{"id":"https://openalex.org/W4320021241","doi":"https://doi.org/10.54203/scil.2022.wvj56","title":"Development of an Aggressive Treatment Protocol against Neonatal Calf Diarrhea: The Last Chance to Rescue Severely Infected Calves","display_name":"Development of an Aggressive Treatment Protocol against Neonatal Calf Diarrhea: The Last Chance to Rescue Severely Infected Calves","publication_year":2022,"publication_date":"2022-12-25","ids":{"openalex":"https://openalex.org/W4320021241","doi":"https://doi.org/10.54203/scil.2022.wvj56"},"language":"en","primary_location":{"id":"doi:10.54203/scil.2022.wvj56","doi":"https://doi.org/10.54203/scil.2022.wvj56","is_oa":true,"landing_page_url":"https://doi.org/10.54203/scil.2022.wvj56","pdf_url":"http://dx.doi.org/10.54203/scil.2022.wvj56","source":{"id":"https://openalex.org/S4210197741","display_name":"World s Veterinary Journal","issn_l":"2322-4568","issn":["2322-4568"],"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":["poland-20","russia-white-list-4"],"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"World's Veterinary Journal","raw_type":"journal-article"},"volume":null,"type":"article","is_traditional":true,"indexed_in":["crossref"],"open_access":{"is_oa":true,"oa_status":"bronze","oa_url":"http://dx.doi.org/10.54203/scil.2022.wvj56","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5091772394","display_name":"Masoud Alimirzaei","orcid":"https://orcid.org/0000-0001-8320-5666","observed_orcids":["https://orcid.org/0000-0001-8320-5666"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Masoud Alimirzaei","raw_affiliation_strings":["Behroozi Dairy Co., Tehran, Iran"],"raw_orcid":"https://orcid.org/0000-0001-8320-5666","affiliations":[{"raw_affiliation_string":"Behroozi Dairy Co., Tehran, Iran","institution_ids":[]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5073683253","display_name":"Akbar Nikkhah","orcid":"https://orcid.org/0000-0001-7123-1728","observed_orcids":["https://orcid.org/0000-0001-7123-1728"]},"institutions":[{"id":"https://openalex.org/I4210147767","display_name":"Iran's National Elites Foundation","ror":"https://ror.org/05629dh87","country_code":"IR","type":"government","lineage":["https://openalex.org/I4210147767"]}],"countries":["IR"],"is_corresponding":true,"raw_author_name":"Akbar Nikkhah","raw_affiliation_strings":["Chief Highly Distinguished Professor and Nutritional Scientist, National Elites Foundation, Tehran, Iran"],"raw_orcid":"https://orcid.org/0000-0001-7123-1728","affiliations":[{"raw_affiliation_string":"Chief Highly Distinguished Professor and Nutritional Scientist, National Elites Foundation, Tehran, Iran","institution_ids":["https://openalex.org/I4210147767"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":1,"corresponding_author_ids":["https://openalex.org/A5073683253"],"corresponding_institution_ids":["https://openalex.org/I4210147767"],"apc_list":null,"apc_paid":null,"fwci":0.1734,"has_fulltext":true,"cited_by_count":2,"citation_normalized_percentile":{"value":0.38095768,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":88,"max":95},"biblio":{"volume":null,"issue":null,"first_page":"459","last_page":"461"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T12322","display_name":"Animal health and immunology","score":0.9984999895095825,"subfield":{"id":"https://openalex.org/subfields/1103","display_name":"Animal Science and Zoology"},"field":{"id":"https://openalex.org/fields/11","display_name":"Agricultural and Biological Sciences"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T12322","display_name":"Animal health and immunology","score":0.9984999895095825,"subfield":{"id":"https://openalex.org/subfields/1103","display_name":"Animal Science and Zoology"},"field":{"id":"https://openalex.org/fields/11","display_name":"Agricultural and Biological Sciences"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T11688","display_name":"Microbial infections and disease research","score":0.0003000000142492354,"subfield":{"id":"https://openalex.org/subfields/2404","display_name":"Microbiology"},"field":{"id":"https://openalex.org/fields/24","display_name":"Immunology and Microbiology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10943","display_name":"Escherichia coli research studies","score":0.00019999999494757503,"subfield":{"id":"https://openalex.org/subfields/2404","display_name":"Microbiology"},"field":{"id":"https://openalex.org/fields/24","display_name":"Immunology and Microbiology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/neonatal-calf-diarrhea","display_name":"neonatal calf diarrhea","score":1.0},{"id":"https://openalex.org/keywords/calf-mortality","display_name":"calf mortality","score":0.7580000162124634},{"id":"https://openalex.org/keywords/failure-of-passive-transfer","display_name":"failure of passive transfer","score":0.7960000038146973},{"id":"https://openalex.org/keywords/colostrum-feeding","display_name":"colostrum feeding","score":0.9570000171661377},{"id":"https://openalex.org/keywords/dehydration-assessment","display_name":"dehydration assessment","score":0.7639999985694885},{"id":"https://openalex.org/keywords/early-diagnosis","display_name":"early diagnosis","score":0.6480000019073486},{"id":"https://openalex.org/keywords/sepsis","display_name":"sepsis","score":0.6570000052452087},{"id":"https://openalex.org/keywords/dairy-cows","display_name":"dairy cattle","score":0.32199999690055847}],"concepts":[{"id":"https://openalex.org/C2779802037","wikidata":"https://www.wikidata.org/wiki/Q40878","display_name":"Diarrhea","level":2,"score":0.7806775569915771},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.6872814297676086},{"id":"https://openalex.org/C2779073587","wikidata":"https://www.wikidata.org/wiki/Q192746","display_name":"Colostrum","level":3,"score":0.5496151447296143},{"id":"https://openalex.org/C547646559","wikidata":"https://www.wikidata.org/wiki/Q162297","display_name":"Hygiene","level":2,"score":0.5153619647026062},{"id":"https://openalex.org/C177713679","wikidata":"https://www.wikidata.org/wiki/Q679690","display_name":"Intensive care medicine","level":1,"score":0.4921795427799225},{"id":"https://openalex.org/C2780151969","wikidata":"https://www.wikidata.org/wiki/Q949149","display_name":"Sanitation","level":2,"score":0.4446547329425812},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.14404016733169556},{"id":"https://openalex.org/C203014093","wikidata":"https://www.wikidata.org/wiki/Q101929","display_name":"Immunology","level":1,"score":0.1438257098197937},{"id":"https://openalex.org/C142724271","wikidata":"https://www.wikidata.org/wiki/Q7208","display_name":"Pathology","level":1,"score":0.10857269167900085},{"id":"https://openalex.org/C159654299","wikidata":"https://www.wikidata.org/wiki/Q79460","display_name":"Antibody","level":2,"score":0.0}],"mesh":[],"locations_count":2,"locations":[{"id":"doi:10.54203/scil.2022.wvj56","doi":"https://doi.org/10.54203/scil.2022.wvj56","is_oa":true,"landing_page_url":"https://doi.org/10.54203/scil.2022.wvj56","pdf_url":"http://dx.doi.org/10.54203/scil.2022.wvj56","source":{"id":"https://openalex.org/S4210197741","display_name":"World s Veterinary Journal","issn_l":"2322-4568","issn":["2322-4568"],"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":["poland-20","russia-white-list-4"],"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"World's Veterinary Journal","raw_type":"journal-article"},{"id":"pmh:https://cyberleninka.ru/article/n/development-of-an-aggressive-treatment-protocol-against-neonatal-calf-diarrhea-the-last-chance-to-rescue-severely-infected-calves","doi":null,"is_oa":true,"landing_page_url":"https://cyberleninka.ru/article/n/development-of-an-aggressive-treatment-protocol-against-neonatal-calf-diarrhea-the-last-chance-to-rescue-severely-infected-calves","pdf_url":null,"source":{"id":"https://openalex.org/S4306401404","display_name":"CyberLeninK (CyberLeninka)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"","raw_type":"text"}],"best_oa_location":{"id":"doi:10.54203/scil.2022.wvj56","doi":"https://doi.org/10.54203/scil.2022.wvj56","is_oa":true,"landing_page_url":"https://doi.org/10.54203/scil.2022.wvj56","pdf_url":"http://dx.doi.org/10.54203/scil.2022.wvj56","source":{"id":"https://openalex.org/S4210197741","display_name":"World s Veterinary Journal","issn_l":"2322-4568","issn":["2322-4568"],"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":["poland-20","russia-white-list-4"],"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"World's Veterinary Journal","raw_type":"journal-article"},"sustainable_development_goals":[{"score":0.9208999872207642,"display_name":"Zero hunger","id":"https://metadata.un.org/sdg/2"},{"score":0.8560000061988831,"display_name":"Good health and well-being","id":"https://metadata.un.org/sdg/3"}],"study_designs":[],"awards":[],"funders":[],"has_content":{"grobid_xml":true,"pdf":true},"content_urls":{"pdf":"https://content.openalex.org/works/W4320021241.pdf","grobid_xml":"https://content.openalex.org/works/W4320021241.grobid-xml"},"referenced_works_count":8,"referenced_works":["https://openalex.org/W1989014451","https://openalex.org/W2076422270","https://openalex.org/W2505762805","https://openalex.org/W2613065664","https://openalex.org/W2975035154","https://openalex.org/W2990804573","https://openalex.org/W3123251837","https://openalex.org/W3138842959"],"related_works":["https://openalex.org/W2096527134","https://openalex.org/W2154544908","https://openalex.org/W2107914276","https://openalex.org/W2744816872","https://openalex.org/W27238634","https://openalex.org/W189334209","https://openalex.org/W2899307019","https://openalex.org/W2773322513","https://openalex.org/W213054988","https://openalex.org/W2417371469"],"abstract_inverted_index":{"Despite":[0],"many":[1],"efforts":[2],"to":[3,29,37,114,127,134,161,270],"control":[4],"and":[5,31,62,81,86,103,131,139,150,166,171,190,206,222,239,261],"treat":[6],"neonatal":[7],"calf":[8,17,79,116,180],"diarrhea":[9,47,93,183],"(NCD),":[10],"it":[11,213],"remains":[12],"the":[13,66,78,109,119,135,179,193,232,267],"primary":[14],"cause":[15],"of":[16,25,46,68,72,77,121,137,142,147,152,168,195,200,235],"mortality":[18],"in":[19,91,94,246,263],"dairy":[20],"herds":[21],"worldwide.":[22],"The":[23,44],"objective":[24],"this":[26,264],"article":[27,265],"was":[28,259],"develop":[30],"discuss":[32],"an":[33,254],"empirical":[34],"therapeutic":[35],"protocol":[36,258],"save":[38],"newborn":[39],"calves":[40,69,144,249,273],"with":[41,70],"severe":[42,162,172],"diarrhea.":[43,117],"pathophysiology":[45],"has":[48],"been":[49],"well":[50],"described":[51],"previously.":[52],"However,":[53,225],"there":[54],"is":[55,214],"a":[56,198],"significant":[57],"gap":[58],"between":[59],"scientific":[60,187],"findings":[61],"practical":[63],"implementations.":[64],"Reducing":[65],"number":[67],"failure":[71],"passive":[73],"transfer,":[74],"regular":[75],"sanitation":[76],"environment,":[80],"optimal":[82,220],"dry":[83],"cow":[84],"nutrition":[85],"management":[87,102,112],"are":[88,107],"fundamental":[89],"measures":[90],"controlling":[92],"commercial":[95],"settings.":[96],"As":[97],"such,":[98],"optimizing":[99],"colostrum":[100],"feeding":[101],"improving":[104],"ambiance":[105],"hygiene":[106],"among":[108],"most":[110],"important":[111],"practices":[113],"prevent":[115],"Nonetheless,":[118],"occurrence":[120],"NCD":[122,155],"would":[123,242],"be":[124,157,209,243],"unavoidable":[125],"due":[126],"its":[128],"multifactorial":[129],"nature":[130],"pathophysiology.":[132],"According":[133],"degree":[136,146],"dehydration":[138],"general":[140],"appearance":[141],"ill":[143],"(e.g.,":[145],"sunken":[148],"eye":[149],"loss":[151],"suck":[153],"reflex),":[154],"can":[156],"classified":[158],"into":[159,178],"mild":[160,170],"cases.":[163,252],"Early":[164],"diagnosis":[165,218],"treatment":[167,184,241,257],"both":[169],"cases":[173],"could":[174],"reduce":[175],"pathogens":[176],"shedding":[177],"environment.":[181],"Notably,":[182],"needs":[185],"profound":[186],"farm":[188],"education":[189],"mentoring":[191],"regarding":[192],"physiology":[194],"NCD.":[196],"Since":[197],"variety":[199],"organisms,":[201],"such":[202],"as":[203,266],"bacteria,":[204],"viruses,":[205],"protozoa,":[207],"may":[208,230],"responsible":[210],"for":[211,227],"NCD,":[212],"evident":[215],"that":[216],"reliable":[217],"requires":[219],"sampling":[221],"laboratory":[223,228],"analysis.":[224],"waiting":[226],"results":[229],"waste":[231],"golden":[233],"time":[234],"treatment.":[236],"Therefore,":[237],"rapid":[238],"decisive":[240],"mandatory,":[244],"especially":[245],"severely":[247],"infected":[248],"or":[250],"sepsis":[251],"Accordingly,":[253],"effective":[255],"aggressive":[256],"developed":[260],"discussed":[262],"last":[268],"chance":[269],"keep":[271],"diarrheic":[272],"alive.":[274]},"counts_by_year":[{"year":2026,"cited_by_count":1},{"year":2023,"cited_by_count":1}],"updated_date":"2026-10-30T12:39:25.321706","created_date":"2023-02-11T00:00:00"}