"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T12257","display_name":"Bioactive natural compounds","score":0.9926999807357788,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T12257","display_name":"Bioactive natural compounds","score":0.9926999807357788,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T11613","display_name":"Phytochemistry and Biological Activities","score":0.006599999964237213,"subfield":{"id":"https://openalex.org/subfields/1110","display_name":"Plant Science"},"field":{"id":"https://openalex.org/fields/11","display_name":"Agricultural and Biological Sciences"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10252","display_name":"Microbial Natural Products and Biosynthesis","score":0.0003000000142492354,"subfield":{"id":"https://openalex.org/subfields/2736","display_name":"Pharmacology (medical)"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/flavones","display_name":"flavones","score":0.6890000104904175},{"id":"https://openalex.org/keywords/chromans","display_name":"chromans","score":0.9900000095367432},{"id":"https://openalex.org/keywords/phenolic-compounds","display_name":"phenolic compounds","score":0.7940000295639038},{"id":"https://openalex.org/keywords/antimicrobial-activity","display_name":"antimicrobial activity","score":0.9470000267028809},{"id":"https://openalex.org/keywords/methicillin-resistant-staphylococcus-aureus","display_name":"methicillin-resistant Staphylococcus aureus","score":0.9829999804496765},{"id":"https://openalex.org/keywords/vancomycin-resistant-enterococcus-faecalis","display_name":"vancomycin-resistant Enterococcus faecalis","score":0.9990000128746033},{"id":"https://openalex.org/keywords/cryptococcus-neoformans","display_name":"Cryptococcus neoformans","score":0.9990000128746033},{"id":"https://openalex.org/keywords/absolute-configuration","display_name":"absolute configuration","score":0.7630000114440918},{"id":"https://openalex.org/keywords/phytochemical-isolation","display_name":"phytochemical isolation","score":0.5440000295639038}],"concepts":[{"id":"https://openalex.org/C2779895986","wikidata":"https://www.wikidata.org/wiki/Q140014","display_name":"Enterococcus faecalis","level":4,"score":0.8554227352142334},{"id":"https://openalex.org/C4937899","wikidata":"https://www.wikidata.org/wiki/Q68541106","display_name":"Antimicrobial","level":2,"score":0.8218822479248047},{"id":"https://openalex.org/C2779489039","wikidata":"https://www.wikidata.org/wiki/Q188121","display_name":"Staphylococcus aureus","level":3,"score":0.7120145559310913},{"id":"https://openalex.org/C195475562","wikidata":"https://www.wikidata.org/wiki/Q1639139","display_name":"Phytochemical","level":2,"score":0.7091739177703857},{"id":"https://openalex.org/C2777893358","wikidata":"https://www.wikidata.org/wiki/Q131924","display_name":"Cryptococcus neoformans","level":2,"score":0.5881286263465881},{"id":"https://openalex.org/C133571119","wikidata":"https://www.wikidata.org/wiki/Q899102","display_name":"Circular dichroism","level":2,"score":0.5791221857070923},{"id":"https://openalex.org/C2780900450","wikidata":"https://www.wikidata.org/wiki/Q44448","display_name":"Fabaceae","level":2,"score":0.48899638652801514},{"id":"https://openalex.org/C89423630","wikidata":"https://www.wikidata.org/wiki/Q7193","display_name":"Microbiology","level":1,"score":0.47305646538734436},{"id":"https://openalex.org/C185592680","wikidata":"https://www.wikidata.org/wiki/Q2329","display_name":"Chemistry","level":0,"score":0.4405863285064697},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.41488727927207947},{"id":"https://openalex.org/C71240020","wikidata":"https://www.wikidata.org/wiki/Q186011","display_name":"Stereochemistry","level":1,"score":0.36063504219055176},{"id":"https://openalex.org/C523546767","wikidata":"https://www.wikidata.org/wiki/Q10876","display_name":"Bacteria","level":2,"score":0.23003515601158142},{"id":"https://openalex.org/C55493867","wikidata":"https://www.wikidata.org/wiki/Q7094","display_name":"Biochemistry","level":1,"score":0.20864510536193848},{"id":"https://openalex.org/C59822182","wikidata":"https://www.wikidata.org/wiki/Q441","display_name":"Botany","level":1,"score":0.20312324166297913},{"id":"https://openalex.org/C54355233","wikidata":"https://www.wikidata.org/wiki/Q7162","display_name":"Genetics","level":1,"score":0.0}],"mesh":[{"descriptor_ui":"D000890","descriptor_name":"Anti-Infective Agents","qualifier_ui":"Q000494","qualifier_name":"pharmacology","is_major_topic":true},{"descriptor_ui":"D000900","descriptor_name":"Anti-Bacterial Agents","qualifier_ui":"Q000737","qualifier_name":"chemistry","is_major_topic":false},{"descriptor_ui":"D005419","descriptor_name":"Flavonoids","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008826","descriptor_name":"Microbial Sensitivity Tests","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D010636","descriptor_name":"Phenols","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D010936","descriptor_name":"Plant Extracts","qualifier_ui":"Q000494","qualifier_name":"pharmacology","is_major_topic":true},{"descriptor_ui":"D014640","descriptor_name":"Vancomycin","qualifier_ui":"Q000494","qualifier_name":"pharmacology","is_major_topic":false},{"descriptor_ui":"D055624","descriptor_name":"Methicillin-Resistant Staphylococcus aureus","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false}],"locations_count":3,"locations":[{"id":"doi:10.1055/a-2013-3008","doi":"https://doi.org/10.1055/a-2013-3008","is_oa":false,"landing_page_url":"https://doi.org/10.1055/a-2013-3008","pdf_url":null,"source":{"id":"https://openalex.org/S39653451","display_name":"Planta Medica","issn_l":"0032-0943","issn":["0032-0943","1439-0221"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-c","jufo-1","medline","norway-1","poland-100","russia-white-list-1"],"host_organization":"https://openalex.org/P4310320000","host_organization_name":"Thieme Medical Publishers (Germany)","host_organization_lineage":["https://openalex.org/P4310320000"],"host_organization_lineage_names":["Thieme Medical Publishers (Germany)"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Planta Medica","raw_type":"journal-article"},{"id":"pmid:36863394","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/36863394","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Planta medica","raw_type":"Journal Article"},{"id":"pmh:oai:digitalcommons.cwu.edu:cotsfac-1882","doi":null,"is_oa":false,"landing_page_url":"http://ezp.lib.cwu.edu/login?url=http://dx.doi.org/10.1055/a-2013-3008","pdf_url":null,"source":{"id":"https://openalex.org/S4377196478","display_name":"ScholarWorks (Central Washington University)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I29867402","host_organization_name":"Central Washington University","host_organization_lineage":["https://openalex.org/I29867402"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"All Faculty Scholarship for the College of the Sciences","raw_type":"text"}],"best_oa_location":null,"sustainable_development_goals":[{"id":"https://metadata.un.org/sdg/3","score":0.5683000087738037,"display_name":"Good health and well-being"}],"study_designs":[],"awards":[],"funders":[],"has_content":{"grobid_xml":false,"pdf":false},"content_urls":null,"referenced_works_count":17,"referenced_works":["https://openalex.org/W26641785","https://openalex.org/W1964311657","https://openalex.org/W1980200511","https://openalex.org/W2018493950","https://openalex.org/W2316723189","https://openalex.org/W2319019866","https://openalex.org/W2329795777","https://openalex.org/W2375107433","https://openalex.org/W2911576468","https://openalex.org/W2949460701","https://openalex.org/W2952021066","https://openalex.org/W3043210472","https://openalex.org/W3126519621","https://openalex.org/W3127236674","https://openalex.org/W3180164387","https://openalex.org/W4212959311","https://openalex.org/W4242318543"],"related_works":["https://openalex.org/W4400799764","https://openalex.org/W4413109494","https://openalex.org/W7143401258","https://openalex.org/W2329795777","https://openalex.org/W4378084438","https://openalex.org/W4402401752","https://openalex.org/W2015638581","https://openalex.org/W2091367108","https://openalex.org/W2027630112","https://openalex.org/W2950708093"],"abstract_inverted_index":{"Abstract":[0],"The":[1,53,69],"phytochemical":[2],"investigation":[3],"of":[4,6,17,55,72],"extracts":[5],"Dalea":[7],"jamesii":[8],"root":[9],"and":[10,48,113,138],"aerial":[11],"portions":[12],"led":[13],"to":[14],"the":[15,56,117,122],"isolation":[16],"ten":[18],"phenolic":[19],"compounds.":[20],"Six":[21],"previously":[22],"undescribed":[23],"prenylated":[24],"isoflavans,":[25],"summarily":[26],"named":[27],"ormegans":[28],"A":[29],"\u2013":[30,33,74,84,103],"F":[31],"(1":[32],"6),":[34],"were":[35,59,76],"characterized,":[36],"along":[37],"with":[38],"two":[39],"new":[40,57],"arylbenzofurans":[41],"(7,":[42],"8),":[43],"a":[44,49],"known":[45,50],"flavone":[46],"(9),":[47],"chroman":[51],"(10).":[52],"structures":[54],"compounds":[58],"deduced":[60],"by":[61,65,78],"NMR":[62],"spectroscopy,":[63],"supported":[64],"HRESI":[66],"mass":[67],"spectrometry.":[68],"absolute":[70],"configurations":[71],"1":[73,83],"6":[75],"determined":[77],"circular":[79],"dichroism":[80],"spectroscopy.":[81],"Compounds":[82],"9":[85],"exhibited":[86],"in":[87],"vitro":[88],"antimicrobial":[89],"activities,":[90],"causing":[91],"98%":[92],"or":[93],"greater":[94],"growth":[95,128],"inhibition":[96,129],"at":[97,130],"concentrations":[98],"as":[99,101],"low":[100],"2.5":[102,131],"5.1":[104],"\u00b5M":[105],"against":[106,133],"methicillin-resistant":[107,135],"Staphylococcus":[108],"aureus,":[109],"vancomycin-resistant":[110,139],"Enterococcus":[111],"faecalis,":[112,141],"Cryptococcus":[114],"neoformans.":[115],"Interestingly,":[116],"most":[118],"active":[119,144],"compound":[120],"was":[121],"dimeric":[123],"arylbenzofuran":[124],"8":[125],"(>":[126],"90%":[127],"\u00b5M)":[132],"both":[134],"S.":[136],"aureus":[137],"E.":[140],"tenfold":[142],"more":[143],"than":[145],"its":[146],"corresponding":[147],"monomer":[148],"(7).":[149]},"counts_by_year":[{"year":2026,"cited_by_count":1},{"year":2025,"cited_by_count":1},{"year":2024,"cited_by_count":1}],"updated_date":"2026-11-04T10:54:05.112534","created_date":"2023-03-03T00:00:00"}