{"id":"https://openalex.org/W4322697114","doi":"https://doi.org/10.1007/bf03401655","title":"A Major Allergen of Lymphatic Filarial Nematodes Is a Parasite Homolog of the \u03b3-Glutamyl Transpeptidase","display_name":"A Major Allergen of Lymphatic Filarial Nematodes Is a Parasite Homolog of the \u03b3-Glutamyl Transpeptidase","publication_year":1996,"publication_date":"1996-11-01","ids":{"openalex":"https://openalex.org/W4322697114","doi":"https://doi.org/10.1007/bf03401655","mag":"161931260","pmid":"https://pubmed.ncbi.nlm.nih.gov/8972486","pmcid":"https://www.ncbi.nlm.nih.gov/pmc/articles/2230135"},"language":"en","primary_location":{"id":"doi:10.1007/bf03401655","doi":"https://doi.org/10.1007/bf03401655","is_oa":true,"landing_page_url":"https://doi.org/10.1007/bf03401655","pdf_url":"https://molmed.biomedcentral.com/track/pdf/10.1007/BF03401655","source":{"id":"https://openalex.org/S6769275","display_name":"Molecular Medicine","issn_l":"1076-1551","issn":["1076-1551","1528-3658"],"is_oa":false,"is_in_doaj":true,"is_core":true,"listed_in":["cwts-core","doaj","dongbi-d","doyens","jufo-1","ki-jl-1","medline","norway-1","oarl","poland-100","russia-white-list-1"],"host_organization":"https://openalex.org/P4310320256","host_organization_name":"BioMed Central","host_organization_lineage":["https://openalex.org/P4310320256","https://openalex.org/P4310319965"],"host_organization_lineage_names":["BioMed Central","Springer Nature"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Molecular Medicine","raw_type":"journal-article"},"volume":null,"type":"article","is_traditional":true,"indexed_in":["crossref","doaj","pubmed"],"open_access":{"is_oa":true,"oa_status":"bronze","oa_url":"https://molmed.biomedcentral.com/track/pdf/10.1007/BF03401655","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5046698145","display_name":"Edgar Lobos","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I158937107","display_name":"Swiss Tropical and Public Health Institute","ror":"https://ror.org/03adhka07","country_code":"CH","type":"facility","lineage":["https://openalex.org/I158937107"]}],"countries":["CH"],"is_corresponding":false,"raw_author_name":"Edgar Lobos","raw_affiliation_strings":["Department of Medical Parasitology, Swiss Tropical Institute, Socinstrasse 57, 4002, Basel, Switzerland"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Medical Parasitology, Swiss Tropical Institute, Socinstrasse 57, 4002, Basel, Switzerland","institution_ids":["https://openalex.org/I158937107"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5049880781","display_name":"Regina Zahn","orcid":"https://orcid.org/0000-0002-6703-6169","observed_orcids":["https://orcid.org/0000-0002-6703-6169"]},"institutions":[{"id":"https://openalex.org/I158937107","display_name":"Swiss Tropical and Public Health Institute","ror":"https://ror.org/03adhka07","country_code":"CH","type":"facility","lineage":["https://openalex.org/I158937107"]}],"countries":["CH"],"is_corresponding":false,"raw_author_name":"Regina Zahn","raw_affiliation_strings":["Department of Medical Parasitology, Swiss Tropical Institute, Socinstrasse 57, 4002, Basel, Switzerland"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Medical Parasitology, Swiss Tropical Institute, Socinstrasse 57, 4002, Basel, Switzerland","institution_ids":["https://openalex.org/I158937107"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5112144979","display_name":"N Weiss","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I158937107","display_name":"Swiss Tropical and Public Health Institute","ror":"https://ror.org/03adhka07","country_code":"CH","type":"facility","lineage":["https://openalex.org/I158937107"]}],"countries":["CH"],"is_corresponding":false,"raw_author_name":"Niklaus Weiss","raw_affiliation_strings":["Department of Medical Parasitology, Swiss Tropical Institute, Socinstrasse 57, 4002, Basel, Switzerland"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Medical Parasitology, Swiss Tropical Institute, Socinstrasse 57, 4002, Basel, Switzerland","institution_ids":["https://openalex.org/I158937107"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5063107764","display_name":"Thomas B. Nutman","orcid":"https://orcid.org/0000-0001-6887-4941","observed_orcids":["https://orcid.org/0000-0001-6887-4941"]},"institutions":[{"id":"https://openalex.org/I1299303238","display_name":"National Institutes of Health","ror":"https://ror.org/01cwqze88","country_code":"US","type":"government","lineage":["https://openalex.org/I1299022934","https://openalex.org/I1299303238"]},{"id":"https://openalex.org/I4210134534","display_name":"National Institute of Allergy and Infectious Diseases","ror":"https://ror.org/043z4tv69","country_code":"US","type":"facility","lineage":["https://openalex.org/I1299022934","https://openalex.org/I1299303238","https://openalex.org/I4210134534"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Thomas B. Nutman","raw_affiliation_strings":["Laboratory of Parasitic Diseases, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, Maryland, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Laboratory of Parasitic Diseases, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, Maryland, USA","institution_ids":["https://openalex.org/I1299303238","https://openalex.org/I4210134534"]}]}],"institutions":[],"countries_distinct_count":2,"institutions_distinct_count":3,"corresponding_author_ids":[],"corresponding_institution_ids":[],"apc_list":{"value":3190,"currency":"USD","value_usd":3190},"apc_paid":null,"fwci":0.3138,"has_fulltext":true,"cited_by_count":27,"citation_normalized_percentile":{"value":0.67614815,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":87,"max":95},"biblio":{"volume":"2","issue":"6","first_page":"712","last_page":"724"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T11702","display_name":"Parasitic Diseases Research and Treatment","score":0.9994999766349792,"subfield":{"id":"https://openalex.org/subfields/2725","display_name":"Infectious Diseases"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T11702","display_name":"Parasitic Diseases Research and Treatment","score":0.9994999766349792,"subfield":{"id":"https://openalex.org/subfields/2725","display_name":"Infectious Diseases"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10695","display_name":"Parasites and Host Interactions","score":9.999999747378752e-05,"subfield":{"id":"https://openalex.org/subfields/2405","display_name":"Parasitology"},"field":{"id":"https://openalex.org/fields/24","display_name":"Immunology and Microbiology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10823","display_name":"Research on Leishmaniasis Studies","score":0.0,"subfield":{"id":"https://openalex.org/subfields/2739","display_name":"Public Health, Environmental and Occupational Health"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/tropical-pulmonary-eosinophilia","display_name":"tropical eosinophilia","score":0.8989999890327454},{"id":"https://openalex.org/keywords/brugia-malayi","display_name":"Brugia malayi","score":0.9850000143051147},{"id":"https://openalex.org/keywords/gamma-glutamyl-transferase","display_name":"gamma-glutamyl transferase","score":0.9120000004768372},{"id":"https://openalex.org/keywords/molecular-mimicry","display_name":"molecular mimicry","score":0.7490000128746033},{"id":"https://openalex.org/keywords/lung-epithelial-cells","display_name":"lung epithelial cells","score":0.734000027179718},{"id":"https://openalex.org/keywords/glutathione-metabolism","display_name":"glutathione metabolism","score":0.7910000085830688},{"id":"https://openalex.org/keywords/cross-reactive-antibodies","display_name":"cross-reactive antibodies","score":0.45899999141693115}],"concepts":[{"id":"https://openalex.org/C2775848585","wikidata":"https://www.wikidata.org/wiki/Q139658","display_name":"Brugia malayi","level":4,"score":0.8694989681243896},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.7407212853431702},{"id":"https://openalex.org/C141105273","wikidata":"https://www.wikidata.org/wiki/Q79455","display_name":"Immunoglobulin E","level":3,"score":0.6413484215736389},{"id":"https://openalex.org/C159654299","wikidata":"https://www.wikidata.org/wiki/Q79460","display_name":"Antibody","level":2,"score":0.5910793542861938},{"id":"https://openalex.org/C153911025","wikidata":"https://www.wikidata.org/wiki/Q7202","display_name":"Molecular biology","level":1,"score":0.536461353302002},{"id":"https://openalex.org/C40767141","wikidata":"https://www.wikidata.org/wiki/Q285697","display_name":"Recombinant DNA","level":3,"score":0.4857959747314453},{"id":"https://openalex.org/C187882448","wikidata":"https://www.wikidata.org/wiki/Q283478","display_name":"Complementary DNA","level":3,"score":0.4764195382595062},{"id":"https://openalex.org/C203014093","wikidata":"https://www.wikidata.org/wiki/Q101929","display_name":"Immunology","level":1,"score":0.423876017332077},{"id":"https://openalex.org/C159047783","wikidata":"https://www.wikidata.org/wiki/Q7215","display_name":"Virology","level":1,"score":0.338550865650177},{"id":"https://openalex.org/C104317684","wikidata":"https://www.wikidata.org/wiki/Q7187","display_name":"Gene","level":2,"score":0.1784171760082245},{"id":"https://openalex.org/C55493867","wikidata":"https://www.wikidata.org/wiki/Q7094","display_name":"Biochemistry","level":1,"score":0.16442039608955383},{"id":"https://openalex.org/C2777629521","wikidata":"https://www.wikidata.org/wiki/Q815753","display_name":"Filariasis","level":3,"score":0.0880955159664154},{"id":"https://openalex.org/C165901193","wikidata":"https://www.wikidata.org/wiki/Q3129936","display_name":"Helminths","level":2,"score":0.08714070916175842}],"mesh":[{"descriptor_ui":"D000595","descriptor_name":"Amino Acid Sequence","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000818","descriptor_name":"Animals","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000947","descriptor_name":"Antigens, Helminth","qualifier_ui":"Q000276","qualifier_name":"immunology","is_major_topic":false},{"descriptor_ui":"D000947","descriptor_name":"Antigens, Helminth","qualifier_ui":"Q000737","qualifier_name":"chemistry","is_major_topic":true},{"descriptor_ui":"D001323","descriptor_name":"Autoantibodies","qualifier_ui":"Q000276","qualifier_name":"immunology","is_major_topic":false},{"descriptor_ui":"D001483","descriptor_name":"Base Sequence","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D003001","descriptor_name":"Cloning, Molecular","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D004605","descriptor_name":"Elephantiasis, Filarial","qualifier_ui":"Q000469","qualifier_name":"parasitology","is_major_topic":true},{"descriptor_ui":"D004802","descriptor_name":"Eosinophilia","qualifier_ui":"Q000469","qualifier_name":"parasitology","is_major_topic":true},{"descriptor_ui":"D004802","descriptor_name":"Eosinophilia","qualifier_ui":"Q000503","qualifier_name":"physiopathology","is_major_topic":false},{"descriptor_ui":"D005723","descriptor_name":"gamma-Glutamyltransferase","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D005723","descriptor_name":"gamma-Glutamyltransferase","qualifier_ui":"Q000737","qualifier_name":"chemistry","is_major_topic":true},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D007073","descriptor_name":"Immunoglobulin E","qualifier_ui":"Q000276","qualifier_name":"immunology","is_major_topic":false},{"descriptor_ui":"D007073","descriptor_name":"Immunoglobulin E","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D008565","descriptor_name":"Membrane Proteins","qualifier_ui":"Q000737","qualifier_name":"chemistry","is_major_topic":false},{"descriptor_ui":"D008969","descriptor_name":"Molecular Sequence Data","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D015152","descriptor_name":"Blotting, Northern","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D015153","descriptor_name":"Blotting, Western","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D017178","descriptor_name":"Brugia malayi","qualifier_ui":"Q000276","qualifier_name":"immunology","is_major_topic":true},{"descriptor_ui":"D017385","descriptor_name":"Sequence Homology","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D017421","descriptor_name":"Sequence Analysis","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D017931","descriptor_name":"DNA Primers","qualifier_ui":"Q000737","qualifier_name":"chemistry","is_major_topic":false}],"locations_count":4,"locations":[{"id":"doi:10.1007/bf03401655","doi":"https://doi.org/10.1007/bf03401655","is_oa":true,"landing_page_url":"https://doi.org/10.1007/bf03401655","pdf_url":"https://molmed.biomedcentral.com/track/pdf/10.1007/BF03401655","source":{"id":"https://openalex.org/S6769275","display_name":"Molecular Medicine","issn_l":"1076-1551","issn":["1076-1551","1528-3658"],"is_oa":false,"is_in_doaj":true,"is_core":true,"listed_in":["cwts-core","doaj","dongbi-d","doyens","jufo-1","ki-jl-1","medline","norway-1","oarl","poland-100","russia-white-list-1"],"host_organization":"https://openalex.org/P4310320256","host_organization_name":"BioMed Central","host_organization_lineage":["https://openalex.org/P4310320256","https://openalex.org/P4310319965"],"host_organization_lineage_names":["BioMed Central","Springer Nature"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Molecular Medicine","raw_type":"journal-article"},{"id":"pmh:oai:pubmedcentral.nih.gov:2230135","doi":null,"is_oa":true,"landing_page_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/2230135","pdf_url":null,"source":{"id":"https://openalex.org/S2764455111","display_name":"PubMed Central","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Mol Med","raw_type":"Text"},{"id":"pmid:8972486","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/8972486","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Molecular medicine (Cambridge, Mass.)","raw_type":"Journal Article"},{"id":"mag:161931260","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/8972486","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":null,"is_accepted":false,"is_published":false,"raw_source_name":"PubMed","raw_type":null}],"best_oa_location":{"id":"doi:10.1007/bf03401655","doi":"https://doi.org/10.1007/bf03401655","is_oa":true,"landing_page_url":"https://doi.org/10.1007/bf03401655","pdf_url":"https://molmed.biomedcentral.com/track/pdf/10.1007/BF03401655","source":{"id":"https://openalex.org/S6769275","display_name":"Molecular Medicine","issn_l":"1076-1551","issn":["1076-1551","1528-3658"],"is_oa":false,"is_in_doaj":true,"is_core":true,"listed_in":["cwts-core","doaj","dongbi-d","doyens","jufo-1","ki-jl-1","medline","norway-1","oarl","poland-100","russia-white-list-1"],"host_organization":"https://openalex.org/P4310320256","host_organization_name":"BioMed Central","host_organization_lineage":["https://openalex.org/P4310320256","https://openalex.org/P4310319965"],"host_organization_lineage_names":["BioMed Central","Springer Nature"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Molecular Medicine","raw_type":"journal-article"},"sustainable_development_goals":[{"display_name":"Good health and well-being","score":0.8199999928474426,"id":"https://metadata.un.org/sdg/3"}],"study_designs":[],"awards":[{"id":"https://openalex.org/G3384203622","display_name":"Studies of the role of recombinant filarial allergens in the pathology of pulmonary eosinophilia","funder_award_id":"42495","funder_id":"https://openalex.org/F4320320924","funder_display_name":"Schweizerischer Nationalfonds zur F\u00f6rderung der Wissenschaftlichen Forschung"}],"funders":[{"id":"https://openalex.org/F4320306076","display_name":"National Science Foundation","ror":"https://ror.org/021nxhr62"},{"id":"https://openalex.org/F4320310466","display_name":"Universit\u00e4t Basel","ror":"https://ror.org/02s6k3f65"},{"id":"https://openalex.org/F4320320924","display_name":"Schweizerischer Nationalfonds zur F\u00f6rderung der Wissenschaftlichen Forschung","ror":"https://ror.org/00yjd3n13"}],"has_content":{"pdf":true,"grobid_xml":true},"content_urls":{"pdf":"https://content.openalex.org/works/W4322697114.pdf","grobid_xml":"https://content.openalex.org/works/W4322697114.grobid-xml"},"referenced_works_count":49,"referenced_works":["https://openalex.org/W182091540","https://openalex.org/W436833533","https://openalex.org/W561754329","https://openalex.org/W1525654343","https://openalex.org/W1533193661","https://openalex.org/W1550626060","https://openalex.org/W1604298442","https://openalex.org/W1900191660","https://openalex.org/W1902048847","https://openalex.org/W1943367294","https://openalex.org/W1963907257","https://openalex.org/W1965952831","https://openalex.org/W1967589959","https://openalex.org/W1971256855","https://openalex.org/W1974055365","https://openalex.org/W1975304761","https://openalex.org/W1975488965","https://openalex.org/W1991648320","https://openalex.org/W2008416160","https://openalex.org/W2013470743","https://openalex.org/W2018289835","https://openalex.org/W2024910829","https://openalex.org/W2027751497","https://openalex.org/W2036589422","https://openalex.org/W2045817286","https://openalex.org/W2046281538","https://openalex.org/W2050925795","https://openalex.org/W2053493238","https://openalex.org/W2054533662","https://openalex.org/W2064587910","https://openalex.org/W2074112270","https://openalex.org/W2075004701","https://openalex.org/W2085340957","https://openalex.org/W2100837269","https://openalex.org/W2101108802","https://openalex.org/W2110831762","https://openalex.org/W2121437105","https://openalex.org/W2124030177","https://openalex.org/W2128635872","https://openalex.org/W2136060598","https://openalex.org/W2138270253","https://openalex.org/W2138879032","https://openalex.org/W2154128645","https://openalex.org/W2286301987","https://openalex.org/W2395071541","https://openalex.org/W2407900194","https://openalex.org/W2545636411","https://openalex.org/W4239669946","https://openalex.org/W4302889956"],"related_works":["https://openalex.org/W161931260","https://openalex.org/W1865263763","https://openalex.org/W7097318891","https://openalex.org/W1902048847","https://openalex.org/W2001032004","https://openalex.org/W1990323753","https://openalex.org/W2111853426","https://openalex.org/W4389322693","https://openalex.org/W2023270822","https://openalex.org/W1991337485"],"abstract_inverted_index":null,"counts_by_year":[{"year":2024,"cited_by_count":1},{"year":2023,"cited_by_count":2},{"year":2021,"cited_by_count":1},{"year":2017,"cited_by_count":1},{"year":2013,"cited_by_count":2},{"year":2012,"cited_by_count":2}],"updated_date":"2026-11-07T11:25:07.637180","created_date":"2023-03-02T00:00:00"}