{"id":"https://openalex.org/W4320205845","doi":"https://doi.org/10.3390/molecules28041718","title":"Chemical and Biological Review of Endophytic Fungi Associated with Morus sp. (Moraceae) and In Silico Study of Their Antidiabetic Potential","display_name":"Chemical and Biological Review of Endophytic Fungi Associated with Morus sp. (Moraceae) and In Silico Study of Their Antidiabetic Potential","publication_year":2023,"publication_date":"2023-02-10","ids":{"openalex":"https://openalex.org/W4320205845","doi":"https://doi.org/10.3390/molecules28041718","pmid":"https://pubmed.ncbi.nlm.nih.gov/36838706","pmcid":"https://www.ncbi.nlm.nih.gov/pmc/articles/9968060"},"language":"en","primary_location":{"id":"doi:10.3390/molecules28041718","doi":"https://doi.org/10.3390/molecules28041718","is_oa":true,"landing_page_url":"https://doi.org/10.3390/molecules28041718","pdf_url":"https://www.mdpi.com/1420-3049/28/4/1718/pdf?version=1677050896","source":{"id":"https://openalex.org/S108911230","display_name":"Molecules","issn_l":"1420-3049","issn":["1420-3049","1433-1373"],"is_oa":true,"is_in_doaj":true,"is_core":true,"listed_in":["anvur-scientific","cwts-core","doaj","medline","poland-140","russia-white-list-1"],"host_organization":"https://openalex.org/P4310310987","host_organization_name":"Multidisciplinary Digital Publishing Institute","host_organization_lineage":["https://openalex.org/P4310310987"],"host_organization_lineage_names":["Multidisciplinary Digital Publishing Institute"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Molecules","raw_type":"journal-article"},"volume":null,"type":"review","is_traditional":true,"indexed_in":["crossref","doaj","pubmed"],"open_access":{"is_oa":true,"oa_status":"gold","oa_url":"https://www.mdpi.com/1420-3049/28/4/1718/pdf?version=1677050896","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5028156257","display_name":"Mohamed M. M. AbdelRazek","orcid":"https://orcid.org/0000-0001-5705-3806","observed_orcids":["https://orcid.org/0000-0001-5705-3806"]},"institutions":[{"id":"https://openalex.org/I4210151980","display_name":"Badr University in Cairo","ror":"https://ror.org/04tbvjc27","country_code":"EG","type":"education","lineage":["https://openalex.org/I4210151980"]}],"countries":["EG"],"is_corresponding":false,"raw_author_name":"Mohamed M. M. AbdelRazek","raw_affiliation_strings":["Department of Pharmacognosy, Faculty of Pharmacy, Badr University in Cairo (BUC), Cairo 11829, Egypt"],"raw_orcid":"https://orcid.org/0000-0001-5705-3806","affiliations":[{"raw_affiliation_string":"Department of Pharmacognosy, Faculty of Pharmacy, Badr University in Cairo (BUC), Cairo 11829, Egypt","institution_ids":["https://openalex.org/I4210151980"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5081019108","display_name":"Ahmed M. Elissawy","orcid":"https://orcid.org/0000-0003-1584-7653","observed_orcids":["https://orcid.org/0000-0003-1584-7653"]},"institutions":[{"id":"https://openalex.org/I107720978","display_name":"Ain Shams University","ror":"https://ror.org/00cb9w016","country_code":"EG","type":"education","lineage":["https://openalex.org/I107720978"]}],"countries":["EG"],"is_corresponding":false,"raw_author_name":"Ahmed M. Elissawy","raw_affiliation_strings":["Center of Drug Discovery Research and Development, Ain Shams University, Cairo 11566, Egypt","Department of Pharmacognosy, Faculty of Pharmacy, Ain Shams University, Cairo 11566, Egypt"],"raw_orcid":"https://orcid.org/0000-0003-1584-7653","affiliations":[{"raw_affiliation_string":"Center of Drug Discovery Research and Development, Ain Shams University, Cairo 11566, Egypt","institution_ids":["https://openalex.org/I107720978"]},{"raw_affiliation_string":"Department of Pharmacognosy, Faculty of Pharmacy, Ain Shams University, Cairo 11566, Egypt","institution_ids":["https://openalex.org/I107720978"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5024297624","display_name":"Nada M. Mostafa","orcid":"https://orcid.org/0000-0003-1602-2725","observed_orcids":["https://orcid.org/0000-0003-1602-2725"]},"institutions":[{"id":"https://openalex.org/I107720978","display_name":"Ain Shams University","ror":"https://ror.org/00cb9w016","country_code":"EG","type":"education","lineage":["https://openalex.org/I107720978"]}],"countries":["EG"],"is_corresponding":false,"raw_author_name":"Nada M. Mostafa","raw_affiliation_strings":["Department of Pharmacognosy, Faculty of Pharmacy, Ain Shams University, Cairo 11566, Egypt"],"raw_orcid":"https://orcid.org/0000-0003-1602-2725","affiliations":[{"raw_affiliation_string":"Department of Pharmacognosy, Faculty of Pharmacy, Ain Shams University, Cairo 11566, Egypt","institution_ids":["https://openalex.org/I107720978"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5042338040","display_name":"Ashaimaa Yehia Moussa","orcid":"https://orcid.org/0000-0001-7818-3319","observed_orcids":["https://orcid.org/0000-0001-7818-3319"]},"institutions":[{"id":"https://openalex.org/I107720978","display_name":"Ain Shams University","ror":"https://ror.org/00cb9w016","country_code":"EG","type":"education","lineage":["https://openalex.org/I107720978"]}],"countries":["EG"],"is_corresponding":false,"raw_author_name":"Ashaimaa Y. Moussa","raw_affiliation_strings":["Department of Pharmacognosy, Faculty of Pharmacy, Ain Shams University, Cairo 11566, Egypt"],"raw_orcid":"https://orcid.org/0000-0001-7818-3319","affiliations":[{"raw_affiliation_string":"Department of Pharmacognosy, Faculty of Pharmacy, Ain Shams University, Cairo 11566, Egypt","institution_ids":["https://openalex.org/I107720978"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5034807820","display_name":"Mohamed A. Elanany","orcid":"https://orcid.org/0000-0002-1784-8572","observed_orcids":["https://orcid.org/0000-0002-1784-8572"]},"institutions":[{"id":"https://openalex.org/I4210151980","display_name":"Badr University in Cairo","ror":"https://ror.org/04tbvjc27","country_code":"EG","type":"education","lineage":["https://openalex.org/I4210151980"]}],"countries":["EG"],"is_corresponding":false,"raw_author_name":"Mohamed A. Elanany","raw_affiliation_strings":["Department of Pharmaceutical Chemistry, Faculty of Pharmacy, Badr University in Cairo (BUC), Cairo 11829, Egypt"],"raw_orcid":"https://orcid.org/0000-0002-1784-8572","affiliations":[{"raw_affiliation_string":"Department of Pharmaceutical Chemistry, Faculty of Pharmacy, Badr University in Cairo (BUC), Cairo 11829, Egypt","institution_ids":["https://openalex.org/I4210151980"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5013907723","display_name":"Mohamed Ahmed El-Shanawany","orcid":"https://orcid.org/0000-0003-2412-8490","observed_orcids":["https://orcid.org/0000-0003-2412-8490"]},"institutions":[{"id":"https://openalex.org/I4210151980","display_name":"Badr University in Cairo","ror":"https://ror.org/04tbvjc27","country_code":"EG","type":"education","lineage":["https://openalex.org/I4210151980"]}],"countries":["EG"],"is_corresponding":false,"raw_author_name":"Mohamed A. Elshanawany","raw_affiliation_strings":["Department of Pharmacognosy, Faculty of Pharmacy, Badr University in Cairo (BUC), Cairo 11829, Egypt"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Pharmacognosy, Faculty of Pharmacy, Badr University in Cairo (BUC), Cairo 11829, Egypt","institution_ids":["https://openalex.org/I4210151980"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5015959877","display_name":"Abdel Nasser B. Singab","orcid":"https://orcid.org/0000-0001-7445-963X","observed_orcids":["https://orcid.org/0000-0001-7445-963X"]},"institutions":[{"id":"https://openalex.org/I107720978","display_name":"Ain Shams University","ror":"https://ror.org/00cb9w016","country_code":"EG","type":"education","lineage":["https://openalex.org/I107720978"]}],"countries":["EG"],"is_corresponding":true,"raw_author_name":"Abdel Nasser B. Singab","raw_affiliation_strings":["Center of Drug Discovery Research and Development, Ain Shams University, Cairo 11566, Egypt","Department of Pharmacognosy, Faculty of Pharmacy, Ain Shams University, Cairo 11566, Egypt"],"raw_orcid":"https://orcid.org/0000-0001-7445-963X","affiliations":[{"raw_affiliation_string":"Center of Drug Discovery Research and Development, Ain Shams University, Cairo 11566, Egypt","institution_ids":["https://openalex.org/I107720978"]},{"raw_affiliation_string":"Department of Pharmacognosy, Faculty of Pharmacy, Ain Shams University, Cairo 11566, Egypt","institution_ids":["https://openalex.org/I107720978"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":2,"corresponding_author_ids":["https://openalex.org/A5015959877"],"corresponding_institution_ids":["https://openalex.org/I107720978"],"apc_list":{"value":2300,"currency":"CHF","value_usd":2558},"apc_paid":{"value":2300,"currency":"CHF","value_usd":2558},"fwci":0.7033,"has_fulltext":true,"cited_by_count":29,"citation_normalized_percentile":{"value":0.55384615,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":98,"max":99},"biblio":{"volume":"28","issue":"4","first_page":"1718","last_page":"1718"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10252","display_name":"Microbial Natural Products and Biosynthesis","score":0.9613999724388123,"subfield":{"id":"https://openalex.org/subfields/2402","display_name":"Applied Microbiology and Biotechnology"},"field":{"id":"https://openalex.org/fields/24","display_name":"Immunology and Microbiology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T10252","display_name":"Microbial Natural Products and Biosynthesis","score":0.9613999724388123,"subfield":{"id":"https://openalex.org/subfields/2402","display_name":"Applied Microbiology and Biotechnology"},"field":{"id":"https://openalex.org/fields/24","display_name":"Immunology and Microbiology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T12934","display_name":"Plant and fungal interactions","score":0.008100000210106373,"subfield":{"id":"https://openalex.org/subfields/1105","display_name":"Ecology, Evolution, Behavior and Systematics"},"field":{"id":"https://openalex.org/fields/11","display_name":"Agricultural and Biological Sciences"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T12257","display_name":"Bioactive natural compounds","score":0.004000000189989805,"subfield":{"id":"https://openalex.org/subfields/3002","display_name":"Drug Discovery"},"field":{"id":"https://openalex.org/fields/30","display_name":"Pharmacology, Toxicology and Pharmaceutics"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/endophytic-fungi","display_name":"endophytic fungi","score":0.9990000128746033},{"id":"https://openalex.org/keywords/mulberry","display_name":"mulberry","score":0.9929999709129333},{"id":"https://openalex.org/keywords/antidiabetic-activity","display_name":"antidiabetic activity","score":0.7940000295639038},{"id":"https://openalex.org/keywords/diabetes-mellitus","display_name":"diabetes mellitus","score":0.9049999713897705},{"id":"https://openalex.org/keywords/alpha-amylase-inhibition","display_name":"\u03b1-amylase inhibition","score":0.9179999828338623},{"id":"https://openalex.org/keywords/sglt2-inhibition","display_name":"SGLT2 inhibition","score":0.8790000081062317},{"id":"https://openalex.org/keywords/molecular-docking","display_name":"molecular docking","score":0.7160000205039978},{"id":"https://openalex.org/keywords/pharmacokinetics","display_name":"pharmacokinetics","score":0.7940000295639038},{"id":"https://openalex.org/keywords/dynamic-stability","display_name":"dynamic stability","score":0.5860000252723694},{"id":"https://openalex.org/keywords/fungal-metabolites","display_name":"fungal metabolites","score":0.7049999833106995},{"id":"https://openalex.org/keywords/medicinal-plants","display_name":"medicinal plants","score":0.6489999890327454}],"concepts":[{"id":"https://openalex.org/C2775905019","wikidata":"https://www.wikidata.org/wiki/Q192572","display_name":"In silico","level":3,"score":0.8811795115470886},{"id":"https://openalex.org/C89638049","wikidata":"https://www.wikidata.org/wiki/Q7201546","display_name":"Plant use of endophytic fungi in defense","level":2,"score":0.7323219776153564},{"id":"https://openalex.org/C2780255822","wikidata":"https://www.wikidata.org/wiki/Q156579","display_name":"Moraceae","level":2,"score":0.6034367084503174},{"id":"https://openalex.org/C556039675","wikidata":"https://www.wikidata.org/wiki/Q771035","display_name":"Traditional medicine","level":1,"score":0.4543326497077942},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.43529802560806274},{"id":"https://openalex.org/C185592680","wikidata":"https://www.wikidata.org/wiki/Q2329","display_name":"Chemistry","level":0,"score":0.345052033662796},{"id":"https://openalex.org/C70721500","wikidata":"https://www.wikidata.org/wiki/Q177005","display_name":"Computational biology","level":1,"score":0.3420584201812744},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.24896544218063354},{"id":"https://openalex.org/C59822182","wikidata":"https://www.wikidata.org/wiki/Q441","display_name":"Botany","level":1,"score":0.23250699043273926},{"id":"https://openalex.org/C55493867","wikidata":"https://www.wikidata.org/wiki/Q7094","display_name":"Biochemistry","level":1,"score":0.23137176036834717},{"id":"https://openalex.org/C104317684","wikidata":"https://www.wikidata.org/wiki/Q7187","display_name":"Gene","level":2,"score":0.0}],"mesh":[{"descriptor_ui":"D005658","descriptor_name":"Fungi","qualifier_ui":"Q000737","qualifier_name":"chemistry","is_major_topic":true},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D007004","descriptor_name":"Hypoglycemic Agents","qualifier_ui":"Q000494","qualifier_name":"pharmacology","is_major_topic":true},{"descriptor_ui":"D031625","descriptor_name":"Morus","qualifier_ui":"Q000382","qualifier_name":"microbiology","is_major_topic":true},{"descriptor_ui":"D060026","descriptor_name":"Endophytes","qualifier_ui":"Q000737","qualifier_name":"chemistry","is_major_topic":true},{"descriptor_ui":"D062105","descriptor_name":"Molecular Docking Simulation","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false}],"locations_count":4,"locations":[{"id":"doi:10.3390/molecules28041718","doi":"https://doi.org/10.3390/molecules28041718","is_oa":true,"landing_page_url":"https://doi.org/10.3390/molecules28041718","pdf_url":"https://www.mdpi.com/1420-3049/28/4/1718/pdf?version=1677050896","source":{"id":"https://openalex.org/S108911230","display_name":"Molecules","issn_l":"1420-3049","issn":["1420-3049","1433-1373"],"is_oa":true,"is_in_doaj":true,"is_core":true,"listed_in":["anvur-scientific","cwts-core","doaj","medline","poland-140","russia-white-list-1"],"host_organization":"https://openalex.org/P4310310987","host_organization_name":"Multidisciplinary Digital Publishing Institute","host_organization_lineage":["https://openalex.org/P4310310987"],"host_organization_lineage_names":["Multidisciplinary Digital Publishing Institute"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Molecules","raw_type":"journal-article"},{"id":"pmh:oai:pubmedcentral.nih.gov:9968060","doi":null,"is_oa":true,"landing_page_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/9968060","pdf_url":null,"source":{"id":"https://openalex.org/S2764455111","display_name":"PubMed Central","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Molecules","raw_type":"Text"},{"id":"pmid:36838706","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/36838706","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Molecules (Basel, Switzerland)","raw_type":"Review"},{"id":"pmh:oai:doaj.org/article:e0f993417799472d9409c5391bf58c2d","doi":null,"is_oa":true,"landing_page_url":"https://doaj.org/article/e0f993417799472d9409c5391bf58c2d","pdf_url":null,"source":{"id":"https://openalex.org/S4306401280","display_name":"DOAJ (DOAJ: Directory of Open Access Journals)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by-sa","license_id":"https://openalex.org/licenses/cc-by-sa","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"Molecules, Vol 28, Iss 4, p 1718 (2023)","raw_type":"article"}],"best_oa_location":{"id":"doi:10.3390/molecules28041718","doi":"https://doi.org/10.3390/molecules28041718","is_oa":true,"landing_page_url":"https://doi.org/10.3390/molecules28041718","pdf_url":"https://www.mdpi.com/1420-3049/28/4/1718/pdf?version=1677050896","source":{"id":"https://openalex.org/S108911230","display_name":"Molecules","issn_l":"1420-3049","issn":["1420-3049","1433-1373"],"is_oa":true,"is_in_doaj":true,"is_core":true,"listed_in":["anvur-scientific","cwts-core","doaj","medline","poland-140","russia-white-list-1"],"host_organization":"https://openalex.org/P4310310987","host_organization_name":"Multidisciplinary Digital Publishing Institute","host_organization_lineage":["https://openalex.org/P4310310987"],"host_organization_lineage_names":["Multidisciplinary Digital Publishing Institute"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Molecules","raw_type":"journal-article"},"sustainable_development_goals":[{"score":0.9391000270843506,"id":"https://metadata.un.org/sdg/3","display_name":"Good health and well-being"}],"study_designs":[],"awards":[],"funders":[],"has_content":{"grobid_xml":true,"pdf":true},"content_urls":{"pdf":"https://content.openalex.org/works/W4320205845.pdf","grobid_xml":"https://content.openalex.org/works/W4320205845.grobid-xml"},"referenced_works_count":72,"referenced_works":["https://openalex.org/W1887624773","https://openalex.org/W1894646060","https://openalex.org/W1975770902","https://openalex.org/W1980555036","https://openalex.org/W1995271072","https://openalex.org/W2001877180","https://openalex.org/W2003876274","https://openalex.org/W2059796456","https://openalex.org/W2085663480","https://openalex.org/W2093765481","https://openalex.org/W2106649651","https://openalex.org/W2134967712","https://openalex.org/W2169678694","https://openalex.org/W2171852220","https://openalex.org/W2257452859","https://openalex.org/W2410035347","https://openalex.org/W2513874912","https://openalex.org/W2516696348","https://openalex.org/W2593436234","https://openalex.org/W2602243144","https://openalex.org/W2610249362","https://openalex.org/W2613261853","https://openalex.org/W2800661980","https://openalex.org/W2804840464","https://openalex.org/W2810428191","https://openalex.org/W2898421299","https://openalex.org/W2905442871","https://openalex.org/W2924305165","https://openalex.org/W2942287302","https://openalex.org/W2947117088","https://openalex.org/W2989939079","https://openalex.org/W2996900550","https://openalex.org/W2997816379","https://openalex.org/W3015781427","https://openalex.org/W3021422796","https://openalex.org/W3026374106","https://openalex.org/W3041804410","https://openalex.org/W3080088262","https://openalex.org/W3091926957","https://openalex.org/W3097777234","https://openalex.org/W3107062700","https://openalex.org/W3108259629","https://openalex.org/W3109545552","https://openalex.org/W3117780434","https://openalex.org/W3127750715","https://openalex.org/W3128055812","https://openalex.org/W3133523139","https://openalex.org/W3153196298","https://openalex.org/W3155931852","https://openalex.org/W3161000711","https://openalex.org/W3161597332","https://openalex.org/W3162357213","https://openalex.org/W3164279443","https://openalex.org/W3167019654","https://openalex.org/W3181619892","https://openalex.org/W3197724709","https://openalex.org/W3207022508","https://openalex.org/W4200207822","https://openalex.org/W4200312896","https://openalex.org/W4200385078","https://openalex.org/W4200621660","https://openalex.org/W4205367839","https://openalex.org/W4205581087","https://openalex.org/W4206509456","https://openalex.org/W4210544646","https://openalex.org/W4210779825","https://openalex.org/W4213247307","https://openalex.org/W4220669494","https://openalex.org/W4281560412","https://openalex.org/W4281789995","https://openalex.org/W4284961083","https://openalex.org/W6885049661"],"related_works":["https://openalex.org/W4384922643","https://openalex.org/W2942287302","https://openalex.org/W2328589456","https://openalex.org/W6976682330","https://openalex.org/W4392111202","https://openalex.org/W3162357213","https://openalex.org/W3155931852","https://openalex.org/W4327752658","https://openalex.org/W2320586982","https://openalex.org/W2897899215"],"abstract_inverted_index":{"The":[0,16,73],"chronic":[1],"nature":[2],"of":[3,22,32,86,97,155,180,185],"diabetes":[4],"mellitus":[5],"motivates":[6],"the":[7,49,63,79,98,119,153,156,161,181],"quest":[8],"for":[9,43,95],"novel":[10],"agents":[11],"to":[12,28,62,112,123,152],"improve":[13],"its":[14],"management.":[15],"scarcity":[17],"and":[18,56,70,84,131,160],"prior":[19],"uncontrolled":[20],"utilization":[21],"medicinal":[23],"plants":[24],"have":[25,37],"encouraged":[26,110],"researchers":[27],"seek":[29],"new":[30],"sources":[31,42],"promising":[33,148],"compounds.":[34,108,139],"Recently,":[35],"endophytes":[36],"presented":[38],"as":[39],"eco-friendly":[40],"leading":[41],"bioactive":[44],"metabolites.":[45],"This":[46,109],"article":[47],"reviewed":[48],"endophytic":[50,100,187],"fungi":[51],"associated":[52],"with":[53,169],"Morus":[54,186],"species":[55],"their":[57,68,104,125],"isolated":[58,107,121],"compounds,":[59],"in":[60,115,177],"addition":[61],"biological":[64],"activities":[65],"tested":[66],"on":[67,118,137],"extracts":[69,102],"chemical":[71],"constituents.":[72],"relevant":[74],"literature":[75],"was":[76,93],"collected":[77],"from":[78,82],"years":[80],"2008\u20132022":[81],"PubMed":[83],"Web":[85],"Science":[87],"databases.":[88],"Notably,":[89],"no":[90],"antidiabetic":[91,127,149],"activity":[92,150],"reported":[94],"any":[96],"Morus-associated":[99],"fungal":[101],"or":[103],"twenty-one":[105],"previously":[106,120],"us":[111],"perform":[113],"an":[114,176],"silico":[116,178],"study":[117,191],"compounds":[122],"explore":[124],"possible":[126,182],"potential.":[128],"Furthermore,":[129],"pharmacokinetic":[130,171],"dynamic":[132],"stability":[133],"studies":[134],"were":[135],"performed":[136],"these":[138],"Upon":[140],"molecular":[141],"docking,":[142],"Colletotrichalactone":[143],"A":[144],"(14)":[145],"showed":[146],"a":[147],"due":[151],"inhibition":[154],"\u03b1-amylase":[157],"local":[158],"target":[159,168],"human":[162],"sodium-glucose":[163],"cotransporter":[164],"2":[165],"(hSGT2)":[166],"systemic":[167],"safe":[170],"features.":[172],"These":[173],"results":[174],"provide":[175],"interpretation":[179],"anti-diabetic":[183],"potential":[184],"metabolites,":[188],"yet":[189],"further":[190],"is":[192],"required.":[193]},"counts_by_year":[{"year":2026,"cited_by_count":8},{"year":2025,"cited_by_count":7},{"year":2024,"cited_by_count":14}],"updated_date":"2026-11-04T10:54:05.112534","created_date":"2023-02-13T00:00:00"}