{"id":"https://openalex.org/W4319083067","doi":"https://doi.org/10.3390/cancers15030959","title":"Exosomal LncRNAs in Gastrointestinal Cancer: Biological Functions and Emerging Clinical Applications","display_name":"Exosomal LncRNAs in Gastrointestinal Cancer: Biological Functions and Emerging Clinical Applications","publication_year":2023,"publication_date":"2023-02-02","ids":{"openalex":"https://openalex.org/W4319083067","doi":"https://doi.org/10.3390/cancers15030959","pmid":"https://pubmed.ncbi.nlm.nih.gov/36765913","pmcid":"https://www.ncbi.nlm.nih.gov/pmc/articles/9913195"},"language":"en","primary_location":{"id":"doi:10.3390/cancers15030959","doi":"https://doi.org/10.3390/cancers15030959","is_oa":true,"landing_page_url":"https://doi.org/10.3390/cancers15030959","pdf_url":"https://www.mdpi.com/2072-6694/15/3/959/pdf?version=1675341127","source":{"id":"https://openalex.org/S168415115","display_name":"Cancers","issn_l":"2072-6694","issn":["2072-6694"],"is_oa":true,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","norway-1","poland-140","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310310987","host_organization_name":"Multidisciplinary Digital Publishing Institute","host_organization_lineage":["https://openalex.org/P4310310987"],"host_organization_lineage_names":["Multidisciplinary Digital Publishing Institute"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Cancers","raw_type":"journal-article"},"volume":null,"type":"review","is_traditional":true,"indexed_in":["crossref","pubmed"],"open_access":{"is_oa":true,"oa_status":"gold","oa_url":"https://www.mdpi.com/2072-6694/15/3/959/pdf?version=1675341127","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5088868069","display_name":"Yuntong Sun","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I115592961","display_name":"Jiangsu University","ror":"https://ror.org/03jc41j30","country_code":"CN","type":"education","lineage":["https://openalex.org/I115592961"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Yuntong Sun","raw_affiliation_strings":["Jiangsu Key Laboratory of Medical Science and Laboratory Medicine, Department of Laboratory Medicine, School of Medicine, Jiangsu University, Zhenjiang 212013, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Jiangsu Key Laboratory of Medical Science and Laboratory Medicine, Department of Laboratory Medicine, School of Medicine, Jiangsu University, Zhenjiang 212013, China","institution_ids":["https://openalex.org/I115592961"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5078483858","display_name":"Fengtian Sun","orcid":"https://orcid.org/0000-0001-6377-225X","observed_orcids":["https://orcid.org/0000-0001-6377-225X"]},"institutions":[{"id":"https://openalex.org/I115592961","display_name":"Jiangsu University","ror":"https://ror.org/03jc41j30","country_code":"CN","type":"education","lineage":["https://openalex.org/I115592961"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Fengtian Sun","raw_affiliation_strings":["Jiangsu Key Laboratory of Medical Science and Laboratory Medicine, Department of Laboratory Medicine, School of Medicine, Jiangsu University, Zhenjiang 212013, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Jiangsu Key Laboratory of Medical Science and Laboratory Medicine, Department of Laboratory Medicine, School of Medicine, Jiangsu University, Zhenjiang 212013, China","institution_ids":["https://openalex.org/I115592961"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5019062173","display_name":"Jianhua Jin","orcid":"https://orcid.org/0000-0001-8051-6338","observed_orcids":["https://orcid.org/0000-0001-8051-6338"]},"institutions":[{"id":"https://openalex.org/I115592961","display_name":"Jiangsu University","ror":"https://ror.org/03jc41j30","country_code":"CN","type":"education","lineage":["https://openalex.org/I115592961"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Jianhua Jin","raw_affiliation_strings":["Wujin Institute of Molecular Diagnostics and Precision Cancer Medicine of Jiangsu University, Wujin Hospital Affiliated with Jiangsu University, Changzhou 213017, China","Jiangsu Key Laboratory of Medical Science and Laboratory Medicine, Department of Laboratory Medicine, School of Medicine, Jiangsu University, Zhenjiang 212013, China","Wujin Hospital Affiliated with Jiangsu University, Changzhou 213017, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Wujin Institute of Molecular Diagnostics and Precision Cancer Medicine of Jiangsu University, Wujin Hospital Affiliated with Jiangsu University, Changzhou 213017, China","institution_ids":["https://openalex.org/I115592961"]},{"raw_affiliation_string":"Jiangsu Key Laboratory of Medical Science and Laboratory Medicine, Department of Laboratory Medicine, School of Medicine, Jiangsu University, Zhenjiang 212013, China","institution_ids":["https://openalex.org/I115592961"]},{"raw_affiliation_string":"Wujin Hospital Affiliated with Jiangsu University, Changzhou 213017, China","institution_ids":["https://openalex.org/I115592961"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5100890302","display_name":"Wenrong Xu","orcid":"https://orcid.org/0000-0003-0903-1973","observed_orcids":["https://orcid.org/0000-0003-0903-1973","https://orcid.org/0000-0002-8973-2210"]},"institutions":[{"id":"https://openalex.org/I115592961","display_name":"Jiangsu University","ror":"https://ror.org/03jc41j30","country_code":"CN","type":"education","lineage":["https://openalex.org/I115592961"]}],"countries":["CN"],"is_corresponding":true,"raw_author_name":"Wenrong Xu","raw_affiliation_strings":["Jiangsu Key Laboratory of Medical Science and Laboratory Medicine, Department of Laboratory Medicine, School of Medicine, Jiangsu University, Zhenjiang 212013, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Jiangsu Key Laboratory of Medical Science and Laboratory Medicine, Department of Laboratory Medicine, School of Medicine, Jiangsu University, Zhenjiang 212013, China","institution_ids":["https://openalex.org/I115592961"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5101585978","display_name":"Hui Qian","orcid":"https://orcid.org/0000-0002-0098-3196","observed_orcids":["https://orcid.org/0000-0002-0098-3196"]},"institutions":[{"id":"https://openalex.org/I115592961","display_name":"Jiangsu University","ror":"https://ror.org/03jc41j30","country_code":"CN","type":"education","lineage":["https://openalex.org/I115592961"]}],"countries":["CN"],"is_corresponding":true,"raw_author_name":"Hui Qian","raw_affiliation_strings":["Jiangsu Key Laboratory of Medical Science and Laboratory Medicine, Department of Laboratory Medicine, School of Medicine, Jiangsu University, Zhenjiang 212013, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Jiangsu Key Laboratory of Medical Science and Laboratory Medicine, Department of Laboratory Medicine, School of Medicine, Jiangsu University, Zhenjiang 212013, China","institution_ids":["https://openalex.org/I115592961"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":1,"corresponding_author_ids":["https://openalex.org/A5100890302","https://openalex.org/A5101585978"],"corresponding_institution_ids":["https://openalex.org/I115592961"],"apc_list":{"value":2600,"currency":"CHF","value_usd":2892},"apc_paid":{"value":2600,"currency":"CHF","value_usd":2892},"fwci":0.336,"has_fulltext":true,"cited_by_count":14,"citation_normalized_percentile":{"value":0.30688798,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":93,"max":98},"biblio":{"volume":"15","issue":"3","first_page":"959","last_page":"959"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10773","display_name":"Extracellular vesicles in disease","score":0.9878000020980835,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T10773","display_name":"Extracellular vesicles in disease","score":0.9878000020980835,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10515","display_name":"Cancer-related molecular mechanisms research","score":0.01140000019222498,"subfield":{"id":"https://openalex.org/subfields/1306","display_name":"Cancer Research"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10062","display_name":"MicroRNA in disease regulation","score":9.999999747378752e-05,"subfield":{"id":"https://openalex.org/subfields/1306","display_name":"Cancer Research"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/exosomes","display_name":"exosomes","score":0.8989999890327454},{"id":"https://openalex.org/keywords/long-non-coding-rna","display_name":"long non-coding RNA","score":0.9890000224113464},{"id":"https://openalex.org/keywords/gastrointestinal-cancer","display_name":"gastrointestinal cancer","score":0.9929999709129333},{"id":"https://openalex.org/keywords/exosomal-lncrna","display_name":"exosomal lncRNA","score":0.8059999942779541},{"id":"https://openalex.org/keywords/tumor-markers","display_name":"tumor markers","score":0.6510000228881836},{"id":"https://openalex.org/keywords/tumor-progression","display_name":"tumor progression","score":0.6039999723434448},{"id":"https://openalex.org/keywords/metastasis","display_name":"metastasis","score":0.9739999771118164},{"id":"https://openalex.org/keywords/angiogenesis","display_name":"angiogenesis","score":0.9639999866485596},{"id":"https://openalex.org/keywords/cancer-stemness","display_name":"cancer stemness","score":0.8790000081062317},{"id":"https://openalex.org/keywords/tumor-immune-microenvironment","display_name":"tumor immune microenvironment","score":0.9739999771118164},{"id":"https://openalex.org/keywords/drug-resistance","display_name":"drug resistance","score":0.9929999709129333}],"concepts":[{"id":"https://openalex.org/C20518536","wikidata":"https://www.wikidata.org/wiki/Q6840469","display_name":"Microvesicles","level":4,"score":0.9170036315917969},{"id":"https://openalex.org/C2779013556","wikidata":"https://www.wikidata.org/wiki/Q181876","display_name":"Metastasis","level":3,"score":0.5914854407310486},{"id":"https://openalex.org/C2780394083","wikidata":"https://www.wikidata.org/wiki/Q539568","display_name":"Angiogenesis","level":2,"score":0.5892854928970337},{"id":"https://openalex.org/C2781261824","wikidata":"https://www.wikidata.org/wiki/Q903634","display_name":"Exosome","level":5,"score":0.5698954463005066},{"id":"https://openalex.org/C502942594","wikidata":"https://www.wikidata.org/wiki/Q3421914","display_name":"Cancer research","level":1,"score":0.567321240901947},{"id":"https://openalex.org/C2776107976","wikidata":"https://www.wikidata.org/wiki/Q1786433","display_name":"Tumor microenvironment","level":3,"score":0.5239056348800659},{"id":"https://openalex.org/C8891405","wikidata":"https://www.wikidata.org/wiki/Q1059","display_name":"Immune system","level":2,"score":0.5218480825424194},{"id":"https://openalex.org/C542804219","wikidata":"https://www.wikidata.org/wiki/Q5526839","display_name":"Gastrointestinal cancer","level":4,"score":0.5079346299171448},{"id":"https://openalex.org/C121608353","wikidata":"https://www.wikidata.org/wiki/Q12078","display_name":"Cancer","level":2,"score":0.5064519643783569},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.4836958050727844},{"id":"https://openalex.org/C60644358","wikidata":"https://www.wikidata.org/wiki/Q128570","display_name":"Bioinformatics","level":1,"score":0.3810911178588867},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.34740930795669556},{"id":"https://openalex.org/C145059251","wikidata":"https://www.wikidata.org/wiki/Q310899","display_name":"microRNA","level":3,"score":0.3245570659637451},{"id":"https://openalex.org/C203014093","wikidata":"https://www.wikidata.org/wiki/Q101929","display_name":"Immunology","level":1,"score":0.2712743282318115},{"id":"https://openalex.org/C526805850","wikidata":"https://www.wikidata.org/wiki/Q188874","display_name":"Colorectal cancer","level":3,"score":0.13913661241531372},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.11524698138237},{"id":"https://openalex.org/C55493867","wikidata":"https://www.wikidata.org/wiki/Q7094","display_name":"Biochemistry","level":1,"score":0.0},{"id":"https://openalex.org/C104317684","wikidata":"https://www.wikidata.org/wiki/Q7187","display_name":"Gene","level":2,"score":0.0}],"mesh":[],"locations_count":3,"locations":[{"id":"doi:10.3390/cancers15030959","doi":"https://doi.org/10.3390/cancers15030959","is_oa":true,"landing_page_url":"https://doi.org/10.3390/cancers15030959","pdf_url":"https://www.mdpi.com/2072-6694/15/3/959/pdf?version=1675341127","source":{"id":"https://openalex.org/S168415115","display_name":"Cancers","issn_l":"2072-6694","issn":["2072-6694"],"is_oa":true,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","norway-1","poland-140","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310310987","host_organization_name":"Multidisciplinary Digital Publishing Institute","host_organization_lineage":["https://openalex.org/P4310310987"],"host_organization_lineage_names":["Multidisciplinary Digital Publishing Institute"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Cancers","raw_type":"journal-article"},{"id":"pmh:oai:pubmedcentral.nih.gov:9913195","doi":null,"is_oa":true,"landing_page_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/9913195","pdf_url":"https://pmc.ncbi.nlm.nih.gov/articles/PMC9913195/pdf/cancers-15-00959.pdf","source":{"id":"https://openalex.org/S2764455111","display_name":"PubMed Central","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Cancers (Basel)","raw_type":"Text"},{"id":"pmid:36765913","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/36765913","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Cancers","raw_type":"Journal Article"}],"best_oa_location":{"id":"doi:10.3390/cancers15030959","doi":"https://doi.org/10.3390/cancers15030959","is_oa":true,"landing_page_url":"https://doi.org/10.3390/cancers15030959","pdf_url":"https://www.mdpi.com/2072-6694/15/3/959/pdf?version=1675341127","source":{"id":"https://openalex.org/S168415115","display_name":"Cancers","issn_l":"2072-6694","issn":["2072-6694"],"is_oa":true,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","norway-1","poland-140","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310310987","host_organization_name":"Multidisciplinary Digital Publishing Institute","host_organization_lineage":["https://openalex.org/P4310310987"],"host_organization_lineage_names":["Multidisciplinary Digital Publishing Institute"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Cancers","raw_type":"journal-article"},"sustainable_development_goals":[{"display_name":"Good health and well-being","score":0.9789000153541565,"id":"https://metadata.un.org/sdg/3"}],"study_designs":[],"awards":[{"id":"https://openalex.org/G2603386428","display_name":null,"funder_award_id":"20220516","funder_id":"https://openalex.org/F4320327518","funder_display_name":"Priority Academic Program Development of Jiangsu Higher Education Institutions"},{"id":"https://openalex.org/G4983877322","display_name":null,"funder_award_id":"BE2020680","funder_id":"https://openalex.org/F4320327518","funder_display_name":"Priority Academic Program Development of Jiangsu Higher Education Institutions"},{"id":"https://openalex.org/G6217149179","display_name":null,"funder_award_id":"SS2018003","funder_id":"https://openalex.org/F4320327518","funder_display_name":"Priority Academic Program Development of Jiangsu Higher Education Institutions"},{"id":"https://openalex.org/G6851073135","display_name":null,"funder_award_id":"BE2020680","funder_id":"https://openalex.org/F4320321410","funder_display_name":"Jiangsu University"}],"funders":[{"id":"https://openalex.org/F4320321410","display_name":"Jiangsu University","ror":"https://ror.org/03jc41j30"},{"id":"https://openalex.org/F4320321605","display_name":"Government of Jiangsu Province","ror":"https://ror.org/004svx814"},{"id":"https://openalex.org/F4320327518","display_name":"Priority Academic Program Development of Jiangsu Higher Education Institutions","ror":null}],"has_content":{"grobid_xml":true,"pdf":true},"content_urls":{"pdf":"https://content.openalex.org/works/W4319083067.pdf","grobid_xml":"https://content.openalex.org/works/W4319083067.grobid-xml"},"referenced_works_count":120,"referenced_works":["https://openalex.org/W1219176874","https://openalex.org/W2072167135","https://openalex.org/W2237672314","https://openalex.org/W2394902547","https://openalex.org/W2593219221","https://openalex.org/W2741977902","https://openalex.org/W2766002642","https://openalex.org/W2793977979","https://openalex.org/W2795902755","https://openalex.org/W2807152260","https://openalex.org/W2850551009","https://openalex.org/W2871099016","https://openalex.org/W2884081591","https://openalex.org/W2897246241","https://openalex.org/W2900756811","https://openalex.org/W2911671599","https://openalex.org/W2921498253","https://openalex.org/W2932887409","https://openalex.org/W2954974465","https://openalex.org/W2965564510","https://openalex.org/W2966064605","https://openalex.org/W2966266646","https://openalex.org/W2978393342","https://openalex.org/W2986438911","https://openalex.org/W2987643595","https://openalex.org/W2990883614","https://openalex.org/W2995121686","https://openalex.org/W2996109785","https://openalex.org/W2997622055","https://openalex.org/W3005104290","https://openalex.org/W3006570557","https://openalex.org/W3012821548","https://openalex.org/W3014713533","https://openalex.org/W3015769226","https://openalex.org/W3023556593","https://openalex.org/W3023784496","https://openalex.org/W3033370201","https://openalex.org/W3033976451","https://openalex.org/W3042078288","https://openalex.org/W3042815763","https://openalex.org/W3045804653","https://openalex.org/W3047244309","https://openalex.org/W3047391822","https://openalex.org/W3083720470","https://openalex.org/W3093297428","https://openalex.org/W3096517545","https://openalex.org/W3096805091","https://openalex.org/W3101769880","https://openalex.org/W3107352906","https://openalex.org/W3109064276","https://openalex.org/W3111273864","https://openalex.org/W3114124584","https://openalex.org/W3119354227","https://openalex.org/W3120593348","https://openalex.org/W3120884777","https://openalex.org/W3122604725","https://openalex.org/W3123711776","https://openalex.org/W3137101949","https://openalex.org/W3138190732","https://openalex.org/W3149234028","https://openalex.org/W3155216659","https://openalex.org/W3156444602","https://openalex.org/W3161167924","https://openalex.org/W3163023941","https://openalex.org/W3165464081","https://openalex.org/W3166088886","https://openalex.org/W3185027737","https://openalex.org/W3185743503","https://openalex.org/W3192520166","https://openalex.org/W3198011172","https://openalex.org/W3198349163","https://openalex.org/W3198759013","https://openalex.org/W3206920707","https://openalex.org/W3206985971","https://openalex.org/W3210462413","https://openalex.org/W3211623136","https://openalex.org/W3211721769","https://openalex.org/W3214368603","https://openalex.org/W4200470336","https://openalex.org/W4205666440","https://openalex.org/W4206051569","https://openalex.org/W4206170275","https://openalex.org/W4210274138","https://openalex.org/W4211255081","https://openalex.org/W4212964448","https://openalex.org/W4213116015","https://openalex.org/W4214772834","https://openalex.org/W4220681776","https://openalex.org/W4220874950","https://openalex.org/W4220961046","https://openalex.org/W4220989298","https://openalex.org/W4221045921","https://openalex.org/W4221133899","https://openalex.org/W4223446268","https://openalex.org/W4223601737","https://openalex.org/W4224884106","https://openalex.org/W4255724971","https://openalex.org/W4280642441","https://openalex.org/W4281766357","https://openalex.org/W4281941428","https://openalex.org/W4283031510","https://openalex.org/W4283325038","https://openalex.org/W4284990246","https://openalex.org/W4284990676","https://openalex.org/W4293368535","https://openalex.org/W4295444209","https://openalex.org/W4296349696","https://openalex.org/W4298616594","https://openalex.org/W4304014081","https://openalex.org/W4306155320","https://openalex.org/W4306652547","https://openalex.org/W4306761522","https://openalex.org/W4306811899","https://openalex.org/W4308679511","https://openalex.org/W4308723732","https://openalex.org/W4310023521","https://openalex.org/W4311019978","https://openalex.org/W4312066000","https://openalex.org/W6838825638","https://openalex.org/W6846041345"],"related_works":["https://openalex.org/W4311377014","https://openalex.org/W4225384758","https://openalex.org/W4313454840","https://openalex.org/W4385616390","https://openalex.org/W4389487458","https://openalex.org/W3085756871","https://openalex.org/W2913281364","https://openalex.org/W3166568105","https://openalex.org/W3217459319","https://openalex.org/W3184692235"],"abstract_inverted_index":{"Due":[0],"to":[1,93,131],"the":[2,12,43,96,105,114,141],"lack":[3],"of":[4,17,25,45,72,108,117],"specific":[5],"and":[6,9,15,85,99,110,112,133,140,143],"effective":[7],"biomarkers":[8,98],"therapeutic":[10],"targets,":[11],"early":[13],"diagnosis":[14,97],"treatment":[16],"gastrointestinal":[18,73,121,135],"cancer":[19,74,122,136],"remain":[20],"unsatisfactory.":[21],"As":[22],"a":[23],"type":[24],"nanosized":[26],"vesicles":[27],"derived":[28],"from":[29],"living":[30],"cells,":[31],"exosomes":[32,109],"mediate":[33],"cell-to-cell":[34],"communication":[35],"by":[36],"transporting":[37],"bioactive":[38],"molecules,":[39],"thus":[40],"participating":[41],"in":[42,61,69,120],"regulation":[44],"many":[46],"pathophysiological":[47],"processes.":[48],"Recent":[49],"evidence":[50],"has":[51],"revealed":[52],"that":[53],"several":[54],"long":[55],"non-coding":[56],"RNAs":[57],"(lncRNAs)":[58],"are":[59,137,151],"enriched":[60],"exosomes.":[62],"Exosomes-mediated":[63],"lncRNAs":[64,89,111,119,130],"delivery":[65],"is":[66],"critically":[67],"involved":[68],"various":[70],"aspects":[71],"progression,":[75],"such":[76],"as":[77,95],"tumor":[78],"proliferation,":[79],"metastasis,":[80],"angiogenesis,":[81],"stemness,":[82],"immune":[83],"microenvironment,":[84],"drug":[86],"resistance.":[87],"Exosomal":[88],"represent":[90],"promising":[91],"candidates":[92],"act":[94],"anti-tumor":[100],"targets.":[101],"This":[102],"review":[103],"introduces":[104],"major":[106],"characteristics":[107],"describes":[113],"biological":[115],"functions":[116],"exosomal":[118,129],"development.":[123],"The":[124],"preclinical":[125],"studies":[126],"on":[127],"using":[128],"monitor":[132],"treat":[134],"also":[138],"discussed,":[139],"opportunities":[142],"challenges":[144],"for":[145],"translating":[146],"them":[147],"into":[148],"clinical":[149],"practice":[150],"evaluated.":[152]},"counts_by_year":[{"year":2026,"cited_by_count":3},{"year":2025,"cited_by_count":6},{"year":2024,"cited_by_count":2},{"year":2023,"cited_by_count":3}],"updated_date":"2026-11-07T11:25:07.637180","created_date":"2023-02-04T00:00:00"}